Page last updated: 2024-10-22

theophylline and Delayed Hypersensitivity

theophylline has been researched along with Delayed Hypersensitivity in 9 studies

Research Excerpts

Excerpt	Relevance	Reference
", theophylline) can have a prophylactic effect on natural or experimentally induced asthma by maintaining high levels of cyclic AMP in the target organ cells."	5.04	Pharmacologic modification of induced asthma. ( Falliers, CJ; Katsampes, CF, 1976)
" tuberculosis proposed by the authors implies conduction of leukocyte migration inhibition test under theophylline-induced block of T-suppressor function."	3.68	[New test for detection of hypersensitivity to mycobacterial tuberculosis]. ( Batian, AN; Batian, ON; Titov, LP, 1993)

Trial	Phase	Enrollment	Study Type	Start Date	Status
Does a Lipophilic Steroid Inhaled After an Early Allergic Reaction Affect the Late Reaction?[NCT00716963]	Phase 4	7 participants (Actual)	Interventional	2008-07-31	Completed
Kinetics of IgE Memory B Cells, Plasmablasts and Plasma Cells After Whole Lung Allergen Challenge in Mild Asthmatics[NCT01420003]		12 participants (Actual)	Interventional	2011-11-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

(NCT00716963)
Timeframe: Before inhalation 3 hours

Intervention	percentage fall FEV1 (Mean)
Fluticasone Propionate (Flovent Diskus) 250 mcg	-30.5
Budesonide 400mcg	-39.0
Placebo	-31.9

(NCT00716963)
Timeframe: 7 hours after challenge

Intervention	percentage fall FEV1 (Mean)
Fluticasone Propionate (Flovent Diskus) 250 mcg	-11.6
Budesonide 400mcg	-14.7
Placebo	-24

3 reviews available for theophylline and Delayed Hypersensitivity

Article	Year
Physiologic changes that occur in response to allergen induced challenge. Clinical reviews in allergy, 1985, Volume: 3, Issue:4 Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aerosols; Allergens;	1985
Late asthmatic responses. The American review of respiratory disease, 1987, Volume: 136, Issue:3 Topics: Allergens; Animals; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Cyclooxygenase Inhibitors;	1987
Late asthmatic responses. The American review of respiratory disease, 1987, Volume: 136, Issue:3 Topics: Allergens; Animals; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Cyclooxygenase Inhibitors;	1987
Late asthmatic responses. The American review of respiratory disease, 1987, Volume: 136, Issue:3 Topics: Allergens; Animals; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Cyclooxygenase Inhibitors;	1987
Late asthmatic responses. The American review of respiratory disease, 1987, Volume: 136, Issue:3 Topics: Allergens; Animals; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Cyclooxygenase Inhibitors;	1987
Airway hyperresponsiveness and late asthmatic responses. Chest, 1988, Volume: 94, Issue:1 Topics: Adrenal Cortex Hormones; Allergens; Anti-Inflammatory Agents; Asthma; Bronchial Spasm; Cromolyn Sodi	1988

1 trial available for theophylline and Delayed Hypersensitivity

Article	Year
Pharmacologic modification of induced asthma. Annals of allergy, 1976, Volume: 36, Issue:2 Topics: Adult; Airway Resistance; Asthma; Clinical Trials as Topic; Cyclic AMP; Drug Synergism; Ephedrine; F	1976

5 other studies available for theophylline and Delayed Hypersensitivity

Article	Year
A comparison of late reactions to antigen and exercise. The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 2 Topics: Albuterol; Antigens; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Chemotactic Fact	1984
[On the inhibition of immediate and delayed type allergic skin reactions by the drugs elevating cellular cyclic AMP (author's transl)]. Nihon Ika Daigaku zasshi, 1981, Volume: 48, Issue:3 Topics: Animals; Bradykinin; Cyclic AMP; Drug Hypersensitivity; Female; Histamine; Hypersensitivity, Delayed	1981
[New test for detection of hypersensitivity to mycobacterial tuberculosis]. Problemy tuberkuleza, 1993, Issue:4 Topics: Adult; Aged; Cell Migration Inhibition; Female; Humans; Hypersensitivity, Delayed; Male; Middle Aged	1993
Delayed-type hypersensitivity to theophylline/aminophylline. Lancet (London, England), 1985, Jan-05, Volume: 1, Issue:8419 Topics: Aminophylline; Drug Eruptions; Humans; Hypersensitivity, Delayed; Theophylline	1985
[Clinico-immunological polymorphism of the hyperimmunoglobulinemia E syndrome]. Pediatriia, 1985, Issue:1 Topics: Adolescent; Chemotaxis, Leukocyte; Child; Child, Preschool; Chronic Disease; Female; Humans; Hyperga	1985