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theophylline and Leukemia, Promyelocytic, Acute

theophylline has been researched along with Leukemia, Promyelocytic, Acute in 8 studies

Leukemia, Promyelocytic, Acute: An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.

Research Excerpts

ExcerptRelevanceReference
"We show that cyclic AMP (cAMP) elevating agents protect blasts from patients with acute promyelocytic leukemia (APL) against death induced by first-line anti-leukemic anthracyclines like daunorubicin (DNR)."3.79Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis. ( Bruserud, O; Døskeland, SO; Gausdal, G; Gjertsen, BT; Havemann, U; Herfindal, L; Kleppe, R; Lanotte, M; McCormack, E; Nguyen, E; Pendino, F; Rouhee, N; Schwede, F; Ségal-Bendirdjian, E; Skavland, J; Wergeland, A, 2013)
" The most relevant clinical example is acute promyelocytic leukemia (APL), which responds dramatically to either retinoic acid (RA) or arsenic trioxide (As(2)O(3))."3.71In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia. ( Daniel, MT; De Thé, H; Degos, L; Dombret, H; Gourmel, B; Guillemin, MC; Janin, A; Kogan, S; Lallemand-Breitenbach, V; Lanotte, M; Raffoux, E; Soilihi, H; Vitoux, D; Zhu, J, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's4 (50.00)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gausdal, G1
Wergeland, A1
Skavland, J1
Nguyen, E1
Pendino, F1
Rouhee, N1
McCormack, E1
Herfindal, L1
Kleppe, R1
Havemann, U1
Schwede, F1
Bruserud, O1
Gjertsen, BT1
Lanotte, M2
Ségal-Bendirdjian, E1
Døskeland, SO1
Guillemin, MC1
Raffoux, E1
Vitoux, D1
Kogan, S1
Soilihi, H1
Lallemand-Breitenbach, V1
Zhu, J1
Janin, A1
Daniel, MT1
Gourmel, B1
Degos, L1
Dombret, H1
De Thé, H1
Mortensen, BT1
Jensen, PO1
Helledie, N1
Iversen, PO1
Ralfkiaer, E1
Larsen, JK1
Madsen, MT1
Kim, KT1
Yeo, EJ1
Choi, H1
Park, SC1
Vassiliadis, S1
Guilbert, LJ1
Moens, U1
Bang, BE1
Aarbakke, J1
Tanizawa, A1
Kubota, M1
Hashimoto, H1
Shimizu, T1
Takimoto, T1
Kitoh, T1
Akiyama, Y1
Mikawa, H1
Boss, GR1

Other Studies

8 other studies available for theophylline and Leukemia, Promyelocytic, Acute

ArticleYear
Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis.
    Cell death & disease, 2013, Feb-28, Volume: 4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Antibiotics, Antineoplastic; Apoptosis; bcl-Associated Death P

2013
In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia.
    The Journal of experimental medicine, 2002, Nov-18, Volume: 196, Issue:10

    Topics: Animals; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Division; Cyclic AMP; Leukemia, Pr

2002
Changing bone marrow micro-environment during development of acute myeloid leukaemia in rats.
    British journal of haematology, 1998, Volume: 102, Issue:2

    Topics: Acute Disease; Animals; Body Weight; Bone Marrow; Cell Cycle; Hematopoiesis; Hydrogen-Ion Concentrat

1998
The effect of pyrimidine nucleosides on adenosine-induced apoptosis in HL-60 cells.
    Journal of cancer research and clinical oncology, 1998, Volume: 124, Issue:9

    Topics: Adenosine; Apoptosis; Blotting, Western; Dipyridamole; DNA Fragmentation; DNA, Neoplasm; Electrophor

1998
Immune interferon induces early and late events in differentiation of HL-60 cells that are part of the same maturation program.
    Experimental hematology, 1991, Volume: 19, Issue:4

    Topics: Cell Line; Gene Expression Regulation; HLA-DR Antigens; Interferon-gamma; Leukemia, Promyelocytic, A

1991
Physiological cyclic AMP stimulation and oncogene mRNA levels in HL-60 cells.
    Life sciences, 1990, Volume: 47, Issue:17

    Topics: Base Sequence; Cyclic AMP; Gene Expression; Humans; Isoproterenol; Leukemia, Promyelocytic, Acute; M

1990
VP-16-induced nucleotide pool changes and poly(ADP-ribose) synthesis: the role of VP-16 in interphase death.
    Experimental cell research, 1989, Volume: 185, Issue:1

    Topics: Benzamides; Cell Line; Cell Survival; DNA Damage; Etoposide; Humans; Interphase; Leukemia, Promyeloc

1989
cGMP-induced differentiation of the promyelocytic cell line HL-60.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:18

    Topics: Cell Differentiation; Cell Line; Cyclic AMP; Cyclic GMP; Flow Cytometry; Humans; Kinetics; Leukemia,

1989