theophylline has been researched along with Idiopathic Parkinson Disease in 15 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "theophylline were compared before and after a 4-week period of oral treatment with ropinirole (2 mg t." | 2.69 | Lack of pharmacokinetic interaction between ropinirole and theophylline in patients with Parkinson's disease. ( Brefel-Courbon, C; Eagle, S; Fitzpatrick, K; Rascol, O; Taylor, A; Thalamas, C, 1999) |
| "This tremor is normally recordable at a stable frequency of 8-10 Hz, though this can be influenced by age, the amplitude can vary substantially." | 2.39 | [Most frequent causes for hand tremor in clinical practice]. ( Málly, J, 1995) |
| "Caffeine has been considered a neuroprotective agent against Parkinson's disease (PD)." | 1.48 | Biomarker repurposing: Therapeutic drug monitoring of serum theophylline offers a potential diagnostic biomarker of Parkinson's disease. ( Ishii, R; Kasai, T; Kosaka, T; Mizuno, T; Ohmichi, T; Shikata, K; Shinomoto, M; Tatebe, H; Tokuda, T, 2018) |
| "Caffeine half-life was also estimated from salivary concentrations of caffeine at 2 and 5 h post dose." | 1.31 | Parkinson's disease and CYP1A2 activity. ( Forsyth, JT; Grünewald, RA; Lennard, MS; Rostami-Hodjegan, A; Sagar, HJ; Tucker, GT, 2000) |
| " In the therapeutic use of theophylline monitoring of the serum theophylline concentration is generally advised because of the elsewhere reported variability in the biological half-life of the compound." | 1.26 | Pharmacokinetics of theophylline in ten elderly patients. ( Jakobsen, P; Magnussen, I; Nielsen-Kudsk, F, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (26.67) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 4 (26.67) | 2.80 |
| Authors | Studies |
|---|---|
| Matsumura, N | 1 |
| Aoyama, K | 1 |
| Maclagan, LC | 1 |
| Visanji, NP | 1 |
| Cheng, Y | 1 |
| Tadrous, M | 1 |
| Lacoste, AMB | 1 |
| Kalia, LV | 1 |
| Bronskill, SE | 1 |
| Marras, C | 1 |
| Rohilla, S | 1 |
| Bansal, R | 1 |
| Chauhan, P | 1 |
| Kachler, S | 1 |
| Klotz, KN | 1 |
| Janitschke, D | 1 |
| Lauer, AA | 1 |
| Bachmann, CM | 1 |
| Grimm, HS | 1 |
| Hartmann, T | 1 |
| Grimm, MOW | 1 |
| Ohmichi, T | 1 |
| Kasai, T | 1 |
| Kosaka, T | 1 |
| Shikata, K | 1 |
| Tatebe, H | 1 |
| Ishii, R | 1 |
| Shinomoto, M | 1 |
| Mizuno, T | 1 |
| Tokuda, T | 1 |
| Málly, J | 2 |
| Stone, TW | 1 |
| Kostic, VS | 1 |
| Svetel, M | 1 |
| Sternic, N | 1 |
| Dragasevic, N | 1 |
| Przedborski, S | 1 |
| Thalamas, C | 1 |
| Taylor, A | 1 |
| Brefel-Courbon, C | 1 |
| Eagle, S | 1 |
| Fitzpatrick, K | 1 |
| Rascol, O | 1 |
| Forsyth, JT | 1 |
| Grünewald, RA | 1 |
| Rostami-Hodjegan, A | 1 |
| Lennard, MS | 1 |
| Sagar, HJ | 1 |
| Tucker, GT | 1 |
| Kanda, A | 1 |
| Ebihara, S | 1 |
| Arai, H | 1 |
| Takeda, A | 1 |
| Sasaki, H | 1 |
| Nielsen-Kudsk, F | 1 |
| Magnussen, I | 1 |
| Jakobsen, P | 1 |
| Nelson, SR | 1 |
| Walaszek, EJ | 1 |
| Hidaka, H | 1 |
| Shibuya, M | 1 |
| Diemath, HE | 1 |
| Enge, S | 1 |
| Lechner, H | 1 |
4 reviews available for theophylline and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Glutathione-Mediated Neuroprotective Effect of Purine Derivatives.
Topics: Adenosine A2 Receptor Antagonists; Alzheimer Disease; Brain; Caffeine; Cysteine; Excitatory Amino Ac | 2023 |
Methylxanthines and Neurodegenerative Diseases: An Update.
Topics: Alzheimer Disease; Animals; Caffeine; Coffee; Humans; Multiple Sclerosis; Neurodegenerative Diseases | 2021 |
[Most frequent causes for hand tremor in clinical practice].
Topics: Aged; Aged, 80 and over; Aging; Female; Hand; Humans; Hypokinesia; Male; Parkinson Disease; Posture; | 1995 |
Pharmacology of the central nervous system.
Topics: Abnormalities, Drug-Induced; Acetylcholine; Adrenocorticotropic Hormone; Amphetamine; Anger; Angiote | 1968 |
2 trials available for theophylline and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
The effect of theophylline on parkinsonian symptoms.
Topics: Administration, Oral; Aged; Aged, 80 and over; Delayed-Action Preparations; Disability Evaluation; F | 1994 |
Lack of pharmacokinetic interaction between ropinirole and theophylline in patients with Parkinson's disease.
Topics: Administration, Oral; Aged; Antiparkinson Agents; Cytochrome P-450 CYP1A2; Dopamine Agonists; Drug I | 1999 |
9 other studies available for theophylline and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Identifying drugs with disease-modifying potential in Parkinson's disease using artificial intelligence and pharmacoepidemiology.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Artificial Intelligence; Case-Control Studies; Dexame | 2020 |
A New Series of 1,3-Dimethylxanthine Based Adenosine A
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Molecular Docking Simulation; Parkinson Disea | 2021 |
Biomarker repurposing: Therapeutic drug monitoring of serum theophylline offers a potential diagnostic biomarker of Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Caffeine; Central Nervous System Stimulants; Female; Hum | 2018 |
Theophylline increases "on" time in advanced parkinsonian patients.
Topics: Adult; Humans; Middle Aged; Parkinson Disease; Theophylline; Time Factors | 1999 |
Parkinson's disease and CYP1A2 activity.
Topics: Adult; Aged; Aged, 80 and over; Caffeine; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged | 2000 |
Parkinson's disease and impaired chemosensitivity to hypoxia.
Topics: Caffeine; Humans; Parkinson Disease; Phosphodiesterase Inhibitors; Respiration; Theophylline | 2000 |
Pharmacokinetics of theophylline in ten elderly patients.
Topics: Age Factors; Aged; Female; Half-Life; Hemiplegia; Humans; Injections, Intravenous; Male; Middle Aged | 1978 |
A new assay of cyclic nucleotide phosphodiesterase; its application to human serum.
Topics: Adult; Animals; Brain; Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Glioblastoma; Humans; H | 1974 |
EEG depth leads during stereotaxic brain surgery. A report on 117 cases (5 target points, effects of 13 different drugs).
Topics: Amides; Amygdala; Antimetabolites; Asparagine; Benzoates; Brain; Brain Diseases; Cerebrovascular Cir | 1970 |