theophylline has been researched along with Drop Attack in 23 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, both acute electrophysiologic actions of intravenously administered theophylline and clinical effects of chronic oral theophylline therapy were assessed in 10 young patients (aged 9 to 41 years) without clinically significant cardiac disease, in whom recurrent symptoms of syncope and dizziness were attributed to transient bradyarrhythmias (sinus pauses, marked sinus bradycardia or paroxysmal atrioventricular [AV] block)." | 9.05 | Electrophysiologic effects of theophylline in young patients with recurrent symptomatic bradyarrhythmias. ( Benditt, DG; Benson, DW; Crouse, L; Dunnigan, A; Kreitt, J; Pritzker, MR; Scheinman, MM, 1983) |
| "Theophylline was effective in preventing recurrences in patients with syncope without prodromes, normal heart, and normal ECG." | 8.12 | Theophylline in patients with syncope without prodrome, normal heart, and normal electrocardiogram: a propensity-score matched study verified by implantable cardiac monitor. ( Brignole, M; Carretta, D; Deharo, JC; Guieu, R; Iori, M; Napoli, P; Rivasi, G; Solari, D; Strano, S; Tomaino, M; Ungar, A, 2022) |
| "In a consecutive case-series of 16 patients (mean age 47 ± 25 years, 9 females) who had ECG documentation of asystolic syncope, we compared the incidence of syncopal recurrence during a period without and a period with tailored theophylline therapy." | 7.91 | Efficacy of theophylline in patients with syncope without prodromes with normal heart and normal ECG. ( Bottoni, N; Brignole, M; Deharo, JC; Guieu, R; Iori, M; Rivasi, G; Solari, D; Ungar, A, 2019) |
| "In patients with symptomatic SSS, therapy with theophylline or dual-chamber pacemaker is associated with a lower incidence of heart failure; pacemaker therapy is also associated with a lower incidence of syncope." | 5.08 | Effects of permanent pacemaker and oral theophylline in sick sinus syndrome the THEOPACE study: a randomized controlled trial. ( Alboni, P; Brignole, M; Cappato, R; Gaggioli, G; Lolli, G; Menozzi, C; Paparella, N, 1997) |
| "To study the efficacy of medical treatment for preventing syncopal recurrences in patients affected by tilt-induced neurally mediated syncope, a randomized placebo-treatment prospective study was performed in 30 patients (10 men and 20 women, mean age 42 +/- 21 years) who had syncope reproduced in 2 consecutive head-up tilt-table tests without pharmacologic intervention (n = 20) or during isoproterenol infusion (n = 10)." | 5.07 | A controlled trial of acute and long-term medical therapy in tilt-induced neurally mediated syncope. ( Bottoni, N; Brignole, M; Gianfranchi, L; Lolli, G; Menozzi, C; Oddone, D, 1992) |
| "In this study, both acute electrophysiologic actions of intravenously administered theophylline and clinical effects of chronic oral theophylline therapy were assessed in 10 young patients (aged 9 to 41 years) without clinically significant cardiac disease, in whom recurrent symptoms of syncope and dizziness were attributed to transient bradyarrhythmias (sinus pauses, marked sinus bradycardia or paroxysmal atrioventricular [AV] block)." | 5.05 | Electrophysiologic effects of theophylline in young patients with recurrent symptomatic bradyarrhythmias. ( Benditt, DG; Benson, DW; Crouse, L; Dunnigan, A; Kreitt, J; Pritzker, MR; Scheinman, MM, 1983) |
| "Theophylline was effective in preventing recurrences in patients with syncope without prodromes, normal heart, and normal ECG." | 4.12 | Theophylline in patients with syncope without prodrome, normal heart, and normal electrocardiogram: a propensity-score matched study verified by implantable cardiac monitor. ( Brignole, M; Carretta, D; Deharo, JC; Guieu, R; Iori, M; Napoli, P; Rivasi, G; Solari, D; Strano, S; Tomaino, M; Ungar, A, 2022) |
| "In a consecutive case-series of 16 patients (mean age 47 ± 25 years, 9 females) who had ECG documentation of asystolic syncope, we compared the incidence of syncopal recurrence during a period without and a period with tailored theophylline therapy." | 3.91 | Efficacy of theophylline in patients with syncope without prodromes with normal heart and normal ECG. ( Bottoni, N; Brignole, M; Deharo, JC; Guieu, R; Iori, M; Rivasi, G; Solari, D; Ungar, A, 2019) |
| "The purpose of this study was to gain insight into the mechanism of vasovagal syncope and to test the efficacy of theophylline to prevent syncope." | 3.69 | Excessive myocardial contraction in vasovagal syncope demonstrated by echocardiography during head-up tilt test. ( Chao, CL; Chen, MF; Lee, TM; Lee, YT; Liau, CS; Su, SF, 1996) |
| "If cardiac syncope is unlikely, reflex (neurally mediated) syncope and orthostatic hypotension are the most frequent causes of transient loss of consciousness." | 2.72 | New insights in diagnostics and therapies in syncope: a novel approach to non-cardiac syncope. ( Brignole, M; Rivasi, G, 2021) |
| "The underlying etiology of a syncopal episode remains not infrequently unknown despite intensive and sometimes costly diagnostic procedures." | 2.39 | [Neurocardiac syncope: pathophysiology, diagnosis, therapy]. ( Hohnloser, SH; Klingenheben, T, 1995) |
| " In our case, the theophylline dosage was approximately half the amount described in previous reports." | 1.62 | Severe pallid breath-holding spells treated with low-dose theophylline. ( Asakai, H; Oda, Y; Sato, A, 2021) |
| "No further syncope has occurred for 16 months during the therapy with theophyllin." | 1.29 | [Pre-syncope and syncope at the operating table--diagnostic and therapeutic possibilities]. ( Heck, KF; Hust, MH; Keim, MW, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.70) | 18.7374 |
| 1990's | 9 (39.13) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 3 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Brignole, M | 7 |
| Iori, M | 4 |
| Strano, S | 1 |
| Tomaino, M | 2 |
| Rivasi, G | 3 |
| Ungar, A | 3 |
| Carretta, D | 1 |
| Solari, D | 3 |
| Napoli, P | 1 |
| Deharo, JC | 3 |
| Guieu, R | 4 |
| Sato, A | 1 |
| Oda, Y | 1 |
| Asakai, H | 1 |
| Bottoni, N | 4 |
| Mitro, P | 1 |
| Carano, N | 1 |
| Bo, I | 1 |
| Zanetti, E | 1 |
| Tchana, B | 1 |
| Barbato, G | 1 |
| Agnetti, A | 1 |
| Vallurupalli, S | 1 |
| Aggarwal, C | 1 |
| Sewani, A | 1 |
| Paydak, H | 1 |
| Treseder, JR | 1 |
| Jung, S | 1 |
| La Rocca, R | 1 |
| Campedel, F | 1 |
| Materia, V | 1 |
| Saggese, MP | 1 |
| Patanè, S | 1 |
| Bertolone, C | 1 |
| Unterhuber, M | 1 |
| Tesi, F | 1 |
| Claude Deharo, J | 1 |
| BREATHNACH, CS | 1 |
| Park, HW | 1 |
| Cho, JG | 1 |
| Yum, JH | 1 |
| Hong, YJ | 1 |
| Lim, JH | 1 |
| Kim, HG | 1 |
| Kim, JH | 1 |
| Ahn, YK | 1 |
| Jeong, MH | 1 |
| Park, JC | 1 |
| Kang, JC | 1 |
| Benditt, DG | 1 |
| Benson, DW | 1 |
| Kreitt, J | 1 |
| Dunnigan, A | 1 |
| Pritzker, MR | 1 |
| Crouse, L | 1 |
| Scheinman, MM | 1 |
| Natale, A | 1 |
| Sra, J | 1 |
| Dhala, A | 2 |
| Wase, A | 1 |
| Jazayeri, M | 1 |
| Deshpande, S | 2 |
| Blanck, Z | 2 |
| Akhtar, M | 2 |
| Klingenheben, T | 1 |
| Hohnloser, SH | 1 |
| Sra, JS | 1 |
| Jazayeri, MR | 1 |
| Avitall, B | 1 |
| Keim, MW | 1 |
| Heck, KF | 1 |
| Hust, MH | 1 |
| Grubb, BP | 1 |
| Kosinski, D | 1 |
| Mouhaffel, A | 1 |
| Pothoulakis, A | 1 |
| Lee, TM | 1 |
| Chen, MF | 1 |
| Su, SF | 1 |
| Chao, CL | 1 |
| Liau, CS | 1 |
| Lee, YT | 1 |
| Alboni, P | 1 |
| Menozzi, C | 2 |
| Paparella, N | 1 |
| Gaggioli, G | 1 |
| Lolli, G | 2 |
| Cappato, R | 1 |
| Gianfranchi, L | 1 |
| Oddone, D | 1 |
| Nelson, SD | 1 |
| Stanley, M | 1 |
| Love, CJ | 1 |
| Coyne, KS | 1 |
| Schaal, SF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Theophylline in Patients With Unexplained Syncope and Low Adenosine. Study Verified by ICM, Controlled by Propensity-score Matching[NCT03803215] | 77 participants (Actual) | Observational | 2016-05-11 | Completed | |||
| Assessment of the Mechanism of Non-cardiac Syncope by 24-hour Ambulatory Blood Pressure Monitoring (ABPM) and Tilt-table Short Cardiovascular Autonomic Function Battery (SCAFB)[NCT05728255] | 275 participants (Anticipated) | Observational | 2023-04-30 | Not yet recruiting | |||
| Efficacy of Transcatheter Ablation of Ganglionic Plexuses (Cardioneuroablation) in Right Atrium in Patients With Asystolic Neuromediated Syncope[NCT05751330] | 24 participants (Anticipated) | Interventional | 2022-09-20 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for theophylline and Drop Attack
| Article | Year |
|---|---|
New insights in diagnostics and therapies in syncope: a novel approach to non-cardiac syncope.
Topics: Accidental Falls; Adenosine; Antihypertensive Agents; Atomoxetine Hydrochloride; Atrioventricular No | 2021 |
[Neurocardiac syncope: pathophysiology, diagnosis, therapy].
Topics: Adrenergic beta-Antagonists; Autonomic Nervous System; Diagnosis, Differential; Heart; Hemodynamics; | 1995 |
4 trials available for theophylline and Drop Attack
| Article | Year |
|---|---|
Electrophysiologic effects of theophylline in young patients with recurrent symptomatic bradyarrhythmias.
Topics: Adolescent; Adult; Atrioventricular Node; Bradycardia; Cardiac Pacing, Artificial; Clinical Trials a | 1983 |
Efficacy of different treatment strategies for neurocardiogenic syncope.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Disopyramide; Ephedrine; Fe | 1995 |
Effects of permanent pacemaker and oral theophylline in sick sinus syndrome the THEOPACE study: a randomized controlled trial.
Topics: Administration, Oral; Aged; Atrial Fibrillation; Cardiac Output, Low; Female; Follow-Up Studies; Hea | 1997 |
A controlled trial of acute and long-term medical therapy in tilt-induced neurally mediated syncope.
Topics: Adult; Atenolol; Bandages; Dihydroergotamine; Domperidone; Female; Humans; Isoproterenol; Male; Midd | 1992 |
17 other studies available for theophylline and Drop Attack
| Article | Year |
|---|---|
Theophylline in patients with syncope without prodrome, normal heart, and normal electrocardiogram: a propensity-score matched study verified by implantable cardiac monitor.
Topics: Atrioventricular Block; Electrocardiography; Heart Arrest; Humans; Propensity Score; Recurrence; Syn | 2022 |
Severe pallid breath-holding spells treated with low-dose theophylline.
Topics: Apnea; Breath Holding; Dose-Response Relationship, Drug; Heart Arrest; Humans; Infant; Male; Seizure | 2021 |
Efficacy of theophylline in patients with syncope without prodromes with normal heart and normal ECG.
Topics: Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Child; Dose-Response Relationship | 2019 |
Asystolic syncope - To pace or not to pace, that is the question.
Topics: Electrocardiography; Heart Arrest; Humans; Syncope; Theophylline | 2019 |
Glycopyrrolate and theophylline for the treatment of severe pallid breath-holding spells.
Topics: Apnea; Breath Holding; Female; Glycopyrrolate; Humans; Infant; Muscarinic Antagonists; Phosphodieste | 2013 |
Oral theophylline as temporizing treatment of neck mass induced carotid sinus syncope.
Topics: Administration, Oral; Head and Neck Neoplasms; Humans; Male; Middle Aged; Syncope; Theophylline; Tre | 2013 |
Efficacy of theophylline in patients affected by low adenosine syncope.
Topics: Adenosine; Adult; Aged; Dose-Response Relationship, Drug; Electrocardiography; Female; Follow-Up Stu | 2016 |
ECG of the Month.
Topics: Animals; Dog Diseases; Dogs; Electrocardiography; Female; Pacemaker, Artificial; Sick Sinus Syndrome | 2016 |
Theophylline and syncope.
Topics: Adult; Atrioventricular Block; Bradycardia; Electrocardiography; Heart Rate; Humans; Male; Purinergi | 2016 |
Mechanism of syncope without prodromes with normal heart and normal electrocardiogram.
Topics: Aged; Atrioventricular Block; Cardiac Pacing, Artificial; Electrocardiography, Ambulatory; Female; H | 2017 |
COUGH SYNCOPE--THE MECHANISM IN TWO CASES.
Topics: Cough; Humans; Syncope; Theophylline; Toxicology | 1964 |
Clinical characteristics of hypervagotonic sinus node dysfunction.
Topics: Dizziness; Dyspnea; Female; Humans; Male; Middle Aged; Muscle Weakness; Sick Sinus Syndrome; Syncope | 2004 |
Comparison of cardiac pacing with drug therapy in the treatment of neurocardiogenic (vasovagal) syncope with bradycardia or asystole.
Topics: Adolescent; Adult; Aged; Bradycardia; Cardiac Pacing, Artificial; Disopyramide; Female; Follow-Up St | 1993 |
[Pre-syncope and syncope at the operating table--diagnostic and therapeutic possibilities].
Topics: Adult; Diagnosis, Differential; General Surgery; Humans; Male; Occupational Diseases; Syncope; Theop | 1996 |
The use of methylphenidate in the treatment of refractory neurocardiogenic syncope.
Topics: Administration, Oral; Adolescent; Adrenergic beta-Antagonists; Adult; Bradycardia; Central Nervous S | 1996 |
Excessive myocardial contraction in vasovagal syncope demonstrated by echocardiography during head-up tilt test.
Topics: Adrenergic beta-Agonists; Adult; Aged; Analysis of Variance; Echocardiography; Female; Humans; Isopr | 1996 |
The autonomic and hemodynamic effects of oral theophylline in patients with vasodepressor syncope.
Topics: Administration, Oral; Adult; Autonomic Nervous System; Bradycardia; Female; Heart; Heart Rate; Human | 1991 |