Page last updated: 2024-10-22

theophylline and Cystic Fibrosis

theophylline has been researched along with Cystic Fibrosis in 46 studies

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
"The sputum pharmacokinetics and clinical efficacy of ciprofloxacin in lower respiratory tract infections is reviewed."10.16Clinical efficacy of ciprofloxacin in lower respiratory tract infections. ( Pedersen, SS, 1989)
"The effect of theophylline (T) was studied in 12 children with cystic fibrosis (CF) (seven males and five females) aged 7 to 17 yr (mean, 11."9.07Effect of theophylline on lung function tests, sleep quality, and nighttime SaO2 in children with cystic fibrosis. ( Avital, A; Chernick, V; Holbrow, J; Kryger, M; Sanchez, I, 1991)
"Most patients with cystic fibrosis (CF) eventually develop chronic obstructive pulmonary disease and theoretically could benefit from theophylline therapy."9.06Bronchodilation from intravenous theophylline in patients with cystic fibrosis: results of a blinded placebo-controlled crossover clinical trial. ( Canafax, DM; Cipolle, RJ; Le, CT; Pan, SH; Uden, DL; Warwick, WJ, 1989)
"A study was designed to evaluate the reproducibility of right and left ventricular ejection fraction measurements (RVEF, LVEF) by equilibrium radionuclide angiography in cystic fibrosis (CF) and to determine the effect of the acute administration of aminophylline on RVEF and LVEF in this disease."9.05Radionuclide assessment of cardiac performance in cystic fibrosis. Reproducibility and effect of theophylline on cardiac function. ( Canny, GJ; de Souza, ME; Gilday, DL; Newth, CJ, 1984)
" The serum protein binding of theophylline was studied in 28 asthmatics and 11 patients with cystic fibrosis (CF) who were receiving the drug regularly."7.68Variability of the serum protein binding of theophylline in patients with asthma and cystic fibrosis. ( Blanchard, J; Harvey, S; Morgan, WJ, 1992)
"Theophylline levels in stimulated and unstimulated mixed saliva were compared with total and free (unbound) serum theophylline levels in 11 outpatients with cystic fibrosis (CF) who were using theophylline regularly."7.68Relationship between serum and saliva theophylline levels in patients with cystic fibrosis. ( Blanchard, J; Harvey, S; Morgan, WJ, 1992)
"Multiple aspects of lung function were measured in 17 cystic fibrosis (CF) patients on four occasions: without therapy (0); with oral theophylline medication (Th); after inhalation of salbutamol (beta 2); and with combined medication (Th + beta 2)."7.67Airway obstruction and airway wall instability in cystic fibrosis: the isolated and combined effect of theophylline and sympathomimetics. ( Eber, E; Oberwaldner, B; Zach, MS, 1988)
"The elimination of theophylline after intravenous aminophylline bolus and the absorption of a sustained-release oral theophylline preparation (Theo-Dur) were studied in ten patients with cystic fibrosis (C."7.66Pharmacokinetics of theophylline and bioavailability of a sustained release theophylline preparation in patients with cystic fibrosis. ( Brooks, JG; Schwartz, RH; Valet, SB, 1983)
"The disposition of intravenously and orally administered theophylline was compared in 10 patients with cystic fibrosis (CF) and 10 healthy volunteers."7.66Theophylline disposition in cystic fibrosis. ( Isles, A; Levison, H; MacLeod, S; Spino, M; Tabachnik, E; Thiessen, J, 1983)
"The sputum pharmacokinetics and clinical efficacy of ciprofloxacin in lower respiratory tract infections is reviewed."6.16Clinical efficacy of ciprofloxacin in lower respiratory tract infections. ( Pedersen, SS, 1989)
"The effect of theophylline (T) was studied in 12 children with cystic fibrosis (CF) (seven males and five females) aged 7 to 17 yr (mean, 11."5.07Effect of theophylline on lung function tests, sleep quality, and nighttime SaO2 in children with cystic fibrosis. ( Avital, A; Chernick, V; Holbrow, J; Kryger, M; Sanchez, I, 1991)
"Most patients with cystic fibrosis (CF) eventually develop chronic obstructive pulmonary disease and theoretically could benefit from theophylline therapy."5.06Bronchodilation from intravenous theophylline in patients with cystic fibrosis: results of a blinded placebo-controlled crossover clinical trial. ( Canafax, DM; Cipolle, RJ; Le, CT; Pan, SH; Uden, DL; Warwick, WJ, 1989)
"A study was designed to evaluate the reproducibility of right and left ventricular ejection fraction measurements (RVEF, LVEF) by equilibrium radionuclide angiography in cystic fibrosis (CF) and to determine the effect of the acute administration of aminophylline on RVEF and LVEF in this disease."5.05Radionuclide assessment of cardiac performance in cystic fibrosis. Reproducibility and effect of theophylline on cardiac function. ( Canny, GJ; de Souza, ME; Gilday, DL; Newth, CJ, 1984)
"This study examined the effect of aerosolized isoproterenol and oral theophylline on pulmonary function in cystic fibrosis (CF) to determine how often these drugs are beneficial and whether there is a correlation between response to isoproterenol and response to oral theophylline."5.04The paradoxical effect of adrenergic and methylxanthine drugs in cystic fibrosis. ( Bamman, J; Bierman, CW; Kanarek, P; Shapiro, GG, 1976)
" This review focuses on advances and controversies in the therapy of asthma, including issues regarding medications such as inhaled beta 2-agonists, inhaled corticosteroids, cromolyn sodium, and theophylline."4.78Advances in respiratory therapeutics in children. ( Reisman, JJ, 1993)
"Bicycle ergospirometry was performed on 14 patients with cystic fibrosis (CF), for evaluating the effects of salbutamol and theophylline on the ventilatory response to exercise."3.68Increased physiological dead space during exercise after bronchodilation in cystic fibrosis. ( Friedrichs, F; Heimann, G; Kusenbach, G; Skopnik, H, 1993)
" The serum protein binding of theophylline was studied in 28 asthmatics and 11 patients with cystic fibrosis (CF) who were receiving the drug regularly."3.68Variability of the serum protein binding of theophylline in patients with asthma and cystic fibrosis. ( Blanchard, J; Harvey, S; Morgan, WJ, 1992)
"Theophylline levels in stimulated and unstimulated mixed saliva were compared with total and free (unbound) serum theophylline levels in 11 outpatients with cystic fibrosis (CF) who were using theophylline regularly."3.68Relationship between serum and saliva theophylline levels in patients with cystic fibrosis. ( Blanchard, J; Harvey, S; Morgan, WJ, 1992)
"Multiple aspects of lung function were measured in 17 cystic fibrosis (CF) patients on four occasions: without therapy (0); with oral theophylline medication (Th); after inhalation of salbutamol (beta 2); and with combined medication (Th + beta 2)."3.67Airway obstruction and airway wall instability in cystic fibrosis: the isolated and combined effect of theophylline and sympathomimetics. ( Eber, E; Oberwaldner, B; Zach, MS, 1988)
"The elimination of theophylline after intravenous aminophylline bolus and the absorption of a sustained-release oral theophylline preparation (Theo-Dur) were studied in ten patients with cystic fibrosis (C."3.66Pharmacokinetics of theophylline and bioavailability of a sustained release theophylline preparation in patients with cystic fibrosis. ( Brooks, JG; Schwartz, RH; Valet, SB, 1983)
"The disposition of intravenously and orally administered theophylline was compared in 10 patients with cystic fibrosis (CF) and 10 healthy volunteers."3.66Theophylline disposition in cystic fibrosis. ( Isles, A; Levison, H; MacLeod, S; Spino, M; Tabachnik, E; Thiessen, J, 1983)
"Alkaline phosphatase (ALP) activities were compared in fibroblasts from three cystic fibrosis patients and two normal controls after culturing the cells in normal growth medium and in medium containing Tamm-Horsfall glycoprotein, isoproterenol, and theophylline."3.66Alkaline phosphatase activity of normal and cystic fibrosis fibroblasts. ( Aitken, DA; Hoogeveen, A, 1980)
"The specific induction of alkaline phosphatase with Tamm-Horsfall glycoprotein, isoproterenol, and theophylline in skin-derived fibroblast cultures from patients with cystic fibrosis permits one to reliably discriminate between cystic fibrosis patients on the one hand, and heterozygotes and normals on the other."3.66Reliable detection of cystic fibrosis in skin-derived fibroblast cultures. ( Hösli, P; Vogt, E, 1978)
" Although, in patients with CF, the extent of drug absorption varies widely and the rate of absorption is slower, bioavailability is not altered."2.40Drug disposition in cystic fibrosis. ( Pons, G; Rey, E; Tréluyer, JM, 1998)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199024 (52.17)18.7374
1990's15 (32.61)18.2507
2000's5 (10.87)29.6817
2010's2 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chung, WJ1
Goeckeler-Fried, JL1
Havasi, V1
Chiang, A1
Rowe, SM1
Plyler, ZE1
Hong, JS1
Mazur, M1
Piazza, GA1
Keeton, AB1
White, EL1
Rasmussen, L1
Weissman, AM1
Denny, RA1
Brodsky, JL1
Sorscher, EJ1
Goodwin, AT1
Singanayagam, A1
Jenkins, G1
Balfour-Lynn, IM2
Elborn, JS1
Buckley, SM1
Waddington, SN1
Jezzard, S1
Lawrence, L1
Schneider, H1
Holder, MV1
Themis, M1
Coutelle, C1
Canny, GJ1
de Souza, ME1
Gilday, DL1
Newth, CJ1
Anderson, SD1
Bukowskyj, M1
Nakatsu, K1
Munt, PW1
Morgan, WJ3
Taussig, LM1
Sato, K1
Sato, F1
Valet, SB1
Schwartz, RH1
Brooks, JG1
Isles, A1
Spino, M2
Tabachnik, E1
Levison, H1
Thiessen, J1
MacLeod, S1
Berger, HJ1
Matthay, RA1
Götz, M1
Georgitis, JW1
Eigen, H1
Warner, R1
Gonzales, MA1
Aitken, DA1
Hoogeveen, A1
Becq, F1
Fanjul, M1
Merten, M1
Figarella, C1
Hollande, E1
Gola, M1
Reisman, JJ1
Kusenbach, G1
Friedrichs, F1
Skopnik, H1
Heimann, G1
Kearns, GL1
Teune, TM1
Timmers-Reker, AJ1
Bouquet, J1
Bijman, J1
De Jonge, HR1
Sinaasappel, M1
Rey, E1
Tréluyer, JM1
Pons, G1
Self, TH1
Chafin, CC1
Soberman, JE1
McPherson, MA1
Pereira, MM1
Russell, D1
McNeilly, CM1
Morris, RM1
Stratford, FL1
Dormer, RL1
Hösli, P2
Kollberg, H1
Vogt, E2
Shapiro, GG1
Bamman, J1
Kanarek, P1
Bierman, CW1
Blanchard, J2
Harvey, S2
Sweet, A1
Erickson, RP1
Huntington, C1
Dawson, D1
O'Mahony, MS1
FitzGerald, MX1
Goldstein, JL2
Shapiro, AB1
Rao, MC2
Layden, TJ2
Jefferson, DM1
Valentich, JD1
Marini, FC1
Grubman, SA1
Iannuzzi, MC1
Dorkin, HL1
Li, M1
Klinger, KW1
Welsh, MJ1
Avital, A1
Sanchez, I1
Holbrow, J1
Kryger, M1
Chernick, V1
Taylor, DM1
Flowers, MK1
Squassoni, E1
Cabrini, G1
Berton, G1
Suter, S1
Chevallier, I1
Krause, KH1
Lew, DP1
Pan, SH1
Canafax, DM1
Le, CT1
Cipolle, RJ1
Uden, DL1
Warwick, WJ1
Pedersen, SS1
Berschneider, HM1
Knowles, MR1
Azizkhan, RG1
Boucher, RC1
Tobey, NA1
Orlando, RC1
Powell, DW1
Storm, W1
Knoppert, DC1
Beck, R1
Thiessen, JJ1
MacLeod, SM1
Nash, NT1
al-Bazzaz, F1
Eber, E1
Oberwaldner, B1
Zach, MS1
Mangos, JA1
Benke, PJ1
McSherry, N1
Richards, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00005279]0 participants Observational1971-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

12 reviews available for theophylline and Cystic Fibrosis

ArticleYear
"CF asthma": what is it and what do we do about it?
    Thorax, 2002, Volume: 57, Issue:8

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Bronchial Hyperreactivity; Bronchodila

2002
Asthma in cystic fibrosis.
    Journal of the Royal Society of Medicine, 2003, Volume: 96 Suppl 43

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Bronchodilator Agents; Chi

2003
Drugs affecting the respiratory system with particular reference to asthma.
    Medicine and science in sports and exercise, 1981, Volume: 13, Issue:4

    Topics: Adrenergic alpha-Antagonists; Asthma; Asthma, Exercise-Induced; Bronchi; Child; Cromolyn Sodium; Cys

1981
Theophylline reassessed.
    Annals of internal medicine, 1984, Volume: 101, Issue:1

    Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents;

1984
The chronic bronchitis complex in children.
    Pediatric clinics of North America, 1984, Volume: 31, Issue:4

    Topics: Adrenergic beta-Agonists; Adult; Age Factors; Air Pollution; Anti-Bacterial Agents; Asthma; Bronchit

1984
Noninvasive radiographic assessment of cardiovascular function in acute and chronic respiratory failure.
    The American journal of cardiology, 1981, Volume: 47, Issue:4

    Topics: Acute Disease; Aminophylline; Blood Pressure; Cardiovascular System; Chronic Disease; Cystic Fibrosi

1981
Advances in respiratory therapeutics in children.
    Current opinion in pediatrics, 1993, Volume: 5, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Inflammatory Agents; Asthma; Bronchiolitis,

1993
Hepatic drug metabolism in cystic fibrosis: recent developments and future directions.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:1

    Topics: Bile; Biotransformation; Child; Child, Preschool; Cystic Fibrosis; Fleroxacin; Humans; Liver; Liver

1993
Drug disposition in cystic fibrosis.
    Clinical pharmacokinetics, 1998, Volume: 35, Issue:4

    Topics: Absorption; Anti-Infective Agents; Ciprofloxacin; Cloxacillin; Cyclosporine; Cystic Fibrosis; Flerox

1998
Effect of disease states on theophylline serum concentrations: are we still vigilant?
    The American journal of the medical sciences, 2000, Volume: 319, Issue:3

    Topics: Cystic Fibrosis; Fever; Heart Failure; Humans; Liver Cirrhosis; Pulmonary Heart Disease; Theophyllin

2000
Clinical efficacy of ciprofloxacin in lower respiratory tract infections.
    Scandinavian journal of infectious diseases. Supplementum, 1989, Volume: 60

    Topics: Ciprofloxacin; Clinical Trials as Topic; Cystic Fibrosis; Drug Interactions; Humans; Lung Diseases,

1989
Differential diagnosis of childhood asthma.
    Current problems in pediatrics, 1974, Volume: 4, Issue:5

    Topics: Age Factors; Asthma; Child; Child Health Services; Child, Institutionalized; Cystic Fibrosis; Defici

1974

Trials

7 trials available for theophylline and Cystic Fibrosis

ArticleYear
Radionuclide assessment of cardiac performance in cystic fibrosis. Reproducibility and effect of theophylline on cardiac function.
    The American review of respiratory disease, 1984, Volume: 130, Issue:5

    Topics: Adolescent; Adult; Aminophylline; Cardiac Output; Cystic Fibrosis; Erythrocytes; Female; Heart; Huma

1984
Reliable diagnosis of the major type of cystic fibrosis with fibroblast cultures. A double blind study.
    Acta paediatrica Scandinavica, 1978, Volume: 67, Issue:5

    Topics: Adolescent; Adult; Alkaline Phosphatase; Cells, Cultured; Child; Child, Preschool; Clinical Trials a

1978
The paradoxical effect of adrenergic and methylxanthine drugs in cystic fibrosis.
    Pediatrics, 1976, Volume: 58, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aerosols; Child; Clinical Trials as Topic; Cystic Fibrosis;

1976
Effect of theophylline on lung function tests, sleep quality, and nighttime SaO2 in children with cystic fibrosis.
    The American review of respiratory disease, 1991, Volume: 144, Issue:6

    Topics: Child; Cystic Fibrosis; Double-Blind Method; Female; Heart Rate; Humans; Male; Monitoring, Physiolog

1991
Bronchodilation from intravenous theophylline in patients with cystic fibrosis: results of a blinded placebo-controlled crossover clinical trial.
    Pediatric pulmonology, 1989, Volume: 6, Issue:3

    Topics: Adolescent; Adult; Bronchi; Child; Clinical Trials as Topic; Cystic Fibrosis; Double-Blind Method; F

1989
Clinical efficacy of ciprofloxacin in lower respiratory tract infections.
    Scandinavian journal of infectious diseases. Supplementum, 1989, Volume: 60

    Topics: Ciprofloxacin; Clinical Trials as Topic; Cystic Fibrosis; Drug Interactions; Humans; Lung Diseases,

1989
Cystic fibrosis: enhanced theophylline metabolism may be linked to the disease.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:3

    Topics: Adolescent; Adult; Biotransformation; Chromatography, High Pressure Liquid; Clinical Trials as Topic

1988

Other Studies

28 other studies available for theophylline and Cystic Fibrosis

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regu

2016
Review of the British Thoracic Society Winter Meeting 2018, 5-7 December 2018, London, UK.
    Thorax, 2019, Volume: 74, Issue:12

    Topics: Asthma; Bronchodilator Agents; Cystic Fibrosis; Drug Resistance, Microbial; Genetic Therapy; Humans;

2019
Factors influencing adenovirus-mediated airway transduction in fetal mice.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2005, Volume: 12, Issue:3

    Topics: Adenosine; Adenoviridae; Animals; Carbon; Carbon Dioxide; Colloids; Cystic Fibrosis; Enzyme-Linked I

2005
Defective beta adrenergic response of cystic fibrosis sweat glands in vivo and in vitro.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:6

    Topics: Atropine; Child; Cystic Fibrosis; Humans; Isoproterenol; Methacholine Chloride; Methacholine Compoun

1984
Pharmacokinetics of theophylline and bioavailability of a sustained release theophylline preparation in patients with cystic fibrosis.
    Annals of allergy, 1983, Volume: 50, Issue:3

    Topics: Adolescent; Adult; Biological Availability; Child; Cystic Fibrosis; Delayed-Action Preparations; Die

1983
Theophylline disposition in cystic fibrosis.
    The American review of respiratory disease, 1983, Volume: 127, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Cystic Fibrosis; Dose-Response Relationship, Drug; Female;

1983
[Obstructive airway diseases in children].
    Wiener medizinische Wochenschrift (1946), 1982, Feb-28, Volume: 132, Issue:4

    Topics: Abscess; Adult; Asthma; Child; Child, Preschool; Cystic Fibrosis; Foreign-Body Reaction; Humans; Inh

1982
Oral theophylline disposition in cystic fibrosis.
    Annals of allergy, 1982, Volume: 48, Issue:3

    Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Cystic Fibrosis; Female; Half-Life; Human

1982
Alkaline phosphatase activity of normal and cystic fibrosis fibroblasts.
    Journal of medical genetics, 1980, Volume: 17, Issue:3

    Topics: Alkaline Phosphatase; Cells, Cultured; Child; Cystic Fibrosis; Female; Glycoproteins; Humans; Isopro

1980
Possible regulation of CFTR-chloride channels by membrane-bound phosphatases in pancreatic duct cells.
    FEBS letters, 1993, Aug-02, Volume: 327, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Alkaline Phosphatase; Base Sequence; Chloride Channels; Chlorides; Cyst

1993
Increased physiological dead space during exercise after bronchodilation in cystic fibrosis.
    Pediatric pulmonology, 1993, Volume: 15, Issue:5

    Topics: Adolescent; Airway Resistance; Albuterol; Bronchi; Cystic Fibrosis; Female; Humans; Male; Physical E

1993
In vivo measurement of chloride and water secretion in the jejunum of cystic fibrosis patients.
    Pediatric research, 1996, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Bicarbonates; Body Water; Catheterization; Chlorides; Cystic Fibrosis; Electrophy

1996
The CFTR-mediated protein secretion defect: pharmacological correction.
    Pflugers Archiv : European journal of physiology, 2001, Volume: 443 Suppl 1

    Topics: Adrenergic beta-Agonists; Animals; Cell Line; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmemb

2001
Reliable detection of cystic fibrosis in skin-derived fibroblast cultures.
    Human genetics, 1978, Mar-17, Volume: 41, Issue:2

    Topics: Alkaline Phosphatase; Cells, Cultured; Cystic Fibrosis; Enzyme Induction; Female; Fibroblasts; Glyco

1978
Variability of the serum protein binding of theophylline in patients with asthma and cystic fibrosis.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Aged; Asthma; Blood Proteins; Chromatography, High Pressure Liquid; Cystic Fibros

1992
Relationship between serum and saliva theophylline levels in patients with cystic fibrosis.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Asthma; Child; Cystic Fibrosis; Humans; Lung Diseases; Regression Analysis; Saliv

1992
A potential animal model for studying CF heterozygote advantage: genetic variation in theophylline-inducible colonic chloride currents among inbred strains of mice.
    Biochemical medicine and metabolic biology, 1992, Volume: 47, Issue:1

    Topics: Animals; Chlorides; Colon; Cystic Fibrosis; Disease Models, Animal; Electric Conductivity; Female; G

1992
Cystic fibrosis and seizures.
    Lancet (London, England), 1991, Jul-27, Volume: 338, Issue:8761

    Topics: Adult; Ciprofloxacin; Cystic Fibrosis; Humans; Seizures; Theophylline

1991
In vivo evidence of altered chloride but not potassium secretion in cystic fibrosis rectal mucosa.
    Gastroenterology, 1991, Volume: 101, Issue:4

    Topics: Adult; Bethanechol; Bethanechol Compounds; Biological Transport, Active; Calcium; Chlorides; Cyclic

1991
Expression of normal and cystic fibrosis phenotypes by continuous airway epithelial cell lines.
    The American journal of physiology, 1990, Volume: 259, Issue:6 Pt 1

    Topics: Antigens, Polyomavirus Transforming; Base Sequence; Biomarkers; Blood Proteins; Bradykinin; Calcimyc

1990
Variable theophylline clearance in cystic fibrosis.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:2

    Topics: Adult; Ciprofloxacin; Cystic Fibrosis; Drug Interactions; Humans; Male; Metabolic Clearance Rate; Th

1991
cAMP dependent chloride conductance is not different in cystic fibrosis fibroblasts.
    Life sciences, 1990, Volume: 46, Issue:18

    Topics: Alprostadil; Biological Transport, Active; Bucladesine; Cell Line; Chlorides; Cyclic AMP; Cystic Fib

1990
Effect of cyclic adenosine monophosphate elevations on functional responses of polymorphonuclear leukocytes from patients with cystic fibrosis.
    Pediatric pulmonology, 1989, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Child; Child, Preschool; Colforsin; Cyclic AMP; Cystic Fibrosis; Cytoplasmic Gran

1989
Altered intestinal chloride transport in cystic fibrosis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1988, Volume: 2, Issue:10

    Topics: Adult; Amiloride; Biological Transport; Calcimycin; Chlorides; Cyclic AMP; Cystic Fibrosis; Electric

1988
[Respiratory insufficiency in mucoviscidosis. Pathophysiologic aspects of conservative drug therapy].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1989, Volume: 137, Issue:1

    Topics: Acid-Base Equilibrium; Child; Combined Modality Therapy; Cystic Fibrosis; Drug Therapy, Combination;

1989
Rectum has abnormal ion transport but normal cAMP-binding proteins in cystic fibrosis.
    The American journal of physiology, 1988, Volume: 254, Issue:5 Pt 1

    Topics: Adult; Amiloride; Biological Transport, Active; Carrier Proteins; Chlorides; Cyclic AMP Receptor Pro

1988
Airway obstruction and airway wall instability in cystic fibrosis: the isolated and combined effect of theophylline and sympathomimetics.
    Pediatric pulmonology, 1988, Volume: 4, Issue:4

    Topics: Adolescent; Adult; Airway Obstruction; Albuterol; Child; Cystic Fibrosis; Drug Therapy, Combination;

1988
Salivary gland enlargement and functional changes during feeding of pancreatin to rats. (Possible relation to functional changes in cystic fibrosis).
    Pediatric research, 1969, Volume: 3, Issue:6

    Topics: Animals; Cyclic AMP; Cystic Fibrosis; Male; Organ Size; Pancreatin; Parotid Gland; Rats; Saliva; Sal

1969