Page last updated: 2024-10-22

theophylline and Cirrhoses, Experimental Liver

theophylline has been researched along with Cirrhoses, Experimental Liver in 6 studies

Research Excerpts

ExcerptRelevanceReference
"To explore a possible role for adenosine in the pathogenesis of the splanchnic hyperemia of cirrhosis, we administered 8-phenyltheophylline, a specific adenosine receptor antagonist, to rats with biliary cirrhosis caused by bile duct ligation and to control sham-operated rats."7.68Adenosine receptor blockade reduces splanchnic hyperemia in cirrhotic rats. ( Chilton, EL; Lee, SS; Pak, JM, 1992)
"To explore a possible role for adenosine in the pathogenesis of the splanchnic hyperemia of cirrhosis, we administered 8-phenyltheophylline, a specific adenosine receptor antagonist, to rats with biliary cirrhosis caused by bile duct ligation and to control sham-operated rats."3.68Adenosine receptor blockade reduces splanchnic hyperemia in cirrhotic rats. ( Chilton, EL; Lee, SS; Pak, JM, 1992)
" Using a bivascular liver perfusion dose-response curves to adenosine of the HA were performed in the presence and the absence of pan-adenosine blocker (8-SPT), A1 blocker (caffeine) or nitric oxide synthase-blocker (l-NMMA) after preconstriction with an alpha1-agonist (methoxamine)."1.36A distinct nitric oxide and adenosine A1 receptor dependent hepatic artery vasodilatatory response in the CCl-cirrhotic liver. ( Groszmann, RJ; Mehal, WZ; Ripoll, C; Zipprich, A, 2010)
"This experiment was performed to evaluate the usefulness of an experimental fibrosis model by bile duct ligation as a pharmacokinetic model of a disease state."1.29Pharmacokinetics of theophylline: effects of hepatic fibrosis in rats induced bile duct ligation. ( Ham, SH; Han, SS; Kim, JB; Kim, KY; Sohn, DH, 1995)
"Theophylline (3 mg/kg) was administered intravenously on two separate occasions, 24 hours apart, during which time the rats breathed either room air or oxygen (95%) from 1 hour before dosing until the end of plasma sampling with a randomized order of gas exposure."1.29Oxygen supplementation restores theophylline clearance to normal in cirrhotic rats. ( Angus, PW; Hickey, PL; McLean, AJ; Morgan, DJ, 1995)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zipprich, A1
Mehal, WZ1
Ripoll, C1
Groszmann, RJ1
Han, SS1
Kim, KY1
Ham, SH1
Sohn, DH2
Kim, JB1
Hickey, PL1
Angus, PW1
McLean, AJ1
Morgan, DJ1
Park, EJ1
Ko, G1
Kim, J1
Lee, SS1
Chilton, EL1
Pak, JM1
Arimori, K1
Wakayama, K1
Nakano, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Implementing a Nurse Caring Behavior Protocol on Postoperative Cardiac Patient Satisfaction: A Randomized Controlled Trial[NCT05446844]60 participants (Actual)Interventional2019-10-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for theophylline and Cirrhoses, Experimental Liver

ArticleYear
A distinct nitric oxide and adenosine A1 receptor dependent hepatic artery vasodilatatory response in the CCl-cirrhotic liver.
    Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:7

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Blotting, Western; Caffeine; Carbon Tetrachlo

2010
Pharmacokinetics of theophylline: effects of hepatic fibrosis in rats induced bile duct ligation.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile Ducts; Biliru

1995
Oxygen supplementation restores theophylline clearance to normal in cirrhotic rats.
    Gastroenterology, 1995, Volume: 108, Issue:5

    Topics: Administration, Inhalation; Animals; Carbon Tetrachloride; Chromatography, High Pressure Liquid; Liv

1995
Biotransformation of theophylline in cirrhotic rats induced by biliary obstruction.
    Archives of pharmacal research, 1999, Volume: 22, Issue:1

    Topics: Animals; Area Under Curve; Biotransformation; Body Weight; Bronchodilator Agents; Cholestasis; Half-

1999
Adenosine receptor blockade reduces splanchnic hyperemia in cirrhotic rats.
    Hepatology (Baltimore, Md.), 1992, Volume: 15, Issue:6

    Topics: Adenosine; Animals; Hemodynamics; Hyperemia; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental

1992
Increased transport of theophylline into gastrointestinal lumen and gastrointestinal dialysis by activated charcoal in rats with hepatic cirrhosis.
    Chemical & pharmaceutical bulletin, 1989, Volume: 37, Issue:11

    Topics: Animals; Charcoal; Dialysis; Intestinal Absorption; Liver Cirrhosis, Experimental; Male; Rats; Rats,

1989