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theophylline and Bone Loss, Osteoclastic

theophylline has been researched along with Bone Loss, Osteoclastic in 20 studies

Research Excerpts

ExcerptRelevanceReference
"Hypercalcemia and hypercalciuria observed both in humans and in animals who were on long-term theophylline therapy, prompted us to investigate whether oral theophylline treatment at optimal doses causes any adverse side effects on bone metabolism in mild asthmatics."7.70Evaluation of the effect of low-dose oral theophylline therapy on some bone turnover markers and serum prolidase I activity in mild asthmatics. ( Büyüköztürk, S; Gürdöl, F; Kolanci, C; Oner, P; Oner-Iyidon, Y, 1999)
"Hypercalcemia and hypercalciuria observed both in humans and in animals who were on long-term theophylline therapy, prompted us to investigate whether oral theophylline treatment at optimal doses causes any adverse side effects on bone metabolism in mild asthmatics."3.70Evaluation of the effect of low-dose oral theophylline therapy on some bone turnover markers and serum prolidase I activity in mild asthmatics. ( Büyüköztürk, S; Gürdöl, F; Kolanci, C; Oner, P; Oner-Iyidon, Y, 1999)
"In indomethacin-treated bones, however, caffeine potentiated the stimulatory effect on 45Ca release induced by choleratoxin and forskolin."1.28Caffeine has the capacity to stimulate calcium release in organ culture of neonatal mouse calvaria. ( Lerner, UH; Mellström, D, 1992)
"The effect on cyclic AMP levels and bone resorption by two methylxanthine cyclic AMP phosphodiesterase (PDE) inhibitors, isobutyl-methylxanthine (IBMX) and theophylline, and two non-xanthine PDE inhibitors, Ro 20-1724 and rolipram, was studied in cultured mouse calvarial bones."1.27Delayed stimulation of bone resorption in vitro by phosphodiesterase inhibitors requires the presence of adenylate cyclase stimulation. ( Fredholm, BB; Lerner, UH; Ransjö, M, 1988)
"Tumours associated with bone resorption had higher concentrations of prostaglandin E in culture media at the end of incubation than did non-resorbers."1.26Prostaglandins as mediators of bone resorption in renal and breast tumours. ( Atkins, D; Greaves, M; Ibbotson, KJ; Martin, TJ, 1980)
"In 9/13 cases significant bone resorption occurred whilst in no case did control kidney cause significant resorption."1.26Secretion of prostaglandins as bone-resorbing agents by renal cortical carcinoma in culture. ( Atkins, D; Hammonds, JC; Hillier, K; Hunt, NH; Ibbotson, KJ; Martin, TJ, 1977)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199015 (75.00)18.7374
1990's5 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lerner, U3
Gustafson, GT1
Greaves, M1
Ibbotson, KJ2
Atkins, D2
Martin, TJ2
Amano, S1
Naganuma, K1
Kawata, Y1
Kawakami, K1
Kitano, S1
Hanazawa, S1
Oner, P1
Gürdöl, F1
Oner-Iyidon, Y1
Kolanci, C1
Büyüköztürk, S1
Yu, JH1
Wells, H1
Ryan, WJ1
Lloyd, WS1
Hillier, K1
Hunt, NH1
Hammonds, JC1
Lerner, UH3
Mellström, D1
Reid, IR1
Lowe, C1
Cornish, J1
Gray, DH1
Skinner, SJ1
Dewhirst, FE1
Ago, JM1
Stashenko, P1
Ransjö, M2
Fredholm, BB3
Sahlberg, K1
Rasmussen, H1
Pechet, M1
Fast, D1
Vaes, G1
Johnston, CC1
Grinnan, EL1
Wilson, HC1
Boder, GB1
Herrmann-Erlee, MP1
Avery, SH1
Bell, NH1
Stern, PH1
Raisz, LG1
Trummel, CL1
Simmons, H1
Luthman, J1
Jonson, G1
Persson, J1

Other Studies

20 other studies available for theophylline and Bone Loss, Osteoclastic

ArticleYear
Inhibition of bone resorption and lysosomal enzyme release from calvarial bones cultured for 24 hours: synergism between cyclic AMP analogues and phosphodiesterase inhibitors.
    Acta endocrinologica, 1980, Volume: 94, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bone and Bones; Bone Resorption; Bucladesine; Calcium; Cyclic

1980
Delayed stimulatory effect of cyclic AMP on bone resorption in vitro.
    Acta endocrinologica, 1981, Volume: 97, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bone Resorption; Bucladesine; Cells, Cultured; Mice; Parathyro

1981
Prostaglandins as mediators of bone resorption in renal and breast tumours.
    Clinical science (London, England : 1979), 1980, Volume: 58, Issue:3

    Topics: Animals; Biological Assay; Bone Resorption; Breast Neoplasms; Culture Techniques; Female; Humans; In

1980
Prostaglandin E2 stimulates osteoclast formation via endogenous IL-1 beta expressed through protein kinase A.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Mar-01, Volume: 156, Issue:5

    Topics: 24,25-Dihydroxyvitamin D 3; Animals; Bone Resorption; Cell Differentiation; Cells, Cultured; Cyclic

1996
Evaluation of the effect of low-dose oral theophylline therapy on some bone turnover markers and serum prolidase I activity in mild asthmatics.
    Pharmacological research, 1999, Volume: 40, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Alkaline Phosphatase; Amino Acids; Asthma; Biomarkers

1999
Effects of prostaglandins and other drugs on the cyclic AMP content of cultured bone cells.
    Prostaglandins, 1976, Volume: 12, Issue:4

    Topics: Animals; Animals, Newborn; Bone and Bones; Bone Resorption; Calcimycin; Calcitonin; Cells, Cultured;

1976
Secretion of prostaglandins as bone-resorbing agents by renal cortical carcinoma in culture.
    British journal of cancer, 1977, Volume: 36, Issue:5

    Topics: Animals; Bone Resorption; Cyclic AMP; Humans; In Vitro Techniques; Indomethacin; Kidney Cortex; Kidn

1977
Caffeine has the capacity to stimulate calcium release in organ culture of neonatal mouse calvaria.
    Calcified tissue international, 1992, Volume: 51, Issue:6

    Topics: Animals; Animals, Newborn; Bone and Bones; Bone Resorption; Caffeine; Calcium; Dose-Response Relatio

1992
Adenylate cyclase blockers dissociate PTH-stimulated bone resorption from cAMP production.
    The American journal of physiology, 1990, Volume: 258, Issue:4 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylyl Cyclase Inhibitors; Animals; Bone and Bones; Bone Res

1990
Interleukin 1 interacts synergistically with forskolin and isobutylmethylxanthine in stimulating bone resorption in organ culture.
    Calcified tissue international, 1990, Volume: 47, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bone and Bones; Bone Resorption; Colforsin; Drug Synergism; In

1990
Comparative study of the effects of cyclic nucleotide phosphodiesterase inhibitors on bone resorption and cyclic AMP formation in vitro.
    Biochemical pharmacology, 1986, Dec-01, Volume: 35, Issue:23

    Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl

1986
Delayed stimulation of bone resorption in vitro by phosphodiesterase inhibitors requires the presence of adenylate cyclase stimulation.
    Bone and mineral, 1988, Volume: 3, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Anim

1988
Characterization of adenosine receptors in bone. Studies on the effect of adenosine analogues on cyclic AMP formation and bone resorption in cultured mouse calvaria.
    Acta physiologica Scandinavica, 1987, Volume: 131, Issue:2

    Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bone and Bones; B

1987
Effect of dibutyryl cyclic adenosine 3',5'-monophosphate, theophylline, and other nucleotides upon calcium and phosphate metabolism.
    The Journal of clinical investigation, 1968, Volume: 47, Issue:8

    Topics: Adenine Nucleotides; Animals; Bone Resorption; Butyrates; Calcitonin; Calcium; Cyclic AMP; Hydroxypr

1968
Parathyroid hormone-like action of N6-2'-O-dibutyryladenosine-3'5' (cyclic)-monophosphate on bone explants in tissue culture.
    Nature, 1968, Aug-31, Volume: 219, Issue:5157

    Topics: Acid Phosphatase; Adenine Nucleotides; Animals; Bone and Bones; Bone Resorption; Butyrates; Calcium;

1968
Protamine-induced hypocalcemia.
    Endocrinology, 1970, Volume: 87, Issue:6

    Topics: Animals; Bone Resorption; Calcium; Calcium Isotopes; Culture Techniques; Cyclic AMP; Depression, Che

1970
Studies on the role of cyclic AMP in parathyroid hormone-induced embryonic bone resorption.
    The Journal of endocrinology, 1970, Volume: 48, Issue:4

    Topics: Adenine Nucleotides; Animals; Bone Resorption; Calcium; Cyclic AMP; Embryo, Mammalian; In Vitro Tech

1970
Inhibition of the hypercalcemic action of vitamin D 3 with imidazole.
    Endocrinology, 1971, Volume: 89, Issue:4

    Topics: Animals; Bone and Bones; Bone Resorption; Calcium; Calcium Isotopes; Cholecalciferol; Culture Techni

1971
Induction of bone resorption in tissue culture. Prolonged response after brief exposure to parathyroid hormone or 25-hydroxycholecalciferol.
    Endocrinology, 1972, Volume: 90, Issue:3

    Topics: Alkaloids; Animals; Bone Resorption; Calcitonin; Calcium; Calcium Isotopes; Cholecalciferol; Cyclic

1972
Theophylline-induced hypocalcemia in sheep.
    Acta veterinaria Scandinavica, 1972, Volume: 13, Issue:4

    Topics: Animals; Bone and Bones; Bone Resorption; Calcium; Cyclic AMP; Fatty Acids, Nonesterified; Female; H

1972