theophylline has been researched along with Epilepsy, Tonic-Clonic in 12 studies
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Theophylline was administered due to postoperative bradycardia." | 3.80 | Seizures after heart transplantation--two cases of non-immunosuppressant drug interactions in young patients. ( Baszyńska-Wachowiak, H; Buczkowski, P; Jemielity, M; Pawłowska, M; Perek, B; Straburzyńska-Migaj, E; Urbanowicz, T, 2014) |
| "We report on two female patients, aged 22 and 50 receiving high-dose theophylline, 750-1,500 mg/day, for bronchial asthma, who were admitted to hospital with severe grand-mal seizures, in one primary focal with secondary generalisation." | 3.67 | [Grand mal series and status using high-dose theophylline medication]. ( Hager, H; Pohlmann-Eden, B, 1989) |
| "Nitric oxide may be involved in seizure phenomena even though data often seem to be contradictory." | 1.29 | NG-nitro-L-arginine, a nitric oxide synthase inhibitor, and seizure susceptibility in four seizure models in mice. ( Borowicz, KK; Błaszczak, P; Czuczwar, SJ; Drelewska, E; Kleinrok, Z; Urbańska, EM, 1996) |
| " We concluded that drug dosage should be reduced and the possibility of seizure activity at lower serum concentration than would be otherwise anticipated should be kept in mind." | 1.27 | Seizures due to theophylline overdose. ( Kolischenko, A; Singer, EP, 1985) |
| "Theophylline was removed from the serum by the uncoated charcoal column, as shown by an extraction efficiency approaching 100%." | 1.26 | Massive theophylline overdose. Rapid elimination by charcoal hemoperfusion. ( Ehlers, SM; Sawchuk, RJ; Zaske, DE, 1978) |
| "After treatment for cor pulmonale theophylline clearance improved; however, with the subsequent onset of fever and pneumonia the clearance decreased again, illustrating the potential lability of theophylline clearance." | 1.26 | Grand mal seizure induced by oral theophylline. ( Matthay, MA; Matthay, RA; Weinberger, MM, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (66.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Urbanowicz, T | 1 |
| Pawłowska, M | 1 |
| Buczkowski, P | 1 |
| Perek, B | 1 |
| Baszyńska-Wachowiak, H | 1 |
| Straburzyńska-Migaj, E | 1 |
| Jemielity, M | 1 |
| Dean, LS | 1 |
| Brown, JW | 1 |
| Moscariello, A | 1 |
| Jacob, F | 1 |
| Harf, C | 1 |
| Welter, R | 1 |
| Urbańska, EM | 1 |
| Drelewska, E | 1 |
| Borowicz, KK | 1 |
| Błaszczak, P | 1 |
| Kleinrok, Z | 1 |
| Czuczwar, SJ | 1 |
| Okada, S | 1 |
| Teramoto, S | 1 |
| Matsuoka, R | 1 |
| Ehlers, SM | 1 |
| Zaske, DE | 1 |
| Sawchuk, RJ | 1 |
| Fleetham, JA | 1 |
| Ginsburg, JC | 1 |
| Nakatsu, K | 1 |
| Wigle, RD | 1 |
| Munt, PW | 1 |
| Matthay, RA | 1 |
| Matthay, MA | 1 |
| Weinberger, MM | 1 |
| Hager, H | 1 |
| Pohlmann-Eden, B | 1 |
| Modi, KB | 1 |
| Horn, EH | 1 |
| Bryson, SM | 1 |
| Mitchell, EA | 1 |
| Dower, JC | 1 |
| Green, RJ | 1 |
| Singer, EP | 1 |
| Kolischenko, A | 1 |
12 other studies available for theophylline and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Seizures after heart transplantation--two cases of non-immunosuppressant drug interactions in young patients.
Topics: Adult; Antiemetics; Bradycardia; Brain; Dopamine D2 Receptor Antagonists; Drug Interactions; Epileps | 2014 |
Massive theophylline overdose. Survival without hemoperfusion.
Topics: Bronchodilator Agents; Choline; Diazepam; Epilepsy, Tonic-Clonic; Female; Hemoperfusion; Humans; Mid | 1982 |
[Theophylline and seizures].
Topics: Aged; Aged, 80 and over; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle | 1993 |
NG-nitro-L-arginine, a nitric oxide synthase inhibitor, and seizure susceptibility in four seizure models in mice.
Topics: Aminooxyacetic Acid; Aminophylline; Animals; Convulsants; Drug Synergism; Electroshock; Enzyme Inhib | 1996 |
Recovery from theophylline toxicity by continuous hemodialysis with filtration.
Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Bronchodilator Agents; Drug Overdose; Epilepsy, Tonic- | 2000 |
Massive theophylline overdose. Rapid elimination by charcoal hemoperfusion.
Topics: Charcoal; Epilepsy, Tonic-Clonic; Female; Hemoperfusion; Humans; Hypotension; Middle Aged; Theophyll | 1978 |
Resin hemoperfusion as treatment for theophylline-induced seizures.
Topics: Aminophylline; Epilepsy, Tonic-Clonic; Hemoperfusion; Humans; Infusions, Parenteral; Male; Middle Ag | 1979 |
Grand mal seizure induced by oral theophylline.
Topics: Administration, Oral; Aged; Epilepsy, Tonic-Clonic; Humans; Male; Metabolic Clearance Rate; Pulmonar | 1976 |
[Grand mal series and status using high-dose theophylline medication].
Topics: Adult; Asthma; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Female; Humans; Middle Aged | 1989 |
Theophylline poisoning and rhabdomyolysis.
Topics: Aged; Epilepsy, Tonic-Clonic; Hemoperfusion; Humans; Male; Rhabdomyolysis; Theophylline | 1985 |
Interaction between carbamazepine and theophylline.
Topics: Asthma; Carbamazepine; Child; Drug Interactions; Epilepsy, Tonic-Clonic; Female; Half-Life; Humans; | 1986 |
Seizures due to theophylline overdose.
Topics: Aged; Bronchial Spasm; Bronchitis; Cerebrovascular Disorders; Epilepsy, Tonic-Clonic; Female; Humans | 1985 |