theophylline and Diabetes Mellitus studies

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

Excerpt	Relevance	Reference
" In (a) 16 obese patients before and during therapeutic starvation, (b) 18 diabetics before and after antidiabetic treatment and (c) 11 hyperthyroid patients before and after anti-thyroid treatment, a positive correlation was found between stimulation of basal cyclic AMP accumulation and stimulation of basal glycerol release using either isopropyl noradrenaline or noradrenaline (r = 0."	3.66	Post receptor activation of lipolysis in starvation, diabetes mellitus and hyperthyroidism. ( Arner, P; Engfeldt, P; Ostman, J; Wennlund, A, 1981)
" Percent changes in venous pCO2 and pO2 were used as parameters of the pharmacodynamic action."	1.27	[Pharmacokinetics and pharmacodynamics of theophylline in geriatric patients with multiple diseases]. ( Bauer, M; Mühlberg, W; Platt, D; Salzner, U, 1987)
"Low PRA in diabetic nephropathy with slightly to moderately impaired renal function may not be due to hyaline destruction of the arteriolar walls, but to other factors such as sympathetic nervous dysfunction."	1.26	Renin-angiotensin-aldosterone system in mild diabetic nephropathy. ( Ideura, T; Matsuda, O; Shiigai, T; Takeuchi, J; Tomita, K, 1982)
" Based on the difference in dose-response curves between normal and insulin-deficient rats, a possibility is discussed that there are two adenylate cylase in the liver with higher and lower affinities for epinephrine and that circulating insulin blocks the high affinity enzyme selectively."	1.26	Attenuation of epinephrine-induced increase in liver cyclic AMP by endogeneous insulin in vivo. ( Shikama, H; Ui, M, 1976)

Timeframe	Studies, this research(%)	All Research%
pre-1990	42 (89.36)	18.7374
1990's	1 (2.13)	18.2507
2000's	2 (4.26)	29.6817
2010's	2 (4.26)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Srivastava, D	1
Fatima, Z	1
Kaur, CD	1
Bojko, B	1
Sułkowska, A	1
Maciazek-Jurczyk, M	1
Równicka, J	1
Sułkowski, WW	1
Kapoor, A	1
Kumar, S	1
Gulati, S	1
Gambhir, S	1
Sethi, RS	1
Sinha, N	1
BANSE, HJ	1
ZAHNOW, W	1
Pucelikova, T	1
Dangas, G	1
Mehran, R	1
Borsey, DQ	1
Dawes, J	1
Fraser, DM	1
Prowse, CV	1
Elton, RA	1
Clarke, BF	1
Arner, P	1
Engfeldt, P	1
Wennlund, A	1
Ostman, J	1
Tomita, K	1
Matsuda, O	1
Ideura, T	1
Shiigai, T	1
Takeuchi, J	1
Garber, AJ	1
Karl, IE	1
Kipnis, DM	1
Hayashi, S	1
Sakaguchi, T	1
Tutwiler, GF	1
Kirsch, TJ	1
Shikama, H	1
Ui, M	1
Schimmel, RJ	1
Edén, S	1
Albertsson-Wikland, K	1
Rosberg, S	1
Isaksson, O	1
Dehaye, JP	1
Winand, J	1
Poloczek, P	1
Christophe, J	1
Feinglos, MN	1
Drezner, MK	1
Lebovitz, HE	1
Volpe, JJ	1
Marasa, JC	1
Haacke, H	1
Parwaresch, MR	1
Rube, O	1
Mäder, C	1
Hahn, HJ	1
Schäfer, H	1
Gottschling, HD	1
Fiedler, H	1
Studlar, M	1
Pichler, O	1
Frankel, BJ	3
Gerich, JE	2
Fanska, RE	2
Gerritsen, GC	3
Grodsky, GM	3
Farkas, G	1
Lázár, G	1
Herczegh, J	1
Mühlberg, W	1
Platt, D	1
Bauer, M	1
Salzner, U	1
Nuzov, BG	1
Boquist, L	1
Hellman, B	2
Lernmark, A	2
Täljedal, IB	2
Gerich, KE	1
Loge, O	1
Losert, W	1
Jahn, P	1
Goldberg, ND	1
Dietz, SB	1
O'Toole, AG	1
Steinmetz, J	1
Lowry, L	1
Yen, TT	2
Earley, LE	1
Pilkis, SJ	1
Exton, JH	1
Johnson, RA	1
Park, CR	1
Nepokroeff, CM	1
Lakshmanan, MR	1
Ness, GC	1
Dugan, RE	1
Porter, JW	1
Iwatsuka, H	1
Taketomi, S	1
Matsuo, T	1
Suzuoki, Z	1
Gutzeit, A	1
Rabinovitch, A	1
Karakash, C	1
Stauffacher, W	1
Renold, AE	1
Cerasi, E	2
Schatz, H	1
Engel, K	1
Pramer, I	1
Atkins, T	1
Matty, AJ	1
Sehlin, J	1
Steinmetz, JA	1
Furuta, K	1
Hagura, R	1
Luft, R	1
Berezovsky, MR	1
Berstein, S	1
Lopez Morillas, AM	1
Novoa, FC	1
Acuña, E	1
Reitich, GE	1
Gottlieb, S	1
Malaisse, WJ	1
Malaisse-Lagae, F	1
Coleman, DL	1
Judick, V	1
Sachsse, B	1
Van Cauwenberge, H	1
Lefebvre, P	1
Luyckx, A	1
Hahn, J	1
Kaffarnik, H	1

Trial	Enrollment	Study Type	Start Date	Status
Pre-existing Microalbuminuria Predicting Contrast-induced Acute Kidney Injury (CIAKI) Following Coronary Angiography (CAG)[NCT02808845]	800 participants (Anticipated)	Observational	2016-12-31	Not yet recruiting
Early Detection of Contrast Induced Nephropathy After Coronary Angiography : Predictive Value of Osteopontin[NCT05547581]	155 participants (Anticipated)	Observational	2022-12-07	Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Multicomponent Pharmaceutical Cocrystals: A Novel Approach for Combination Therapy. Mini reviews in medicinal chemistry, 2018, Volume: 18, Issue:14 Topics: Asthma; Chemistry, Pharmaceutical; Crystallization; Diabetes Mellitus; Drug Therapy, Combination; Fl	2018
Contrast-induced nephropathy. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, Jan-01, Volume: 71, Issue:1 Topics: Acetylcysteine; Acute Kidney Injury; Calcium Channel Blockers; Contrast Media; Coronary Angiography;	2008
Contrast-induced nephropathy. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, Jan-01, Volume: 71, Issue:1 Topics: Acetylcysteine; Acute Kidney Injury; Calcium Channel Blockers; Contrast Media; Coronary Angiography;	2008
Contrast-induced nephropathy. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, Jan-01, Volume: 71, Issue:1 Topics: Acetylcysteine; Acute Kidney Injury; Calcium Channel Blockers; Contrast Media; Coronary Angiography;	2008
Contrast-induced nephropathy. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, Jan-01, Volume: 71, Issue:1 Topics: Acetylcysteine; Acute Kidney Injury; Calcium Channel Blockers; Contrast Media; Coronary Angiography;	2008

Article	Year
The influence of dietary habits and pathological conditions on the binding of theophylline to serum albumin. Journal of pharmaceutical and biomedical analysis, 2010, Jul-08, Volume: 52, Issue:3 Topics: Binding Sites; Diabetes Mellitus; Fatty Acids; Feeding Behavior; Humans; Kinetics; Nuclear Magnetic	2010
[New medicinal treatment possibilities of angiopathy in diabetics with 3-(methyloxyethylamino)-2-oxyprophyltheophylline nicotinate (complamin)]. Munchener medizinische Wochenschrift (1950), 1958, Dec-26, Volume: 100, Issue:52 Topics: Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Niacin; Nicotinic Acids; Theophy	1958
Plasma beta-thromboglobulin in diabetes mellitus. Diabetologia, 1980, Volume: 18, Issue:5 Topics: Adult; Anticoagulants; Beta-Globulins; beta-Thromboglobulin; Diabetes Mellitus; Diabetic Angiopathie	1980
Post receptor activation of lipolysis in starvation, diabetes mellitus and hyperthyroidism. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1981, Volume: 13, Issue:5 Topics: Adult; Catecholamines; Cyclic AMP; Diabetes Mellitus; Female; Glycerol; Humans; Hyperthyroidism; Lip	1981
Renin-angiotensin-aldosterone system in mild diabetic nephropathy. Nephron, 1982, Volume: 31, Issue:4 Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Blood Vessels; Diabetes Mellitus; Diabetic Nep	1982
Alanine and glutamine synthesis and release from skeletal muscle. IV. beta-Adrenergic inhibition of amino acid release. The Journal of biological chemistry, 1976, Feb-10, Volume: 251, Issue:3 Topics: Alanine; Animals; Bucladesine; Cortisone; Diabetes Mellitus; Epinephrine; Glucagon; Glutamine; In Vi	1976
Effects of epinephrine and theophylline on lipolytic response in hereditary diabetic mice. The Tohoku journal of experimental medicine, 1976, Volume: 119, Issue:1 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus; Drug	1976
Noncyclic AMP-mediated lipolytic effect of bovine and porcine diabetogenic proteins. Biochemical medicine, 1976, Volume: 15, Issue:2 Topics: Adipose Tissue; Animals; Bucladesine; Cattle; Cyclic AMP; Diabetes Mellitus; Epinephrine; Glucagon;	1976
Attenuation of epinephrine-induced increase in liver cyclic AMP by endogeneous insulin in vivo. Biochimica et biophysica acta, 1976, Sep-24, Volume: 444, Issue:2 Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Cyclic AMP;	1976
Adenosine 3',5'cyclic monophosphate in adipose tissue of diabetic rats. Biochimica et biophysica acta, 1976, Dec-21, Volume: 451, Issue:2 Topics: Adipose Tissue; Animals; Blood Glucose; Cyclic AMP; Diabetes Mellitus; Diabetes Mellitus, Experiment	1976
Effect of insulin and adrenaline on cyclic AMP in the diaphragm of normal and diabetic rats. Acta endocrinologica, 1977, Volume: 85, Issue:4 Topics: Animals; Cyclic AMP; Diabetes Mellitus; Diaphragm; Epinephrine; Female; Insulin; Muscles; Rats; Theo	1977
Relationship between lipolysis and calcium in epididymal adipose tissue of obese-hyperglycaemic mice. Diabetologia, 1979, Volume: 16, Issue:6 Topics: Adenosine Triphosphate; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Bucladesine; Calcium;	1979
Measurement of plasma adenosine 3',5'-monophosphate. The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:5 Topics: Animals; Binding, Competitive; Chemical Precipitation; Cyclic AMP; Diabetes Mellitus; Edetic Acid; H	1978
Hormonal regulation of fatty acid synthetase, acetyl-CoA carboxylase and fatty acid synthesis in mammalian adipose tissue and liver. Biochimica et biophysica acta, 1975, Mar-24, Volume: 380, Issue:3 Topics: Acetyl-CoA Carboxylase; Adipose Tissue; Adrenalectomy; Animals; Diabetes Mellitus; Fatty Acid Syntha	1975
[Effect of lipid-lowering treatment with xanthinol-nicotinate on the carbohydrate metabolism in mature-onset diabetics and non-diabetic patients with hyperlipoproteinemias (HLP)]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84 Topics: Carbohydrate Metabolism; Diabetes Mellitus; Fatty Acids, Nonesterified; Humans; Hyperlipidemias; The	1978
Insulin and glucagon secretion by pancreatic islets from nondiabetic and diabetic sand rats (Psammomys obesus). European journal of clinical investigation, 1976, Jan-30, Volume: 6, Issue:1 Topics: Animals; Body Weight; Diabetes Mellitus; Female; Glucagon; Glucose; Glyceraldehyde; In Vitro Techniq	1976
[Metabolism studies with coffee and caffeine in healthy subjects, diabetics and patients with liver disease]. Zeitschrift fur Ernahrungswissenschaft, 1976, Volume: 15, Issue:1 Topics: Caffeine; Coffee; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucose; Humans; Insulin; Liver Dis	1976
Responses to arginine of the perfused pancreas of the genetically diabetic Chinese hamster. Diabetes, 1975, Volume: 24, Issue:3 Topics: Animals; Arginine; Cattle; Cricetinae; Depression, Chemical; Diabetes Mellitus; Drug Interactions; F	1975
The long-term cultivation and cryopreservation of human fetal pancreatic tissue. Hormone and metabolic research. Supplement series, 1990, Volume: 25 Topics: Cryopreservation; Diabetes Mellitus; Fetal Tissue Transplantation; Glucose; Humans; Insulin; Insulin	1990
[Pharmacokinetics and pharmacodynamics of theophylline in geriatric patients with multiple diseases]. Klinische Wochenschrift, 1987, Jul-15, Volume: 65, Issue:12 Topics: Age Factors; Aged; Carbon Dioxide; Diabetes Complications; Diabetes Mellitus; Female; Half-Life; Hea	1987
[Use of teonikol and trental in the combined treatment of patients with suppurative surgical infection and concomitant diabetes mellitus]. Klinicheskaia meditsina, 1985, Volume: 63, Issue:12 Topics: Chronic Disease; Conjunctiva; Diabetes Mellitus; Drug Therapy, Combination; Female; Hemodynamics; Hu	1985
Influence of the mutation "diabetes" on insulin release and islet morphology in mice of different genetic backgrounds. The Journal of cell biology, 1974, Volume: 62, Issue:1 Topics: Animals; Benzenesulfonates; Blood Glucose; Body Weight; Diabetes Mellitus; Glucose; Hyperglycemia; I	1974
The diabetic Chinese hamster: in vitro insulin and glucagon release; the ""chemical diabetic";; and the effect of diet on ketonuria. Diabetologia, 1974, Volume: 10 Suppl Topics: Animals; Arginine; Cricetinae; Diabetes Mellitus; Diabetic Ketoacidosis; Disease Models, Animal; Fem	1974
[Influence on serum insulin concentration of sodium glymidine (glykodiazine), isopropylnorepinephrine, glucagon and theophylline in Chinese hamsters with spontaneous or streptozotocin-induced diabetes mellitus]. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1973, Jun-19, Volume: 160, Issue:4 Topics: Adenylyl Cyclases; Animals; Cricetinae; Diabetes Mellitus; Female; Glucagon; Insulin; Islets of Lang	1973
Cyclic guanosine 3',5'-monophosphate in mammalian tissues and urine. The Journal of biological chemistry, 1969, Aug-25, Volume: 244, Issue:16 Topics: Animals; Brain Chemistry; Chromatography, Thin Layer; Cyclic AMP; Diabetes Mellitus; Diabetes Mellit	1969
An analysis of the lipolysis in vitro of obese-hyperglycaemic and diabetic mice. Diabetologia, 1969, Volume: 5, Issue:6 Topics: Adenine Nucleotides; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Blood Glucose; Cyclic AMP	1969
Chlorpropamide antidiuresis. The New England journal of medicine, 1971, Jan-14, Volume: 284, Issue:2 Topics: Aged; Animals; Cell Membrane Permeability; Chlorpropamide; Cyclic AMP; Diabetes Insipidus; Diabetes	1971
Effects of glucagon on cyclic AMP and carbohydrate metabolism in livers from diabetic rats. Biochimica et biophysica acta, 1974, Mar-20, Volume: 343, Issue:1 Topics: Adenylyl Cyclases; Animals; Calcium; Carbohydrate Metabolism; Cell Membrane; Cyclic AMP; Diabetes Me	1974
Regulation of the diurnal rhythm of rat liver beta-hydroxy-beta-methylglutaryl coenzmye A reductase activity by insulin, glucagon, cyclic AMP and hydrocortisone. Archives of biochemistry and biophysics, 1974, Volume: 160, Issue:2 Topics: Alcohol Oxidoreductases; Animals; Bucladesine; Carbon Radioisotopes; Chromatography, Paper; Circadia	1974
Congenitally impaired hormone sensitivity of the adipose tissue of spontaneously diabetic mice, KK. Validity of thrifty genotype in KK mice. Diabetologia, 1974, Volume: 10 Suppl Topics: Adipose Tissue; Animals; Concanavalin A; Cyclic AMP; Diabetes Mellitus; Disease Models, Animal; Epin	1974
Evidence for decreased sensitivity to glucose of isolated islets from spiny mice. (Acomys cahirinus). Diabetologia, 1974, Volume: 10 Suppl Topics: Animals; Antigens; Arginine; Cyclic AMP; Cytochalasin B; Diabetes Mellitus; Disease Models, Animal;	1974
[The pancreatic beta-cell in the field of current diabetology]. Acta medica Austriaca, 1974, Volume: 3, Issue:1 Topics: Blood Glucose; Cyclic AMP; Diabetes Mellitus; Glucagon; Glucose Tolerance Test; Glyburide; Growth Ho	1974
[Possibility of improvement of cerebral function under the effect of prolonged combined infusions-injections oral therapy in geriatrics]. Wiener medizinische Wochenschrift (1946), 1971, Apr-03, Volume: 121, Issue:14 Topics: Administration, Oral; Aged; Attention; Benzamides; Benzoates; Blood Pressure; Catechols; Central Ner	1971
[Six years' experience with a musculoplastic technic]. The Journal of endocrinology, 1971, Volume: 51, Issue:1 Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists	1971
The pancreatic -cell recognition of insulin secretagogues. V. Binding and stimulatory action of phlorizin. Molecular pharmacology, 1972, Volume: 8, Issue:6 Topics: Animals; Antimycin A; Arginine; Carbon Isotopes; Chloromercuribenzoates; Chlorpromazine; Diabetes Me	1972
Lipolysis of genetically obese and-or hyperglycemic mice with reference to insulin response of adipose tissue. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1972, Volume: 4, Issue:5 Topics: Adipose Tissue; Animals; Diabetes Mellitus; Epididymis; Epinephrine; Fatty Acids, Nonesterified; Gen	1972
[Clinical-pathological investigation on retinal and cerebral hemodynamics]. Japanese circulation journal, 1972, Volume: 36, Issue:12 Topics: Adolescent; Adult; Age Factors; Aged; Amino Alcohols; Benzoates; Blood Pressure; Blood Volume; Cereb	1972
Abnormal secretion of insulin and glucagon by the in vitro perfused pancreas of the genetically diabetic Chinese hamster. The Journal of clinical investigation, 1974, Volume: 53, Issue:6 Topics: Animals; Blood Glucose; Cattle; Cricetinae; Diabetes Mellitus; Disease Models, Animal; Drug Combinat	1974
The pathogenesis of diabetes mellitus in man. Bulletin de l'Academie royale de medecine de Belgique, 1971, Volume: 11, Issue:4 Topics: Animals; Diabetes Mellitus; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Propr	1971
[Acute effect of xanthinol nicotinate on cutaneous and intramuscular temperature in diabetic patients]. Prensa medica argentina, 1971, Jul-02, Volume: 58, Issue:18 Topics: Adult; Aged; Body Temperature; Diabetes Mellitus; Diabetic Angiopathies; Female; Humans; Male; Middl	1971
Insulin secretion in mice with an hereditary diabetes. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 129, Issue:1 Topics: Aging; Animals; Blood Glucose; Diabetes Mellitus; Female; Glucose; Insulin; Insulin Secretion; Mice;	1968
[Influence of a nicotinic acid derivative on carbohydrate metabolism in the diabetic patient]. Medizinische Klinik, 1968, May-03, Volume: 63, Issue:18 Topics: Aged; Blood Glucose; Carbohydrate Metabolism; Circadian Rhythm; Diabetes Mellitus; Furosemide; Glyco	1968
[The determination of pancreatic hormones. Clinical and experimental uses]. Bulletin de l'Academie royale de medecine de Belgique, 1968, Volume: 8, Issue:11 Topics: Animals; Diabetes Mellitus; Dogs; Fatty Acids; Glucagon; Glucose; Humans; Insulin; Pancreas; Theophy	1968
[Influence of therapy and adjustment of diabetics with xanthine nicotinate]. Medizinische Klinik, 1969, May-30, Volume: 64, Issue:22 Topics: Aged; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glycosuria; Humans; Hypo	1969

theophylline and Diabetes Mellitus

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