theophylline has been researched along with Heart Defects, Congenital in 11 studies
Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To help understand optimal aminophylline (salt formulation of theophylline) dosing strategies in this population, a population-based pharmacokinetic model was developed using nonlinear mixed-effects modeling (NONMEM) from 71 children (median age 5 months; 90% range 1 week to 10 years) who underwent cardiac surgery requiring CPB and received aminophylline as part of a previous randomized controlled trial." | 2.82 | Theophylline Population Pharmacokinetics and Dosing in Children Following Congenital Heart Surgery With Cardiopulmonary Bypass. ( Axelrod, DM; Frymoyer, A; Grimm, PC; Su, F; Sutherland, SM, 2016) |
| "Theophylline has been shown to be a potent cardiovascular teratogen in animals, but there has been no evidence linking theophylline with congenital anomalies in infants." | 1.28 | Cardiovascular anomalies associated with prenatal exposure to theophylline. ( Myers, TL; Park, JM; Schmer, V, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frymoyer, A | 1 |
| Su, F | 1 |
| Grimm, PC | 1 |
| Sutherland, SM | 1 |
| Axelrod, DM | 1 |
| LANG, EF | 1 |
| Morgan, WJ | 1 |
| Taussig, LM | 1 |
| Gilbert, EF | 2 |
| Bruyere, HJ | 2 |
| Ishikawa, S | 1 |
| Cheung, MO | 1 |
| Hodach, RJ | 1 |
| Park, JM | 1 |
| Schmer, V | 1 |
| Myers, TL | 1 |
| Lin, CI | 1 |
| Tao, PL | 1 |
| Chang, YF | 1 |
| Chiang, BN | 1 |
| Gnezditskaia, EV | 1 |
| Bukhova, VP | 1 |
| Zakharova, NA | 1 |
| Matsuoka, R | 1 |
| Fang, TT | 1 |
| Nishikawa, T | 1 |
| Opitz, JM | 1 |
| Richards, W | 1 |
| Weigand, KH | 1 |
| Menner, K | 2 |
| Rautenburg, HW | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00005279] | 0 participants | Observational | 1971-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for theophylline and Heart Defects, Congenital
| Article | Year |
|---|---|
The chronic bronchitis complex in children.
Topics: Adrenergic beta-Agonists; Adult; Age Factors; Air Pollution; Anti-Bacterial Agents; Asthma; Bronchit | 1984 |
Differential diagnosis of childhood asthma.
Topics: Age Factors; Asthma; Child; Child Health Services; Child, Institutionalized; Cystic Fibrosis; Defici | 1974 |
1 trial available for theophylline and Heart Defects, Congenital
| Article | Year |
|---|---|
Theophylline Population Pharmacokinetics and Dosing in Children Following Congenital Heart Surgery With Cardiopulmonary Bypass.
Topics: Adolescent; Aminophylline; Cardiopulmonary Bypass; Cardiotonic Agents; Child; Child, Preschool; Dose | 2016 |
8 other studies available for theophylline and Heart Defects, Congenital
| Article | Year |
|---|---|
[ON THE DIAGNOSIS OF LEFT-RIGHT SHUNT WITH THE DYE DILUTION TECHNIC].
Topics: Adolescent; Child; Diagnosis; Dye Dilution Technique; Heart Defects, Congenital; Hemodynamics; Human | 1965 |
The effects of methylxanthines on catecholamine-stimulated and normal chick embryos.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Abnormalities, Drug-Induced; Animals; Aortic Aneurysm; Aortic A | 1977 |
Cardiovascular anomalies associated with prenatal exposure to theophylline.
Topics: Adult; Asthma; Drug Administration Schedule; Female; Heart Defects, Congenital; Humans; Infant, Newb | 1990 |
Pacemaker activity is modulated by tissue levels of cyclic adenosine 3',5'-monophosphate in human atrial fibers.
Topics: Action Potentials; Adult; Atrial Function; Child, Preschool; Cyclic AMP; Cyclic GMP; Epinephrine; Fe | 1989 |
[Receptors for the secretory component on human thymic lymphocytes. Stimulation of their expression as affected by adenosine, theophylline and a thymic lymphocyte supernatant].
Topics: Adenosine; Adolescent; Cell Extracts; Child; Child, Preschool; Colostrum; Female; Fluorescent Antibo | 1987 |
Experimentally induced cardiovascular malformations in the chick embryo. Part II. Teratogenic effect of Tedral (theophylline, ephedrine, and phenobarbital) on cardiac development in chick embryos.
Topics: Animals; Cardiovascular System; Chick Embryo; Dose-Response Relationship, Drug; Drug Combinations; D | 1987 |
[Pharmacodynamics of cardiac output in childhood].
Topics: Adolescent; Amyl Nitrite; Aortic Valve Stenosis; Bronchodilator Agents; Cardiac Output; Child; Child | 1971 |
[Studies on the hemodynamic effect of Complamine].
Topics: Adolescent; Blood Circulation; Blood Pressure; Cardiac Catheterization; Child; Child, Preschool; Fem | 1967 |