Page last updated: 2024-10-22

theophylline and Leukemia, Myeloid, Acute

theophylline has been researched along with Leukemia, Myeloid, Acute in 7 studies

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research Excerpts

ExcerptRelevanceReference
"Acute myelogenous leukemia (AML) patients (24 consecutive patients, median age 71 years, 17 high-risk disease) were treated with all-trans retinoic acid, theophylline and valproic acid."7.75A subset of patients with high-risk acute myelogenous leukemia shows improved peripheral blood cell counts when treated with the combination of valproic acid, theophylline and all-trans retinoic acid. ( Bruserud, O; Corbascio, M; Gjertsen, BT; Lassalle, P; Ryningen, A; Stapnes, C, 2009)
"Acute myelogenous leukemia (AML) patients (24 consecutive patients, median age 71 years, 17 high-risk disease) were treated with all-trans retinoic acid, theophylline and valproic acid."3.75A subset of patients with high-risk acute myelogenous leukemia shows improved peripheral blood cell counts when treated with the combination of valproic acid, theophylline and all-trans retinoic acid. ( Bruserud, O; Corbascio, M; Gjertsen, BT; Lassalle, P; Ryningen, A; Stapnes, C, 2009)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ryningen, A1
Stapnes, C1
Lassalle, P1
Corbascio, M1
Gjertsen, BT2
Bruserud, O2
Fredly, H1
Reikvam, H1
Peracchi, M1
Maiolo, AT1
Lombardi, L1
Catena, FB1
Polli, EE1
Kindzel'skiĭ, AL1
Gaĭdukova, SN1
Chaplinski, TJ2
Niedel, JE1
Bennett, TE1
Studzinski, GP1
Bhandal, AK1
Brelvi, ZS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Differentiation Induction Therapy for Acute Myelogenous Leukemia[NCT00175812]Phase 1/Phase 224 participants (Actual)Interventional2004-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for theophylline and Leukemia, Myeloid, Acute

ArticleYear
Disease-stabilizing treatment with all-trans retinoic acid and valproic acid in acute myeloid leukemia: serum hsp70 and hsp90 levels and serum cytokine profiles are determined by the disease, patient age, and anti-leukemic treatment.
    American journal of hematology, 2012, Volume: 87, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarab

2012

Other Studies

6 other studies available for theophylline and Leukemia, Myeloid, Acute

ArticleYear
A subset of patients with high-risk acute myelogenous leukemia shows improved peripheral blood cell counts when treated with the combination of valproic acid, theophylline and all-trans retinoic acid.
    Leukemia research, 2009, Volume: 33, Issue:6

    Topics: Aged; Aged, 80 and over; Blood Cell Count; Drug Therapy, Combination; Female; Humans; Leukemia, Myel

2009
Patterns of cyclic nucleotides in normal and leukaemic human leucocytes.
    British journal of cancer, 1980, Volume: 41, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Carbachol; Cyclic AMP; Cyclic GMP; Guanylate

1980
[The diagnostic significance of a surface modification in the T-lymphocytes in acute leukemia].
    Likars'ka sprava, 1993, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Immunity, Cellular; Leukemia,

1993
Cyclic AMP levels and cellular kinetics during maturation of human promyelocytic leukemia cells.
    Journal of leukocyte biology, 1986, Volume: 39, Issue:3

    Topics: Bucladesine; Cell Cycle; Cell Division; Cell Line; Cyclic AMP; Dimethyl Sulfoxide; Dinoprostone; Hum

1986
Study of differentiation of fresh myeloid leukemic cells by physiologic agents that induce a human promyelocytic leukemic line (HL-60) to differentiate.
    Leukemia research, 1986, Volume: 10, Issue:6

    Topics: Bucladesine; Cell Cycle; Cell Differentiation; Cell Line; Cells, Cultured; Cytarabine; Dinoprostone;

1986
Cell cycle sensitivity of HL-60 cells to the differentiation-inducing effects of 1-alpha,25-dihydroxyvitamin D3.
    Cancer research, 1985, Volume: 45, Issue:8

    Topics: Calcitriol; Cell Cycle; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Humans; L

1985