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theophylline and Bronchial Hyperreactivity

theophylline has been researched along with Bronchial Hyperreactivity in 38 studies

Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.

Research Excerpts

ExcerptRelevanceReference
"Twenty-four patients with mild-to-moderate asthma were studied using a randomized crossover design with the following three treatment blocks: (1) beclomethasone, 100 microg/d, alone for the first 2 weeks followed by 400 microg/d alone for the next 2 weeks; (2) beclomethasone, 100 microg/d, followed by 400 microg/d, with the addition of zafirlukast, 20 mg bid; (3) beclomethasone, 100 microg/d, followed by 400 microg/d, with the addition of theophylline, 200 to 300 mg bid."9.10Effects of adding either a leukotriene receptor antagonist or low-dose theophylline to a low or medium dose of inhaled corticosteroid in patients with persistent asthma. ( Dempsey, OJ; Fowler, SJ; Kennedy, G; Lipworth, BJ; Wilson, A, 2002)
"The effect of a single oral dose of cilostazol on BHR was studied in 10 elderly patients with clinically stable asthma, with a mean age of 59."9.08Effect of a phosphodiesterase 3 inhibitor, cilostazol, on bronchial hyperresponsiveness in elderly patients with asthma. ( Fujimura, M; Hashimoto, T; Kamio, Y; Matsuda, T; Myou, S, 1997)
"Previous studies evaluating spirometric values and symptoms have shown that once daily theophylline administered in the evening produces greater stabilisation of the airway function in asthmatic patients than the prototype theophylline given twice a day."9.08Effect of once daily and twice daily sustained release theophylline formulations on daytime variation of bronchial hyperresponsiveness in asthmatic patients. ( Biasin, C; Bonazza, L; Ferrari, M; Lampronti, G; Lo Cascio, V; Nacci, P; Olivieri, M; Talamini, G, 1997)
"Theophylline is a bronchodilator and immunomodulator drug which has recently been demonstrated to attenuate the recruitment and activation of inflammatory cells into lungs of asthmatics."9.08Effect of chronic theophylline treatment on the methacholine dose-response curve in allergic asthmatic subjects. ( Costello, JF; Cotter, T; Kilfeather, S; Page, CP; Spina, D; Sullivan, P, 1998)
"Mice rendered adenosine deaminase-deficient manifest an 'asthma' phenotype in the lungs that includes mast cell degranulation, eosinophilia, mucus hypersecretion and bronchial hyperresponsiveness."8.82The case for a role for adenosine in asthma: almost convincing? ( Fozard, JR, 2003)
"The effects of theophylline on allergen-induced airway obstruction and bronchial hyperresponsiveness were investigated in allergic rabbits."7.68Modification of allergen-induced airway obstruction and bronchial hyperresponsiveness in the allergic rabbit by theophylline aerosol. ( Ali, S; Metzger, WJ; Mustafa, SJ, 1992)
"The effects of prednisolone, salbutamol or theophylline treatment were studied in guinea pigs on bronchial hyperreactivity induced by chronic administration of PAF, (subsequently measuring respiratory flow after an intravenous injection of histamine) and the chemokinesis of leucocytes in vitro."7.68Effects of prednisolone, salbutamol and theophylline on bronchial hyperreactivity and leucocyte chemokinesis in guinea pigs. ( Berga, P; Fernández, AG; Gristwood, RW; Llupiá, J, 1991)
"Bronchial asthma is eosinophilic airway inflammation with enhanced airway responsiveness induced by eosinophilic granule proteins such as eosinophilic cationic protein (ECP) that are released from eosinophils."6.70[Effects of once-daily low-dose administration of sustained-release theophylline on airway inflammation and airway hyperresponsiveness in patients with asthma]. ( Terao, I, 2002)
" Once-daily theophylline when dosed in the evening not only controls nocturnal symptoms and improves airflow during the early morning hours, but decreases airway responsiveness to histamine as well."6.38Nocturnal asthma: mechanisms and the role of theophylline in treatment. ( Bush, RK, 1991)
"Theophylline has been used for decades in the treatment of chronic inflammatory airway diseases."5.43Bronchodilator and Anti-Inflammatory Action of Theophylline in a Model of Ovalbumin-Induced Allergic Inflammation. ( Kertys, M; Kosutova, P; Mikolka, P; Mokra, D; Mokry, J; Simekova, M; Urbanova, A, 2016)
"Sixty patients with cough due to BHR (shown by positive bronchial provocation test) were randomly divided into Chinese medicine group (n = 30) and control group (n = 30) to receive Bufeishenqingre decoction twice a day and 100 mg theophylline sustained-release capsules twice a day for one month, respectively."5.14[Effect of Bufeishenqingre decoction on bronchial hyperresponsiveness-induced cough]. ( Dou, YQ; Liu, Y; Yang, MH; Zhang, Y, 2010)
"Twenty-four patients with mild-to-moderate asthma were studied using a randomized crossover design with the following three treatment blocks: (1) beclomethasone, 100 microg/d, alone for the first 2 weeks followed by 400 microg/d alone for the next 2 weeks; (2) beclomethasone, 100 microg/d, followed by 400 microg/d, with the addition of zafirlukast, 20 mg bid; (3) beclomethasone, 100 microg/d, followed by 400 microg/d, with the addition of theophylline, 200 to 300 mg bid."5.10Effects of adding either a leukotriene receptor antagonist or low-dose theophylline to a low or medium dose of inhaled corticosteroid in patients with persistent asthma. ( Dempsey, OJ; Fowler, SJ; Kennedy, G; Lipworth, BJ; Wilson, A, 2002)
"The effect of a single oral dose of cilostazol on BHR was studied in 10 elderly patients with clinically stable asthma, with a mean age of 59."5.08Effect of a phosphodiesterase 3 inhibitor, cilostazol, on bronchial hyperresponsiveness in elderly patients with asthma. ( Fujimura, M; Hashimoto, T; Kamio, Y; Matsuda, T; Myou, S, 1997)
"Previous studies evaluating spirometric values and symptoms have shown that once daily theophylline administered in the evening produces greater stabilisation of the airway function in asthmatic patients than the prototype theophylline given twice a day."5.08Effect of once daily and twice daily sustained release theophylline formulations on daytime variation of bronchial hyperresponsiveness in asthmatic patients. ( Biasin, C; Bonazza, L; Ferrari, M; Lampronti, G; Lo Cascio, V; Nacci, P; Olivieri, M; Talamini, G, 1997)
"Theophylline is a bronchodilator and immunomodulator drug which has recently been demonstrated to attenuate the recruitment and activation of inflammatory cells into lungs of asthmatics."5.08Effect of chronic theophylline treatment on the methacholine dose-response curve in allergic asthmatic subjects. ( Costello, JF; Cotter, T; Kilfeather, S; Page, CP; Spina, D; Sullivan, P, 1998)
"Mice rendered adenosine deaminase-deficient manifest an 'asthma' phenotype in the lungs that includes mast cell degranulation, eosinophilia, mucus hypersecretion and bronchial hyperresponsiveness."4.82The case for a role for adenosine in asthma: almost convincing? ( Fozard, JR, 2003)
"In this study the effects of non-selective PDE inhibitors (theophylline and theobromine) and selective inhibitors of PDE 1, 3, 4 and 5 on cough, induced by citric acid, were evaluated."3.77The influence of the PDE inhibitors on cough reflex in guinea pigs. ( Mokry, J; Nosalova, G, 2011)
" Effects of cilostazol and vesnarinone (selective PDE III inhibitors), rolipram (selective PDE IV inhibitor) and theophylline (nonselective PDE inhibitor) on LPS-induced bronchial hyperreactivity were investigated in guinea pigs."3.70Effects of isoenzyme selective phosphodiesterase inhibitors on bacterial lipopolysaccharide-induced bronchial hyperreactivity in guinea pigs. ( Nagai, H; Tanaka, H; Uno, T, 1998)
"A new guinea pig model of allergic asthma was used to investigate the effects of low doses of the phosphodiesterase inhibitors, rolipram (phosphodiesterase IV selective), ORG 20241 (N-hydroxy-4-(3,4-dimethoxyphenyl)-thiazole-2-carboximidamide; dual phosphodiesterase III/IV inhibitor with some selectivity for the phosphodiesterase IV isoenzyme), and of theophylline (non-selective) on allergen-induced early and late phase asthmatic reactions, bronchial hyperreactivity to histamine inhalation, and airway inflammation."3.69Phosphodiesterase inhibitors reduce bronchial hyperreactivity and airway inflammation in unrestrained guinea pigs. ( Meurs, H; Olymulder, CG; Santing, RE; Van der Molen, K; Zaagsma, J, 1995)
" Allergic bronchial eosinophilia in guinea pigs was inhibited by orally administered dexamethasone and methylprednisolone."3.68Allergic bronchial eosinophilia: a therapeutic approach for the selection of potential bronchial anti-inflammatory drugs. ( Chand, N; De Vine, CL; Diamantis, W; Harrison, JE; Jakubicki, RG; Nolan, KW; Pillar, J; Rooney, SM; Sofia, RD, 1993)
"Recently, there has been an increasing interest in the involvement of adenosine as a mediator of allergic asthma."3.68Adenosine-induced bronchoconstriction in an allergic rabbit model: antagonism by theophylline aerosol. ( Ali, S; Metzger, WJ; Mustafa, SJ, 1992)
"The effects of theophylline on allergen-induced airway obstruction and bronchial hyperresponsiveness were investigated in allergic rabbits."3.68Modification of allergen-induced airway obstruction and bronchial hyperresponsiveness in the allergic rabbit by theophylline aerosol. ( Ali, S; Metzger, WJ; Mustafa, SJ, 1992)
"Described is a guinea pig model of allergic asthma, in which animals are sensitized by intraperitoneal injections of ovalbumin complexed with aluminum hydroxide to elicit an IgE response."3.68Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig. ( DeLeo, JJ; Handley, DA; Havill, AM, 1992)
"The effects of prednisolone, salbutamol or theophylline treatment were studied in guinea pigs on bronchial hyperreactivity induced by chronic administration of PAF, (subsequently measuring respiratory flow after an intravenous injection of histamine) and the chemokinesis of leucocytes in vitro."3.68Effects of prednisolone, salbutamol and theophylline on bronchial hyperreactivity and leucocyte chemokinesis in guinea pigs. ( Berga, P; Fernández, AG; Gristwood, RW; Llupiá, J, 1991)
" Therefore, we studied the effect of the beta2-agonist reproterol in combination with DSCG."2.71Effect of reproterol either alone or combined with disodium cromoglycate on airway responsiveness to methacholine. ( Jörres, RA; Kanniess, F; Magnussen, H, 2005)
"Bronchial asthma is eosinophilic airway inflammation with enhanced airway responsiveness induced by eosinophilic granule proteins such as eosinophilic cationic protein (ECP) that are released from eosinophils."2.70[Effects of once-daily low-dose administration of sustained-release theophylline on airway inflammation and airway hyperresponsiveness in patients with asthma]. ( Terao, I, 2002)
" Once-daily theophylline when dosed in the evening not only controls nocturnal symptoms and improves airflow during the early morning hours, but decreases airway responsiveness to histamine as well."2.38Nocturnal asthma: mechanisms and the role of theophylline in treatment. ( Bush, RK, 1991)
"Theophylline has been used for decades in the treatment of chronic inflammatory airway diseases."1.43Bronchodilator and Anti-Inflammatory Action of Theophylline in a Model of Ovalbumin-Induced Allergic Inflammation. ( Kertys, M; Kosutova, P; Mikolka, P; Mokra, D; Mokry, J; Simekova, M; Urbanova, A, 2016)
"Sevoflurane/olprinone treatment attenuated the bronchoconstriction induced by the highest dose of Ach with RL being significantly lower (0."1.37Synergic bronchodilator effects of a phosphodiesterase 3 inhibitor olprinone with a volatile anaesthetic sevoflurane in ovalbumin-sensitised guinea pigs. ( Iwasaki, S; Watanabe, A; Yamakage, M; Zhou, J, 2011)
"Theophylline is a drug that reduces the inflammatory effects of allergic asthma but is difficult to administer at an appropriate dosage without causing adverse side effects."1.33Thiolated chitosan nanoparticles enhance anti-inflammatory effects of intranasally delivered theophylline. ( Lee, DW; Lockey, RF; Mohapatra, SS; Shirley, SA, 2006)
"Aminophylline 25 mg/kg was given intraperitoneally to the group I animals and 5 mg/kg to group II animals."1.31Pulmonary function changes and immunomodulation of Th 2 cytokine expression induced by aminophylline after sensitization and allergen challenge in brown Norway rats. ( Chen, A; Liaw, SF; Lin, CC; Lin, CY, 2002)
" Acute airway hyperreactivity was evidenced by significant leftward shifts in dose-response curves to i."1.29Pulmonary antiallergic and bronchodilator effects of isozyme-selective phosphodiesterase inhibitors in guinea pigs. ( Howell, RE; Sickels, BD; Woeppel, SL, 1993)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's22 (57.89)18.2507
2000's10 (26.32)29.6817
2010's6 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tohda, Y1
Urbanova, A1
Kertys, M1
Simekova, M1
Mikolka, P1
Kosutova, P1
Mokra, D1
Mokry, J2
Zhang, Y1
Yang, MH1
Dou, YQ1
Liu, Y1
Mizutani, N1
Inui, S1
Yoshino, S1
Nabe, T1
Nosalova, G1
Zhou, J1
Iwasaki, S1
Watanabe, A1
Yamakage, M1
Dempsey, OJ1
Fowler, SJ1
Wilson, A1
Kennedy, G1
Lipworth, BJ1
Balfour-Lynn, IM1
Elborn, JS1
Sakai, J1
Oike, M1
Hirakawa, M1
Ito, Y1
Fozard, JR1
Fukkuda, T1
Kanniess, F1
Jörres, RA1
Magnussen, H1
Salmeron, S1
Lee, DW1
Shirley, SA1
Lockey, RF1
Mohapatra, SS1
Santing, RE1
Olymulder, CG1
Van der Molen, K1
Meurs, H1
Zaagsma, J1
Ferrari, M2
Olivieri, M2
Lampronti, G2
Biasin, C2
Lo Cascio, V2
Ibáñez, MD1
Laso, MT1
Alonso, E1
Muñoz, MC1
Sastre, J1
Murphy, S1
Kelly, HW1
Chand, N1
Harrison, JE1
Rooney, SM1
Nolan, KW1
De Vine, CL1
Jakubicki, RG1
Pillar, J1
Diamantis, W1
Sofia, RD1
Howell, RE1
Sickels, BD1
Woeppel, SL1
Song, P1
Milanese, M1
Crimi, E1
Rehder, K1
Brusasco, V1
Kagoshima, M1
Tomomatsu, N1
Iwahisa, Y1
Yamaguchi, S1
Matsuura, M1
Kawakami, Y1
Terasawa, M1
Fujimura, M1
Kamio, Y1
Myou, S1
Hashimoto, T1
Matsuda, T1
Bonazza, L1
Nacci, P1
Talamini, G1
Uno, T1
Tanaka, H1
Nagai, H1
Page, CP1
Cotter, T1
Kilfeather, S1
Sullivan, P1
Spina, D1
Costello, JF1
Abraham, WM1
Sabater, JR1
Szelenyi, S1
Bähre, M1
Koshino, T1
Lin, CC1
Lin, CY1
Liaw, SF1
Chen, A1
Terao, I1
Ali, S2
Mustafa, SJ2
Metzger, WJ2
Handley, DA1
DeLeo, JJ1
Havill, AM1
Shibasaki, M1
Takeda, K1
Sumazaki, R1
Nogami, T1
Takita, H1
Martin, RJ1
Bush, RK1
Llupiá, J1
Fernández, AG1
Berga, P1
Gristwood, RW1

Reviews

8 reviews available for theophylline and Bronchial Hyperreactivity

ArticleYear
[My research on asthma today and in the future].
    Arerugi = [Allergy], 2013, Volume: 62, Issue:11

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; D

2013
"CF asthma": what is it and what do we do about it?
    Thorax, 2002, Volume: 57, Issue:8

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Bronchial Hyperreactivity; Bronchodila

2002
The case for a role for adenosine in asthma: almost convincing?
    Current opinion in pharmacology, 2003, Volume: 3, Issue:3

    Topics: Adenosine; Adenosine Deaminase; Animals; Asthma; Asthma, Exercise-Induced; Bronchial Hyperreactivity

2003
[Recent study on pathogenesis of bronchial asthma and the therapeutic strategy].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2004, Mar-10, Volume: 93, Issue:3

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Anti-Asthmatic Agents; Anti-Inflamm

2004
Asthma, inflammation, and airway hyperresponsiveness in children.
    Current opinion in pediatrics, 1993, Volume: 5, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Allergens; Anti-Inflammatory Agents; Asthma; Bron

1993
[Diagnosis and management of asthma].
    Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57, Issue:9

    Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Anti-Inflammatory Agents

1999
Nocturnal asthma.
    Clinics in chest medicine, 1992, Volume: 13, Issue:3

    Topics: Adrenal Cortex Hormones; Asthma; Bronchial Hyperreactivity; Circadian Rhythm; Gastroesophageal Reflu

1992
Nocturnal asthma: mechanisms and the role of theophylline in treatment.
    Postgraduate medical journal, 1991, Volume: 67 Suppl 4

    Topics: Asthma; Bronchial Hyperreactivity; Circadian Rhythm; Humans; Lung; Theophylline

1991

Trials

9 trials available for theophylline and Bronchial Hyperreactivity

ArticleYear
[Effect of Bufeishenqingre decoction on bronchial hyperresponsiveness-induced cough].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2010, Volume: 30, Issue:9

    Topics: Adult; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchodilator Agents; Cough; Drugs,

2010
Effects of adding either a leukotriene receptor antagonist or low-dose theophylline to a low or medium dose of inhaled corticosteroid in patients with persistent asthma.
    Chest, 2002, Volume: 122, Issue:1

    Topics: Administration, Inhalation; Administration, Oral; Adult; Anti-Asthmatic Agents; Asthma; Beclomethaso

2002
Effect of reproterol either alone or combined with disodium cromoglycate on airway responsiveness to methacholine.
    Pulmonary pharmacology & therapeutics, 2005, Volume: 18, Issue:5

    Topics: Administration, Inhalation; Adolescent; Adult; Bronchial Hyperreactivity; Bronchial Provocation Test

2005
Effect of three different doses of a slow-release theophylline formulation on bronchial response to inhaled methacholine in asthmatic patients.
    Respiration; international review of thoracic diseases, 1995, Volume: 62, Issue:2

    Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Delayed-Action Preparations;

1995
Effect of theophylline on airway responsiveness to methacholine and on exercise-induced bronchoconstriction.
    Annals of allergy, 1994, Volume: 73, Issue:4

    Topics: Adolescent; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronch

1994
Effect of a phosphodiesterase 3 inhibitor, cilostazol, on bronchial hyperresponsiveness in elderly patients with asthma.
    International archives of allergy and immunology, 1997, Volume: 114, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Aged; Asthma; Bronchial Hyperreactivity;

1997
Effect of once daily and twice daily sustained release theophylline formulations on daytime variation of bronchial hyperresponsiveness in asthmatic patients.
    Thorax, 1997, Volume: 52, Issue:11

    Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Br

1997
Effect of chronic theophylline treatment on the methacholine dose-response curve in allergic asthmatic subjects.
    The European respiratory journal, 1998, Volume: 12, Issue:1

    Topics: Adult; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchodil

1998
[Effects of once-daily low-dose administration of sustained-release theophylline on airway inflammation and airway hyperresponsiveness in patients with asthma].
    Arerugi = [Allergy], 2002, Volume: 51, Issue:4

    Topics: Administration, Oral; Adult; Asthma; Blood Proteins; Bronchial Hyperreactivity; Bronchodilator Agent

2002

Other Studies

21 other studies available for theophylline and Bronchial Hyperreactivity

ArticleYear
Bronchodilator and Anti-Inflammatory Action of Theophylline in a Model of Ovalbumin-Induced Allergic Inflammation.
    Advances in experimental medicine and biology, 2016, Volume: 935

    Topics: Airway Resistance; Animals; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchoconstriction

2016
Intratracheal sensitization/challenge-induced biphasic asthmatic response and airway hyperresponsiveness in guinea pigs.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:12

    Topics: Airway Resistance; Animals; Anti-Asthmatic Agents; Antigens; Asthma; Bronchial Hyperreactivity; Chro

2010
The influence of the PDE inhibitors on cough reflex in guinea pigs.
    Bratislavske lekarske listy, 2011, Volume: 112, Issue:3

    Topics: Animals; Antitussive Agents; Bronchial Hyperreactivity; Citric Acid; Cough; Guinea Pigs; Male; Ovalb

2011
Synergic bronchodilator effects of a phosphodiesterase 3 inhibitor olprinone with a volatile anaesthetic sevoflurane in ovalbumin-sensitised guinea pigs.
    European journal of anaesthesiology, 2011, Volume: 28, Issue:7

    Topics: Acetylcholine; Airway Resistance; Anesthetics, Inhalation; Animals; Bronchial Hyperreactivity; Bronc

2011
Theophylline and cAMP inhibit lysophosphatidic acid-induced hyperresponsiveness of bovine tracheal smooth muscle cells.
    The Journal of physiology, 2003, May-15, Volume: 549, Issue:Pt 1

    Topics: Actins; Animals; Bronchial Hyperreactivity; Bronchodilator Agents; Calcium; Cattle; Cells, Cultured;

2003
[Poor compliance: what are the sequelae for the asthmatic patient?].
    Revue de pneumologie clinique, 2005, Volume: 61 Spec No 1

    Topics: Acute Disease; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adrenergic

2005
Thiolated chitosan nanoparticles enhance anti-inflammatory effects of intranasally delivered theophylline.
    Respiratory research, 2006, Aug-24, Volume: 7

    Topics: Administration, Intranasal; Animals; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Chitosan;

2006
Phosphodiesterase inhibitors reduce bronchial hyperreactivity and airway inflammation in unrestrained guinea pigs.
    European journal of pharmacology, 1995, Feb-24, Volume: 275, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Inhalation; Analysis of Variance; Animals; Asth

1995
Allergic bronchial eosinophilia: a therapeutic approach for the selection of potential bronchial anti-inflammatory drugs.
    Allergy, 1993, Volume: 48, Issue:8

    Topics: Albuterol; Allergens; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoa

1993
Pulmonary antiallergic and bronchodilator effects of isozyme-selective phosphodiesterase inhibitors in guinea pigs.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Aminophylline; Animals; Bronchial Hyperreactivity; Bronchoconstriction; Bronchodilator Agents; Guine

1993
Allergen challenge of passively sensitized human bronchi alters M2 and beta2 receptor function.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:4

    Topics: Adrenergic beta-Agonists; Adult; Aged; Albuterol; Allergens; Animals; Asthma; Bronchi; Bronchial Hyp

1997
Suppressive effects of Y-24180, a receptor antagonist to platelet activating factor (PAF), on antigen-induced asthmatic responses in guinea pigs.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46, Issue:4

    Topics: Administration, Oral; Aerosols; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Azepin

1997
Effects of isoenzyme selective phosphodiesterase inhibitors on bacterial lipopolysaccharide-induced bronchial hyperreactivity in guinea pigs.
    General pharmacology, 1998, Volume: 30, Issue:2

    Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cilostazol; Guinea

1998
Comparative effects of a fixed combination of reproterol hydrochloride and disodium cromoglycate with each agent alone on antigen-induced airway responses in sheep.
    Pulmonary pharmacology & therapeutics, 1998, Volume: 11, Issue:4

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aerosols; Airway Resistance; Animals; Anti-All

1998
Pulmonary function changes and immunomodulation of Th 2 cytokine expression induced by aminophylline after sensitization and allergen challenge in brown Norway rats.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 88, Issue:2

    Topics: Allergens; Aminophylline; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid;

2002
Adenosine-induced bronchoconstriction in an allergic rabbit model: antagonism by theophylline aerosol.
    Agents and actions, 1992, Volume: 37, Issue:3-4

    Topics: Adenosine; Aerosols; Anesthesia; Animals; Asthma; Bronchial Hyperreactivity; Histamine; Pollen; Rabb

1992
Modification of allergen-induced airway obstruction and bronchial hyperresponsiveness in the allergic rabbit by theophylline aerosol.
    Agents and actions, 1992, Volume: 37, Issue:3-4

    Topics: Aerosols; Airway Obstruction; Airway Resistance; Allergens; Animals; Asthma; Bronchial Hyperreactivi

1992
Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig.
    Agents and actions, 1992, Volume: 37, Issue:3-4

    Topics: Acetylcholine; Aerosols; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Diphenhydramine; Gui

1992
Premenstrual asthma with seasonal variation.
    Annals of allergy, 1992, Volume: 68, Issue:4

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Allergens; Animals; Antibodies; Antigen

1992
[Diagnosis, physiopathology and therapy of bronchial asthma: discussion].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Jun-10, Volume: 81, Issue:6

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Asthma; Bronchial Hyperreactivity; Desensitiza

1992
Effects of prednisolone, salbutamol and theophylline on bronchial hyperreactivity and leucocyte chemokinesis in guinea pigs.
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:8

    Topics: Albuterol; Animals; Asthma; Bronchial Hyperreactivity; Chemotaxis, Leukocyte; Guinea Pigs; Male; Pla

1991