theophylline has been researched along with Hypoxia-Ischemia, Brain in 7 studies
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Birth weight was a significant predictor of theophylline clearance and volume of distribution (p < 0." | 3.96 | Theophylline dosing and pharmacokinetics for renal protection in neonates with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia. ( Chock, VY; Christians, U; Drover, DR; Frymoyer, A; Klawitter, J; Van Meurs, KP, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Starr, MC | 1 |
| Charlton, JR | 1 |
| Guillet, R | 1 |
| Reidy, K | 1 |
| Tipple, TE | 1 |
| Jetton, JG | 1 |
| Kent, AL | 1 |
| Abitbol, CL | 1 |
| Ambalavanan, N | 1 |
| Mhanna, MJ | 1 |
| Askenazi, DJ | 1 |
| Selewski, DT | 1 |
| Harer, MW | 1 |
| Frymoyer, A | 1 |
| Van Meurs, KP | 1 |
| Drover, DR | 1 |
| Klawitter, J | 1 |
| Christians, U | 1 |
| Chock, VY | 1 |
| Gervitz, LM | 3 |
| Nalbant, D | 1 |
| Williams, SC | 1 |
| Fowler, JC | 3 |
| Lutherer, LO | 2 |
| Hamilton, ME | 1 |
| Coelho, JE | 1 |
| Rebola, N | 1 |
| Fragata, I | 1 |
| Ribeiro, JA | 1 |
| de Mendonça, A | 1 |
| Cunha, RA | 1 |
| Aketa, S | 1 |
| Nakase, H | 1 |
| Kamada, Y | 1 |
| Hiramatsu, K | 1 |
| Sakaki, T | 1 |
| Davies, DG | 1 |
| Pirch, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics (PK) and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia[NCT05295784] | Phase 1 | 18 participants (Anticipated) | Interventional | 2024-06-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for theophylline and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Advances in Neonatal Acute Kidney Injury.
Topics: Acute Kidney Injury; Biomarkers; Caffeine; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Infant, | 2021 |
6 other studies available for theophylline and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Theophylline dosing and pharmacokinetics for renal protection in neonates with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia.
Topics: Aminophylline; Birth Weight; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Hypotherm | 2020 |
Adenosine-mediated activation of Akt/protein kinase B in the rat hippocampus in vitro and in vivo.
Topics: Adenosine; Animals; Cell Death; Cerebrovascular Circulation; Hippocampus; Hypoxia-Ischemia, Brain; I | 2002 |
Lack of central effects of peripherally administered adenosine A(1) agonists on synaptic transmission in the rat hippocampus.
Topics: Adenosine; Animals; Cardiovascular Physiological Phenomena; Excitatory Postsynaptic Potentials; Hipp | 2002 |
Hypoxia-induced desensitization and internalization of adenosine A1 receptors in the rat hippocampus.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Disease Models, Animal; En | 2006 |
Chemical preconditioning with 3-nitropropionic acid in gerbil hippocampal slices: therapeutic window and the participation of adenosine receptor.
Topics: Adaptation, Physiological; Animals; Antihypertensive Agents; Excitatory Postsynaptic Potentials; Ger | 2000 |
Adenosine induces initial hypoxic-ischemic depression of synaptic transmission in the rat hippocampus in vivo.
Topics: Acid-Base Equilibrium; Adenosine; Animals; Blood Pressure; Caffeine; Carotid Artery, Common; Constri | 2001 |