Page last updated: 2024-10-22

theophylline and Ischemia

theophylline has been researched along with Ischemia in 46 studies

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"The sum of pain scores (accumulation of VAS scores) was attenuated by theophylline, 691 [200-1550 (median and 25-75% percentiles)], compared with placebo, 1231 (545-1675), P < 0."9.11Experimentally induced ischaemic pain in healthy humans is attenuated by the adenosine receptor antagonist theophylline. ( Karelov, A; Segerdahl, M, 2004)
"To study the hypothesis that endogenous adenosine is a mediator of the ischaemic pain sensation, the effect of the adenosine receptor blocker theophylline (5."9.06Theophylline decreases pain in the ischaemic forearm test. ( Jonzon, B; Kaijser, L; Sylvén, C, 1989)
"The TEA-Stroke trial (The Theophylline in Acute Ischemic Stroke) was an investigator-initiated 2-center, proof-of-concept, phase II clinical study with a randomized, double-blinded, placebo-controlled design."7.96Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial. ( Andersen, G; Bach, FW; Eskildsen, HW; Hansen, MB; Hjort, N; Johansen, MB; Mikkelsen, IK; Modrau, B; Mouridsen, K; Nielsen, A; Povlsen, JP; Yavarian, Y; Østergaard, L, 2020)
"Ischemia was induced for 1 h in both eyes by elevation of intraocular pressure above systolic arterial pressure."5.29Post-ischemic hyperemia in the cat retina: the effects of adenosine receptor blockade. ( Roth, S, 1995)
"The sum of pain scores (accumulation of VAS scores) was attenuated by theophylline, 691 [200-1550 (median and 25-75% percentiles)], compared with placebo, 1231 (545-1675), P < 0."5.11Experimentally induced ischaemic pain in healthy humans is attenuated by the adenosine receptor antagonist theophylline. ( Karelov, A; Segerdahl, M, 2004)
"To study the hypothesis that endogenous adenosine is a mediator of the ischaemic pain sensation, the effect of the adenosine receptor blocker theophylline (5."5.06Theophylline decreases pain in the ischaemic forearm test. ( Jonzon, B; Kaijser, L; Sylvén, C, 1989)
"The TEA-Stroke trial (The Theophylline in Acute Ischemic Stroke) was an investigator-initiated 2-center, proof-of-concept, phase II clinical study with a randomized, double-blinded, placebo-controlled design."3.96Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial. ( Andersen, G; Bach, FW; Eskildsen, HW; Hansen, MB; Hjort, N; Johansen, MB; Mikkelsen, IK; Modrau, B; Mouridsen, K; Nielsen, A; Povlsen, JP; Yavarian, Y; Østergaard, L, 2020)
"To evaluate the early therapeutic alternatives such as bosentan, an endothelin receptor blocker, theophylline, an adenosin receptor blocker, and a nonselective phosphodiesterase enzyme inhibitor, zinc protoporphyrin (ZnPP), a heme oxygenase 1 inhibitor, for the therapy of ischemic priapism in the rat models."3.79Second pathways in the pathophysiology of ischemic priapism and treatment alternatives. ( Firdolas, F; Karakeci, A; Ogras, MS; Orhan, I; Ozan, T; Unus, I, 2013)
" In additional experimental groups, 8 sulfophenyl-theophylline (SPT, 10 mg/kg), an adenosine receptor inhibitor, was intravenously injected before the 40 min myocardial ischemia (SPT, MPC + SPT and RPC + SPT groups, respectively)."3.70Renal ischemia/reperfusion remotely improves myocardial energy metabolism during myocardial ischemia via adenosine receptors in rabbits: effects of "remote preconditioning". ( Inubushi, T; Kinoshita, M; Mitsunami, K; Morikawa, S; Nakae, I; Takaoka, A; Yabe, T, 1999)
"This study was designed to determine, through the measurement of oxygen consumption (QO2), whether pretreatment and posttreatment with theophylline, verapamil, and mannitol provide protection from damage in the cortex and medulla of rat kidneys subjected to 60 and 120 minutes of ischemia."3.68Effects of theophylline, verapamil, and mannitol on oxygen consumption of ischemic rat kidneys. ( Homma, S; Kuramochi, G, 1993)
"The effect of adenosine (ADO) on the recovery of cellular adenine nucleotides (AN) was evaluated in the cultured cells deprived of oxygen and substrates (ischemia) and in nonischemic cells (control)."3.68Roles of adenosine and theophylline on the recovery of adenine nucleotides in postischemic cultured renal tubular cells. ( Cadnapaphornchai, P; Golembieski, A; Kellner, D; McDonald, FD, 1991)
"Patients with cardiac Syndrome X are hypersensitive to potential pain stimuli, including adenosine."2.69Analgesic effects of adenosine in syndrome X are counteracted by theophylline: a double-blind placebo-controlled study. ( Eriksson, BE; Sadigh, B; Svedenhag, J; Sylvén, C, 2000)
"Aminophylline has been shown to reduce severe renal dysfunction in neonates after perinatal asphyxia."1.62Aminophylline for renal protection in neonatal hypoxic-ischemic encephalopathy in the era of therapeutic hypothermia. ( Cho, SH; Chock, VY; Frymoyer, A, 2021)
"Ischemia was induced by active hypoperfusion of the circumflex coronary artery territory."1.33How to distinguish between ischemic and nonischemic postsystolic thickening: a strain rate imaging study. ( Bijnens, B; Broscheit, JA; Claus, P; Ertl, G; Strotmann, JM; Sutherland, GR; Voelker, W; Weidemann, F, 2006)
"Brief ischemia was reported to protect various cells against injury induced by subsequent ischemia-reperfusion, and this phenomenon is known as ischemic preconditioning."1.32Histological protection against ischemia-reperfusion injury by early ischemic preconditioning in rat retina. ( Ishii, K; Kuwagata, M; Nakahara, T; Saito, M; Sakamoto, K; Yonoki, Y, 2004)
"Adenosine appears to be a crucial effector in IPC."1.31The liver protective effect of ischemic preconditioning may be mediated by adenosine. ( Delbro, D; Friman, S; Gustafsson, B; Nilsson, B; Wallin, M, 2000)
"Ischemia was induced for 1 h in both eyes by elevation of intraocular pressure above systolic arterial pressure."1.29Post-ischemic hyperemia in the cat retina: the effects of adenosine receptor blockade. ( Roth, S, 1995)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199023 (50.00)18.7374
1990's10 (21.74)18.2507
2000's9 (19.57)29.6817
2010's2 (4.35)24.3611
2020's2 (4.35)2.80

Authors

AuthorsStudies
Chock, VY1
Cho, SH1
Frymoyer, A1
Modrau, B1
Andersen, G1
Mikkelsen, IK1
Nielsen, A1
Hansen, MB1
Johansen, MB1
Eskildsen, HW1
Povlsen, JP1
Yavarian, Y1
Mouridsen, K1
Østergaard, L1
Bach, FW1
Hjort, N1
Karakeci, A1
Firdolas, F1
Ozan, T1
Unus, I1
Ogras, MS1
Orhan, I1
Johnson, NP1
Lance Gould, K1
Segerdahl, M1
Karelov, A1
Sakamoto, K2
Yonoki, Y1
Kuwagata, M2
Saito, M1
Nakahara, T2
Ishii, K2
Genescà, M1
Sola, A1
Azuara, D1
De Oca, J1
Hotter, G1
Weidemann, F1
Broscheit, JA1
Bijnens, B1
Claus, P1
Sutherland, GR1
Voelker, W1
Ertl, G1
Strotmann, JM1
Creutzig, A1
Dau, D1
Alexander, K1
Osborn, JL1
Hoversten, LG1
DiBona, GF1
Roth, S2
Takeyoshi, I3
Kokudo, Y2
Zhang, S2
Nakamura, K2
Ikoma, A2
Suzuki, T1
Zhu, Y2
Todo, S3
Kuramochi, G1
Homma, S1
Starzl, TE1
Wakabayashi, H1
Maeba, T1
Maeta, H1
Murase, N1
Ostwald, P1
Park, SS1
Toledano, AY1
Pell, TJ1
Baxter, GF1
Yellon, DM1
Drew, GM1
Takaoka, A1
Nakae, I1
Mitsunami, K1
Yabe, T1
Morikawa, S1
Inubushi, T1
Kinoshita, M1
Eriksson, BE1
Sadigh, B1
Svedenhag, J1
Sylvén, C2
Nilsson, B1
Friman, S1
Wallin, M1
Gustafsson, B1
Delbro, D1
Sugino, H1
Shimada, H1
Tsuchimoto, K1
Liem, DA1
Verdouw, PD1
Ploeg, H1
Kazim, S1
Duncker, DJ1
Yoshikawa, K1
Adachi, K1
Halprin, KM1
Levine, V1
Ahlström, P1
Thalmann, I1
Thalmann, R1
Ise, I1
Haddy, FJ1
Sakai, K1
Akima, M1
Nabata, H1
Osswald, H1
Schmitz, HJ1
Kemper, R1
Lebedev, AA1
Dubishchev, AV1
Gafner, F1
Cadnapaphornchai, P1
Kellner, D1
Golembieski, A1
McDonald, FD1
Deray, G1
Martinez, F1
Cacoub, P1
Baumelou, B1
Baumelou, A1
Jacobs, C1
Jonzon, B1
Kaijser, L1
Grossmann, K1
Knischka, A1
Rao, KR1
Mahesh, SV1
Rao, PN1
Sollevi, A1
Hellman, B1
Idahl, LA1
Hansteen, V1
Lorentsen, E1
Wollenberger, A1
Kleitke, B1
Heiss, WD1
Davis, E1
Rozov, H1
Vahlensieck, W1
Förster, KH1
Müller, KH1
Serradimigni, A1
Bory, M1
Poggi, L1
Audier, M1
Stoner, HB1
Little, RA1
Skalkeas, G1
Balas, P1
Katsogianis, A1
Bakoulas, G1
Karagianakos, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pharmacokinetics (PK) and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia[NCT05295784]Phase 118 participants (Anticipated)Interventional2024-06-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for theophylline and Ischemia

ArticleYear
Bioassay and pharmacologic evaluation of the adenosine hypothesis.
    Advances in experimental medicine and biology, 1977, Volume: 78

    Topics: Adenosine; Adenosine Monophosphate; Animals; Biological Assay; Coronary Circulation; Hyperemia; Hypo

1977
Cardiovascular effects of adenosine in man; possible clinical implications.
    Progress in neurobiology, 1986, Volume: 27, Issue:4

    Topics: Adenosine; Cardiovascular Diseases; Cardiovascular System; Humans; Hypoxia; Ischemia; Purines; Recep

1986

Trials

3 trials available for theophylline and Ischemia

ArticleYear
Experimentally induced ischaemic pain in healthy humans is attenuated by the adenosine receptor antagonist theophylline.
    Acta physiologica Scandinavica, 2004, Volume: 180, Issue:3

    Topics: Adult; Blood Pressure; Double-Blind Method; Female; Humans; Infusions, Intravenous; Ischemia; Male;

2004
Analgesic effects of adenosine in syndrome X are counteracted by theophylline: a double-blind placebo-controlled study.
    Clinical science (London, England : 1979), 2000, Volume: 98, Issue:1

    Topics: Adenosine; Analgesics; Analysis of Variance; Cross-Over Studies; Double-Blind Method; Exercise Test;

2000
Theophylline decreases pain in the ischaemic forearm test.
    Cardiovascular research, 1989, Volume: 23, Issue:9

    Topics: Adult; Blood Flow Velocity; Clinical Trials as Topic; Double-Blind Method; Forearm; Humans; Ischemia

1989

Other Studies

41 other studies available for theophylline and Ischemia

ArticleYear
Aminophylline for renal protection in neonatal hypoxic-ischemic encephalopathy in the era of therapeutic hypothermia.
    Pediatric research, 2021, Volume: 89, Issue:4

    Topics: Acute Kidney Injury; Aminophylline; Asphyxia Neonatorum; Biomarkers; Creatinine; Female; Humans; Hyp

2021
Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial.
    Stroke, 2020, Volume: 51, Issue:7

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Fibrinolytic Agents; Humans; Ischemia; Male; Middle

2020
Second pathways in the pathophysiology of ischemic priapism and treatment alternatives.
    Urology, 2013, Volume: 82, Issue:3

    Topics: Adenosine Deaminase; Animals; Antihypertensive Agents; Apoptosis; Bosentan; Endothelin Receptor Anta

2013
Dipyridamole reversal using theophylline during aminophylline shortage.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2011, Volume: 18, Issue:6

    Topics: Aminophylline; Dipyridamole; Drug Substitution; Humans; Ischemia; Theophylline; Therapeutic Equivale

2011
Histological protection against ischemia-reperfusion injury by early ischemic preconditioning in rat retina.
    Brain research, 2004, Jul-23, Volume: 1015, Issue:1-2

    Topics: Adrenergic alpha-Antagonists; Animals; Enzyme Inhibitors; Intraocular Pressure; Ischemia; Ischemic P

2004
Apoptosis inhibition during preservation by fructose-1,6-diphosphate and theophylline in rat intestinal transplantation.
    Critical care medicine, 2005, Volume: 33, Issue:4

    Topics: Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Bacterial Translocation; Disease Models, Anim

2005
How to distinguish between ischemic and nonischemic postsystolic thickening: a strain rate imaging study.
    Ultrasound in medicine & biology, 2006, Volume: 32, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Aortic Valve; Aortic Valve Insufficiency; Blood Pressure; Card

2006
[Transcutaneous oxygen pressure during intra-arterial infusions].
    VASA. Zeitschrift fur Gefasskrankheiten, 1984, Volume: 13, Issue:3

    Topics: Adult; Aged; Arterial Occlusive Diseases; Female; Humans; Infusions, Intra-Arterial; Ischemia; Leg;

1984
Impaired blood flow autoregulation in nonfiltering kidneys: effects of theophylline administration.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1983, Volume: 174, Issue:3

    Topics: Adenosine; Animals; Dogs; Homeostasis; Ischemia; Kidney; Renal Circulation; Theophylline; Vascular R

1983
Post-ischemic hyperemia in the cat retina: the effects of adenosine receptor blockade.
    Current eye research, 1995, Volume: 14, Issue:4

    Topics: Adenosine; Animals; Blood Flow Velocity; Cats; Choroid; Hemodynamics; Hyperemia; Ischemia; Microsphe

1995
Susceptibility to ischemia: the large bowel versus the small bowel.
    Transplantation proceedings, 1994, Volume: 26, Issue:3

    Topics: Animals; Dogs; Electrophysiology; Female; Glucose; Intestinal Mucosa; Intestine, Large; Intestine, S

1994
Effects of theophylline, verapamil, and mannitol on oxygen consumption of ischemic rat kidneys.
    Nihon Jinzo Gakkai shi, 1993, Volume: 35, Issue:8

    Topics: Animals; Ischemia; Kidney; Male; Mannitol; Oxygen Consumption; Rats; Rats, Wistar; Theophylline; Ver

1993
Effect of ischemia on the canine large bowel: a comparison with the small intestine.
    The Journal of surgical research, 1996, Volume: 62, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cold Temperature; Colon; Dextrans; Dogs; Electrophysiology; Energy

1996
Effect of glucose introduction to the lumen during cold ischemia in rat small bowel.
    Transplantation proceedings, 1996, Volume: 28, Issue:5

    Topics: Animals; Cold Temperature; Glucose; Intestinal Mucosa; Intestine, Small; Ischemia; Male; Muscle, Smo

1996
Adenosine receptor blockade and nitric oxide synthase inhibition in the retina: impact upon post-ischemic hyperemia and the electroretinogram.
    Vision research, 1997, Volume: 37, Issue:24

    Topics: Analysis of Variance; Animals; Arginine; Cats; Choroid; Electroretinography; Hyperemia; Ischemia; Mi

1997
Renal ischemia preconditions myocardium: role of adenosine receptors and ATP-sensitive potassium channels.
    The American journal of physiology, 1998, Volume: 275, Issue:5

    Topics: Animals; Ischemia; Ischemic Preconditioning, Myocardial; Kidney; Potassium Channels; Purinergic P1 R

1998
Renal ischemia/reperfusion remotely improves myocardial energy metabolism during myocardial ischemia via adenosine receptors in rabbits: effects of "remote preconditioning".
    Journal of the American College of Cardiology, 1999, Volume: 33, Issue:2

    Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Hydrogen-Ion Concentration; Infusions, Intraveno

1999
The liver protective effect of ischemic preconditioning may be mediated by adenosine.
    Transplant international : official journal of the European Society for Organ Transplantation, 2000, Volume: 13 Suppl 1

    Topics: Adenosine; Alanine Transaminase; Animals; Ischemia; Ischemic Preconditioning; Liver; Liver Circulati

2000
Late preconditioning in rat retina: involvement of adenosine and ATP-sensitive K(+) channel.
    European journal of pharmacology, 2001, Apr-20, Volume: 418, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Cell Size; Decanoic Acids; Hydroxy Acids; Ion Channel Gating; Ische

2001
Role of adenosine in renal protection induced by a brief episode of ischemic preconditioning in rats.
    Japanese journal of pharmacology, 2001, Volume: 87, Issue:2

    Topics: Adenosine; Animals; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Ischemia; Ischemic Preco

2001
Sites of action of adenosine in interorgan preconditioning of the heart.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:1

    Topics: Adenosine; Animals; Blood Pressure; Coronary Vessels; Ganglionic Blockers; Heart Rate; Hexamethonium

2002
Cyclic AMP in skin: effects of acute ischaemia.
    The British journal of dermatology, 1975, Volume: 92, Issue:3

    Topics: Animals; Cyclic AMP; Epinephrine; Freezing; Ischemia; Propranolol; Skin; Swine; Theophylline; Time F

1975
Cyclic AMP and adenylate cyclase in the inner ear.
    The Laryngoscope, 1975, Volume: 85, Issue:7

    Topics: Action Potentials; Adenosine Triphosphatases; Adenylyl Cyclases; Animals; Barbiturates; Brain; Bucla

1975
A possible purinergic mechanism for reactive ischemia in isolated, cross-circulated rat kidney.
    Japanese journal of pharmacology, 1979, Volume: 29, Issue:2

    Topics: Animals; Cross Circulation; In Vitro Techniques; Ischemia; Kidney; Male; Muscle, Smooth, Vascular; P

1979
Tissue content of adenosine, inosine and hypoxanthine in the rat kidney after ischemia and postischemic recirculation.
    Pflugers Archiv : European journal of physiology, 1977, Oct-19, Volume: 371, Issue:1-2

    Topics: Adenosine; Animals; Hypoxanthines; Inosine; Ischemia; Kidney; Rats; Regional Blood Flow; Theophyllin

1977
[Kidney function and mitochondrial metabolism in excluded renal blood flow against a background of diuretic action].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1978, Volume: 64, Issue:3

    Topics: Animals; Diuretics; Drug Combinations; Ethacrynic Acid; Female; Furosemide; Ischemia; Kidney; Kidney

1978
[Experiences with drug therapy in association with ischaemic vascular disease of the fundus oculi (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1977, Volume: 170, Issue:5

    Topics: Adult; Aged; Drug Combinations; Fundus Oculi; Glaucoma; Heptaminol; Humans; Ischemia; Middle Aged; N

1977
Roles of adenosine and theophylline on the recovery of adenine nucleotides in postischemic cultured renal tubular cells.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, C

1991
A role for adenosine calcium and ischemia in radiocontrast-induced intrarenal vasoconstriction.
    American journal of nephrology, 1990, Volume: 10, Issue:4

    Topics: Acute Kidney Injury; Adenosine; Animals; Biological Transport, Active; Calcium; Contrast Media; Diat

1990
[Intra-arterial therapy of arterial occlusive diseases of the extremities].
    Zeitschrift fur arztliche Fortbildung, 1987, Volume: 81, Issue:17

    Topics: Actihaemyl; Adenosine Triphosphate; Anti-Bacterial Agents; Arterial Occlusive Diseases; Drug Therapy

1987
Massive perfusion with vasodilators for ischaemic retinopathy and optic nerve diseases--a new approach.
    Indian journal of ophthalmology, 1987, Volume: 35, Issue:5-6

    Topics: Humans; Ischemia; Optic Nerve Diseases; Perfusion; Retina; Theophylline; Xanthinol Niacinate

1987
[Control of ATP levels in stimulated pancreatic B-cells].
    Acta diabetologica latina, 1969, Volume: 6 Suppl 1

    Topics: Adenosine Triphosphate; Animals; Butyrates; Carbutamide; Cyclic AMP; Diazoxide; Epinephrine; Glucago

1969
Vasodilator drugs in the treatment of peripheral arterial insufficiency.
    Acta medica Scandinavica. Supplementum, 1974, Volume: 556

    Topics: Adult; Aged; Aminophylline; Angiotensin II; Arteriosclerosis Obliterans; Drug Evaluation; Female; Fo

1974
Ribonucleic acid and protein synthesis in rat heart mitochondria isolated after aortic constriction, strenuous physical exercise, total myocardial ischemia, and theophylline treatment.
    Recent advances in studies on cardiac structure and metabolism, 1973, Volume: 3

    Topics: Animals; Cardiomegaly; Cell Nucleus; Cell-Free System; Chloramphenicol; Coronary Circulation; Cyclic

1973
[Drug-induced reaction patterns of regional cerebral blood flow (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Volume: 99, Issue:8

    Topics: Administration, Oral; Benzamides; Benzoates; Blood Pressure; Brain; Cerebrovascular Circulation; Cer

1974
The effects of xanthinol nicotinate on the small blood vessels.
    Bibliotheca anatomica, 1973, Volume: 11

    Topics: Amino Alcohols; Arteriosclerosis; Blood Viscosity; Conjunctiva; Diabetic Angiopathies; Erythrocyte A

1973
[Preservation of kidney transplants].
    Langenbecks Archiv fur Chirurgie, 1968, Volume: 322

    Topics: Adrenal Cortex Hormones; Animals; Bicarbonates; Buffers; Coumarins; Dogs; Humans; Hyperbaric Oxygena

1968
[Treatment problems in acute circulation disorders of the inner ear using low molecular dextrans].
    HNO, 1972, Volume: 20, Issue:7

    Topics: Acute Disease; Blood Coagulation; Blood Coagulation Disorders; Blood Platelets; Deafness; Dextrans;

1972
[Medical treatment of acute arterial obliteration in the limbs].
    Revue de l'atherosclerose et des arteriopathies peripheriques, 1968, Volume: 10, Issue:2

    Topics: Acute Disease; Adult; Aged; Arteriosclerosis Obliterans; Drug Synergism; Female; Fibrinolytic Agents

1968
Studies on the mechanism of shock. The effect of cocaine and theophylline on the temperature response to injury in the cold-acclimated rat.
    British journal of experimental pathology, 1969, Volume: 50, Issue:2

    Topics: Acclimatization; Animals; Body Temperature; Body Temperature Regulation; Catecholamines; Cocaine; Co

1969
A new approach to the treatment of ischemic conditions of the extremities: continous intraarterial infusion therapy.
    Angiology, 1969, Volume: 20, Issue:3

    Topics: Amputation, Surgical; Arteries; Blood Circulation; Body Temperature; Brachial Artery; Dextrans; Fema

1969