theophylline has been researched along with Down Syndrome in 2 studies
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stowe, CD | 1 |
| Phelps, SJ | 1 |
| Feichtinger, P | 1 |
| Frühmann, E | 1 |
| Rett, A | 1 |
2 other studies available for theophylline and Down Syndrome
| Article | Year |
|---|---|
Altered clearance of theophylline in children with Down syndrome: a case series.
Topics: Down Syndrome; Female; Humans; Infant; Male; Metabolic Clearance Rate; Retrospective Studies; Theoph | 1999 |
[Clinical and psychological studies on the effect of vascular and metabolic active substances on the cerebral circulation in children with brain damage].
Topics: Adolescent; Amines; Benzoates; Brain Damage, Chronic; Catechols; Cerebrovascular Circulation; Child; | 1969 |