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theophylline and Hypokalemia

theophylline has been researched along with Hypokalemia in 39 studies

Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Presenting a case of acute theophylline and salbutamol overdose with distributive shock."7.96Theophylline toxicity: Successful management of a patient with distributive shock secondary to drug overdose. ( Chandrasekaran, VP; Muruga, B; Parthasarathy, A, 2020)
"Metabolic and electrolyte abnormalities, including hypokalemia, hyperglycemia and lactic acidosis, are associated with theophylline overdose."7.71Lactic acidosis associated with the usual theophylline dose in a patient with asthma. ( Choi, IS; Koh, YI, 2002)
"To determine if differences in the rate of hypokalemia and hyperglycemia between victims of acute versus chronic theophylline intoxication relate to alterations in plasma catecholamine activity, we evaluated plasma catechols in three groups of patients: victims of acute theophylline intoxication (n = 10), chronic theophylline overmedication (n = 3), and healthy controls (n = 6)."7.69Hypokalemia, hyperglycemia and plasma catecholamine activity after severe theophylline intoxication. ( Shannon, M, 1994)
"We report a case of respiratory arrest in a ten-year-old asthmatic girl under beta-2-agonists and theophylline."7.67[Respiratory arrest in an asthmatic girl treated with beta-2-mimetics and theophylline. Possible role of hypokalemia in sudden death in asthmatic patients]. ( Benhamou, PH; Devoldere, C; Epelbaum, S; Kremp, O; Pautard, JC; Piussan, C, 1989)
"The frequency, severity, and time of occurrence of hypokalemia and their relationship with vomiting was studied in 40 patients with acute theophylline poisoning."7.67Hypokalemia in acute theophylline poisoning. ( Amitai, Y; Lovejoy, FH, 1988)
"A 70-year-old patient who developed ventricular tachycardia (up to several hundreds of consecutive ventricular complexes) in the presence of theophylline intoxication (29 micrograms/ml) is reported."7.67Prolonged runs of ventricular tachycardia as a complication of theophylline intoxication. Report of a case. ( Parizel, G; Siemons, LJ, 1986)
"Presenting a case of acute theophylline and salbutamol overdose with distributive shock."3.96Theophylline toxicity: Successful management of a patient with distributive shock secondary to drug overdose. ( Chandrasekaran, VP; Muruga, B; Parthasarathy, A, 2020)
"Metabolic and electrolyte abnormalities, including hypokalemia, hyperglycemia and lactic acidosis, are associated with theophylline overdose."3.71Lactic acidosis associated with the usual theophylline dose in a patient with asthma. ( Choi, IS; Koh, YI, 2002)
"Patients with measurable theophylline had a higher risk of hypokalemia, hyponatremia, hyperglycemia, hypophosphatemia, and hypomagnesemia compared with the unexposed control group."3.69Metabolic correlates of theophylline therapy: a concentration-related phenomenon. ( Flack, JM; Ryder, KW; Strickland, D; Whang, R, 1994)
"To determine if differences in the rate of hypokalemia and hyperglycemia between victims of acute versus chronic theophylline intoxication relate to alterations in plasma catecholamine activity, we evaluated plasma catechols in three groups of patients: victims of acute theophylline intoxication (n = 10), chronic theophylline overmedication (n = 3), and healthy controls (n = 6)."3.69Hypokalemia, hyperglycemia and plasma catecholamine activity after severe theophylline intoxication. ( Shannon, M, 1994)
"We report a case of respiratory arrest in a ten-year-old asthmatic girl under beta-2-agonists and theophylline."3.67[Respiratory arrest in an asthmatic girl treated with beta-2-mimetics and theophylline. Possible role of hypokalemia in sudden death in asthmatic patients]. ( Benhamou, PH; Devoldere, C; Epelbaum, S; Kremp, O; Pautard, JC; Piussan, C, 1989)
"Hypokalemia and lactic acidosis developed following correction of respiratory acidosis in a 5-year-old child who presented with respiratory failure secondary to severe asthma and treated with theophylline, inhaled albuterol, and parenteral methylprednisolone."3.67Therapy of acute bronchospasm. Complicated by lactic acidosis and hypokalemia. ( Assadi, FK, 1989)
"The frequency, severity, and time of occurrence of hypokalemia and their relationship with vomiting was studied in 40 patients with acute theophylline poisoning."3.67Hypokalemia in acute theophylline poisoning. ( Amitai, Y; Lovejoy, FH, 1988)
"A 70-year-old patient who developed ventricular tachycardia (up to several hundreds of consecutive ventricular complexes) in the presence of theophylline intoxication (29 micrograms/ml) is reported."3.67Prolonged runs of ventricular tachycardia as a complication of theophylline intoxication. Report of a case. ( Parizel, G; Siemons, LJ, 1986)
" Management of the patient's hypokalemia with moderate doses of potassium chloride resulted in hyperkalemia with associated electrocardiographic changes."3.67Management considerations in treating metabolic abnormalities associated with theophylline overdose. ( D'Angio, R; Sabatelli, F, 1987)
" In a single-blind study of 14 normal volunteers, we infused salbutamol in doses used in clinical practice and examined the effects of the addition of theophylline alone or combined with (-)-adrenaline on plasma potassium levels, heart rate and blood pressure."2.66Salbutamol induced hypokalaemia: the effect of theophylline alone and in combination with adrenaline. ( Addis, GJ; Reid, C; Reid, JL; Whitesmith, R; Whyte, KF, 1988)
"Although life-threatening events (seizures or arrhythmias) occurred at a similar rate across categories, the (theo) at which these events occurred was significantly higher in patients with acute intoxication than in those with chronic intoxication (100 vs 42 micrograms/ml; p = 0."1.28Effect of acute versus chronic intoxication on clinical features of theophylline poisoning in children. ( Lovejoy, FH; Shannon, M, 1992)
" Although the number of subjects studied is small, our data suggest that air-driven nebulised high-dose salbutamol may be safe in the treatment of severe chronic obstructive airway disease but when combined with oral theophylline, a significant fall in plasma potassium may occur."1.28Air-driven nebulised high-dose salbutamol in severe chronic obstructive airways disease: is it safe? ( Friend, JA; Lai, CK; Legge, JS, 1991)
" Toxic levels of theophylline were associated with hypokalemia, hypophosphatemia, hyperglycemia, metabolic acidosis, and hypotension in both the patient and the experimental series."1.27Theophylline toxicity and the beta-adrenergic system. ( Curtis, GP; Kearney, TE; Manoguerra, AS; Ziegler, MG, 1985)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199024 (61.54)18.7374
1990's9 (23.08)18.2507
2000's5 (12.82)29.6817
2010's0 (0.00)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Chandrasekaran, VP1
Parthasarathy, A1
Muruga, B1
Tesfaye, H1
Průsa, R1
Doupovcová, J1
Chan, TY1
Gomersall, CD1
Cheng, CA1
Woo, J1
Koh, YI1
Choi, IS1
Charytan, D1
Jansen, K1
Buckley, BM2
Braithwaite, RA1
Vale, JA2
Hall, KW1
Dobson, KE1
Dalton, JG1
Ghignone, MC1
Penner, SB1
Boldy, DA1
Benowitz, NL2
Osterloh, J1
Goldschlager, N1
Kaysen, G1
Pond, S1
Forhan, S1
Cuadrado-Gómez, LM1
Manzano-Espinosa, L1
Arrieta, F1
Alvarez-Mon, M1
Flack, JM1
Ryder, KW1
Strickland, D1
Whang, R1
Hagley, MT1
Traeger, SM1
Schuckman, H1
Salem, N1
Rispal, P1
Lasseur, C1
Pellegrin, JL1
Leng, B1
Shannon, M3
Vanpee, D1
Dive, A1
Ossemann, M1
Gillet, JB1
McCleave, DJ1
Phillips, PJ1
Vedig, AE1
Braat, MC1
Jonkers, RE1
Bel, EH1
Van Boxtel, CJ1
Lovejoy, FH3
Lai, CK1
Legge, JS1
Friend, JA1
Anderson, W1
Youl, B1
Mackay, IR1
Epelbaum, S1
Benhamou, PH1
Pautard, JC1
Devoldere, C1
Kremp, O1
Piussan, C1
Assadi, FK1
Deenstra, M1
Haalboom, JR1
Struyvenberg, A1
Elmay, M1
Achour, A1
Ben Dhia, N1
Bergaoui, N1
Mahjoub, S1
Kearney, TE1
Manoguerra, AS1
Curtis, GP1
Ziegler, MG1
Cereda, JM1
Scott, J1
Quigley, EM1
Amitai, Y1
Whyte, KF1
Reid, C1
Addis, GJ1
Whitesmith, R1
Reid, JL1
Siemons, LJ1
Parizel, G1
Niggli, F1
Fanconi, S1
Ghelfi, D1
D'Angio, R1
Sabatelli, F1
Smith, SR1
Kendall, MJ1
Kelly, WJ1
Parkin, WG1
Zantvoort, FA1
Derkx, FH1
Boomsma, F1
Roos, PJ1
Schalekamp, MA1
Olson, KR1
Woo, OF1
Pond, SM1
Sawyer, WT1
Caravati, EM1
Ellison, MJ1
Krueger, KA1
Späth, G1
Martin, W1

Reviews

3 reviews available for theophylline and Hypokalemia

ArticleYear
Severe metabolic complications from theophylline intoxication.
    Nephrology (Carlton, Vic.), 2003, Volume: 8, Issue:5

    Topics: Acidosis, Lactic; Aged, 80 and over; Bicarbonates; Carbon Dioxide; Humans; Hypokalemia; Ketosis; Mal

2003
Advances in the treatment of poisoning I.
    Journal of clinical and hospital pharmacy, 1984, Volume: 9, Issue:3

    Topics: Arrhythmias, Cardiac; Cardiac Glycosides; Digitalis Glycosides; Hemoperfusion; Humans; Hypokalemia;

1984
[The acute respiratory insufficiency].
    Munchener medizinische Wochenschrift (1950), 1972, Nov-17, Volume: 114, Issue:46

    Topics: Acute Disease; Asthma; Blood Gas Analysis; Bronchitis; Butyrates; Chronic Disease; Cortisone; Electr

1972

Trials

2 trials available for theophylline and Hypokalemia

ArticleYear
Decrease of plasma potassium due to inhalation of beta-2-agonists: absence of an additional effect of intravenous theophylline.
    European journal of clinical investigation, 1988, Volume: 18, Issue:2

    Topics: Adrenergic beta-Agonists; Adult; Aerosols; Albuterol; Blood Pressure; Drug Interactions; Fenoterol;

1988
Salbutamol induced hypokalaemia: the effect of theophylline alone and in combination with adrenaline.
    British journal of clinical pharmacology, 1988, Volume: 25, Issue:5

    Topics: Adult; Albuterol; Blood Pressure; Drug Interactions; Epinephrine; Female; Heart Rate; Hemodynamics;

1988

Other Studies

34 other studies available for theophylline and Hypokalemia

ArticleYear
Theophylline toxicity: Successful management of a patient with distributive shock secondary to drug overdose.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Acidosis; Albuterol; Bronchodilator Agents; Calcium Gluconate; Charcoal; Drug Combinations; Drug Ove

2020
[Hypokalaemia in a suicide attempt of an adolescent girl].
    Casopis lekaru ceskych, 2008, Volume: 147, Issue:6

    Topics: Adolescent; Female; Humans; Hypokalemia; Suicide, Attempted; Theophylline

2008
Overdose of methyldopa, indapamide and theophylline resulting in prolonged hypotension, marked diuresis and hypokalaemia in an elderly patient.
    Pharmacoepidemiology and drug safety, 2009, Volume: 18, Issue:10

    Topics: Acetaminophen; Aged, 80 and over; Analgesics, Non-Narcotic; Antihypertensive Agents; Combined Modali

2009
Lactic acidosis associated with the usual theophylline dose in a patient with asthma.
    The Korean journal of internal medicine, 2002, Volume: 17, Issue:2

    Topics: Acidosis, Lactic; Adult; Asthma; Bronchodilator Agents; Female; Humans; Hyperglycemia; Hypokalemia;

2002
Theophylline poisoning.
    Lancet (London, England), 1983, Sep-10, Volume: 2, Issue:8350

    Topics: Delayed-Action Preparations; Humans; Hypokalemia; Suicide, Attempted; Theophylline

1983
Metabolic abnormalities associated with intentional theophylline overdose.
    Annals of internal medicine, 1984, Volume: 101, Issue:4

    Topics: Acid-Base Imbalance; Adolescent; Adult; Female; Humans; Hyperglycemia; Hypokalemia; Insulin; Leukocy

1984
Massive catecholamine release from caffeine poisoning.
    JAMA, 1982, Sep-03, Volume: 248, Issue:9

    Topics: Adult; Affective Symptoms; Caffeine; Catecholamines; Female; Humans; Hyperglycemia; Hyperventilation

1982
[Severe hypokalemia in an attempted suicide by theophyllines].
    Anales de medicina interna (Madrid, Spain : 1984), 1994, Volume: 11, Issue:10

    Topics: Adolescent; Female; Humans; Hypokalemia; Suicide, Attempted; Theophylline

1994
Metabolic correlates of theophylline therapy: a concentration-related phenomenon.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:2

    Topics: Case-Control Studies; Humans; Hyperglycemia; Hypokalemia; Hyponatremia; Hypophosphatemia; Magnesium;

1994
Pronounced metabolic response to modest theophylline overdose.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:2

    Topics: Acidosis, Lactic; Adolescent; Drug Overdose; Humans; Hyperglycemia; Hypokalemia; Hypophosphatemia; L

1994
[Severe hyponatremia and hypokalemia induced by a moderate overdose of theophylline].
    Presse medicale (Paris, France : 1983), 1994, Jan-29, Volume: 23, Issue:3

    Topics: Aged; Bronchopneumonia; Chronic Disease; Humans; Hypokalemia; Hyponatremia; Male; Theophylline

1994
Hypokalemia, hyperglycemia and plasma catecholamine activity after severe theophylline intoxication.
    Journal of toxicology. Clinical toxicology, 1994, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Catecholamines; Child; Humans; Hyperglycemia; Hypokalemia; Middle Aged; Poi

1994
Refractory seizure with hypokalaemia.
    Postgraduate medical journal, 2001, Volume: 77, Issue:905

    Topics: Aged; Bronchodilator Agents; Diagnosis, Differential; Drug Overdose; Female; Humans; Hypokalemia; Me

2001
Compartmental shift of potassium--a result of sympathomimetic overdose.
    Australian and New Zealand journal of medicine, 1978, Volume: 8, Issue:2

    Topics: Adolescent; Ephedrine; Humans; Hypokalemia; Male; Poisoning; Potassium; Theophylline

1978
Quantification of theophylline-induced eosinopenia and hypokalaemia in healthy volunteers.
    Clinical pharmacokinetics, 1992, Volume: 22, Issue:3

    Topics: Adult; Eosinophils; Female; Humans; Hypokalemia; Leukopenia; Male; Theophylline

1992
Effect of acute versus chronic intoxication on clinical features of theophylline poisoning in children.
    The Journal of pediatrics, 1992, Volume: 121, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Arrhythmias, Cardiac; Bicarbonates; Child; Child, Pre

1992
Air-driven nebulised high-dose salbutamol in severe chronic obstructive airways disease: is it safe?
    Respiration; international review of thoracic diseases, 1991, Volume: 58, Issue:5-6

    Topics: Aged; Albuterol; Delayed-Action Preparations; Drug Therapy, Combination; Female; Heart Rate; Humans;

1991
Acute theophylline intoxication.
    Annals of emergency medicine, 1991, Volume: 20, Issue:10

    Topics: Acidosis; Adult; Antacids; Drug Overdose; Emergencies; Fluid Therapy; Humans; Hypokalemia; Male; Pot

1991
[Respiratory arrest in an asthmatic girl treated with beta-2-mimetics and theophylline. Possible role of hypokalemia in sudden death in asthmatic patients].
    Annales de pediatrie, 1989, Volume: 36, Issue:7

    Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Child; Death, Sudden; Drug Interactions; Female; Humans

1989
Hypokalemia after theophylline intoxication. The effects of acute vs chronic poisoning.
    Archives of internal medicine, 1989, Volume: 149, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Child; Child, Preschool; C

1989
Therapy of acute bronchospasm. Complicated by lactic acidosis and hypokalemia.
    Clinical pediatrics, 1989, Volume: 28, Issue:6

    Topics: Acidosis, Lactic; Acute Disease; Albuterol; Bronchial Spasm; Child, Preschool; Drug Therapy, Combina

1989
[Hypokalemia in a patient treated with theophylline. A case].
    Presse medicale (Paris, France : 1983), 1988, Sep-24, Volume: 17, Issue:32

    Topics: Aged; Drug Therapy, Combination; Humans; Hypokalemia; Male; Theophylline

1988
Theophylline toxicity and the beta-adrenergic system.
    Annals of internal medicine, 1985, Volume: 102, Issue:6

    Topics: Acidosis; Adolescent; Aminophylline; Animals; Catecholamines; Disease Models, Animal; Dogs; Female;

1985
Endoscopic removal of pharmacobezoar of slow release theophylline.
    British medical journal (Clinical research ed.), 1986, Nov-01, Volume: 293, Issue:6555

    Topics: Adolescent; Bezoars; Endoscopy; Female; Humans; Hypokalemia; Stomach; Suicide, Attempted; Theophylli

1986
Hypokalemia in acute theophylline poisoning.
    The American journal of emergency medicine, 1988, Volume: 6, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Child; Child, Preschool; Combined Modality Therapy; Hemoperfusion;

1988
Prolonged runs of ventricular tachycardia as a complication of theophylline intoxication. Report of a case.
    Acta cardiologica, 1986, Volume: 41, Issue:6

    Topics: Aged; Electrocardiography; Heart Ventricles; Humans; Hypokalemia; Lung Diseases, Obstructive; Male;

1986
Hypokalemia in theophylline intoxication.
    The Journal of pediatrics, 1987, Volume: 111, Issue:1

    Topics: Adolescent; Delayed-Action Preparations; Female; Humans; Hypokalemia; Potassium; Suicide, Attempted;

1987
Management considerations in treating metabolic abnormalities associated with theophylline overdose.
    Archives of internal medicine, 1987, Volume: 147, Issue:10

    Topics: Adult; Charcoal; Electrocardiography; Humans; Hyperkalemia; Hypokalemia; Male; Potassium; Potassium

1987
Potentiation of the adverse effects of intravenous terbutaline by oral theophylline.
    British journal of clinical pharmacology, 1986, Volume: 21, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Blood Glucose; Blood Pressure; Drug Evaluation; Drug Synerg

1986
Charcoal hemoperfusion treatment of severe theophylline toxicity.
    Australian and New Zealand journal of medicine, 1985, Volume: 15, Issue:1

    Topics: Adult; Charcoal; Hemoperfusion; Humans; Hyperglycemia; Hypokalemia; Male; Theophylline

1985
Theophylline and serum electrolytes.
    Annals of internal medicine, 1986, Volume: 104, Issue:1

    Topics: Humans; Hypokalemia; Potassium; Theophylline

1986
Theophylline overdose: acute single ingestion versus chronic repeated overmedication.
    The American journal of emergency medicine, 1985, Volume: 3, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Chronic Disease; Delay

1985
Hypokalemia, hyperglycemia, and acidosis after intentional theophylline overdose.
    The American journal of emergency medicine, 1985, Volume: 3, Issue:5

    Topics: Acidosis; Adult; Female; Fluid Therapy; Humans; Hyperglycemia; Hypokalemia; Male; Potassium Chloride

1985
[Intoxication with Coritrat (an anti-arrhythmia combination drug)].
    Munchener medizinische Wochenschrift (1950), 1969, Feb-21, Volume: 111, Issue:8

    Topics: Adult; Anti-Arrhythmia Agents; Barbiturates; Electrocardiography; Heart; Humans; Hypokalemia; Kidney

1969