theophylline has been researched along with Anaphylactic Reaction in 55 studies
Excerpt | Relevance | Reference |
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"Previous studies suggest that high levels of adenosine may enhance histamine release and contribute to atrioventricular (AV) nodal conduction arrhythmias during anaphylaxis of isolated guinea pig hearts." | 7.67 | Role of adenosine in hypoxic alterations of anaphylaxis of isolated guinea pig hearts. ( Heller, LJ; Regal, JF; Trachte, GJ, 1989) |
"1 The inhibitory effects of sodium cromoglycate (SCG) and aminophylline on antigen-induced bronchial anaphylaxis in guinea-pigs, actively sensitized according to different regimens, were examined." | 7.66 | Antigen-induced bronchial anaphylaxis in actively sensitized guinea-pigs: anti-anaphylactic effects of sodium cromoglycate and aminophylline. ( Andersson, P, 1980) |
"Bronchial anaphylactic reactions, estimated as increase in intratracheal pressure, were precipitated by intravenous injections of antigen into actively sensitized SD rats." | 5.26 | Antigen-induced bronchial anaphylaxis in actively sensitized SD rats. Effects of immunization and provocation doses of antigen and of pretreatment with DSCG, theophylline, terbutaline and a new anti-allergic xanthine derivative, D4026. ( Dahlbäck, M, 1981) |
" Because leukotrienes are putative mediators of bronchial asthma, the effects of a lipoxygenase inhibitor, VZ564 (N-hydroxy-N-(6-methoxy-3,4-dihydro-2- naphthylmethyl) urea." | 3.69 | Effect of the lipoxygenase inhibitor N-hydroxy-N-(6-methoxy-3,4-dihydro-2-naphthylmethyl)urea on bronchoconstriction and lung vascular permeability in anaphylactic guinea pigs. ( Geist, C; Schneider, J; Zimmer, O, 1995) |
"Previous studies suggest that high levels of adenosine may enhance histamine release and contribute to atrioventricular (AV) nodal conduction arrhythmias during anaphylaxis of isolated guinea pig hearts." | 3.67 | Role of adenosine in hypoxic alterations of anaphylaxis of isolated guinea pig hearts. ( Heller, LJ; Regal, JF; Trachte, GJ, 1989) |
"Verapamil was found to be an effective inhibitor of isometric tension in in vitro, experimental anaphylaxis in guinea pig trachealis smooth muscle." | 3.66 | Effect of calcium antagonists in experimental asthma. ( Barbero, L; Markowicz, J; Weiss, EB, 1982) |
"1 The inhibitory effects of sodium cromoglycate (SCG) and aminophylline on antigen-induced bronchial anaphylaxis in guinea-pigs, actively sensitized according to different regimens, were examined." | 3.66 | Antigen-induced bronchial anaphylaxis in actively sensitized guinea-pigs: anti-anaphylactic effects of sodium cromoglycate and aminophylline. ( Andersson, P, 1980) |
" In conscious guinea pigs, pirbuterol antagonizes both histamine- and acetylcholine-induced bronchoconstriction and "microshock" anaphylaxis; combinations of pirbuterol and theophylline cause additive effects against histamine-induced bronchoconstriction." | 3.66 | Pirbuterol, a selecttve beta2 adrenergic bronchodilator. ( Barth, WE; Constantine, JW; Moore, PF, 1978) |
"These anaphylactic or anaphylactoid reactions are induced by the liberation of different mediators." | 2.40 | [Therapeutic measures for anaphylactic reactions in the course of allergen-specific immunotherapy]. ( Klimek, L, 1999) |
"Anaphylactic shock was consistently followed by metabolic acidosis." | 1.28 | Comparison of the anti-anaphylactic effects of milrinone, sulmazole and theophylline in the rat. ( Porsius, AJ; Post, MJ; te Biesebeek, JD; van Rooij, HH; Wemer, J, 1989) |
"Pretreatment with indomethacin abolished the preventive effects of theophylline on anaphylactic shock, and the effect of theophylline on the cyclic AMP content." | 1.26 | Preventive effects of theophylline on anaphylactic shock in rats. ( Okabe, E, 1980) |
"Bronchial anaphylactic reactions, estimated as increase in intratracheal pressure, were precipitated by intravenous injections of antigen into actively sensitized SD rats." | 1.26 | Antigen-induced bronchial anaphylaxis in actively sensitized SD rats. Effects of immunization and provocation doses of antigen and of pretreatment with DSCG, theophylline, terbutaline and a new anti-allergic xanthine derivative, D4026. ( Dahlbäck, M, 1981) |
" The dose-response relationships and kinetics of histamine and BK-A release from antigen-challenged peripheral leukocytes are similar." | 1.26 | Anaphylactic relase of a basophil kallikrein-like activity. II. A mediator of immediate hypersensitivity reactions. ( Lichtenstein, LM; Newball, HH; Talamo, RC, 1979) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 46 (83.64) | 18.7374 |
1990's | 7 (12.73) | 18.2507 |
2000's | 1 (1.82) | 29.6817 |
2010's | 1 (1.82) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Suzuki, F | 1 |
Kuroda, T | 1 |
Nakasato, Y | 1 |
Manabe, H | 1 |
Ohmori, K | 1 |
Kitamura, S | 1 |
Ichikawa, S | 1 |
Ohno, T | 1 |
Paul, R | 1 |
Brockman, JA | 1 |
Hallett, WA | 1 |
Hanifin, JW | 1 |
Tarrant, ME | 1 |
Torley, LW | 1 |
Callahan, FM | 1 |
Fabio, PF | 1 |
Johnson, BD | 1 |
Lenhard, RH | 1 |
Metz, G | 1 |
Pindell, MH | 1 |
Chen, HL | 1 |
Pfaar, O | 1 |
Klimek, L | 2 |
Mitsias, DI | 1 |
Vovolis, V | 1 |
MANCINI, L | 1 |
FRANCESCHINI, G | 1 |
FIRTH, A | 1 |
SMITH, WG | 2 |
RICHTER, W | 1 |
RUBINSTEIN, K | 1 |
ELMING, N | 1 |
BENNIKE, KA | 1 |
HAGELSTEN, JO | 1 |
HERXHEIMER, H | 1 |
STRESEMANN, E | 1 |
Grupe, R | 1 |
Pietzsch, W | 1 |
Hagen, V | 1 |
Göres, E | 1 |
Craps, L | 1 |
Bussolino, F | 1 |
Benveniste, J | 1 |
White, JR | 1 |
Pearce, FL | 2 |
Goto, K | 1 |
Hisadome, M | 1 |
Terasawa, M | 1 |
Weiss, EB | 1 |
Markowicz, J | 1 |
Barbero, L | 1 |
Bottomley, KM | 1 |
Lewis, S | 1 |
Rising, TJ | 1 |
Steward, A | 1 |
Okabe, E | 1 |
Dahlbäck, M | 1 |
Andersson, P | 1 |
Geist, C | 1 |
Schneider, J | 1 |
Zimmer, O | 1 |
Ahnefeld, FW | 1 |
Barth, J | 1 |
Dick, W | 1 |
Doenicke, A | 1 |
Fuchs, T | 1 |
Gervais, H | 1 |
Laubenthal, H | 1 |
Löllgen, H | 1 |
Lorenz, W | 1 |
Mehrkens, HH | 1 |
Craig, T | 1 |
Richerson, HB | 1 |
Moeckli, J | 1 |
Laekeman, GM | 1 |
Herman, AG | 1 |
Okazaki, T | 1 |
Okazaki, A | 1 |
Reisman, RE | 1 |
Arbesman, CE | 1 |
Liebig, R | 1 |
Bernauer, W | 1 |
Peskar, BA | 1 |
Blum, U | 1 |
Poblete-Freundt, G | 1 |
Schmutzler, W | 1 |
Mitchell, HW | 1 |
Hau, H | 1 |
Denborough, MA | 1 |
Foreman, JC | 1 |
Gomperts, BD | 1 |
Newball, HH | 1 |
Talamo, RC | 1 |
Lichtenstein, LM | 4 |
Moore, PF | 1 |
Constantine, JW | 1 |
Barth, WE | 1 |
Tarayre, JP | 1 |
Aliaga, M | 1 |
Barbara, M | 1 |
Malfetes, N | 1 |
Vieu, S | 1 |
Tisne-Versailles, J | 1 |
Walsh, DA | 1 |
Green, JB | 1 |
Franzyshen, SK | 1 |
Nolan, JC | 1 |
Yanni, JM | 1 |
Konno-Amano, S | 1 |
Hirao, T | 1 |
Kohno, H | 1 |
Mori, H | 1 |
Sato, Y | 1 |
Heller, LJ | 1 |
Trachte, GJ | 1 |
Regal, JF | 1 |
Post, MJ | 2 |
te Biesebeek, JD | 2 |
Wemer, J | 2 |
van Rooij, HH | 2 |
Porsius, AJ | 2 |
Morris, EC | 1 |
Berti, F | 1 |
Magni, F | 1 |
Rossoni, G | 1 |
Schiantarelli, P | 1 |
Bongrani, S | 1 |
Pasargiklian, R | 1 |
Levy, DA | 1 |
Ishizaka, K | 3 |
Ishizaka, T | 2 |
Orange, RP | 1 |
Austen, KF | 1 |
De Bernardo, R | 1 |
Broder, I | 2 |
Baumal, R | 1 |
Grant, JA | 1 |
Tomioka, H | 1 |
Yamamoto, S | 1 |
Greaves, MW | 1 |
Fairley, VM | 1 |
Fullarton, J | 1 |
Martin, LE | 1 |
Vardey, C | 1 |
Taylor, WA | 1 |
Francis, DH | 1 |
Sheldon, D | 1 |
Roitt, IM | 1 |
Eilbeck, JF | 1 |
LeDouarec, JC | 1 |
Duhault, J | 1 |
Laubie, M | 1 |
Giertz, H | 1 |
Mitze, U | 1 |
Levi, R | 1 |
Sheffer, AL | 1 |
6 reviews available for theophylline and Anaphylactic Reaction
Article | Year |
---|---|
[Anaphylaxis--life-threatening allergic reactions].
Topics: Adrenergic Agonists; Allergens; Anaphylaxis; Child; Emergencies; Epinephrine; Glucocorticoids; Hista | 2008 |
[Ketotifen in the prevention of bronchial asthma. International therapeutic evaluation].
Topics: Adrenal Cortex Hormones; Adult; Anaphylaxis; Asthma; Bronchial Provocation Tests; Bronchodilator Age | 1981 |
[Acute therapy of anaphylactoid reactions. Results of an intradisciplinary consensus conference].
Topics: Anaphylaxis; Calcium; Catecholamines; Histamine Antagonists; Humans; Plasma Substitutes; Theophyllin | 1994 |
Problem drugs for the patient with asthma.
Topics: Adrenergic beta-Antagonists; Anaphylaxis; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammator | 1996 |
[Therapeutic measures for anaphylactic reactions in the course of allergen-specific immunotherapy].
Topics: Anaphylaxis; Bronchodilator Agents; Calcium; Catecholamines; Contraindications; Desensitization, Imm | 1999 |
Pharmacotherapy of allergic disease.
Topics: Adrenal Cortex Hormones; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Aged; Anaphylax | 1987 |
1 trial available for theophylline and Anaphylactic Reaction
Article | Year |
---|---|
[Ketotifen in the prevention of bronchial asthma. International therapeutic evaluation].
Topics: Adrenal Cortex Hormones; Adult; Anaphylaxis; Asthma; Bronchial Provocation Tests; Bronchodilator Age | 1981 |
49 other studies available for theophylline and Anaphylactic Reaction
Article | Year |
---|---|
New bronchodilators. 1. 1,5-Substituted 1H-imidazo[4,5-c]quinolin-4(5H)-ones.
Topics: Airway Resistance; Anaphylaxis; Animals; Bronchodilator Agents; Guinea Pigs; Heart; Imidazoles; In V | 1992 |
Imidazo[1,5-d][1,2,4]triazines as potential antiasthma agents.
Topics: Anaphylaxis; Animals; Asthma; Basophils; Chemical Phenomena; Chemistry; Guinea Pigs; Histamine Relea | 1985 |
Cloxacepride and related compounds: a new series of orally active antiallergic compounds.
Topics: Administration, Oral; Anaphylaxis; Animals; Benzamides; Female; Histamine H1 Antagonists; Indicators | 1983 |
Anaphylaxis to dimenhydrinate caused by the theophylline component.
Topics: Adult; Allergens; Anaphylaxis; Antiemetics; Dimenhydrinate; Drug Combinations; Female; Humans; Skin | 2011 |
[Effect of theophylline-ethylenediamine on anaphylactic shock in rabbits].
Topics: Aminophylline; Anaphylaxis; Animals; Ethylenediamines; Humans; Hypersensitivity; Rabbits; Shock; The | 1955 |
THE ANTI-ANAPHYLACTIC ACTIVITY OF THEOPHYLLINE AND SOME RELATED XANTHINE DERIVATIVES.
Topics: Anaphylaxis; Anti-Allergic Agents; Caffeine; Diuretics; Guinea Pigs; Histamine H1 Antagonists; Hista | 1964 |
ANAPHYLACTIC MICROSHOCK IN THE SCREENING OF SOME THEOPHYLLINES AND BENZYLPHENOXYAMINOALKANES FOR ANTIASTHMATIC ACTIVITY.
Topics: Aminophylline; Anaphylaxis; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Chemistry, | 1963 |
[ALLERGY AND ANESTHESIA].
Topics: Adrenal Cortex Hormones; Allergens; Anaphylaxis; Anesthesia; Anesthetics; Drug Hypersensitivity; Dru | 1964 |
Protection against anaphylactic shock by ephedrine-theophylline combinations.
Topics: Anaphylaxis; Ephedrine; Humans; Hypersensitivity; Immune System Diseases; Theophylline | 1960 |
[The antianaphylactic effect of derivatives of 4-oxoquinazoline, 4-oxoquinazol-3-yl-benzoic acid and 4-oxoquinazol-3-yl-acetic acid in the rat].
Topics: Anaphylaxis; Animals; Bordetella pertussis; Chemical Phenomena; Chemistry; Kinetics; Passive Cutaneo | 1984 |
Pharmacological modulation of platelet-activating factor (PAF) release from rabbit leucocytes. I. Role of cAMP.
Topics: Anaphylaxis; Animals; Antigens; Basophils; Blood Platelets; Bucladesine; Cyclic AMP; Dose-Response R | 1980 |
Effect of anti-allergic compounds on anaphylactic histamine secretion from rat peritoneal mast cells in the presence and absence of exogenous calcium.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Anaphylaxis; Animals; Ascitic Fluid; Bronchodilator Agents; | 1982 |
Inhibitory effect of traxanox sodium on IgE-mediated histamine release from passively-sensitized mast cells of the rat in vitro.
Topics: Anaphylaxis; Animals; Calcium; Chromones; Cromolyn Sodium; Dose-Response Relationship, Immunologic; | 1982 |
Effect of calcium antagonists in experimental asthma.
Topics: Anaphylaxis; Animals; Asthma; Calcium Channel Blockers; Depression, Chemical; Disease Models, Animal | 1982 |
A new in vivo method for the measurement of repetitive anaphylactic responses in the guinea-pig.
Topics: Albuterol; Anaphylaxis; Animals; Antibodies; Cromolyn Sodium; Dimaprit; Guinea Pigs; Male; Pyrilamin | 1984 |
Preventive effects of theophylline on anaphylactic shock in rats.
Topics: Anaphylaxis; Animals; Cyclic AMP; Histamine; Indomethacin; Lung; Male; Prostaglandins E; Rats; Theop | 1980 |
Antigen-induced bronchial anaphylaxis in actively sensitized SD rats. Effects of immunization and provocation doses of antigen and of pretreatment with DSCG, theophylline, terbutaline and a new anti-allergic xanthine derivative, D4026.
Topics: Adjuvants, Immunologic; Aluminum Hydroxide; Anaphylaxis; Animals; Antigens; Bronchial Spasm; Cromoly | 1981 |
Antigen-induced bronchial anaphylaxis in actively sensitized guinea-pigs: anti-anaphylactic effects of sodium cromoglycate and aminophylline.
Topics: Aminophylline; Anaphylaxis; Animals; Bronchial Spasm; Cromolyn Sodium; Female; Guinea Pigs; Male; Ov | 1980 |
Effect of the lipoxygenase inhibitor N-hydroxy-N-(6-methoxy-3,4-dihydro-2-naphthylmethyl)urea on bronchoconstriction and lung vascular permeability in anaphylactic guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Bronchoconstriction; Capillary Permeability; Guinea Pigs; In Vitro Tec | 1995 |
The Schultz-Dale reaction of the guinea-pig ileum: influence by beta-adrenoceptor agonists and theophylline.
Topics: Adrenergic beta-Agonists; Albuterol; Anaphylaxis; Animals; Dose-Response Relationship, Drug; Female; | 1979 |
Glycogenolysis and control of anaphylactic histamine release by cyclic adenosine monophosphate-related agents. II. Modification of histamine release by glycogenolytic metabolites.
Topics: Anaphylaxis; Animals; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Female; | 1975 |
Prostaglandin, slow-reacting substance, and histamine release from anaphylactic guinea-pig hearts, and its pharmacological modification.
Topics: Anaphylaxis; Animals; Coronary Circulation; Female; Guinea Pigs; Heart Rate; Histamine Release; In V | 1975 |
Studies on the release of histamine from isolated guinea pig mast cells stimulated by ionophore A23187 or by the anaphylactic reaction.
Topics: Anaphylaxis; Animals; Anti-Bacterial Agents; Calcimycin; Calcium; Cromolyn Sodium; Cyclic AMP; Guine | 1978 |
In vitro action of combined salbutamol and theophylline on anaphylactic contractions, mediator release and cyclic 3',5'-adenosine monophosphate in lung parenchyma.
Topics: Albuterol; Anaphylaxis; Animals; Cyclic AMP; Guinea Pigs; Histamine Release; In Vitro Techniques; In | 1979 |
The relationship between anaphylactic histamine secretion and the permability of the mast cell membrane to calcium.
Topics: Anaphylaxis; Antigen-Antibody Reactions; Bucladesine; Calcimycin; Calcium; Cell Membrane Permeabilit | 1975 |
Anaphylactic relase of a basophil kallikrein-like activity. II. A mediator of immediate hypersensitivity reactions.
Topics: Anaphylaxis; Antibodies; Arginine; Basophils; Bucladesine; Calcimycin; Colchicine; Deoxyglucose; Deu | 1979 |
Pirbuterol, a selecttve beta2 adrenergic bronchodilator.
Topics: Acetylcholine; Albuterol; Anaphylaxis; Animals; Bronchodilator Agents; Cardiovascular System; Dogs; | 1978 |
Theophylline reduces pulmonary eosinophilia after various types of active anaphylactic shock in guinea-pigs.
Topics: Aerosols; Anaphylaxis; Animals; Bronchitis; Bronchoalveolar Lavage Fluid; Eosinophils; Guinea Pigs; | 1991 |
Synthesis and antiallergy activity of N-[2-(dimethylamino)ethyl]-4-aryl-1-piperazinecarboxamide derivatives.
Topics: Anaphylaxis; Animals; Dimethylamines; Disease Models, Animal; Guinea Pigs; Histamine H1 Antagonists; | 1990 |
Passive air-pouch anaphylaxis in rats. II. Pharmacological characterization.
Topics: Adult; Air; Anaphylaxis; Animals; Capillary Permeability; Chromones; Cromolyn Sodium; Dexamethasone; | 1989 |
Role of adenosine in hypoxic alterations of anaphylaxis of isolated guinea pig hearts.
Topics: Adenosine; Anaphylaxis; Animals; Antigens; Atrioventricular Node; Coronary Circulation; Guinea Pigs; | 1989 |
In vivo anaphylaxis in the rat: effects of phosphodiesterase inhibitors.
Topics: Anaphylaxis; Animals; Antigens; Cardiovascular System; Imidazoles; Lung; Male; Milrinone; Phosphodie | 1989 |
Comparison of the anti-anaphylactic effects of milrinone, sulmazole and theophylline in the rat.
Topics: Acid-Base Equilibrium; Airway Resistance; Anaphylaxis; Animals; Imidazoles; Lung Compliance; Male; M | 1989 |
New pharmacological data on the bronchospasmolytic activity of bamifylline.
Topics: Acetylcholine; Airway Resistance; Anaphylaxis; Animals; Bronchodilator Agents; Guinea Pigs; Histamin | 1988 |
In vitro reversed anaphylaxis: characteristics of anti-IgE mediated histamine release.
Topics: Anaphylaxis; Animals; Antibodies, Anti-Idiotypic; Antigens; Colchicine; Cyclic AMP; gamma-Globulins; | 1970 |
Pharmacologic inhibition of the antigen-induced release of histamine and slow reacting substance of anaphylaxis (SRS-A) from monkey lung tissues mediated by human IgE.
Topics: Anaphylaxis; Animals; Antigen-Antibody Reactions; Cyclic AMP; Diethylcarbamazine; Drug Synergism; Ep | 1971 |
IgE mediated histamine release: in vitro separation into two phases.
Topics: Adenine Nucleotides; Anaphylaxis; Antigen-Antibody Reactions; Antigens; Autacoids; Basophils; Buffer | 1971 |
Studies of reversed anaphylaxis in the perfused guinea-pig lung.
Topics: Anaphylaxis; Animals; Antigen-Antibody Reactions; Calcium; Electrophoresis; Epinephrine; Ethylmaleim | 1972 |
Reversed in vitro anaphylaxis induced by anti-IgG: specificity of the reaction and comparison with antigen-induced histamine release.
Topics: Anaphylaxis; Antibodies, Anti-Idiotypic; Antibody Specificity; Antigens; Cells, Cultured; Chromatogr | 1972 |
Release of histamine and slow reacting substance of anaphylaxis (SRS-A) by IgE-anti-IgE reactions on monkey mast cells.
Topics: Anaphylaxis; Animals; Antigen-Antibody Reactions; Autacoids; Autoradiography; Edetic Acid; Histamine | 1972 |
Cyclic AMP-induced inhibition of IgE-mediated hypersensitivity in human skin.
Topics: Anaphylaxis; Animals; Antigens; Biological Assay; Cyclic AMP; Depression, Chemical; Dose-Response Re | 1973 |
Mechanism of histamine release from guinea-pig lung by soluble immune complexes. II. Role of anaphylatoxin.
Topics: Anaphylaxis; Animals; Antigen-Antibody Complex; Biological Assay; Dose-Response Relationship, Drug; | 1974 |
Studies on the inhibition of cellular anaphylaxis.
Topics: Anaphylaxis; Animals; Antibodies; Antigens; Butylamines; Carboxylic Acids; Cromolyn Sodium; Dinitrop | 1973 |
The anti-anaphylactic actions of disodium cromoglycate, theophylline, isoprenaline and prostaglandins.
Topics: Anaphylaxis; Animals; Ascitic Fluid; Bucladesine; Cromolyn Sodium; Cytoplasmic Granules; Immune Sera | 1974 |
Histamine release from the mast cells of guinea-pig lung.
Topics: Amino Alcohols; Anaphylaxis; Animals; Antigens; Egg White; Guinea Pigs; Histamine; Hydrocortisone; L | 1967 |
[Pharmacological study of phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2 hydrochloride or fenspiride (JP 428)].
Topics: Anaphylaxis; Anesthesia; Animals; Anti-Inflammatory Agents; Atropine; Autonomic Nervous System; Bron | 1969 |
[The effects of theophylline, isoprenaline, orciprenaline and dexamethasone on the protracted anaphylactic shock of the guinea pig].
Topics: Anaphylaxis; Animals; Dexamethasone; Female; Guinea Pigs; Histamine H1 Antagonists; Isoproterenol; M | 1970 |
Hypersensitivity reactions of the heart: reduction of anaphylactic crisis by theophylline or glucagon.
Topics: Anaphylaxis; Animals; Glucagon; Guinea Pigs; Heart; Histamine H1 Antagonists; In Vitro Techniques; M | 1971 |
Treatment of anaphylaxis.
Topics: Anaphylaxis; Desensitization, Immunologic; Diphenhydramine; Drug Hypersensitivity; Ephedrine; Epinep | 1973 |