theophylline has been researched along with Asphyxia Neonatorum in 24 studies
Asphyxia Neonatorum: Respiratory failure in the newborn. (Dorland, 27th ed)
Excerpt | Relevance | Reference |
---|---|---|
"To evaluate the effects of prophylactic theophylline in renal function and survival rates of asphyxiated newborns." | 9.12 | Effectiveness of theophylline administration in neonates with perinatal asphyxia: a meta-analysis. ( Bellos, I; Pandita, A; Yachha, M, 2021) |
"To compare the efficacy and safety of theophylline or aminophylline for prevention of acute kidney injury (AKI) in neonates and children." | 9.01 | Theophylline and aminophylline for prevention of acute kidney injury in neonates and children: a systematic review. ( Bhatt, GC; Bitzan, M; Das, RR; Gogia, P, 2019) |
"The effect of theophylline on cerebral blood flow (CBF), oxygen transport, and energy metabolism was investigated during and following brief episodes of asphyxia." | 7.69 | Cerebral blood flow and metabolism during repeated asphyxias in newborn piglets: influence of theophylline. ( Delivoria-Papadopoulos, M; Goplerud, JM, 1994) |
"The simultaneous determination of caffeine and theophylline plasmatic levels has been proposed when the later is used in the treatment of the newborn's apnea." | 7.68 | [Importance of monitoring theophylline and caffeine plasma levels in the management of neonatal apnea]. ( Sacristán del Castillo, JA; Soto Alvarez, J, 1991) |
"To evaluate the effects of prophylactic theophylline in renal function and survival rates of asphyxiated newborns." | 5.12 | Effectiveness of theophylline administration in neonates with perinatal asphyxia: a meta-analysis. ( Bellos, I; Pandita, A; Yachha, M, 2021) |
"To compare the efficacy and safety of theophylline or aminophylline for prevention of acute kidney injury (AKI) in neonates and children." | 5.01 | Theophylline and aminophylline for prevention of acute kidney injury in neonates and children: a systematic review. ( Bhatt, GC; Bitzan, M; Das, RR; Gogia, P, 2019) |
"The effect of theophylline on cerebral blood flow (CBF), oxygen transport, and energy metabolism was investigated during and following brief episodes of asphyxia." | 3.69 | Cerebral blood flow and metabolism during repeated asphyxias in newborn piglets: influence of theophylline. ( Delivoria-Papadopoulos, M; Goplerud, JM, 1994) |
"The simultaneous determination of caffeine and theophylline plasmatic levels has been proposed when the later is used in the treatment of the newborn's apnea." | 3.68 | [Importance of monitoring theophylline and caffeine plasma levels in the management of neonatal apnea]. ( Sacristán del Castillo, JA; Soto Alvarez, J, 1991) |
" This view assumes that pharmacologic manipulation of apnea of prematurity is in itself a desirable goal and clearly superior to treatment of apneic episodes when they occur." | 3.66 | Adverse effects of caffeine and theophylline in the newborn infant. ( Aranda, JV; Clozel, M; Howell, J, 1981) |
"Those infants with asphyxial renal failure were followed up for 1 year." | 2.72 | Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial. ( Bhat, MA; Makhdoomi, MS; Mufti, MH; Shah, ZA, 2006) |
"Aminophylline has been shown to reduce severe renal dysfunction in neonates after perinatal asphyxia." | 1.62 | Aminophylline for renal protection in neonatal hypoxic-ischemic encephalopathy in the era of therapeutic hypothermia. ( Cho, SH; Chock, VY; Frymoyer, A, 2021) |
"Gestational age, gender, duration of treatment, body weight, and Apgar scores were not found to correlate significantly with theophylline clearance." | 1.27 | Factors influencing theophylline disposition in 179 newborns. ( Erkan, NV; Gal, P; Gilman, JT; Hersh, CB; Levine, RS, 1986) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (37.50) | 18.7374 |
1990's | 2 (8.33) | 18.2507 |
2000's | 4 (16.67) | 29.6817 |
2010's | 7 (29.17) | 24.3611 |
2020's | 2 (8.33) | 2.80 |
Authors | Studies |
---|---|
Bellos, I | 1 |
Pandita, A | 2 |
Yachha, M | 2 |
Chock, VY | 1 |
Cho, SH | 1 |
Frymoyer, A | 1 |
Bhatt, GC | 1 |
Gogia, P | 1 |
Bitzan, M | 1 |
Das, RR | 1 |
Aydin, M | 1 |
Hakan, N | 1 |
Zenciroglu, A | 1 |
Okumus, N | 1 |
Al-Wassia, H | 2 |
Raina, A | 1 |
Harish, R | 1 |
Jamwal, A | 1 |
Askenazi, D | 1 |
Eslami, Z | 1 |
Shajari, A | 1 |
Kheirandish, M | 1 |
Heidary, A | 1 |
Allende-Castro, C | 1 |
Espina-Marchant, P | 1 |
Bustamante, D | 1 |
Rojas-Mancilla, E | 1 |
Neira, T | 1 |
Gutierrez-Hernandez, MA | 1 |
Esmar, D | 1 |
Valdes, JL | 1 |
Morales, P | 1 |
Gebicke-Haerter, PJ | 1 |
Herrera-Marschitz, M | 1 |
Alshaikh, B | 1 |
Sauve, R | 1 |
Bakr, AF | 1 |
Bhat, MA | 1 |
Shah, ZA | 1 |
Makhdoomi, MS | 1 |
Mufti, MH | 1 |
Gal, P | 2 |
Boer, HR | 1 |
Toback, J | 1 |
Wells, TJ | 1 |
Erkan, NV | 2 |
Howell, J | 1 |
Clozel, M | 1 |
Aranda, JV | 1 |
Goplerud, JM | 1 |
Delivoria-Papadopoulos, M | 1 |
Jenik, AG | 1 |
Ceriani Cernadas, JM | 1 |
Gorenstein, A | 1 |
Ramirez, JA | 1 |
Vain, N | 1 |
Armadans, M | 1 |
Ferraris, JR | 1 |
Soto Alvarez, J | 1 |
Sacristán del Castillo, JA | 1 |
Closa, RM | 1 |
Tarres Roure, A | 1 |
Gómez Papi, A | 1 |
Casasin Edo, T | 1 |
Gilman, JT | 1 |
Levine, RS | 1 |
Hersh, CB | 1 |
Tervilä, L | 1 |
Vartiainen, E | 1 |
Kivalo, I | 1 |
Finnilä, MJ | 1 |
Väyrynen, M | 1 |
Nobel, J | 1 |
Meyburg, V | 1 |
Lupp, H | 1 |
Mengarda, G | 1 |
Mentzel, H | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Pharmacokinetics (PK) and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia[NCT05295784] | Phase 1 | 18 participants (Anticipated) | Interventional | 2024-06-30 | Not yet recruiting | ||
The Effect of Aminophylline on Preventing Acute Kidney Injury in Pediatric Patients Undergoing Open Heart Surgery[NCT03897335] | Phase 3 | 80 participants (Anticipated) | Interventional | 2019-02-07 | Recruiting | ||
[NCT02276170] | 9 participants (Actual) | Observational | 2014-10-31 | Terminated (stopped due to insufficient rate of accrual) | |||
Perioperative Aminophylline to Improve High Risk Renal Graft Outcome- a Double Blinded, Placebo Controlled, Randomized Clinical Trial[NCT01759862] | 50 participants (Actual) | Interventional | 2012-11-30 | Completed | |||
A Multicenter Randomized Controlled Trial of Therapeutic Hypothermia Plus Magnesium Sulphate (MgSO4) Versus Therapeutic Hypothermia Plus Placebo in the Management of Term and Near Term Babies With Hypoxic Ischemic Encephalopathy[NCT01646619] | Phase 3 | 300 participants (Anticipated) | Interventional | 2012-05-31 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
The investigators will measure blood creatinine on post-operative day 5 and using the Schwartz equation will calculate estimated glomerular filtration rate (GFR) to determine kidney function. (NCT01759862)
Timeframe: 5 days
Intervention | ml/min/1.73m2 (Mean) |
---|---|
Aminophylline | 67.39 |
Control | 80.48 |
The investigators will use the same cores that are obtained during routine 6 months protocol biopsies to quantify the amount of fibrosis (NCT01759862)
Timeframe: 6 months
Intervention | Participants (Count of Participants) |
---|---|
Aminophylline | 11 |
Control | 14 |
urinary NGAL(Neutrophil gelatinase-associated lipocalin) is a biomarker for kidney injury. NGAL levels 12h post-transplant were found to be a marker for development of delayed graft function and need for dialysis post-transplant. NGAL levels are corrected for urine creatinine. (NCT01759862)
Timeframe: 12 hours post transplant
Intervention | ng/mg (Median) |
---|---|
Aminophylline | 300.5 |
Control | 425.4 |
3 reviews available for theophylline and Asphyxia Neonatorum
Article | Year |
---|---|
Effectiveness of theophylline administration in neonates with perinatal asphyxia: a meta-analysis.
Topics: Acute Kidney Injury; Asphyxia; Asphyxia Neonatorum; Glomerular Filtration Rate; Humans; Infant, Newb | 2021 |
Theophylline and aminophylline for prevention of acute kidney injury in neonates and children: a systematic review.
Topics: Acute Kidney Injury; Aminophylline; Asphyxia Neonatorum; Bronchodilator Agents; Child; Child, Presch | 2019 |
Prophylactic theophylline for the prevention of severe renal dysfunction in term and post-term neonates with perinatal asphyxia: a systematic review and meta-analysis of randomized controlled trials.
Topics: Asphyxia Neonatorum; Glomerular Filtration Rate; Humans; Infant, Newborn; Infant, Postmature; Intens | 2013 |
5 trials available for theophylline and Asphyxia Neonatorum
Article | Year |
---|---|
Treating perinatal asphyxia with theophylline at birth helps to reduce the severity of renal dysfunction in term neonates.
Topics: Asphyxia Neonatorum; Humans; Infant, Newborn; Renal Insufficiency; Theophylline; Vasodilator Agents | 2016 |
Theophylline for prevention of kidney dysfunction in neonates with severe asphyxia.
Topics: Asphyxia Neonatorum; Cohort Studies; Creatinine; Female; Glomerular Filtration Rate; Humans; Infant, | 2009 |
Prophylactic theophylline to prevent renal dysfunction in newborns exposed to perinatal asphyxia--a study in a developing country.
Topics: Asphyxia Neonatorum; Chemoprevention; Developing Countries; Double-Blind Method; Humans; Infant, New | 2005 |
Prophylactic theophylline to prevent renal dysfunction in newborns exposed to perinatal asphyxia--a study in a developing country.
Topics: Asphyxia Neonatorum; Chemoprevention; Developing Countries; Double-Blind Method; Humans; Infant, New | 2005 |
Prophylactic theophylline to prevent renal dysfunction in newborns exposed to perinatal asphyxia--a study in a developing country.
Topics: Asphyxia Neonatorum; Chemoprevention; Developing Countries; Double-Blind Method; Humans; Infant, New | 2005 |
Prophylactic theophylline to prevent renal dysfunction in newborns exposed to perinatal asphyxia--a study in a developing country.
Topics: Asphyxia Neonatorum; Chemoprevention; Developing Countries; Double-Blind Method; Humans; Infant, New | 2005 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial.
Topics: Asphyxia Neonatorum; beta 2-Microglobulin; Body Weight; Creatinine; Glomerular Filtration Rate; Huma | 2006 |
A randomized, double-blind, placebo-controlled trial of the effects of prophylactic theophylline on renal function in term neonates with perinatal asphyxia.
Topics: Asphyxia Neonatorum; Double-Blind Method; Glomerular Filtration Rate; Humans; Infant, Newborn; Kidne | 2000 |
A randomized, double-blind, placebo-controlled trial of the effects of prophylactic theophylline on renal function in term neonates with perinatal asphyxia.
Topics: Asphyxia Neonatorum; Double-Blind Method; Glomerular Filtration Rate; Humans; Infant, Newborn; Kidne | 2000 |
A randomized, double-blind, placebo-controlled trial of the effects of prophylactic theophylline on renal function in term neonates with perinatal asphyxia.
Topics: Asphyxia Neonatorum; Double-Blind Method; Glomerular Filtration Rate; Humans; Infant, Newborn; Kidne | 2000 |
A randomized, double-blind, placebo-controlled trial of the effects of prophylactic theophylline on renal function in term neonates with perinatal asphyxia.
Topics: Asphyxia Neonatorum; Double-Blind Method; Glomerular Filtration Rate; Humans; Infant, Newborn; Kidne | 2000 |
A randomized, double-blind, placebo-controlled trial of the effects of prophylactic theophylline on renal function in term neonates with perinatal asphyxia.
Topics: Asphyxia Neonatorum; Double-Blind Method; Glomerular Filtration Rate; Humans; Infant, Newborn; Kidne | 2000 |
A randomized, double-blind, placebo-controlled trial of the effects of prophylactic theophylline on renal function in term neonates with perinatal asphyxia.
Topics: Asphyxia Neonatorum; Double-Blind Method; Glomerular Filtration Rate; Humans; Infant, Newborn; Kidne | 2000 |
A randomized, double-blind, placebo-controlled trial of the effects of prophylactic theophylline on renal function in term neonates with perinatal asphyxia.
Topics: Asphyxia Neonatorum; Double-Blind Method; Glomerular Filtration Rate; Humans; Infant, Newborn; Kidne | 2000 |
A randomized, double-blind, placebo-controlled trial of the effects of prophylactic theophylline on renal function in term neonates with perinatal asphyxia.
Topics: Asphyxia Neonatorum; Double-Blind Method; Glomerular Filtration Rate; Humans; Infant, Newborn; Kidne | 2000 |
A randomized, double-blind, placebo-controlled trial of the effects of prophylactic theophylline on renal function in term neonates with perinatal asphyxia.
Topics: Asphyxia Neonatorum; Double-Blind Method; Glomerular Filtration Rate; Humans; Infant, Newborn; Kidne | 2000 |
16 other studies available for theophylline and Asphyxia Neonatorum
Article | Year |
---|---|
Aminophylline for renal protection in neonatal hypoxic-ischemic encephalopathy in the era of therapeutic hypothermia.
Topics: Acute Kidney Injury; Aminophylline; Asphyxia Neonatorum; Biomarkers; Creatinine; Female; Humans; Hyp | 2021 |
Is the use of prophylactic theophylline safe for the prevention of severe renal dysfunction in term and post-term neonates with perinatal asphyxia?
Topics: Asphyxia Neonatorum; Humans; Infant, Postmature; Renal Insufficiency; Theophylline | 2014 |
Reply to: 'Is the use of prophylactic theophylline safe for the prevention of severe renal dysfunction in term and post-term neonates with perinatal asphyxia?'.
Topics: Asphyxia Neonatorum; Humans; Infant, Postmature; Renal Insufficiency; Theophylline | 2014 |
Should neonates with perinatal asphyxia receive a single dose of IV theophylline to prevent acute kidney injury?
Topics: Acute Kidney Injury; Asphyxia; Asphyxia Neonatorum; Female; Humans; Infant, Newborn; Pregnancy; Theo | 2016 |
Further studies on the hypothesis of PARP-1 inhibition as a strategy for lessening the long-term effects produced by perinatal asphyxia: effects of nicotinamide and theophylline on PARP-1 activity in brain and peripheral tissue : nicotinamide and theophyl
Topics: Animals; Animals, Newborn; Asphyxia; Asphyxia Neonatorum; Behavior, Animal; Brain; Heart; Humans; In | 2012 |
Effect of asphyxia on theophylline clearance in newborns.
Topics: Asphyxia Neonatorum; Humans; Infant, Newborn; Theophylline | 1982 |
Adverse effects of caffeine and theophylline in the newborn infant.
Topics: Apnea; Asphyxia Neonatorum; Caffeine; Cardiovascular System; Central Nervous System; Digestive Syste | 1981 |
Cerebral blood flow and metabolism during repeated asphyxias in newborn piglets: influence of theophylline.
Topics: Animals; Animals, Newborn; Asphyxia; Asphyxia Neonatorum; Brain; Cerebrovascular Circulation; Diseas | 1994 |
[Importance of monitoring theophylline and caffeine plasma levels in the management of neonatal apnea].
Topics: Apnea; Asphyxia Neonatorum; Caffeine; Humans; Infant, Newborn; Monitoring, Physiologic; Theophylline | 1991 |
[Monitoring theophylline in premature newborn infants].
Topics: Apnea; Asphyxia Neonatorum; Humans; Infant, Newborn; Infant, Premature, Diseases; Monitoring, Physio | 1989 |
Factors influencing theophylline disposition in 179 newborns.
Topics: Apgar Score; Asphyxia Neonatorum; Body Weight; Female; Gestational Age; Humans; Infant, Newborn; Inf | 1986 |
The effect of oxygen ventilation and vasodilator on uterine perfusion, fetal oxygen and acid-base balance. I. A study in abnormal gravidae.
Topics: Acid-Base Equilibrium; Anemia; Asphyxia Neonatorum; Erythroblastosis, Fetal; Female; Fetus; Humans; | 1973 |
[Prevention of fetal asphyxia with theophylline drugs].
Topics: Asphyxia Neonatorum; Electrocardiography; Female; Fetal Death; Fetal Diseases; Heart Rate; Humans; I | 1970 |
[Drug therapy of perinatal asphyxia].
Topics: Asphyxia Neonatorum; Atropine; Humans; Infant, Newborn; Injections, Intramuscular; Papaverine; Theop | 1971 |
[The association of theophylline, papaverine and methylatropine in the treatment of the idiopathic respiratory syndrome in premature infants].
Topics: Asphyxia Neonatorum; Atropine; Humans; Infant, Newborn; Infant, Premature, Diseases; Papaverine; Res | 1968 |
[Asphyxia neonatorum. II. Treatment with vasodilator and vagolytic agents].
Topics: Acidosis, Respiratory; Asphyxia Neonatorum; Atropine; Blood Circulation; Humans; Hypercapnia; Hypoxi | 1966 |