Compounds > theophylline
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theophylline and Esophageal Reflux

theophylline has been researched along with Esophageal Reflux in 32 studies

Research Excerpts

ExcerptRelevanceReference
"There is evidence that theophylline therapy inhibits lower esophageal sphincter pressure and enhances gastroesophageal reflux in normal adults and adult asthmatics."9.05Quantitative gastroesophageal reflux and pulmonary function in asthmatic children and normal adults receiving placebo, theophylline, and metaproterenol sulfate therapy. ( Berquist, WE; Katz, R; Rachelefsky, GS; Rowshan, N; Siegel, S; Welch, M, 1984)
" Apneas of greater than 10 seconds were recorded, as well as the occurrence of bradycardia or desaturation."7.71Apnea at discharge and gastro-esophageal reflux in the preterm infant. ( Barrington, KJ; Rich, W; Tan, K, 2002)
"The aim of the study was to determine whether gastro-oesophageal (GO)-reflux was increased by normal maintenance doses of theophylline, and if so, whether this was detrimental to lung function in asthmatic patients with symptoms of reflux."7.67Influence of theophylline on gastro-oesophageal reflux and asthma. ( Ekström, T; Tibbling, L, 1988)
" If no cause is found, the diagnosis of idiopathic infantile apnea is made."7.67Infantile apnea. ( McCulloch, K; Vidyasagar, D, 1986)
" On the other day, the patients received sustained-release theophylline, 200 mg twice a day, or in a dosage taken previously to achieve a serum theophylline level of 55 to 110 mumol/L."5.28The effects of inhaled albuterol and oral theophylline on gastroesophageal reflux in patients with gastroesophageal reflux disease and obstructive lung disease. ( Austin, J; Rohwedder, JJ; Ruzkowski, CJ; Sanowski, RA; Waring, JP, 1992)
" Obese and non-obese subjects with asthma had similar airflow limitation and bronchodilator responsiveness, but obese participants had increased sleep disturbance and gastroesophageal reflux disease, higher cytokine levels, and a trend towards increased exacerbations when treated with theophylline."5.12Effect of obesity on clinical presentation and response to treatment in asthma. ( Allayee, H; Cohen, RI; Dixon, AE; Holbrook, JT; Irvin, CG; Lima, JJ; Shade, DM; Skloot, GS; Smith, LJ; Wise, RA, 2006)
"There is evidence that theophylline therapy inhibits lower esophageal sphincter pressure and enhances gastroesophageal reflux in normal adults and adult asthmatics."5.05Quantitative gastroesophageal reflux and pulmonary function in asthmatic children and normal adults receiving placebo, theophylline, and metaproterenol sulfate therapy. ( Berquist, WE; Katz, R; Rachelefsky, GS; Rowshan, N; Siegel, S; Welch, M, 1984)
" Apneas of greater than 10 seconds were recorded, as well as the occurrence of bradycardia or desaturation."3.71Apnea at discharge and gastro-esophageal reflux in the preterm infant. ( Barrington, KJ; Rich, W; Tan, K, 2002)
"The treatment of neonatal apnea and bradycardia with methylated xanthines--theophylline and caffeine--is generally accepted."3.68[Effect of methylxanthines on periodic respiration and acid gastroesophageal reflux in newborn infants]. ( Heimann, G; Koch, G; Skopnik, H, 1990)
"The aim of the study was to determine whether gastro-oesophageal (GO)-reflux was increased by normal maintenance doses of theophylline, and if so, whether this was detrimental to lung function in asthmatic patients with symptoms of reflux."3.67Influence of theophylline on gastro-oesophageal reflux and asthma. ( Ekström, T; Tibbling, L, 1988)
" If no cause is found, the diagnosis of idiopathic infantile apnea is made."3.67Infantile apnea. ( McCulloch, K; Vidyasagar, D, 1986)
"Gastroesophageal reflux disease (GERD) is increasing due to adoption of a western life style and an aging society in recent years."2.42[GERD: guidance in changing life-style]. ( Harasawa, S; Nagoshi, A, 2004)
"Prevalence of gastroesophageal reflux had been detected in 24% of asthmatic patients, in some cases as a cause of asthma exacerbation."2.42[Treatment of bronchial asthma exacerbation]. ( Płusa, T, 2004)
"Gastroesophageal reflux (GER) and its many manifestations are extremely common problems."2.37Respiratory complications of gastroesophageal reflux. ( Barish, CF; Castell, DO; Wu, WC, 1985)
"Concomitant GERD was revealed in 45."1.33[Gastroesophageal reflux disease and respiratory apparatus pathology: the evidence of interrelation and unsolved problems]. ( Chereĭskaia, NK; Isakov, VA; Ivanova, OV; Paleev, NR, 2005)
"GERD was present in 86."1.32[Prevalence of gastroesophageal reflux disease in patients with bronchial asthma]. ( Bocheńska-Marciniak, M; Górski, P, 2004)
"In order to study risk factors for gastroesophageal reflux (RGO), we have analysed the clinical particulars, the spirometry and the different therapies of chronic asthmatics with and without RGO."1.29[Risk factors for gastroesophageal reflux in chronic asthma]. ( Charlery, S; Denjean, A; Duroux, P; Escourrou, P; Gandolfo, JY; Gaultier, C; Hervé, P; Petitpretz, P; Salmeron, S; Simonneau, G, 1993)
" On the other day, the patients received sustained-release theophylline, 200 mg twice a day, or in a dosage taken previously to achieve a serum theophylline level of 55 to 110 mumol/L."1.28The effects of inhaled albuterol and oral theophylline on gastroesophageal reflux in patients with gastroesophageal reflux disease and obstructive lung disease. ( Austin, J; Rohwedder, JJ; Ruzkowski, CJ; Sanowski, RA; Waring, JP, 1992)
"Gastroesophageal reflux (GER) may contribute to the persistence of asthma and may be triggered and/or exacerbated by treatment with bronchodilatory and cortisone drugs."1.28[Gastro-esophageal reflux and asthma. Clinical experience]. ( Barberio, G; Di Pasquale, F; Morabito, L; Pajno, GB; Pollicino, A; Ruggeri, C; Terranova, ML, 1989)
"Gastroesophageal reflux, diagnosed by positive acid reflux test, occurred in nine patients."1.26Gastroesophageal reflux in steroid-dependent asthmatic youths. ( Christie, DL; Shapiro, GG, 1979)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199017 (53.13)18.7374
1990's7 (21.88)18.2507
2000's8 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arand, M1
Balfour-Lynn, IM1
Elborn, JS1
Nagoshi, A1
Harasawa, S1
Bocheńska-Marciniak, M1
Górski, P1
Płusa, T1
Paleev, NR1
Isakov, VA1
Chereĭskaia, NK1
Ivanova, OV1
Dixon, AE1
Shade, DM1
Cohen, RI1
Skloot, GS1
Holbrook, JT1
Smith, LJ1
Lima, JJ1
Allayee, H1
Irvin, CG1
Wise, RA1
Dolovich, J1
Hargreave, FE1
Zeiger, RS1
Branscomb, BV1
Berquist, WE2
Rachelefsky, GS2
Rowshan, N1
Siegel, S1
Katz, R1
Welch, M1
Shapiro, GG2
Kadden, M1
Siegel, SC1
Katz, RM1
Mickey, MR1
Ament, ME1
Hervé, P1
Escourrou, P1
Salmeron, S1
Gandolfo, JY1
Charlery, S1
Denjean, A1
Petitpretz, P1
Simonneau, G1
Gaultier, C1
Duroux, P1
Jaspersen, D1
Barrington, KJ1
Tan, K1
Rich, W1
Christie, DL1
Martin, RJ1
Ruzkowski, CJ1
Sanowski, RA1
Austin, J1
Rohwedder, JJ1
Waring, JP1
Ojeda Casas, JA1
García Ara, MC1
Martín Muñoz, F1
Díaz Pena, JM1
Añibarro Bausera, B1
Escobar Castro, H1
Stein, MR1
Skopnik, H1
Koch, G1
Heimann, G1
Barberio, G1
Ruggeri, C1
Pajno, GB1
Morabito, L1
Pollicino, A1
Di Pasquale, F1
Terranova, ML1
Mansfield, LE1
Barish, CF1
Wu, WC1
Castell, DO1
Li, JT1
Reed, CE1
Conti Nibali, S1
Famulari, C1
Pustorino, S1
Magazzù, G1
Hubert, D1
Gaudric, M1
Guerre, J1
Lockhart, A1
Marsac, J1
Ekström, TK1
Tibbling, LI1
Ekström, T1
Tibbling, L1
Vandenplas, Y1
De Wolf, D1
Sacre, L1
McCulloch, K1
Vidyasagar, D1

Reviews

10 reviews available for theophylline and Esophageal Reflux

ArticleYear
"CF asthma": what is it and what do we do about it?
    Thorax, 2002, Volume: 57, Issue:8

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Bronchial Hyperreactivity; Bronchodila

2002
[GERD: guidance in changing life-style].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Constipation; Diet; Gastroesophag

2004
[Treatment of bronchial asthma exacerbation].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004, Volume: 16 Suppl 1

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Bronchodilator Age

2004
Strategies in the control of asthma.
    The Medical clinics of North America, 1981, Volume: 65, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Allergens; Asthma; A

1981
Special considerations in the approach to asthma in infancy and early childhood.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1983, Volume: 20, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Aerosols; Air Pollutants; Allergens; Asthma; Bron

1983
The difficult asthmatic.
    Clinics in chest medicine, 1984, Volume: 5, Issue:4

    Topics: Asthma; Diabetes Complications; Diagnosis, Differential; Dyspnea, Paroxysmal; Female; Gastroesophage

1984
[Reflux associated respiratory tract diseases].
    Deutsche medizinische Wochenschrift (1946), 1996, Apr-05, Volume: 121, Issue:14

    Topics: Bronchiectasis; Bronchitis; Bronchodilator Agents; Chronic Disease; Esophagogastric Junction; Gastro

1996
Nocturnal asthma.
    Clinics in chest medicine, 1992, Volume: 13, Issue:3

    Topics: Adrenal Cortex Hormones; Asthma; Bronchial Hyperreactivity; Circadian Rhythm; Gastroesophageal Reflu

1992
[Asthma and gastroesophageal reflux. Outcome of asthma after longterm medical treatment of the reflux].
    Anales espanoles de pediatria, 1990, Volume: 33, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Child; Child, Preschool; Cimetidine; E

1990
Respiratory complications of gastroesophageal reflux.
    Archives of internal medicine, 1985, Volume: 145, Issue:10

    Topics: Adrenergic beta-Agonists; Adult; Asthma; Child; Child, Preschool; Esophagogastric Junction; Gastroes

1985

Trials

5 trials available for theophylline and Esophageal Reflux

ArticleYear
Effect of obesity on clinical presentation and response to treatment in asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2006, Volume: 43, Issue:7

    Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Cytokines; Dis

2006
Quantitative gastroesophageal reflux and pulmonary function in asthmatic children and normal adults receiving placebo, theophylline, and metaproterenol sulfate therapy.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:2

    Topics: Adolescent; Adult; Asthma; Child; Female; Gastroesophageal Reflux; Humans; Male; Metaproterenol; Pla

1984
Effect of theophylline on gastroesophageal reflux in normal adults.
    The Journal of allergy and clinical immunology, 1981, Volume: 67, Issue:5

    Topics: Adult; Esophagogastric Junction; Female; Gastroesophageal Reflux; Heartburn; Humans; Male; Placebos;

1981
Effect of theophylline on gastroesophageal reflux in patients with asthma.
    The Journal of allergy and clinical immunology, 1988, Volume: 81, Issue:6

    Topics: Adrenergic beta-Agonists; Adult; Aged; Asthma; Double-Blind Method; Female; Gastroesophageal Reflux;

1988
Can mild bronchospasm reduce gastroesophageal reflux?
    The American review of respiratory disease, 1989, Volume: 139, Issue:1

    Topics: Aged; Asthma; Bronchial Provocation Tests; Esophagogastric Junction; Female; Forced Expiratory Volum

1989

Other Studies

17 other studies available for theophylline and Esophageal Reflux

ArticleYear
[Nocturnal shortness of breath: in asthma look for reflux -- is it worthwhile?].
    MMW Fortschritte der Medizin, 2008, Dec-11, Volume: 150, Issue:51-52

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Asthma; Bronchodilator Agents; Gastroesophageal Reflux; Hum

2008
[Prevalence of gastroesophageal reflux disease in patients with bronchial asthma].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004, Volume: 16, Issue:96

    Topics: Adult; Asthma; Body Mass Index; Bronchodilator Agents; Female; Gastroesophageal Reflux; Glucocortico

2004
[Gastroesophageal reflux disease and respiratory apparatus pathology: the evidence of interrelation and unsolved problems].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2005, Issue:6

    Topics: Adult; Aged; Asthma; Bronchi; Bronchodilator Agents; Female; Gastroesophageal Reflux; Humans; Male;

2005
Gastroesophageal reflux and asthma.
    The Journal of pediatrics, 1984, Volume: 104, Issue:6

    Topics: Asthma; Child; Gastroesophageal Reflux; Humans; Theophylline

1984
[Risk factors for gastroesophageal reflux in chronic asthma].
    Revue des maladies respiratoires, 1993, Volume: 10, Issue:6

    Topics: Adolescent; Adult; Aged; Asthma; Chronic Disease; Female; Gastric Acidity Determination; Gastroesoph

1993
Apnea at discharge and gastro-esophageal reflux in the preterm infant.
    Journal of perinatology : official journal of the California Perinatal Association, 2002, Volume: 22, Issue:1

    Topics: Apnea; Bronchodilator Agents; Gastroesophageal Reflux; Humans; Infant, Newborn; Infant, Premature; I

2002
Gastroesophageal reflux in steroid-dependent asthmatic youths.
    Pediatrics, 1979, Volume: 63, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Antacids; Asthma; Beclomethasone; Child; Gastroesophageal Reflu

1979
The effects of inhaled albuterol and oral theophylline on gastroesophageal reflux in patients with gastroesophageal reflux disease and obstructive lung disease.
    Archives of internal medicine, 1992, Volume: 152, Issue:4

    Topics: Administration, Inhalation; Administration, Oral; Adult; Aged; Albuterol; Delayed-Action Preparation

1992
Effect of theophylline on gastroesophageal reflux.
    The Journal of allergy and clinical immunology, 1990, Volume: 85, Issue:1 Pt 1

    Topics: Asthma; Gastroesophageal Reflux; Humans; Theophylline

1990
[Effect of methylxanthines on periodic respiration and acid gastroesophageal reflux in newborn infants].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1990, Volume: 138, Issue:3

    Topics: Bradycardia; Caffeine; Citrates; Drug Combinations; Drug Therapy, Combination; Gastric Acidity Deter

1990
[Gastro-esophageal reflux and asthma. Clinical experience].
    Minerva pediatrica, 1989, Volume: 41, Issue:7

    Topics: Asthma; Child; Clinical Protocols; Female; Gastroesophageal Reflux; Humans; Male; Theophylline

1989
Effects of theophylline in gastroesophageal reflux.
    The Journal of allergy and clinical immunology, 1989, Volume: 84, Issue:3

    Topics: Asthma; Data Interpretation, Statistical; Gastroesophageal Reflux; Humans; Theophylline

1989
Nocturnal asthma and timing of treatment.
    The American journal of medicine, 1985, Dec-20, Volume: 79, Issue:6A

    Topics: Adrenergic beta-Antagonists; Airway Resistance; Aminophylline; Asthma; Bronchi; Circadian Rhythm; De

1985
Gastroesophageal reflux and asthma medication.
    Acta paediatrica Scandinavica, 1987, Volume: 76, Issue:4

    Topics: Adrenergic beta-Agonists; Adult; Asthma; Female; Gastroesophageal Reflux; Humans; Theophylline

1987
Influence of theophylline on gastro-oesophageal reflux and asthma.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:4

    Topics: Asthma; Female; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Resp

1988
Influence of xanthines on gastroesophageal reflux in infants at risk for sudden infant death syndrome.
    Pediatrics, 1986, Volume: 77, Issue:6

    Topics: Administration, Oral; Caffeine; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concentration; Infant;

1986
Infantile apnea.
    American family physician, 1986, Volume: 34, Issue:3

    Topics: Apnea; Breast Feeding; Diagnosis, Differential; Gastroesophageal Reflux; Humans; Infant; Infant, New

1986