theophylline has been researched along with Cough in 27 studies
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the safety and efficacy of Linkus, Aminophylline with Diphenhydramine group and Acefyllin Piperazine with Diphenhydramine cough syrup on children having cough and sleep difficulty associated with cough." | 9.22 | Efficacy and safety of Linkus, Aminophylline diphenhydramine and acefyllin piperazine for the treatment of cough in children. ( Naveed, S; Rehman, H; Usmanghani, K, 2016) |
| "We sought to investigate the inhibitory activity of theophylline on vagal sensory nerve activity and the cough reflex." | 7.80 | Theophylline inhibits the cough reflex through a novel mechanism of action. ( Adcock, JJ; Belvisi, MG; Birrell, MA; Dubuis, E; Grace, MS; Maher, SA; Wortley, MA, 2014) |
| "A total of 58 patients with asthma having chronic cough refractory to ICS/LABA were randomized in a 2:1 ratio to add tiotropium 5 μg (39 patients) or theophylline 400 mg (19 patients) for 4 weeks." | 5.69 | Tiotropium for refractory cough in asthma via cough reflex sensitivity: A randomized, parallel, open-label trial. ( Fukuda, S; Fukumitsu, K; Inoue, Y; Ito, K; Ito, Y; Kanemitsu, Y; Kurokawa, R; Maeno, K; Mori, Y; Niimi, A; Nishiyama, H; Oguri, T; Ohkubo, H; Tajiri, T; Takeda, N; Takemura, M; Uemura, T; Yamamoto, S, 2023) |
| "To evaluate the safety and efficacy of Linkus, Aminophylline with Diphenhydramine group and Acefyllin Piperazine with Diphenhydramine cough syrup on children having cough and sleep difficulty associated with cough." | 5.22 | Efficacy and safety of Linkus, Aminophylline diphenhydramine and acefyllin piperazine for the treatment of cough in children. ( Naveed, S; Rehman, H; Usmanghani, K, 2016) |
| "Sixty patients with cough due to BHR (shown by positive bronchial provocation test) were randomly divided into Chinese medicine group (n = 30) and control group (n = 30) to receive Bufeishenqingre decoction twice a day and 100 mg theophylline sustained-release capsules twice a day for one month, respectively." | 5.14 | [Effect of Bufeishenqingre decoction on bronchial hyperresponsiveness-induced cough]. ( Dou, YQ; Liu, Y; Yang, MH; Zhang, Y, 2010) |
| " The benefits of methylxanthine-based therapies in the apnea of prematurity and their translational potential in pediatric affections of the respiratory tract are here presented." | 4.93 | The potential of methylxanthine-based therapies in pediatric respiratory tract diseases. ( Franco, R; Martínez-Pinilla, E; Oñatibia-Astibia, A, 2016) |
| "Capsaicin, a TRPV1 agonist, stimulates both the cough and swallowing reflexes." | 4.93 | Chemical Senses Affecting Cough and Swallowing. ( Ebihara, S; Ebihara, T; Izukura, H; Miyagi, M; Okuni, I; Sekiya, H, 2016) |
| "We sought to investigate the inhibitory activity of theophylline on vagal sensory nerve activity and the cough reflex." | 3.80 | Theophylline inhibits the cough reflex through a novel mechanism of action. ( Adcock, JJ; Belvisi, MG; Birrell, MA; Dubuis, E; Grace, MS; Maher, SA; Wortley, MA, 2014) |
| "In this study the effects of non-selective PDE inhibitors (theophylline and theobromine) and selective inhibitors of PDE 1, 3, 4 and 5 on cough, induced by citric acid, were evaluated." | 3.77 | The influence of the PDE inhibitors on cough reflex in guinea pigs. ( Mokry, J; Nosalova, G, 2011) |
| "In the present study, we evaluated the effect of roxithromycin, a semisynthetic macrolide antibiotic, on the cough response to inhaled acetic acid (AA) and on the bronchoconstriction induced by ultrasonically nebulized distilled water (UNDW) in children with asthma." | 3.69 | Roxithromycin attenuates acid-induced cough and water-induced bronchoconstriction in children with asthma. ( Kato, M; Maeda, S; Mochizuki, H; Morikawa, A; Shimizu, T; Takei, K; Tokuyama, K, 1997) |
| " The added observation that theophylline and salbutamol were effective suggests that the condition is a manifestation of asthma." | 3.66 | Persistent cough a forme-fruste of asthma. ( Benzaray, S; Katznelson, D; Yahav, Y, 1982) |
| "Drug therapy of asthma in the elderly with sympathomimetics, theophylline, steroids, and mucokinetic agents is described, with discussion of dosage evaluation, toxicity, possible drug interactions, and suggested management of common problems." | 3.66 | Management of respiratory problems in the aged. ( Ziment, I, 1982) |
| "Treatment of COPD patients with TP is more effective than with theophylline." | 2.73 | Clinical efficacy of the transdermal tulobuterol patch in patients with chronic obstructive pulmonary disease: a comparison with slow-release theophylline. ( Aizawa, H; Gohara, R; Ichiki, M; Iwanaga, T; Kawayama, T; Kinoshita, M; Koga, H; Minami, S; Nishiyama, M; Sueyasu, Y, 2008) |
| " It has been discovered that theophylline, when dosed 10 mg per kg of body weight i." | 1.29 | [The antitussive effect of theophylline]. ( Nemceková, E; Nosál'ová, G; Rybár, A, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (51.85) | 18.7374 |
| 1990's | 4 (14.81) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 7 (25.93) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Fukumitsu, K | 1 |
| Kanemitsu, Y | 1 |
| Kurokawa, R | 1 |
| Takeda, N | 1 |
| Tajiri, T | 1 |
| Nishiyama, H | 1 |
| Ito, K | 1 |
| Inoue, Y | 1 |
| Yamamoto, S | 1 |
| Mori, Y | 1 |
| Fukuda, S | 1 |
| Uemura, T | 1 |
| Ohkubo, H | 1 |
| Maeno, K | 1 |
| Ito, Y | 1 |
| Oguri, T | 1 |
| Takemura, M | 1 |
| Niimi, A | 1 |
| Dubuis, E | 1 |
| Wortley, MA | 1 |
| Grace, MS | 1 |
| Maher, SA | 1 |
| Adcock, JJ | 1 |
| Birrell, MA | 1 |
| Belvisi, MG | 1 |
| Oñatibia-Astibia, A | 1 |
| Martínez-Pinilla, E | 1 |
| Franco, R | 1 |
| Ebihara, S | 1 |
| Izukura, H | 1 |
| Miyagi, M | 1 |
| Okuni, I | 1 |
| Sekiya, H | 1 |
| Ebihara, T | 1 |
| Rehman, H | 1 |
| Naveed, S | 1 |
| Usmanghani, K | 1 |
| Yakoot, M | 1 |
| Salem, A | 1 |
| Omar, AM | 1 |
| Zhang, Y | 1 |
| Yang, MH | 1 |
| Dou, YQ | 1 |
| Liu, Y | 1 |
| Mokry, J | 1 |
| Nosalova, G | 1 |
| TOWNLEY, RG | 1 |
| BRONSTEIN, SB | 1 |
| BREATHNACH, CS | 1 |
| Minami, S | 1 |
| Kawayama, T | 1 |
| Ichiki, M | 1 |
| Nishiyama, M | 1 |
| Sueyasu, Y | 1 |
| Gohara, R | 1 |
| Kinoshita, M | 1 |
| Koga, H | 1 |
| Iwanaga, T | 1 |
| Aizawa, H | 1 |
| Nagy, G | 1 |
| Yahav, Y | 1 |
| Katznelson, D | 1 |
| Benzaray, S | 1 |
| Ziment, I | 1 |
| Cloutier, MM | 1 |
| Loughlin, GM | 1 |
| Nemceková, E | 1 |
| Nosál'ová, G | 1 |
| Rybár, A | 1 |
| Cazzola, M | 1 |
| Matera, MG | 1 |
| Liccardi, G | 1 |
| De Prisco, F | 1 |
| D'Amato, G | 1 |
| Rossi, F | 1 |
| Shimizu, T | 1 |
| Kato, M | 1 |
| Mochizuki, H | 1 |
| Takei, K | 1 |
| Maeda, S | 1 |
| Tokuyama, K | 1 |
| Morikawa, A | 1 |
| Forsberg, K | 1 |
| Karlsson, JA | 1 |
| Zackrisson, C | 1 |
| Persson, CG | 1 |
| Pomari, C | 1 |
| Turco, P | 1 |
| Dal Negro, R | 1 |
| Manresa, F | 1 |
| Clay, TP | 1 |
| Thompson, MA | 1 |
| Renovanz, HD | 2 |
| Etter, RL | 1 |
| Jackson, RH | 1 |
| Raymer, WJ | 1 |
| Qaqundah, BY | 1 |
| Taylor, WF | 1 |
| Baker, TR | 1 |
| Oscherwitz, M | 1 |
| Corlin, R | 1 |
| Jarboe, T | 1 |
| Teisch, J | 1 |
| Nichaman, MZ | 1 |
3 reviews available for theophylline and Cough
| Article | Year |
|---|---|
The potential of methylxanthine-based therapies in pediatric respiratory tract diseases.
Topics: Adolescent; Apnea; Asthma; Bronchodilator Agents; Caffeine; Child; Child, Preschool; Cough; Humans; | 2016 |
Chemical Senses Affecting Cough and Swallowing.
Topics: Acids; Angiotensin-Converting Enzyme Inhibitors; Animals; Capsaicin; Cigarette Smoking; Cough; Deglu | 2016 |
Theory and practice of the use of expectorants reviewed from clinical aspects.
Topics: Acetylcysteine; Bromhexine; Carbocysteine; Cilia; Cough; Expectorants; Guaiacol; Humans; Mucus; Poly | 1984 |
9 trials available for theophylline and Cough
| Article | Year |
|---|---|
Tiotropium for refractory cough in asthma via cough reflex sensitivity: A randomized, parallel, open-label trial.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Asthma; Ca | 2023 |
Efficacy and safety of Linkus, Aminophylline diphenhydramine and acefyllin piperazine for the treatment of cough in children.
Topics: Age Factors; Aminophylline; Antitussive Agents; Bronchodilator Agents; Child; Child, Preschool; Coug | 2016 |
Clinical efficacy of farcosolvin syrup (ambroxol-theophylline-guaiphenesin mixture) in the treatment of acute exacerbation of chronic bronchitis.
Topics: Aged; Ambroxol; Bronchitis, Chronic; Bronchodilator Agents; Cough; Drug Combinations; Egypt; Expecto | 2010 |
[Effect of Bufeishenqingre decoction on bronchial hyperresponsiveness-induced cough].
Topics: Adult; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchodilator Agents; Cough; Drugs, | 2010 |
Clinical efficacy of the transdermal tulobuterol patch in patients with chronic obstructive pulmonary disease: a comparison with slow-release theophylline.
Topics: Activities of Daily Living; Administration, Cutaneous; Aged; Aged, 80 and over; Bronchodilator Agent | 2008 |
Theophylline in the inhibition of angiotensin-converting enzyme inhibitor-induced cough.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Cough; Double-Blind Method; Female; Humans; M | 1993 |
[Clinical pharmacology in the domain of pulmonology].
Topics: Acetylcholine; Adrenal Cortex Hormones; Aerosols; Antitussive Agents; Asthma; Bronchodilator Agents; | 1970 |
[Clinical pharmacology in the domain of pulmonology].
Topics: Acetylcholine; Adrenal Cortex Hormones; Aerosols; Antitussive Agents; Asthma; Bronchodilator Agents; | 1970 |
Effects of theophylline-alcohol with potassium iodide in asthmatic patients.
Topics: Adult; Asthma; Clinical Trials as Topic; Cough; Dyspnea; Female; Humans; Male; Potassium Iodide; Res | 1969 |
15 other studies available for theophylline and Cough
| Article | Year |
|---|---|
Theophylline inhibits the cough reflex through a novel mechanism of action.
Topics: Action Potentials; Animals; Antitussive Agents; Calcium; Capsaicin; Cough; Disease Models, Animal; G | 2014 |
The influence of the PDE inhibitors on cough reflex in guinea pigs.
Topics: Animals; Antitussive Agents; Bronchial Hyperreactivity; Citric Acid; Cough; Guinea Pigs; Male; Ovalb | 2011 |
A DOUBLE BLIND CLINICAL EVALUATION OF GLYCERYL GUAIACOLATE.
Topics: Asthma; Bronchiectasis; Bronchitis; Choline; Cough; Double-Blind Method; Guaifenesin; Pulmonary Emph | 1963 |
COUGH SYNCOPE--THE MECHANISM IN TWO CASES.
Topics: Cough; Humans; Syncope; Theophylline; Toxicology | 1964 |
Persistent cough a forme-fruste of asthma.
Topics: Adolescent; Aerosols; Albuterol; Asthma; Bronchial Spasm; Child; Child, Preschool; Cough; Eosinophil | 1982 |
Management of respiratory problems in the aged.
Topics: Aged; Asthma; Common Cold; Cough; Expectorants; Glucocorticoids; Humans; Lung Diseases, Obstructive; | 1982 |
Chronic cough in children: a manifestation of airway hyperreactivity.
Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Child; Chronic Disease; Cough; Female; Humans; Isoprot | 1981 |
[The antitussive effect of theophylline].
Topics: Animals; Cats; Cough; Reflex; Theophylline | 1994 |
Roxithromycin attenuates acid-induced cough and water-induced bronchoconstriction in children with asthma.
Topics: Acetic Acid; Adolescent; Anti-Bacterial Agents; Asthma; Bronchoconstriction; Child; Cough; Female; F | 1997 |
Selective inhibition of cough and bronchoconstriction in conscious guinea pigs.
Topics: Animals; Antitussive Agents; Bronchoconstriction; Bronchodilator Agents; Citrates; Citric Acid; Coug | 1992 |
Has theophylline a role in the cure and prevention of ACE-inhibitor-related cough?
Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Cough; Female; Humans; Middle Aged; Theophyllin | 1989 |
Should symptoms--namely cough and dyspnoea--be treated?
Topics: Codeine; Cough; Diazepam; Dyspnea; Ethanol; Humans; Oxygen Inhalation Therapy; Promethazine; Theophy | 1986 |
Irritant induced cough as a model of intrapulmonary airway reactivity.
Topics: Airway Resistance; Animals; Bronchial Provocation Tests; Citrates; Citric Acid; Cough; Guinea Pigs; | 1985 |
Recurrent right middle lobe syndrome in an asthmatic child. Case report and serial vectorcardiographic study.
Topics: Asthma; Child; Cough; Ephedrine; Female; Humans; Middle Lobe Syndrome; Pain; Phenobarbital; Predniso | 1970 |
Screening and treatment program for mild chronic obstructive pulmonary disease.
Topics: Adult; Aerosols; Bronchodilator Agents; Chronic Disease; Cough; Ephedrine; Epinephrine; Follow-Up St | 1970 |