theophylline has been researched along with Drug Withdrawal Symptoms in 38 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Theophylline is the most widely used anti-asthma drug worldwide and is classified as a bronchodilator, although there is increasing evidence that it may have immunomodulatory effects." | 9.08 | Immunomodulation by theophylline in asthma. Demonstration by withdrawal of therapy. ( Barnes, PJ; Chung, KF; Dominguez, M; Kidney, J; Rose, M; Taylor, PM, 1995) |
| "We investigated whether the deterioration in asthma control reported following cessation of theophylline was due to tolerance to theophylline." | 9.08 | The airway effects of stopping regular oral theophylline in patients with asthma. ( Bennett, JA; Pavord, ID; Tattersfield, AE; Thompson Coon, J; Wilding, PJ, 1998) |
| "Theophylline has been used as a bronchodilator in acute and chronic asthma management, although there is accumulating evidence that it may have anti-inflammatory effects." | 9.08 | Effect of theophylline withdrawal on airway inflammation in asthma. ( Adachi, M; Akabane, T; Hashimoto, T; Kihara, N; Kobayashi, H; Kohno, Y; Minoguchi, K; Mita, S; Miyamoto, M; Oda, N; Wada, K; Yokoe, T, 1998) |
| "We examined effects of theophylline withdrawal in 17 adult asthmatics whose symptoms were well controlled under a treatment of a combination of theophylline and inhaled beclomethasone dipropionate (iBDP)." | 7.71 | Effects of theophylline withdrawal in well-controlled asthmatics treated with inhaled corticosteroid. ( Baba, K; Hattori, T; Kobayashi, T; Koishikawa, I; Niwa, S; Sakakibara, A; Takagi, K; Yagi, T; Yoshida, K, 2001) |
| "Biochemical changes such as intracellular cAMP and Ca(2+) underlying morphine dependence and tolerance have been suggested." | 7.70 | Attenuation of the development of morphine dependence/tolerance by nefiracetam: involvement of adenosine 3':5'-cyclic monophosphate system. ( Hasegawa, T; Itoh, A; Mamiya, T; Nabeshima, T; Nakayama, S; Noda, Y; Shiotani, T, 2000) |
| "This study was undertaken to investigate the effect of theophylline on serum uric acid levels in children with asthma." | 7.69 | Effect of theophylline on serum uric acid levels in children with asthma. ( Kuroume, T; Maeda, S; Mochizuki, H; Morikawa, A; Shimizu, T; Tokuyama, K, 1994) |
| "An improved protocol was developed for the use of troleandomycin (TAO) in severe, steroid-requiring subjects with asthma." | 7.67 | An improved protocol for the use of troleandomycin (TAO) in the treatment of steroid-requiring asthma. ( Farr, RS; Friedman, BF; Wald, JA, 1986) |
| "Theophylline is the most widely used anti-asthma drug worldwide and is classified as a bronchodilator, although there is increasing evidence that it may have immunomodulatory effects." | 5.08 | Immunomodulation by theophylline in asthma. Demonstration by withdrawal of therapy. ( Barnes, PJ; Chung, KF; Dominguez, M; Kidney, J; Rose, M; Taylor, PM, 1995) |
| "We investigated whether the deterioration in asthma control reported following cessation of theophylline was due to tolerance to theophylline." | 5.08 | The airway effects of stopping regular oral theophylline in patients with asthma. ( Bennett, JA; Pavord, ID; Tattersfield, AE; Thompson Coon, J; Wilding, PJ, 1998) |
| "Theophylline has been used as a bronchodilator in acute and chronic asthma management, although there is accumulating evidence that it may have anti-inflammatory effects." | 5.08 | Effect of theophylline withdrawal on airway inflammation in asthma. ( Adachi, M; Akabane, T; Hashimoto, T; Kihara, N; Kobayashi, H; Kohno, Y; Minoguchi, K; Mita, S; Miyamoto, M; Oda, N; Wada, K; Yokoe, T, 1998) |
| " Dipyridamole, a blocker of adenosine reuptake, induced a significant reduction of morphine dependence." | 3.75 | Functional interaction between purinergic system and opioid withdrawal: in vitro evidence. ( Capasso, A; Gallo, C, 2009) |
| "We examined effects of theophylline withdrawal in 17 adult asthmatics whose symptoms were well controlled under a treatment of a combination of theophylline and inhaled beclomethasone dipropionate (iBDP)." | 3.71 | Effects of theophylline withdrawal in well-controlled asthmatics treated with inhaled corticosteroid. ( Baba, K; Hattori, T; Kobayashi, T; Koishikawa, I; Niwa, S; Sakakibara, A; Takagi, K; Yagi, T; Yoshida, K, 2001) |
| "Biochemical changes such as intracellular cAMP and Ca(2+) underlying morphine dependence and tolerance have been suggested." | 3.70 | Attenuation of the development of morphine dependence/tolerance by nefiracetam: involvement of adenosine 3':5'-cyclic monophosphate system. ( Hasegawa, T; Itoh, A; Mamiya, T; Nabeshima, T; Nakayama, S; Noda, Y; Shiotani, T, 2000) |
| "This study was undertaken to investigate the effect of theophylline on serum uric acid levels in children with asthma." | 3.69 | Effect of theophylline on serum uric acid levels in children with asthma. ( Kuroume, T; Maeda, S; Mochizuki, H; Morikawa, A; Shimizu, T; Tokuyama, K, 1994) |
| "An improved protocol was developed for the use of troleandomycin (TAO) in severe, steroid-requiring subjects with asthma." | 3.67 | An improved protocol for the use of troleandomycin (TAO) in the treatment of steroid-requiring asthma. ( Farr, RS; Friedman, BF; Wald, JA, 1986) |
| "Theophylline therapy was continued in 20 patients and replaced by placebo from day 3 on in the remainder; measurements were repeated on days 5 and 6." | 2.67 | Effects of theophylline withdrawal in severe chronic obstructive pulmonary disease. ( Jörres, RA; Kirsten, DK; Magnussen, H; Wegner, RE, 1993) |
| "Seizures are commonly encountered in patients who do not have epilepsy." | 2.40 | Medical causes of seizures. ( Delanty, N; French, JA; Vaughan, CJ, 1998) |
| "Drug-induced seizures are a potentially serious adverse effect." | 2.39 | Drug-induced seizures in the elderly. Causative agents and optimal management. ( Chatel, DM; Dahdal, WY; Franson, KL; Grossberg, GT; Hay, DP; Kotegal, S; Mirza, WU; Neppe, V; Szwabo, PA, 1995) |
| " However, the dose-response curve against dermorphine inhibition of the response to CCK-8 was bell-shaped and the highest SR concentration also significantly decreased the mu-withdrawal response." | 1.33 | Involvement of the cannabinoid CB1 receptor in the opioid inhibition of the response to cholecystokinin and acute withdrawal response. ( Amico, MC; Morrone, LA; Palmery, M; Romanelli, L; Tucci, P; Valeri, P, 2005) |
| "Adenosine A1 receptors were not desensitized, because the potency of the metabolically stable adenosine analog N6-cyclopentyl-adenosine was unchanged after chronic cocaine withdrawal." | 1.30 | Decreased presynaptic sensitivity to adenosine after cocaine withdrawal. ( Bockaert, J; Manzoni, O; Pujalte, D; Williams, J, 1998) |
| "Theophylline pretreatment prior to acute ethanol administration markedly reduced the duration of ethanol-induced sleep and similarly decreased the intensity and duration of motor incoordination." | 1.27 | Possible role of adenosine in the CNS effects of ethanol. ( Dar, MS; Mustafa, SJ; Wooles, WR, 1983) |
| " The lack of change in the pharmacokinetic profile of theophylline indicates that adjustment of the dosage regimen should not be necessary immediately after smoking withdrawal." | 1.27 | Lack of effect of withdrawal from cigarette smoking on theophylline pharmacokinetics. ( Eldon, MA; Luecker, PW; MacGee, J; Ritschel, WA, 1987) |
| " Plasma concentration monitoring may be necessary for optimal dosing of theophylline in such patients." | 1.27 | Cigarette abstinence, nicotine gum, and theophylline disposition. ( Benowitz, NL; Jacob, P; Lee, BL, 1987) |
| "Pretreatment with clonidine (50 micrograms/kg, IP) significantly decreased the incidence of 11 out of 16 withdrawal signs." | 1.26 | Clonidine suppresses methylxanthine induced quasi-morphine withdrawal syndrome. ( Grant, SJ; Redmond, DE, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (47.37) | 18.7374 |
| 1990's | 12 (31.58) | 18.2507 |
| 2000's | 8 (21.05) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Capasso, A | 2 |
| Gallo, C | 1 |
| Romanelli, L | 2 |
| Morrone, LA | 2 |
| Amico, MC | 2 |
| Palmery, M | 2 |
| Tucci, P | 2 |
| Valeri, P | 2 |
| Gatch, MB | 2 |
| Collier, HO | 6 |
| Tucker, JF | 1 |
| Cuthbert, NJ | 2 |
| Francis, DL | 4 |
| Grant, SJ | 1 |
| Redmond, DE | 1 |
| Dar, MS | 1 |
| Mustafa, SJ | 1 |
| Wooles, WR | 1 |
| Horowitz, DA | 1 |
| Jablonski, WJ | 1 |
| Mehta, KA | 1 |
| Franson, KL | 1 |
| Hay, DP | 1 |
| Neppe, V | 1 |
| Dahdal, WY | 1 |
| Mirza, WU | 1 |
| Grossberg, GT | 1 |
| Chatel, DM | 1 |
| Szwabo, PA | 1 |
| Kotegal, S | 1 |
| Kidney, J | 1 |
| Dominguez, M | 1 |
| Taylor, PM | 1 |
| Rose, M | 1 |
| Chung, KF | 1 |
| Barnes, PJ | 1 |
| Shimizu, T | 1 |
| Morikawa, A | 1 |
| Maeda, S | 1 |
| Mochizuki, H | 1 |
| Tokuyama, K | 1 |
| Kuroume, T | 1 |
| Van Soeren, MH | 1 |
| Sathasivam, P | 1 |
| Spriet, LL | 1 |
| Graham, TE | 1 |
| Kirsten, DK | 1 |
| Wegner, RE | 1 |
| Jörres, RA | 1 |
| Magnussen, H | 1 |
| Bennett, JA | 1 |
| Thompson Coon, J | 1 |
| Pavord, ID | 1 |
| Wilding, PJ | 1 |
| Tattersfield, AE | 1 |
| Delanty, N | 1 |
| Vaughan, CJ | 1 |
| French, JA | 1 |
| Manzoni, O | 1 |
| Pujalte, D | 1 |
| Williams, J | 1 |
| Bockaert, J | 1 |
| Minoguchi, K | 1 |
| Kohno, Y | 1 |
| Oda, N | 1 |
| Wada, K | 1 |
| Miyamoto, M | 1 |
| Yokoe, T | 1 |
| Hashimoto, T | 1 |
| Akabane, T | 1 |
| Kobayashi, H | 1 |
| Mita, S | 1 |
| Kihara, N | 1 |
| Adachi, M | 1 |
| Wallis, CJ | 1 |
| Lal, H | 1 |
| Itoh, A | 1 |
| Shiotani, T | 1 |
| Nakayama, S | 1 |
| Mamiya, T | 1 |
| Hasegawa, T | 1 |
| Noda, Y | 1 |
| Nabeshima, T | 1 |
| Khalili, M | 1 |
| Semnanian, S | 1 |
| Fathollahi, Y | 1 |
| Baba, K | 1 |
| Sakakibara, A | 1 |
| Yagi, T | 1 |
| Niwa, S | 1 |
| Hattori, T | 1 |
| Koishikawa, I | 1 |
| Yoshida, K | 1 |
| Kobayashi, T | 1 |
| Takagi, K | 1 |
| Roy, AC | 1 |
| Butt, NM | 1 |
| Saeed, SA | 1 |
| Ho, LK | 1 |
| Loh, HH | 2 |
| Bhargava, HN | 1 |
| Way, EL | 2 |
| Biaggioni, I | 1 |
| Paul, S | 1 |
| Puckett, A | 1 |
| Arzubiaga, C | 1 |
| Loosmore, S | 1 |
| Armstrong, D | 1 |
| Kleven, MS | 2 |
| Sparber, SB | 2 |
| Wald, JA | 1 |
| Friedman, BF | 1 |
| Farr, RS | 1 |
| Eldon, MA | 1 |
| Luecker, PW | 1 |
| MacGee, J | 1 |
| Ritschel, WA | 1 |
| Lee, BL | 1 |
| Benowitz, NL | 1 |
| Jacob, P | 1 |
| Ho, IK | 1 |
| Hammond, MD | 1 |
| Schneider, C | 2 |
| Greden, JF | 1 |
| Henderson, G | 1 |
3 reviews available for theophylline and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Sites and mechanisms of dependence in the myenteric plexus of guinea pig ileum.
Topics: Acetylcholine; Adenosine; Animals; Clonidine; Cyclic AMP; Guinea Pigs; Humans; Ileum; In Vitro Techn | 1984 |
Drug-induced seizures in the elderly. Causative agents and optimal management.
Topics: Aging; Anti-Bacterial Agents; Anti-Infective Agents; Anticonvulsants; Antidepressive Agents; Antipsy | 1995 |
Medical causes of seizures.
Topics: Acute Kidney Injury; Anticonvulsants; Antitubercular Agents; Blood Pressure; Brain Diseases; Broncho | 1998 |
5 trials available for theophylline and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Immunomodulation by theophylline in asthma. Demonstration by withdrawal of therapy.
Topics: Adjuvants, Immunologic; Adult; Aged; Asthma; Biopsy; Bronchi; Cross-Over Studies; Female; Humans; Im | 1995 |
Caffeine metabolism and epinephrine responses during exercise in users and nonusers.
Topics: Adult; Blood Glucose; Caffeine; Catecholamines; Epinephrine; Exercise; Fatty Acids, Nonesterified; G | 1993 |
Effects of theophylline withdrawal in severe chronic obstructive pulmonary disease.
Topics: Aged; Double-Blind Method; Dyspnea; Exercise Tolerance; Female; Humans; Lung Diseases, Obstructive; | 1993 |
The airway effects of stopping regular oral theophylline in patients with asthma.
Topics: Administration, Oral; Adult; Asthma; Bronchoconstriction; Bronchodilator Agents; Cyclic AMP; Double- | 1998 |
Effect of theophylline withdrawal on airway inflammation in asthma.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Asthma; Bronchial Provocation Tests; Do | 1998 |
30 other studies available for theophylline and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor | 2009 |
Inhibitory control of the acute mu-withdrawal response by indirectly activated adenosine A1 and kappa-opioid systems in the Guinea-pig ileum; reversal by cholecystokinin.
Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Analgesics, Opioid; Animals; Chol | 2005 |
Involvement of the cannabinoid CB1 receptor in the opioid inhibition of the response to cholecystokinin and acute withdrawal response.
Topics: Acute Disease; Adenosine A1 Receptor Antagonists; Analgesics, Opioid; Animals; Benzoxazines; Cholecy | 2005 |
Tolerance to the antinociceptive effects of ethanol during ethanol withdrawal.
Topics: Analgesics; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Central Nervous System Depr | 2006 |
Character and meaning of quasi-morphine withdrawal phenomena elicited by methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Huma | 1981 |
Clonidine suppresses methylxanthine induced quasi-morphine withdrawal syndrome.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Behavior, Animal; Clonidine; Humans; Male; Morphine Dependence | 1982 |
Possible role of adenosine in the CNS effects of ethanol.
Topics: Adenosine; Alcoholic Intoxication; Alcoholism; Animals; Body Temperature; Central Nervous System; Di | 1983 |
Apnea associated with theophylline withdrawal in a term neonate.
Topics: Apnea; Caffeine; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange | 1982 |
Effect of theophylline on serum uric acid levels in children with asthma.
Topics: Adolescent; Asthma; Child; Female; Humans; Male; Substance Withdrawal Syndrome; Theophylline; Uric A | 1994 |
Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Affinity Labels; Animals; Cocaine; Dipyri | 1998 |
The effects of adenosine ligands R-PIA and CPT on ethanol withdrawal.
Topics: Adenosine; Alcohol Drinking; Animals; Anti-Anxiety Agents; Central Nervous System Depressants; Ethan | 1999 |
Adenosine receptors are involved in the control of acute naloxone-precipitated withdrawal: in vitro evidence.
Topics: Adenosine; Animals; Caffeine; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Naloxone; | 2000 |
Attenuation of the development of morphine dependence/tolerance by nefiracetam: involvement of adenosine 3':5'-cyclic monophosphate system.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Cyclic AMP; Drug Tolerance; Male; Mice; Morphine; Morphin | 2000 |
Caffeine increases paragigantocellularis neuronal firing rate and induces withdrawal signs in morphine-dependent rats.
Topics: Adenosine; Analgesics, Opioid; Animals; Caffeine; Electrophysiology; Male; Medulla Oblongata; Microi | 2001 |
Effects of theophylline withdrawal in well-controlled asthmatics treated with inhaled corticosteroid.
Topics: Adult; Aged; Anti-Asthmatic Agents; Asthma; Beclomethasone; Blood Proteins; Bronchodilator Agents; D | 2001 |
Morphone abstinence and quasi-abstinence effects after phosphodiesterase inhibitors and naloxone.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffei | 1975 |
Mechanism of quasi-morphine withdrawal behaviour induced by methylxanthines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Caffeine; Humans; | 1979 |
Effect of cyclic nucleotides and phosphodiesterase inhibition on morphine tolerance and physical dependence.
Topics: Adrenergic beta-Antagonists; Animals; Cyclic AMP; Cyclic GMP; Cycloheximide; Drug Tolerance; Humans; | 1975 |
Caffeine and theophylline as adenosine receptor antagonists in humans.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Caffeine; Heart Rate; Humans; Male; Platelet Ag | 1991 |
Do-Do abuse.
Topics: Adult; Antitussive Agents; Caffeine; Drug Combinations; Ephedrine; Female; Humans; Male; Middle Aged | 1990 |
Attenuation of isobutylmethylxanthine-induced suppression of operant behavior by pretreatment of rats with clonidine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Clonidine; Conditioning, Operant; Male; Narcotics; Rats; Rats, | 1987 |
Morphine blocks and naloxone enhances suppression of operant behavior by low doses of 3-isobutyl-1-methylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Body Temperature; Conditioning, Operant; Dose-Response Relatio | 1989 |
An improved protocol for the use of troleandomycin (TAO) in the treatment of steroid-requiring asthma.
Topics: Adult; Aged; Asthma; Bronchospirometry; Drug Administration Schedule; Female; Follow-Up Studies; Hum | 1986 |
Lack of effect of withdrawal from cigarette smoking on theophylline pharmacokinetics.
Topics: Adult; Humans; Liver; Male; Models, Biological; Smoking; Substance Withdrawal Syndrome; Theophylline | 1987 |
Cigarette abstinence, nicotine gum, and theophylline disposition.
Topics: Adult; Chewing Gum; Drug Interactions; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Age | 1987 |
Effect of cyclic AMP on morphine analgesia tolerance and physical dependence.
Topics: Analgesia; Animals; Cyclic AMP; Drug Tolerance; Humans; Male; Mice; Mice, Inbred Strains; Morphine; | 1972 |
The concept of the quasi-abstinence effect and its use in the investigation of dependence mechanisms.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Hormones; Humans; Naloxone; Phosphodiesterase | 1974 |
Proceedings: Cyclic nucleotides and ethanol withdrawal head-twitches in mice.
Topics: Animals; Bucladesine; Cyclic GMP; Ethanol; Head; Humans; Imidazoles; Methyltyrosines; Mice; Mice, In | 1974 |
Anxiety or caffeinism: a diagnostic dilemma.
Topics: Adult; Anxiety Disorders; Cacao; Caffeine; Carbonated Beverages; Coffee; Diagnosis, Differential; Do | 1974 |
Quasi morphine-abstinence syndrome.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Delayed-Action Preparations; Disease Models, Animal; | 1974 |