theophylline has been researched along with Carcinoma, Hepatocellular in 27 studies
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was undertaken to assess the adenosine receptor regulation of erythropoietin (Ep) secretion in hepatocellular carcinoma cells (Hep3B) in response to hypoxia." | 3.68 | [Increase in erythropoietin secretion mediated by adenosine A2 receptors]. ( Fisher, JW; Nakashima, J; Tazaki, H, 1993) |
| " On the other hand, 8-phenyltheophylline, an adenosine receptor antagonist, significantly inhibited the stimulatory effects of CHA on both Ep secretion and cAMP accumulation in the Hep 3B cell cultures in response to hypoxia." | 3.68 | Increased erythropoietin secretion in human hepatoma cells by N6-cyclohexyladenosine. ( Beckman, B; Brookins, J; Fisher, JW; Nakashima, J, 1991) |
| " A dose-response curve for insulin synthesis was also generated to increasing concentrations of glucose with a half Vmax of 4." | 1.29 | Functional expression of the human insulin gene in a human hepatoma cell line (HEP G2). ( Marshall, GM; Simpson, AM; Swan, MA; Tu, J; Tuch, BE, 1995) |
| "Human HEP G2 hepatoma cells respond to cAMP or insulin with stimulation or inhibition of IGFBP-1 expression, respectively; however, dexamethasone alone does not stimulate IGFBP-1 expression." | 1.29 | Dexamethasone stimulates expression of insulin-like growth factor binding protein-1 in HEP G2 human hepatoma cells. ( DePaolis, LA; Lee, PD; Morris, SL; Powell, D; Suwanichkul, A, 1993) |
| "In vitro cultures of an Epo producing hepatocellular carcinoma (Hep3B) cell line with NECA (> or = 10(-6) M) for 20 hours under hypoxic conditions (1% O2) produced significant increases in medium levels of Epo when compared with hypoxia controls." | 1.29 | Effects of 5'-N-ethylcarboxamideadenosine (NECA) on erythropoietin production. ( Agrawal, KC; Beckman, BS; Brookins, JW; Fisher, JW; Nakashima, J; Ohigashi, T, 1993) |
| "A 24h pretreatment of the human hepatoma cell line HepG2 with dibutyryl cyclic AMP in the presence of theophylline induced a dose dependent decrease in low density lipoprotein binding, uptake and degradation." | 1.27 | Cyclic AMP decreases LDL catabolism and cholesterol synthesis in the human hepatoma cell line HepG2. ( Auclair, M; Maziere, C; Maziere, JC; Mora, L; Moreau, M; Polonovski, J; Salmon, S, 1988) |
| "In a different type of hepatoma cell which is less malignant and forms a small tissue mass or island, cell surface ATPase activity at cell-cell contacts in an island is very weak or scarcely detected even when cells are not treated with dibutyryl cyclic AMP and theophylline." | 1.26 | Surface ATPase activity at cell-cell contacts in hepatic parenchymal cells and in cAMP-treated hepatoma cells in monolayer culture. ( Ohnishi, T; Yamaguchi, K, 1977) |
| "AH-66 rat ascites hepatoma cells incorporated [14C]leucine into the AFP fraction." | 1.25 | Synthesis of alpha-fetoprotein by rat ascites hepatoma cells. ( Endo, Y; Kanai, K; Kaneko, Y; Oda, T, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (66.67) | 18.7374 |
| 1990's | 7 (25.93) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gressner, OA | 1 |
| Wu, LF | 1 |
| Li, GP | 1 |
| Feng, JL | 1 |
| Pu, ZJ | 1 |
| Simpson, AM | 1 |
| Tuch, BE | 1 |
| Swan, MA | 1 |
| Tu, J | 1 |
| Marshall, GM | 1 |
| Powell, D | 1 |
| Lee, PD | 2 |
| DePaolis, LA | 2 |
| Morris, SL | 1 |
| Suwanichkul, A | 2 |
| Powell, DR | 1 |
| Nakashima, J | 3 |
| Ohigashi, T | 1 |
| Brookins, JW | 1 |
| Beckman, BS | 1 |
| Agrawal, KC | 1 |
| Fisher, JW | 3 |
| Tazaki, H | 1 |
| Gopalakrishnan, TV | 1 |
| Thompson, EB | 1 |
| Kanai, K | 1 |
| Endo, Y | 1 |
| Oda, T | 1 |
| Kaneko, Y | 1 |
| Isaka, H | 1 |
| Umehara, S | 1 |
| Tsukada, Y | 1 |
| Hickie, RA | 1 |
| Walker, CM | 1 |
| Datta, A | 1 |
| Gunn, JM | 2 |
| Tilghman, SM | 1 |
| Hanson, RW | 2 |
| Reshef, L | 2 |
| Ballard, FJ | 2 |
| Knowles, SE | 1 |
| Castagna, M | 1 |
| Boy, J | 1 |
| Chauveau, J | 1 |
| Flodrops, M | 1 |
| Yamaguchi, K | 1 |
| Ohnishi, T | 1 |
| Wagner, K | 1 |
| Roper, MD | 1 |
| Leichtling, BH | 1 |
| Wimalasena, J | 1 |
| Wicks, WD | 1 |
| Brookins, J | 1 |
| Beckman, B | 1 |
| Ganapathi, MK | 1 |
| Mackiewicz, A | 1 |
| Samols, D | 1 |
| Brabenec, A | 1 |
| Kushner, I | 1 |
| Schultz, D | 1 |
| Hu, SI | 1 |
| Maziere, C | 1 |
| Maziere, JC | 1 |
| Salmon, S | 1 |
| Auclair, M | 1 |
| Mora, L | 1 |
| Moreau, M | 1 |
| Polonovski, J | 1 |
| Schröder, J | 1 |
| Plagemann, PG | 2 |
| Manganiello, V | 1 |
| Vaughan, M | 1 |
| Sheppard, JR | 1 |
| Granner, D | 1 |
| Chase, LR | 1 |
| Aurbach, GD | 1 |
| Tomkins, GM | 1 |
| Reynolds, RD | 2 |
| Scott, DF | 3 |
| Potter, VR | 3 |
| Morris, HP | 3 |
| Butcher, FR | 1 |
| Watanabe, M | 1 |
1 review available for theophylline and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Less Smad2 is good for you! A scientific update on coffee's liver benefits.
Topics: Acetylgalactosamine; Animals; Caffeine; Carcinoma, Hepatocellular; Collagen Type I; Connective Tissu | 2009 |
26 other studies available for theophylline and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Molecular mechanisms of adenosine-induced apoptosis in human HepG2 cells.
Topics: Adenosine; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Line, Tumor; Cell Prolife | 2006 |
Functional expression of the human insulin gene in a human hepatoma cell line (HEP G2).
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; DNA, Com | 1995 |
Dexamethasone stimulates expression of insulin-like growth factor binding protein-1 in HEP G2 human hepatoma cells.
Topics: Animals; Blotting, Northern; Carcinoma, Hepatocellular; Carrier Proteins; Cyclic AMP; Dexamethasone; | 1993 |
Identification of a promoter element which participates in cAMP-stimulated expression of human insulin-like growth factor-binding protein-1.
Topics: Base Sequence; Bucladesine; Carcinoma, Hepatocellular; Carrier Proteins; Cell Nucleus; Chloramphenic | 1993 |
Effects of 5'-N-ethylcarboxamideadenosine (NECA) on erythropoietin production.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carci | 1993 |
[Increase in erythropoietin secretion mediated by adenosine A2 receptors].
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Carcinoma, Hep | 1993 |
Effect of concanavalin A on tyrosine aminotransferase in rat hepatoma tissue culture cells. Rapid reversible inactivation of soluble enzyme.
Topics: Alanine Transaminase; Animals; Carcinoma, Hepatocellular; Cell Line; Concanavalin A; Cyclic AMP; Cyc | 1977 |
Synthesis of alpha-fetoprotein by rat ascites hepatoma cells.
Topics: alpha-Fetoproteins; Animals; Bucladesine; Carcinoma, Hepatocellular; Fetal Proteins; Kinetics; Leuci | 1975 |
Alpha-Fetoprotein synthesis in cultured cells: studies on Yoshida sarcoma and ascites hepatoma in vitro.
Topics: Adenosine Monophosphate; alpha-Fetoproteins; Animals; Bucladesine; Butyrates; Carcinoma, Hepatocellu | 1975 |
Increased activity of low-Km cyclic adenosine 3':5'-monophosphate phosphodiesterase in plasma membranes of Morris hepatoma 5123tc (h).
Topics: Animals; Carcinoma, Hepatocellular; Cell Fractionation; Cell Membrane; Cyclic AMP; Depression, Chemi | 1975 |
Effects of cyclic adenosine monophosphate, dexamethasone and insulin on phosphoenolpyruvate carboxykinase synthesis in Reuber H-35 hepatoma cells.
Topics: Animals; Bucladesine; Carcinoma, Hepatocellular; Cells, Cultured; Dactinomycin; Deoxyadenosines; Dex | 1975 |
Properties of phosphoenolpyruvate carboxykinase (guanosine triphosphate) synthesized in hepatoma cells in the presence of amino acid analogues.
Topics: Amino Acids; Antibodies; Bucladesine; Canavanine; Carcinoma, Hepatocellular; Cell Line; Dexamethason | 1975 |
[Effects of theophylline on chemically induced liver tumorogenesis and on bladder membranes in rats].
Topics: Animals; Carcinoma, Hepatocellular; Depression, Chemical; Feeding Behavior; Liver Neoplasms; p-Dimet | 1975 |
Surface ATPase activity at cell-cell contacts in hepatic parenchymal cells and in cAMP-treated hepatoma cells in monolayer culture.
Topics: Adenosine Triphosphatases; Bucladesine; Carcinoma, Hepatocellular; Cell Division; Cell Membrane; Cel | 1977 |
Effects of 6- and 8-substituted analogs of adenosine 3':5'-monophosphate on phosphoenolpyruvate carboxykinase and tyrosine aminotransferase in hepatoma cell cultures.
Topics: Animals; Butyrates; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Cyclic AMP; Cyclic G | 1975 |
Increased erythropoietin secretion in human hepatoma cells by N6-cyclohexyladenosine.
Topics: Adenosine; Anaerobiosis; Bucladesine; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Cyclic AM | 1991 |
Induction of C-reactive protein by cytokines in human hepatoma cell lines is potentiated by caffeine.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; C-Reactive Protein; Caffeine; Calcimycin; Calcium; Carcinoma | 1990 |
Cyclic AMP decreases LDL catabolism and cholesterol synthesis in the human hepatoma cell line HepG2.
Topics: Acetates; Acetic Acid; Bucladesine; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Cyclic AMP; H | 1988 |
Cyclic 3',5'-nucleotide phosphodiesterases of Novikoff rat hepatoma, mouse L, and HeLa cells growing in suspension culture.
Topics: Animals; Carcinoma, Hepatocellular; Cell Fractionation; Cells, Cultured; Cyclic AMP; HeLa Cells; In | 1972 |
An effect of dexamethasone on adenosine 3',5'-monophosphate content and adenosine 3',5'-monophosphate phosphodiesterase activity of cultured hepatoma cells.
Topics: Acid Phosphatase; Carcinoma, Hepatocellular; Cells, Cultured; Cyclic AMP; Dexamethasone; Epinephrine | 1972 |
Competitive inhibition of the transport of nucleosides, hypoxanthine, choline and deoxyglucose by theophylline, papaverine and prostaglandins.
Topics: Animals; Binding, Competitive; Biological Transport, Active; Carcinoma, Hepatocellular; Cells, Cultu | 1974 |
Tyrosine aminotransferase: enzyme induction independent of adenosine 3', 5'-monophosphate.
Topics: Adenine Nucleotides; Adenylyl Cyclases; Animals; Carcinoma, Hepatocellular; Culture Techniques; Cycl | 1968 |
Further studies on the induction of tyrosine aminotransferase in Morris hepatoma 9618A.
Topics: Amino Acids; Animals; Biological Transport; Carcinoma, Hepatocellular; Enzyme Induction; Glucagon; H | 1970 |
Induction of tyrosine aminotransferase and amino acid transport in Morris hepatomas and in adult and neonatal rat liver.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Animals, Newborn; Biological Transport; Carbon Isotopes | 1971 |
Naturally occurring and induced levels of amino acid transport and tyrosine aminotransferase in rats bearing Morris hepatomas.
Topics: Adrenal Glands; Adrenalectomy; Aminoisobutyric Acids; Animals; Biological Transport; Carbon Isotopes | 1972 |
Hormonal effect on tyrosine aminotransferase activities in Yoshida sarcoma and its variant lines.
Topics: Animals; Ascites; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cyclic AMP; Glucagon; | 1972 |