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theophylline and Breast Cancer

theophylline has been researched along with Breast Cancer in 20 studies

Research Excerpts

ExcerptRelevanceReference
"Theophylline can augment radioiodide uptake in breast cancer cells and NIS gene-transduced cancer cells through the upregulation of NIS expression."7.75Effects of theophylline on radioiodide uptake in MCF-7 breast cancer and NIS gene-transduced SNU-C5 colon cancer cells. ( Jung, KH; Ko, BH; Lee, KH; Paik, JY; Park, BN; Yoon, JK, 2009)
"Theophylline was absorbed rapidly in all subjects and within 2 h reached comparable peak concentrations in both groups (cancer patients: 57."6.67The disposition of theophylline in patients with lung and breast cancer. ( Attardo-Parrinello, G; Barzaghi, N; Corasaniti, MT; Crema, F; Gatti, G; Perucca, E, 1994)
"Theophylline-treated cancer cells were analyzed for the transcript and protein expression of candidate apoptotic genes such as TNFR1, caspase-8, -9, -3 using qPCR and immunoblotting, respectively."5.72Reactive oxygen species-dependent upregulation of death receptor, tumor necrosis factor receptor 1, is responsible for theophylline-mediated cytotoxicity in MDA-MB-231 breast cancer cells. ( Dutta, S; Ghosal, N; Pal, A; Pal, R; Tapadar, P, 2022)
"Antipyrine was given as a single test dose before and after 3 mo of AG treatment, whereas theophylline and digitoxin kinetics were investigated at steady state in patients receiving these drugs therapeutically before and after AG therapy."5.27Effect of aminoglutethimide on antipyrine, theophylline, and digitoxin disposition in breast cancer. ( Bakke, OM; Kvinnsland, S; Lønning, E, 1984)
"Theophylline can augment radioiodide uptake in breast cancer cells and NIS gene-transduced cancer cells through the upregulation of NIS expression."3.75Effects of theophylline on radioiodide uptake in MCF-7 breast cancer and NIS gene-transduced SNU-C5 colon cancer cells. ( Jung, KH; Ko, BH; Lee, KH; Paik, JY; Park, BN; Yoon, JK, 2009)
"Aminoglutethimide is an aromatase inhibitor that is successfully used for endocrine treatment of advanced breast cancer."3.68Aminoglutethimide enzyme induction: pharmacological and endocrinological implications. ( Lønning, PE, 1990)
"Comparative investigation of subpopulations and functional properties of lymphocytes isolated from the tumour tissue (TTL) as well as of lymphocytes of the peripheral blood (PBL) of 11 lung cancer patients and 18 breast cancer patients has shown that an increase in the quantity of theophylline-sensitive cells (suppressors and killers) is characteristic of TTL."3.67[Comparative study of the lymphocyte surface receptors isolated from the blood and tissue of malignant tumors]. ( Bilynskiĭ, BT; Volod'ko, NA, 1986)
"MCF-7 human breast cancer cells that were treated for one hour prior to X irradiation with the cyclic AMP-inducing agent 1-methyl-3-isobutylxanthine displayed a slight but significant increase in surviving fraction over untreated controls at each radiation dose level."3.66Work in progress: radioprotection of human breast cancer cells by elevation of intracellular cyclic AMP. ( Gifford, L; Griem, K; Little, JB; Umans, RS; Weichselbaum, RR, 1983)
"Theophylline was absorbed rapidly in all subjects and within 2 h reached comparable peak concentrations in both groups (cancer patients: 57."2.67The disposition of theophylline in patients with lung and breast cancer. ( Attardo-Parrinello, G; Barzaghi, N; Corasaniti, MT; Crema, F; Gatti, G; Perucca, E, 1994)
"Theophylline-treated cancer cells were analyzed for the transcript and protein expression of candidate apoptotic genes such as TNFR1, caspase-8, -9, -3 using qPCR and immunoblotting, respectively."1.72Reactive oxygen species-dependent upregulation of death receptor, tumor necrosis factor receptor 1, is responsible for theophylline-mediated cytotoxicity in MDA-MB-231 breast cancer cells. ( Dutta, S; Ghosal, N; Pal, A; Pal, R; Tapadar, P, 2022)
"Antipyrine was given as a single test dose before and after 3 mo of AG treatment, whereas theophylline and digitoxin kinetics were investigated at steady state in patients receiving these drugs therapeutically before and after AG therapy."1.27Effect of aminoglutethimide on antipyrine, theophylline, and digitoxin disposition in breast cancer. ( Bakke, OM; Kvinnsland, S; Lønning, E, 1984)
"The analysis of 178 cases of stage I-II breast cancer showed morphological features of local cell-mediated immune reactions to be of limited prognostic value."1.27[Local cellular immune reactions in cancer patients]. ( Bilynskiĭ, BT; Vasil'ev, NV; Volod'ko, NA, 1988)
"Tumours associated with bone resorption had higher concentrations of prostaglandin E in culture media at the end of incubation than did non-resorbers."1.26Prostaglandins as mediators of bone resorption in renal and breast tumours. ( Atkins, D; Greaves, M; Ibbotson, KJ; Martin, TJ, 1980)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199012 (60.00)18.7374
1990's2 (10.00)18.2507
2000's3 (15.00)29.6817
2010's1 (5.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Fu, CW1
Tsai, HE1
Chen, WS1
Chang, TT1
Chen, CL1
Hsiao, PW1
Li, WS1
Tapadar, P1
Pal, A1
Ghosal, N1
Dutta, S1
Pal, R1
Hashemi-Niasari, F1
Rabbani-Chadegani, A1
Razmi, M1
Fallah, S1
Yoon, JK1
Park, BN1
Paik, JY1
Jung, KH1
Ko, BH1
Lee, KH1
BRENNIG, K1
Notter, G1
Tsioulias, T1
Asard, PE1
Griem, K1
Weichselbaum, RR1
Umans, RS1
Gifford, L1
Little, JB1
Lønning, E1
Kvinnsland, S1
Bakke, OM1
Greaves, M1
Ibbotson, KJ1
Atkins, D1
Martin, TJ1
Corasaniti, MT1
Gatti, G1
Crema, F1
Attardo-Parrinello, G1
Barzaghi, N1
Perucca, E1
Slotkin, TA2
Seidler, FJ2
Crumpton, TL1
Tchao, R1
Leighton, J1
Shafie, S1
Brooks, SC1
Honn, KV1
Chavin, W1
Hussa, RO1
Pattillo, RA1
Ruckert, AC1
Scheuermann, KW1
Lønning, PE1
Bilynskiĭ, BT2
Vasil'ev, NV1
Volod'ko, NA2
Wolberg, WH1

Trials

1 trial available for theophylline and Breast Cancer

ArticleYear
The disposition of theophylline in patients with lung and breast cancer.
    Drugs under experimental and clinical research, 1994, Volume: 20, Issue:3

    Topics: Adult; Biotransformation; Breast Neoplasms; Female; Half-Life; Humans; Immunoenzyme Techniques; Inte

1994

Other Studies

19 other studies available for theophylline and Breast Cancer

ArticleYear
Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis.
    Journal of medicinal chemistry, 2021, 01-14, Volume: 64, Issue:1

    Topics: Animals; Animals, Genetically Modified; Breast Neoplasms; Catalysis; Cell Line, Tumor; Enzyme Inhibi

2021
Reactive oxygen species-dependent upregulation of death receptor, tumor necrosis factor receptor 1, is responsible for theophylline-mediated cytotoxicity in MDA-MB-231 breast cancer cells.
    Anti-cancer drugs, 2022, 09-01, Volume: 33, Issue:8

    Topics: Apoptosis; Breast Neoplasms; Caspase 8; Cathepsins; Cell Line, Tumor; Cell Survival; Female; Humans;

2022
Synergy of theophylline reduces necrotic effect of berberine, induces cell cycle arrest and PARP, HMGB1, Bcl-2 family mediated apoptosis in MDA-MB-231 breast cancer cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 106

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Berberine; Br

2018
Effects of theophylline on radioiodide uptake in MCF-7 breast cancer and NIS gene-transduced SNU-C5 colon cancer cells.
    Cancer biotherapy & radiopharmaceuticals, 2009, Volume: 24, Issue:2

    Topics: Biological Transport; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Genetic Therapy; Humans

2009
[CLINICAL STUDIES WITH VOYAL IN RADIATION INJURIES].
    Wiener medizinische Wochenschrift (1946), 1963, Aug-31, Volume: 113

    Topics: Breast Neoplasms; Diphenhydramine; Female; Humans; Lung Neoplasms; Radiation Injuries; Theophylline;

1963
Effect of complamin on radiation-induced erythema.
    Acta radiologica: therapy, physics, biology, 1967, Volume: 6, Issue:4

    Topics: Breast Neoplasms; Erythema; Female; Humans; Hyperemia; Nicotinic Acids; Oxygen Consumption; Radiatio

1967
Work in progress: radioprotection of human breast cancer cells by elevation of intracellular cyclic AMP.
    Radiology, 1983, Volume: 148, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Breast Neoplasms; Cell Line; Cell Survival; Cyclic AMP; Female; Humans;

1983
Effect of aminoglutethimide on antipyrine, theophylline, and digitoxin disposition in breast cancer.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:6

    Topics: Adult; Aged; Aminoglutethimide; Antipyrine; Breast Neoplasms; Chromatography, High Pressure Liquid;

1984
Prostaglandins as mediators of bone resorption in renal and breast tumours.
    Clinical science (London, England : 1979), 1980, Volume: 58, Issue:3

    Topics: Animals; Biological Assay; Bone Resorption; Breast Neoplasms; Culture Techniques; Female; Humans; In

1980
Antimitotic and cytotoxic effects of theophylline in MDA-MB-231 human breast cancer cells.
    Breast cancer research and treatment, 2000, Volume: 64, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Antineoplastic Agents; Breast Neoplasms; Cell Adhesi

2000
Generation of reactive oxygen species by xanthine derivatives in MDA-MB-231 human breast cancer cells.
    Breast cancer research and treatment, 2001, Volume: 66, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Breast Neoplasms; Female; Humans; Phosphodiesterase Inhibitors; Reactiv

2001
Inhibitory effect of dibutyryl cyclic AMP and theophylline on the aggregation of human brest tumour cell line BT-20.
    Nature, 1976, Jan-22, Volume: 259, Issue:5540

    Topics: Breast Neoplasms; Bucladesine; Cell Aggregation; Cell Line; Depression, Chemical; Theophylline

1976
Effect of prolactin on growth and the estrogen receptor level of human breast cancer cells (MCF-7).
    Cancer research, 1977, Volume: 37, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Breast Neoplasms; Bucladesine; Cell Division; Cell Nucleus; Cel

1977
In vitro effects of theophylline and aminogluthetimide upon basal and ACTH induced cAMP levels and steroid output by the normal human adrenal gland.
    Acta endocrinologica, 1978, Volume: 88, Issue:2

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Breast Neoplasms; Cycli

1978
Effects of butyrate and dibutyryl cyclic AMP on hCG-secreting trophoblastic and non-trophoblastic cells.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:1

    Topics: Adult; Breast Neoplasms; Bucladesine; Butyrates; Carcinoma, Squamous Cell; Cell Line; Choriocarcinom

1978
Aminoglutethimide enzyme induction: pharmacological and endocrinological implications.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:4

    Topics: Aminoglutethimide; Antipyrine; Aromatase Inhibitors; Breast Neoplasms; Digitoxin; Drug Interactions;

1990
[Local cellular immune reactions in cancer patients].
    Voprosy onkologii, 1988, Volume: 34, Issue:7

    Topics: Aged; Breast Neoplasms; Female; Humans; Lung Neoplasms; Lymphocytes; Middle Aged; Prognosis; Rosette

1988
[Comparative study of the lymphocyte surface receptors isolated from the blood and tissue of malignant tumors].
    Eksperimental'naia onkologiia, 1986, Volume: 8, Issue:3

    Topics: Adult; Aged; Breast Neoplasms; Humans; Lung Neoplasms; Lymphocytes; Middle Aged; Receptors, Immunolo

1986
Inhibition of leukocyte migration by human tumors. Effect on patient survival.
    Archives of surgery (Chicago, Ill. : 1960), 1974, Volume: 109, Issue:2

    Topics: Breast Neoplasms; Bucladesine; Cell Migration Inhibition; Colonic Neoplasms; Culture Media; Culture

1974