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theophylline and Arrhythmias, Cardiac

theophylline has been researched along with Arrhythmias, Cardiac in 80 studies

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

ExcerptRelevanceReference
"Theophylline and beta 2-mimetic agents have long been used concomitantly in the treatment of asthma, but divergent opinions are lingering on concerning the safety and effectiveness of this combination in both chronic and acute asthma."10.16[Combination of theophylline and beta-adrenergic agonists in the treatment of asthma: efficacy and tolerance. Review of the literature]. ( Iung, B; Laaban, JP; Rochemaure, J, 1989)
"The effect of intravenous theophylline upon the activity of creatinine kinase (CK) and its cardiac specific isoenzyme (CK-MB) and the frequency of cardiac arrhythmias were evaluated in 12 patients with bronchial asthma and spastic bronchitis."9.08Cardiac arrhythmias as a result of intravenous infusions of theophylline in patients with airway obstruction. ( Chazan, R; Droszcz, W; Karwat, K; Tadeusiak, W; Tyminska, K, 1995)
"We studied 15 nonsmoking, clinically stable asthmatic subjects aged 27 to 39 years to evaluate the potential cardiotoxic effects of combined use of a beta-adrenergic agonist drug and theophylline in the treatment of asthma."9.06Cardiac arrhythmias during the combined use of beta-adrenergic agonist drugs and theophylline. ( Barker, AF; Buist, AS; Coleman, JJ; Schultz, GE; Vollmer, WM, 1986)
"We compared the frequency and severity of cardiac arrhythmias during combined oral theophylline and inhaled salbutamol vs."9.06Theophylline and salbutamol in combination in patients with obstructive pulmonary disease and concurrent heart disease: effect on cardiac arrhythmias. ( Huikuri, H; Korhonen, UR; Linnaluoto, M; Poukkula, A, 1989)
"Enprofylline, a drug without adenosine antagonism and theophylline, a potent adenosine antagonist, were compared, double-blind, randomized, in acute asthma (n = 33)."9.06Comparison between theophylline and an adenosine non-blocking xanthine in acute asthma. ( Amundsen, T; Brenna, E; Eriksson, G; Holte, S; Källén, AG; Naustdal, T; Persson, CG; Storstein, L; Syvertsen, U; Vilsvik, JS, 1990)
"Bronchodilation and side effects of 28 days treatment with either a full therapeutic dose of theophylline slow-release preparation 500 mg twice daily (400-600 mg), a slow-release terbutaline preparation 10 mg twice daily or combinations of the 2 drugs in full or half doses were evaluated in 31 asthmatic outpatients in a double-blind, randomized crossover design."9.05Long-term oral therapy of asthma with terbutaline and theophylline, alone and combined. ( Gnosspelius, Y; Gymose, E; Laursen, LC; Taudorf, E; Weeke, B, 1985)
"The effect of intravenous theophylline upon the activity of creatinine kinase (CK) and its cardiac specific isoenzyme compound (CK-MB) and the frequency of cardiac arrhythmias was evaluated in 12 patients with bronchial asthma and spastic bronchitis."7.68[Effect of intravenous infusions of theophylline on cardiac arrhythmias and activity of creatinine kinase CK-MB in patients with airway obstruction]. ( Chazan, R; Droszcz, W; Eneser, M; Karwat, K; Tadeusiak, W; Tymińska, K, 1993)
"The authors determined the effect of acute and chronic aminophylline treatment on the arrhythmogenicity of epinephrine during halothane anesthesia."7.67Epinephrine arrhythmogenicity is enhanced by acute, but not chronic, aminophylline administration during halothane anesthesia in dogs. ( Gaba, DM; Maze, M; Nicholls, E; Prokocimer, PG, 1986)
"We monitored 14 asthmatic subjects (aged 18 to 60 years), with multiple 24-hour electrocardiogram (Holter) recordings, who were taking continuous sustained-release theophylline and beta-2-adrenergic therapy for control of their symptoms."7.67Lack of significant arrhythmogenicity from chronic theophylline and beta-2-adrenergic combination therapy in asthmatic subjects. ( Kelly, HW; Menendez, R; Voyles, W, 1985)
"The purpose of this study was to evaluate prospectively the occurrence of cardiac arrhythmias during the combined therapy with intravenous aminophylline and terbutaline in 29 consecutive patients with status asthmaticus."7.67Cardiac arrhythmias during the combined use of intravenous aminophylline and terbutaline in status asthmaticus. ( Chauvet, JP; Iung, B; Laaban, JP; Proteau, J; Psychoyos, I; Rochemaure, J, 1988)
"Cardiac arrhythmias often occur when patients receiving aminophylline are anesthetized with halothane."7.66Halothane-induced cardiac arrhythmias following administration of aminophylline in experimental animals. ( Berger, JM; Ricker, SM; Roe, SD; Stirt, JA; Sullivan, SF, 1981)
"Long-term ambulatory Holter-monitoring was used to evaluate the arrhythmogenic effects of beta 2-agonist therapy, alone and in combination with a xanthine derivative, theophylline or enprofylline."6.66Cardiac arrhythmias in patients with mild-to-moderate obstructive lung disease. Comparison of beta-agonist therapy alone and in combination with a xanthine derivative, enprofylline or theophylline. ( Conradson, TB; Eklundh, G; Olofsson, B; Pahlm, O; Persson, G, 1985)
"Theophylline and beta 2-mimetic agents have long been used concomitantly in the treatment of asthma, but divergent opinions are lingering on concerning the safety and effectiveness of this combination in both chronic and acute asthma."6.16[Combination of theophylline and beta-adrenergic agonists in the treatment of asthma: efficacy and tolerance. Review of the literature]. ( Iung, B; Laaban, JP; Rochemaure, J, 1989)
"A progression from encephalopathy to seizures was observed following aminophylline administration."5.26Caffeine- and aminophylline-induced seizures. ( Chu, NS, 1981)
"The effect of intravenous theophylline upon the activity of creatinine kinase (CK) and its cardiac specific isoenzyme (CK-MB) and the frequency of cardiac arrhythmias were evaluated in 12 patients with bronchial asthma and spastic bronchitis."5.08Cardiac arrhythmias as a result of intravenous infusions of theophylline in patients with airway obstruction. ( Chazan, R; Droszcz, W; Karwat, K; Tadeusiak, W; Tyminska, K, 1995)
"We studied 15 nonsmoking, clinically stable asthmatic subjects aged 27 to 39 years to evaluate the potential cardiotoxic effects of combined use of a beta-adrenergic agonist drug and theophylline in the treatment of asthma."5.06Cardiac arrhythmias during the combined use of beta-adrenergic agonist drugs and theophylline. ( Barker, AF; Buist, AS; Coleman, JJ; Schultz, GE; Vollmer, WM, 1986)
"We compared the frequency and severity of cardiac arrhythmias during combined oral theophylline and inhaled salbutamol vs."5.06Theophylline and salbutamol in combination in patients with obstructive pulmonary disease and concurrent heart disease: effect on cardiac arrhythmias. ( Huikuri, H; Korhonen, UR; Linnaluoto, M; Poukkula, A, 1989)
"Enprofylline, a drug without adenosine antagonism and theophylline, a potent adenosine antagonist, were compared, double-blind, randomized, in acute asthma (n = 33)."5.06Comparison between theophylline and an adenosine non-blocking xanthine in acute asthma. ( Amundsen, T; Brenna, E; Eriksson, G; Holte, S; Källén, AG; Naustdal, T; Persson, CG; Storstein, L; Syvertsen, U; Vilsvik, JS, 1990)
"Bronchodilation and side effects of 28 days treatment with either a full therapeutic dose of theophylline slow-release preparation 500 mg twice daily (400-600 mg), a slow-release terbutaline preparation 10 mg twice daily or combinations of the 2 drugs in full or half doses were evaluated in 31 asthmatic outpatients in a double-blind, randomized crossover design."5.05Long-term oral therapy of asthma with terbutaline and theophylline, alone and combined. ( Gnosspelius, Y; Gymose, E; Laursen, LC; Taudorf, E; Weeke, B, 1985)
"The therapeutic strategy is much the same as for younger asthmatics but certain aspects take on greater importance: concerns about osteoporosis with long-term corticosteroid therapy (both oral and inhaled), the risk of arrhythmias with beta-2 adrenergic drugs and the significant side-effects of theophylline justifies, in difficult cases, consideration of anti-cholinergic and/or anti-leukotriene therapy."4.82[Asthma in the elderly]. ( Radenne, F; Tonnel, AB; Verkindre, C, 2003)
"Moricizine is well absorbed after oral administration and undergoes extensive first-pass metabolism."3.76Clinical pharmacokinetics of moricizine. ( Barbey, JT; Schwartz, SL; Siddoway, LA; Woosley, RL, 1990)
"Despite the declining use of theophylline, episodes of intoxication continue to occur, producing seizures, arrhythmias, and death."3.70Life-threatening events after theophylline overdose: a 10-year prospective analysis. ( Shannon, M, 1999)
"To identify risk factors for the development of seizures and cardiac arrhythmias after chronic, unintentional theophylline intoxication we monitored the clinical course of 72 consecutive patients referred to a regional poison center with chronic theophylline intoxication (serum theophylline concentration, greater than or equal to 167 mumol/L after protracted use)."3.68The influence of age vs peak serum concentration on life-threatening events after chronic theophylline intoxication. ( Lovejoy, FH; Shannon, M, 1990)
"The effect of intravenous theophylline upon the activity of creatinine kinase (CK) and its cardiac specific isoenzyme compound (CK-MB) and the frequency of cardiac arrhythmias was evaluated in 12 patients with bronchial asthma and spastic bronchitis."3.68[Effect of intravenous infusions of theophylline on cardiac arrhythmias and activity of creatinine kinase CK-MB in patients with airway obstruction]. ( Chazan, R; Droszcz, W; Eneser, M; Karwat, K; Tadeusiak, W; Tymińska, K, 1993)
"We assessed the effects of the adenosine antagonist 8-(p-sulfophenyl)theophylline (SPT) and adenosine on myocardial infarct size and the incidence of ventricular arrhythmias in five groups of rats: control (nonpreconditioned)+vehicle, control+SPT, preconditioned+vehicle, preconditioned+SPT, and control (nonpreconditioned)+adenosine."3.68The cardioprotective effects of ischemic 'preconditioning' are not mediated by adenosine receptors in rat hearts. ( Kloner, RA; Li, Y, 1993)
"Theophylline causes tachycardia and serious arrhythmias even at STC considered to be therapeutic."3.68The arrhythmogenicity of theophylline. A multivariate analysis of clinical determinants. ( Bittar, G; Friedman, HS, 1991)
"We monitored 14 asthmatic subjects (aged 18 to 60 years), with multiple 24-hour electrocardiogram (Holter) recordings, who were taking continuous sustained-release theophylline and beta-2-adrenergic therapy for control of their symptoms."3.67Lack of significant arrhythmogenicity from chronic theophylline and beta-2-adrenergic combination therapy in asthmatic subjects. ( Kelly, HW; Menendez, R; Voyles, W, 1985)
"3 mM theophylline decreased the time to onset of arrhythmias produced by 5 microM digoxin and the fractional occupancy of specific binding sites on Na,K-adenosine triphosphatase by digoxin at the onset of these dysrhythmic events."3.67Effects of theophylline on inotropic and arrhythmogenic actions of cardiotonic steroids in guinea pig cardiac muscle. ( Kafiluddi, R; Kennedy, RH; Seifen, E, 1988)
"The purpose of this study was to evaluate prospectively the occurrence of cardiac arrhythmias during the combined therapy with intravenous aminophylline and terbutaline in 29 consecutive patients with status asthmaticus."3.67Cardiac arrhythmias during the combined use of intravenous aminophylline and terbutaline in status asthmaticus. ( Chauvet, JP; Iung, B; Laaban, JP; Proteau, J; Psychoyos, I; Rochemaure, J, 1988)
"The authors determined the effect of acute and chronic aminophylline treatment on the arrhythmogenicity of epinephrine during halothane anesthesia."3.67Epinephrine arrhythmogenicity is enhanced by acute, but not chronic, aminophylline administration during halothane anesthesia in dogs. ( Gaba, DM; Maze, M; Nicholls, E; Prokocimer, PG, 1986)
"The frequency and type of dysrhythmias observed in asthmatic patients treated with epinephrine alone, and those given epinephrine and intravenous aminophylline, were compared."3.66Cardiac dysrhythmias during the treatment of acute asthma. A comparison of two treatment regimens by a double blind protocol. ( Gibson, G; Josephson, GW; Kennedy, HL; MacKenzie, EJ, 1980)
"Cardiac arrhythmias often occur when patients receiving aminophylline are anesthetized with halothane."3.66Halothane-induced cardiac arrhythmias following administration of aminophylline in experimental animals. ( Berger, JM; Ricker, SM; Roe, SD; Stirt, JA; Sullivan, SF, 1981)
"Allergy and/or contraindications for theophylline and adrenergic drugs can be a life-threatening problem for patients with respiratory failure resulting from status asthmaticus."3.66Pulmonary lavage in a patient in status asthmaticus receiving mechanical ventilation: a case report. ( Maxson, TR; Shridharani, M, 1982)
"Long-term ambulatory Holter-monitoring was used to evaluate the arrhythmogenic effects of beta 2-agonist therapy, alone and in combination with a xanthine derivative, theophylline or enprofylline."2.66Cardiac arrhythmias in patients with mild-to-moderate obstructive lung disease. Comparison of beta-agonist therapy alone and in combination with a xanthine derivative, enprofylline or theophylline. ( Conradson, TB; Eklundh, G; Olofsson, B; Pahlm, O; Persson, G, 1985)
"The type of arrhythmias found may be supraventricular (premature atrial beats, paroxysmal supraventricular tachycardia, multifocal atrial tachycardia, atrial flutter, atrial fibrillation) or ventricular (premature ventricular beats, sustained ventricular tachycardia, torsades de pointes, ventricular fibrillation) that may lead to sudden cardiac death."2.40[Evaluation of hyperkinetic cardiac arrhythmia in chronic obstructive bronchopneumopathy]. ( Conte, G; Lauro, S; Lazzarin, M; Perrone, A; Rigon, N, 1997)
"Toxic-range STCs are relatively common in the ED population, occur primarily as a result of patient and physician dosing errors, and cause a broad range of toxic manifestations of varying severity."2.38Theophylline toxicity: clinical features of 116 consecutive cases. ( Sessler, CN, 1990)
"Ventricular fibrillation is a major mechanism of sudden death."2.36Catecholamine-mediated arrhythmias in acute myocardial infarction. Experimental evidence and role of beta-adrenoceptor blockade. ( Lubbe, WF; Opie, LH, 1979)
"for 10 min)-induced hypotension, arrhythmias, and sudden death."1.29Reversal of acute theophylline toxicity by calcium channel blockers in dogs and rats. ( Alleva, FR; Balazs, T; Joseph, X; Vick, JA; Whitehurst, VE; Zhang, J, 1996)
"Mixed atrial and ventricular arrhythmias, which are rarely mentioned as a specific feature of theophylline intoxication, were found in 16% of our patients and accounted for 29% of the cardiovascular manifestations."1.29The clinical implication of theophylline intoxication in the Emergency Department. ( Chern, TL; Deng, JF; Hu, SC; Lee, CH; Tsai, J; Wang, RB, 1994)
"Although life-threatening events (seizures or arrhythmias) occurred at a similar rate across categories, the (theo) at which these events occurred was significantly higher in patients with acute intoxication than in those with chronic intoxication (100 vs 42 micrograms/ml; p = 0."1.28Effect of acute versus chronic intoxication on clinical features of theophylline poisoning in children. ( Lovejoy, FH; Shannon, M, 1992)
"Eight patients had grand mal seizures and six developed arrhythmias (ventricular fibrillation, 3; atrial fibrillation, 2; supraventricular tachycardia, 1)."1.28Management of theophylline overdose patients in the intensive care unit. ( Henderson, A; Pond, SM; Wright, DM, 1992)
"The predicted steady-state serum theophylline concentration was calculated from the dosage rate divided by the predicted clearance to determine how many elevated concentrations (greater than 20 mg/L) were predictable."1.28A prospective evaluation of elevated serum theophylline concentrations to determine if high concentrations are predictable. ( Cranberg, JA; Ganz, MA; Greenberger, PA; Hubler, GL, 1991)
"Four seizures occurred in patients with prior seizures, while two had new onset seizures with levels of 27 and 30 micrograms/mL."1.28Risk of toxicity in patients with elevated theophylline levels. ( Connors, AF; Devlin, C; Emerman, CL, 1990)
"Ventricular extrasystoles were detectable in all patients with greater than 30/h occurring in 13."1.27[Ventricular arrhythmias in cor pulmonale. The effect of oxygen treatment]. ( Barmeyer, J; Lawo, T; Machraoui, A; Martin, W; Schött, D; Ulmer, WT, 1986)
" Whereas aminophylline in therapeutic dosage failed to provoke VE in arrhythmia-free COPD patients, the effect of aminophylline on pre-existent VE is variable."1.27The effect of aminophylline on cardiac rhythm in advanced chronic obstructive pulmonary disease: correlation with serum theophylline levels. ( Au, WY; de Soyza, ND; Dutt, AK; Hargis, JL; Tuck, RL, 1983)
"The slow disappearance of the arrhythmia is a result of the prolonged half-life of theophylline in the fetus."1.27[Fetal bigeminus following combined bronchodilator treatment of the mother]. ( Neeb, U, 1986)
" No relationship between the serum concentrations and the severity of toxic effect was seen."1.27Reassessment of theophylline toxicity. Serum concentrations, clinical course, and treatment. ( Bertino, JS; Walker, JW, 1987)
"Although arrhythmias associated with myocardial infarction are managed primarily with drug therapy, those associated with acute respiratory failure respond best to adequate oxygenation and correction of metabolic and hemodynamic abnormalities."1.27Managing asthma and COPD in patients with cardiovascular disease. ( George, RB; Payne, DK, 1985)
" But the danger of rhythm disturbances often can be reduced by cutting the dosage or choosing a preparation with more beta 2 activity."1.26When drug therapy for lung disease affects the heart. ( Webb-Johnson, DC, 1976)
" Maintenance dosing adjustments are then based on serum determinations and the presence of toxic effects."1.26Theophylline toxicity after the use of aminophylline in the treatment of cerebral vasospasm. ( Bailey, RT; Blouin, RA; Rapp, RP; Young, B, 1981)
"A progression from encephalopathy to seizures was observed following aminophylline administration."1.26Caffeine- and aminophylline-induced seizures. ( Chu, NS, 1981)
"Three of six dogs in part 1 had arrhythmias following aminophylline, with serum theophylline levels ranging from 48 to 66 mg/L."1.26Arrhythmogenic effects of aminophylline during halothane anesthesia in experimental animals. ( Berger, JM; Ricker, SM; Stirt, JA; Sullivan, SF, 1980)

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-199052 (65.00)18.7374
1990's23 (28.75)18.2507
2000's4 (5.00)29.6817
2010's1 (1.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Antzelevitch, C1
Viskin, S1
Radenne, F1
Verkindre, C1
Tonnel, AB1
Aviado, DM1
Folle, LE1
Pisanty, J1
Opie, LH3
Muller, C1
Nathan, D2
Daries, P1
Lubbe, WF4
Stirt, JA3
Sullivan, SF3
Nguyen, T1
West, EJ1
Boldy, DA1
Buckley, BM1
Vale, JA1
Andersen, E1
Jakobsen, S1
Jørgensen, C1
Damgaard-Iversen, B1
Gaudreault, P1
Wason, S1
Lovejoy, FH3
Dutt, AK1
de Soyza, ND1
Au, WY1
Hargis, JL1
Tuck, RL1
Shridharani, M1
Maxson, TR1
Taylor, AT1
Berger, JM2
Ricker, SM2
Roe, SD1
Bailey, RT1
Young, B1
Rapp, RP1
Blouin, RA1
Jackowska, M1
Matthay, RA1
Depew, CC1
Josephson, GW1
Kennedy, HL1
MacKenzie, EJ1
Gibson, G1
Chu, NS1
Cukier, A1
Vargas, FS1
Teixeira, LR1
Grupi, CJ1
Terra-Filho, M1
Carvalho-Pinto, RM1
Light, RW1
Chazan, R2
Karwat, K2
Tyminska, K2
Tadeusiak, W2
Droszcz, W2
Vegh, A1
Papp, JG1
Parratt, JR1
Tsai, J1
Chern, TL1
Hu, SC1
Lee, CH1
Wang, RB1
Deng, JF1
Eneser, M1
Shannon, M4
Li, Y1
Kloner, RA1
Whitehurst, VE1
Joseph, X1
Vick, JA1
Alleva, FR1
Zhang, J1
Balazs, T1
Goggins, M1
Conte, G1
Lauro, S1
Lazzarin, M1
Rigon, N1
Perrone, A1
Grund, F1
Sommerschild, HT1
Lyberg, T1
Kirkeboen, KA1
Ilebekk, A1
Dini, FL1
Cogo, R1
McGuigan, ME1
Colbridge, M1
Webb-Johnson, DC1
Loughnan, PM1
Mc Namara, JM1
Shim, CS1
Scher, SM1
Williams, MH1
Henderson, A1
Wright, DM1
Pond, SM1
Greenberger, PA1
Cranberg, JA1
Ganz, MA1
Hubler, GL1
Bender, PR1
Brent, J1
Kulig, K1
Bittar, G1
Friedman, HS1
Sessler, CN2
Vilsvik, JS1
Persson, CG1
Amundsen, T1
Brenna, E1
Naustdal, T1
Syvertsen, U1
Storstein, L1
Källén, AG1
Eriksson, G1
Holte, S1
Emerman, CL1
Devlin, C1
Connors, AF1
Cohen, MD1
Siddoway, LA1
Schwartz, SL1
Barbey, JT1
Woosley, RL1
Escamilla, R1
Longhi, R1
Miguères, J1
Jover, A1
Krempf, M1
Massabuau, P1
Bonhoure, JP1
Machraoui, A1
Schött, D1
Martin, W1
Lawo, T1
Barmeyer, J1
Ulmer, WT1
Lin, CI1
Chuang, IN1
Cheng, KK1
Chiang, BN1
Holbrook, M1
Coker, SJ1
Iung, B2
Laaban, JP2
Rochemaure, J2
Laursen, LC1
Taudorf, E1
Gnosspelius, Y1
Gymose, E1
Weeke, B1
Poukkula, A1
Korhonen, UR1
Huikuri, H1
Linnaluoto, M1
Kolander, SA1
Nydegger, CC1
Porter, RS1
Kafiluddi, R1
Kennedy, RH1
Seifen, E1
Kelly, HW1
Menendez, R1
Voyles, W1
Conradson, TB1
Eklundh, G1
Olofsson, B1
Pahlm, O1
Persson, G1
Coleman, JJ1
Vollmer, WM1
Barker, AF1
Schultz, GE1
Buist, AS1
Kessler, KM1
Interian, A1
Cox, M1
Topaz, O1
De Marchena, EJ1
Myerburg, RJ1
Chauvet, JP1
Psychoyos, I1
Proteau, J1
Eckstein, M1
Cegła, M1
Claussen, D1
Schlensog, I1
Winkler, H1
Prokocimer, PG1
Nicholls, E1
Gaba, DM1
Maze, M1
Neeb, U1
Aitken, ML1
Martin, TR1
Zanić-Matanić, D1
Bertino, JS1
Walker, JW1
George, RB1
Payne, DK1
Rietveld, AP1
Diderich, PP1
Saxena, PR1
Bhargava, KP1
Smolarz, W1
Kośmider, S1
John, P1
Berg, D1
Hammacher, K1
Gärtner, K1
Bonath, K1
Gruner, W1
Wernicke, K1
Schulz, J1
Schuler, R1
Meschino, S1
Meoni, S1
Massari, F1
Fontana, F1
Emig, W1
Buisson, P1
Bonerandi, JJ1

Reviews

12 reviews available for theophylline and Arrhythmias, Cardiac

ArticleYear
[Asthma in the elderly].
    Revue des maladies respiratoires, 2003, Volume: 20, Issue:1 Pt 1

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonist

2003
Aminophylline.
    Anesthesia and analgesia, 1981, Volume: 60, Issue:8

    Topics: Adult; Aminophylline; Anesthesia; Animals; Anticonvulsants; Arrhythmias, Cardiac; Asthma; Biotransfo

1981
Advances in the treatment of poisoning I.
    Journal of clinical and hospital pharmacy, 1984, Volume: 9, Issue:3

    Topics: Arrhythmias, Cardiac; Cardiac Glycosides; Digitalis Glycosides; Hemoperfusion; Humans; Hypokalemia;

1984
[Evaluation of hyperkinetic cardiac arrhythmia in chronic obstructive bronchopneumopathy].
    Minerva cardioangiologica, 1997, Volume: 45, Issue:9

    Topics: Adrenergic beta-Agonists; Arrhythmias, Cardiac; Bronchodilator Agents; Bronchopneumonia; Digitalis G

1997
Doxofylline: a new generation xanthine bronchodilator devoid of major cardiovascular adverse effects.
    Current medical research and opinion, 2001, Volume: 16, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Asthma; Bronchodilator Agents; Cardiovascular Diseases; Drug Evaluati

2001
Poisoning potpourri.
    Pediatrics in review, 2001, Volume: 22, Issue:9

    Topics: Acetaminophen; Age Factors; Alcohol Drinking; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac

2001
Theophylline overdose: clinical features and management.
    Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association, 2001, Volume: 8, Issue:9

    Topics: Adult; Arrhythmias, Cardiac; Bronchodilator Agents; Charcoal; Child; Drug Overdose; Emergency Nursin

2001
Biochemical aspects of arrhythmogenesis and ventricular fibrillation.
    The American journal of cardiology, 1979, Volume: 43, Issue:1

    Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardia

1979
Catecholamine-mediated arrhythmias in acute myocardial infarction. Experimental evidence and role of beta-adrenoceptor blockade.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Nov-24, Volume: 56, Issue:22

    Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Catecholamines; Cats; Coronary Disease;

1979
Theophylline toxicity: clinical features of 116 consecutive cases.
    The American journal of medicine, 1990, Volume: 88, Issue:6

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Charcoal; Chromatography, High Pressure Liquid; Drug Overdo

1990
Clinical pharmacokinetics of moricizine.
    The American journal of cardiology, 1990, Feb-20, Volume: 65, Issue:8

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cimetidine; Clinical Trials as Topic; Digoxin; Drug In

1990
[Combination of theophylline and beta-adrenergic agonists in the treatment of asthma: efficacy and tolerance. Review of the literature].
    Revue de pneumologie clinique, 1989, Volume: 45, Issue:4

    Topics: Acute Disease; Adrenergic beta-Agonists; Arrhythmias, Cardiac; Asthma; Bronchi; Drug Therapy, Combin

1989

Trials

9 trials available for theophylline and Arrhythmias, Cardiac

ArticleYear
Arrhythmogenic effects of combined orally administered theophylline and albuterol in patients with chronic obstructive pulmonary disease.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1994, Volume: 27, Issue:12

    Topics: Administration, Oral; Aged; Albuterol; Arrhythmias, Cardiac; Bronchodilator Agents; Drug Therapy, Co

1994
Cardiac arrhythmias as a result of intravenous infusions of theophylline in patients with airway obstruction.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:3

    Topics: Adult; Aged; Airway Obstruction; Arrhythmias, Cardiac; Creatine Kinase; Electrocardiography, Ambulat

1995
Comparison between theophylline and an adenosine non-blocking xanthine in acute asthma.
    The European respiratory journal, 1990, Volume: 3, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Asthma; Bronchodilator Agents; Double-

1990
Clinical pharmacokinetics of moricizine.
    The American journal of cardiology, 1990, Feb-20, Volume: 65, Issue:8

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cimetidine; Clinical Trials as Topic; Digoxin; Drug In

1990
[Combination of theophylline and beta-adrenergic agonists in the treatment of asthma: efficacy and tolerance. Review of the literature].
    Revue de pneumologie clinique, 1989, Volume: 45, Issue:4

    Topics: Acute Disease; Adrenergic beta-Agonists; Arrhythmias, Cardiac; Asthma; Bronchi; Drug Therapy, Combin

1989
Long-term oral therapy of asthma with terbutaline and theophylline, alone and combined.
    European journal of respiratory diseases, 1985, Volume: 66, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Akathisia, Drug-Induced; Arrhythmias, Cardiac; Asthma

1985
Theophylline and salbutamol in combination in patients with obstructive pulmonary disease and concurrent heart disease: effect on cardiac arrhythmias.
    Journal of internal medicine, 1989, Volume: 226, Issue:4

    Topics: Aged; Albuterol; Arrhythmias, Cardiac; Clinical Trials as Topic; Delayed-Action Preparations; Drug T

1989
Cardiac arrhythmias in patients with mild-to-moderate obstructive lung disease. Comparison of beta-agonist therapy alone and in combination with a xanthine derivative, enprofylline or theophylline.
    Chest, 1985, Volume: 88, Issue:4

    Topics: Adrenergic beta-Agonists; Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind

1985
Cardiac arrhythmias during the combined use of beta-adrenergic agonist drugs and theophylline.
    Chest, 1986, Volume: 90, Issue:1

    Topics: Adrenergic beta-Agonists; Adult; Arrhythmias, Cardiac; Asthma; Clinical Trials as Topic; Drug Therap

1986

Other Studies

61 other studies available for theophylline and Arrhythmias, Cardiac

ArticleYear
Should theophylline be added to the J wave syndrome therapeutic armamentarium?
    Pacing and clinical electrophysiology : PACE, 2018, Volume: 41, Issue:5

    Topics: Arrhythmias, Cardiac; Electrocardiography; Humans; Syndrome; Theophylline

2018
The cardiopulmonary effects of a quinazoline (MJ 1988): cardiac stimulant, pulmonary vasodilator and bronchodilator.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:1

    Topics: Aminophylline; Animals; Arrhythmias, Cardiac; Blood Flow Velocity; Bronchi; Dogs; Heart; Muscle Cont

1967
Evidence for role of cyclic AMP as second messenger of arrhythmogenic effects of beta-stimulation.
    Advances in cyclic nucleotide research, 1980, Volume: 12

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Bucladesine; Coronary Disease; Cyclic AMP; Disease

1980
Modulation of myocardial cyclic AMP and vulnerability to fibrillation in the rat heart.
    Federation proceedings, 1983, May-15, Volume: 42, Issue:8

    Topics: Adenosine; Animals; Arrhythmias, Cardiac; Coronary Vessels; Cyclic AMP; Heart; Ligation; Myocardium;

1983
[Theophylline poisoning with particular attention to cardiac complications].
    Ugeskrift for laeger, 1984, Jun-04, Volume: 146, Issue:23

    Topics: Aged; Arrhythmias, Cardiac; Female; Heart Diseases; Humans; Male; Middle Aged; Theophylline

1984
Acute pediatric theophylline overdose: a summary of 28 cases.
    The Journal of pediatrics, 1983, Volume: 102, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Arrhythmias, Cardiac; Child; Child, Preschool; Female; Humans; Inf

1983
The effect of aminophylline on cardiac rhythm in advanced chronic obstructive pulmonary disease: correlation with serum theophylline levels.
    European journal of respiratory diseases, 1983, Volume: 64, Issue:4

    Topics: Aged; Aminophylline; Arrhythmias, Cardiac; Heart Rate; Heart Ventricles; Humans; Lung Diseases, Obst

1983
Pulmonary lavage in a patient in status asthmaticus receiving mechanical ventilation: a case report.
    Annals of allergy, 1982, Volume: 49, Issue:3

    Topics: Aminophylline; Arrhythmias, Cardiac; Asthma; Female; Humans; Lung; Middle Aged; Respiration, Artific

1982
A difficult monitoring situation: theophylline toxicity.
    Drug intelligence & clinical pharmacy, 1982, Volume: 16, Issue:11

    Topics: Aged; Aminophylline; Arrhythmias, Cardiac; Female; Humans; Theophylline

1982
Arrhythmogenic effects of aminophylline during halothane anesthesia in experimental animals.
    Anesthesia and analgesia, 1980, Volume: 59, Issue:6

    Topics: Aminophylline; Animals; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressure; Dogs; Dose-Respons

1980
Halothane-induced cardiac arrhythmias following administration of aminophylline in experimental animals.
    Anesthesia and analgesia, 1981, Volume: 60, Issue:7

    Topics: Aminophylline; Animals; Arrhythmias, Cardiac; Dogs; Dose-Response Relationship, Drug; Drug Interacti

1981
Theophylline toxicity after the use of aminophylline in the treatment of cerebral vasospasm.
    Neurosurgery, 1981, Volume: 9, Issue:6

    Topics: Aminophylline; Arrhythmias, Cardiac; Drug Therapy, Combination; Female; Humans; Infusions, Parentera

1981
[Pharmacodynamic properties of the optical isomers of 2-N(theophyllinyl-7 1-acetyl)aminobutanol and their chloro derivatives].
    Annales Academiae Medicae Stetinensis, 1981, Volume: 27

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Evaluation, Preclinical; Electrocardiogr

1981
Obstructive airway disease: rational therapy with theophylline agents.
    Geriatrics, 1980, Volume: 35, Issue:2

    Topics: Administration, Oral; Aged; Airway Obstruction; Arrhythmias, Cardiac; Asthma; Biotransformation; Fem

1980
Cardiac dysrhythmias during the treatment of acute asthma. A comparison of two treatment regimens by a double blind protocol.
    Chest, 1980, Volume: 78, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aminophylline; Arrhythmias, Cardiac; Asthma; Double-Blind Method;

1980
Caffeine- and aminophylline-induced seizures.
    Epilepsia, 1981, Volume: 22, Issue:1

    Topics: Aminophylline; Animals; Arrhythmias, Cardiac; Caffeine; Cerebral Cortex; Electrocardiography; Electr

1981
Pronounced antiarrhythmic effects of preconditioning in anaesthetized dogs: is adenosine involved?
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:1

    Topics: Adenosine; Anesthesia, General; Animals; Arrhythmias, Cardiac; Blood Flow Velocity; Blood Pressure;

1995
The clinical implication of theophylline intoxication in the Emergency Department.
    Human & experimental toxicology, 1994, Volume: 13, Issue:10

    Topics: Aged; Analysis of Variance; Arrhythmias, Cardiac; Asthma; Creatine Kinase; Digestive System; Dose-Re

1994
[Effect of intravenous infusions of theophylline on cardiac arrhythmias and activity of creatinine kinase CK-MB in patients with airway obstruction].
    Polskie Archiwum Medycyny Wewnetrznej, 1993, Volume: 90, Issue:6

    Topics: Adult; Aged; Airway Obstruction; Arrhythmias, Cardiac; Asthma; Bronchitis; Creatine Kinase; Female;

1993
Predictors of major toxicity after theophylline overdose.
    Annals of internal medicine, 1993, Dec-15, Volume: 119, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Arrhythmias, Cardiac; Chronic Disease; Drug Overdose;

1993
The cardioprotective effects of ischemic 'preconditioning' are not mediated by adenosine receptors in rat hearts.
    Circulation, 1993, Volume: 87, Issue:5

    Topics: Adenosine; Animals; Arrhythmias, Cardiac; Female; Heart; Hemodynamics; Myocardial Ischemia; Myocardi

1993
Reversal of acute theophylline toxicity by calcium channel blockers in dogs and rats.
    Toxicology, 1996, Jun-17, Volume: 110, Issue:1-3

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Bronchodilator Agents; Calcium; Calcium Channel Block

1996
Theophylline and sleep-disordered breathing in heart failure.
    The New England journal of medicine, 1997, Jan-30, Volume: 336, Issue:5

    Topics: Arrhythmias, Cardiac; Heart Failure; Humans; Sleep Apnea Syndromes; Theophylline

1997
Life-threatening events after theophylline overdose: a 10-year prospective analysis.
    Archives of internal medicine, 1999, May-10, Volume: 159, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Bronchodilator Agents; Chronic Disease

1999
Microembolization in pigs: effects on coronary blood flow and myocardial ischemic tolerance.
    The American journal of physiology, 1999, Volume: 277, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Embolism; Female; Ischemic Pr

1999
When drug therapy for lung disease affects the heart.
    Geriatrics, 1976, Volume: 31, Issue:11

    Topics: Adolescent; Adult; Aerosol Propellants; Aged; Arrhythmias, Cardiac; Bronchodilator Agents; Catechola

1976
Paroxysmal supraventricular tachycardia during theophylline therapy in a premature infant.
    The Journal of pediatrics, 1978, Volume: 92, Issue:6

    Topics: Arrhythmias, Cardiac; Half-Life; Heart Ventricles; Humans; Infant, Newborn; Infant, Premature, Disea

1978
Effect of bronchodilator agents on arrhythmia.
    New York state journal of medicine, 1976, Volume: 76, Issue:12

    Topics: Arrhythmias, Cardiac; Bronchodilator Agents; Humans; Isoproterenol; Lung Diseases, Obstructive; Theo

1976
Management of theophylline overdose patients in the intensive care unit.
    Anaesthesia and intensive care, 1992, Volume: 20, Issue:1

    Topics: Absorption; Adolescent; Adult; Arrhythmias, Cardiac; Charcoal; Critical Care; Drug Overdose; Female;

1992
Effect of acute versus chronic intoxication on clinical features of theophylline poisoning in children.
    The Journal of pediatrics, 1992, Volume: 121, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Arrhythmias, Cardiac; Bicarbonates; Child; Child, Pre

1992
A prospective evaluation of elevated serum theophylline concentrations to determine if high concentrations are predictable.
    The American journal of medicine, 1991, Volume: 91, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Body Weight; Humans; Lung Diseases, Obstructiv

1991
Cardiac arrhythmias during theophylline toxicity.
    Chest, 1991, Volume: 100, Issue:3

    Topics: Adult; Aged; Arrhythmias, Cardiac; Humans; Middle Aged; Theophylline

1991
The arrhythmogenicity of theophylline. A multivariate analysis of clinical determinants.
    Chest, 1991, Volume: 99, Issue:6

    Topics: Aged; Arrhythmias, Cardiac; Asthma; Cross-Sectional Studies; Electrocardiography; Female; Heart Rate

1991
The influence of age vs peak serum concentration on life-threatening events after chronic theophylline intoxication.
    Archives of internal medicine, 1990, Volume: 150, Issue:10

    Topics: Age Factors; Arrhythmias, Cardiac; Boston; Chronic Disease; Humans; Longitudinal Studies; Middle Age

1990
Risk of toxicity in patients with elevated theophylline levels.
    Annals of emergency medicine, 1990, Volume: 19, Issue:6

    Topics: Aged; Arrhythmias, Cardiac; Causality; Female; Heart Failure; Humans; Hypotension; Intensive Care Un

1990
Cardiac arrhythmias during theophylline toxicity. A prospective continuous electrocardiographic study.
    Chest, 1990, Volume: 98, Issue:3

    Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Electrocardiography, Ambulatory; Female; Heart Dis

1990
[Cardiac tolerance of a beta-2-sympathomimetic spray: fenoterol. Apropos of 37 patients followed using a Holter monitor during a brief treatment protocol].
    Revue des maladies respiratoires, 1985, Volume: 2, Issue:4

    Topics: Adult; Aerosols; Aged; Arrhythmias, Cardiac; Asthma; Cardiac Complexes, Premature; Drug Interactions

1985
[Ventricular arrhythmias in cor pulmonale. The effect of oxygen treatment].
    Deutsche medizinische Wochenschrift (1946), 1986, Apr-04, Volume: 111, Issue:14

    Topics: Aged; Arrhythmias, Cardiac; Blood Gas Analysis; Cardiac Complexes, Premature; Circadian Rhythm; Comb

1986
Arrhythmogenic effects of theophylline in human atrial tissue.
    International journal of cardiology, 1987, Volume: 17, Issue:3

    Topics: Adult; Arrhythmias, Cardiac; Calcium; Culture Techniques; Electrocardiography; Heart Atria; Heart Ra

1987
Comparison of the effects of isobutylmethylxanthine and milrinone on ischaemia-induced arrhythmias and platelet aggregation in anaesthetized rabbits.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bloo

1989
T wave inversion associated with severe theophylline toxicity.
    Chest, 1989, Volume: 96, Issue:2

    Topics: Adult; Arrhythmias, Cardiac; Asthma; Electrocardiography; Female; Heart Conduction System; Humans; T

1989
Effects of theophylline on inotropic and arrhythmogenic actions of cardiotonic steroids in guinea pig cardiac muscle.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Calcium; Digoxin; Dose-Response Relationship, Drug; Guinea Pigs; In V

1988
Lack of significant arrhythmogenicity from chronic theophylline and beta-2-adrenergic combination therapy in asthmatic subjects.
    Annals of allergy, 1985, Volume: 54, Issue:5

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Arrhythmias, Cardiac; Asthma; Atrial Function; De

1985
Proarrhythmia related to a kinetic and dynamic interaction of mexiletine and theophylline.
    American heart journal, 1989, Volume: 117, Issue:4

    Topics: Arrhythmias, Cardiac; Drug Interactions; Electrocardiography; Humans; Male; Mexiletine; Middle Aged;

1989
Cardiac arrhythmias during the combined use of intravenous aminophylline and terbutaline in status asthmaticus.
    Chest, 1988, Volume: 94, Issue:3

    Topics: Adult; Aged; Aminophylline; Arrhythmias, Cardiac; Asthma; Drug Therapy, Combination; Electrocardiogr

1988
[Amides of 7-theophyllineacetic acid with antiarrhythmic action].
    Acta poloniae pharmaceutica, 1987, Volume: 44, Issue:1

    Topics: Amides; Animals; Arrhythmias, Cardiac; Chemical Phenomena; Chemistry; Guinea Pigs; Rats; Theophyllin

1987
[Combined use of theophylline and ethylenediamine (aminophylline) and halothane in general anesthesia].
    Anaesthesiologie und Reanimation, 1986, Volume: 11, Issue:2

    Topics: Adult; Aminophylline; Anesthesia, General; Arrhythmias, Cardiac; Female; Halothane; Humans; Kinetics

1986
Epinephrine arrhythmogenicity is enhanced by acute, but not chronic, aminophylline administration during halothane anesthesia in dogs.
    Anesthesiology, 1986, Volume: 65, Issue:1

    Topics: Aminophylline; Anesthesia; Animals; Arrhythmias, Cardiac; Dogs; Epinephrine; Halothane; Male; Theoph

1986
[Fetal bigeminus following combined bronchodilator treatment of the mother].
    Geburtshilfe und Frauenheilkunde, 1986, Volume: 46, Issue:8

    Topics: Arrhythmias, Cardiac; Asthma; Drug Therapy, Combination; Electrocardiography; Female; Fetal Diseases

1986
Life-threatening theophylline toxicity is not predictable by serum levels.
    Chest, 1987, Volume: 91, Issue:1

    Topics: Aged; Arrhythmias, Cardiac; Female; Humans; Male; Medical Records; Middle Aged; Seizures; Theophylli

1987
[Manifestations of cardiac arrhythmia in halothane anesthesia in asthmatic patients treated with theophylline].
    Acta medica Iugoslavica, 1986, Volume: 40, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Arrhythmias, Cardiac; Asthma; Drug Interacti

1986
Reassessment of theophylline toxicity. Serum concentrations, clinical course, and treatment.
    Archives of internal medicine, 1987, Volume: 147, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Blood Glucose; Charcoal; Humans; Leukocyte Count; Middle Aged; Potassium

1987
Managing asthma and COPD in patients with cardiovascular disease.
    Geriatrics, 1985, Volume: 40, Issue:7

    Topics: Adult; Aged; Arrhythmias, Cardiac; Asthma; Cardiovascular Diseases; Digitalis; Digitalis Glycosides;

1985
[A patient with severe theophylline poisoning].
    Nederlands tijdschrift voor geneeskunde, 1985, Sep-07, Volume: 129, Issue:36

    Topics: Acidosis; Adult; Arrhythmias, Cardiac; Hemoperfusion; Humans; Male; Rhabdomyolysis; Seizures; Suicid

1985
Central beta-adrenoceptor sites and ouabain action.
    Pharmacological research communications, 1974, Volume: 6, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Bucladesine; Catecholamines; Cats; Cerebral Ventricle

1974
[Antiarrhythmic effect of sviomarin in experimental and clinical glycoside poisoning].
    Zeitschrift fur Kreislaufforschung, 1969, Volume: 58, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Digitalis Glycosides; Diphenhydramine; Dogs; Electrocardiography; Fem

1969
[Treatment of decompensated cor pulmonale with heptaminol theophyllineacetate].
    Munchener medizinische Wochenschrift (1950), 1972, Jul-07, Volume: 114, Issue:27

    Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Blood Pressure Determination; Cardiac Glyco

1972
[Etiology of heart rate disorders in the mature sheep fetus].
    Archiv fur Gynakologie, 1971, Jun-04, Volume: 211, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Carbon Dioxide; Female; Fetal Heart; Heart Rate; Hydr

1971
[Proscillaridine A in association with theophylline, ethylcrotylbarbituric acid and mecloxamine in clinical practice].
    Atti della Accademia dei fisiocritici in Siena. Sezione medico-fisica, 1967, Volume: 16, Issue:1

    Topics: Adult; Aged; Arrhythmias, Cardiac; Arteriosclerosis; Barbiturates; Cardiovascular Diseases; Coronary

1967
[On the drug therapy of arrhytmias].
    Die Medizinische Welt, 1966, Nov-19, Volume: 47

    Topics: Arrhythmias, Cardiac; Humans; Meprobamate; Phenobarbital; Phytotherapy; Plants, Medicinal; Procainam

1966
[The use of pyridophylline in a cardiology department].
    Marseille medical, 1966, Volume: 103, Issue:4

    Topics: Aged; Aortic Diseases; Arrhythmias, Cardiac; Arteritis; Coronary Disease; Female; Heart Diseases; Hu

1966