Page last updated: 2024-10-22

theophylline and Altitude Sickness

theophylline has been researched along with Altitude Sickness in 10 studies

Altitude Sickness: Multiple symptoms associated with reduced oxygen at high ALTITUDE.

Research Excerpts

ExcerptRelevanceReference
"What is the central question of this study? Does the combination of methazolamide and theophylline reduce symptoms of acute mountain sickness (AMS) and improve aerobic performance in acute hypobaric hypoxia? What is the main finding and its importance? The oral combination of methazolamide (100 BID) and theophylline (300 BID) improved arterial oxygen saturation but did not reduce symptoms of AMS and impaired aerobic performance."8.02Combined methazolamide and theophylline improves oxygen saturation but not exercise performance or altitude illness in acute hypobaric hypoxia. ( Davis, C; Evero, O; Gronewold, J; Nichols, AJ; Reitinger, J; Roach, RC; Subudhi, AW; Van-Houten, SJ, 2021)
"High-altitude pulmonary edema reflects a potentially life-threatening condition affecting susceptible persons in the second night after ascent to altitudes above 2500 m."5.31Are sildenafil and theophylline effective in the prevention of high-altitude pulmonary edema? ( Kleinsasser, A; Loeckinger, A, 2002)
"What is the central question of this study? Does the combination of methazolamide and theophylline reduce symptoms of acute mountain sickness (AMS) and improve aerobic performance in acute hypobaric hypoxia? What is the main finding and its importance? The oral combination of methazolamide (100 BID) and theophylline (300 BID) improved arterial oxygen saturation but did not reduce symptoms of AMS and impaired aerobic performance."4.02Combined methazolamide and theophylline improves oxygen saturation but not exercise performance or altitude illness in acute hypobaric hypoxia. ( Davis, C; Evero, O; Gronewold, J; Nichols, AJ; Reitinger, J; Roach, RC; Subudhi, AW; Van-Houten, SJ, 2021)
"Acute mountain sickness was significantly reduced by theophylline during the decompression chamber study (mean+/-SD 1."2.69Theophylline improves acute mountain sickness. ( Fischer, R; Hautmann, H; Huber, RM; Lang, SM; Pongratz, H; Steiner, U; Toepfer, M, 2000)
"High-altitude pulmonary edema reflects a potentially life-threatening condition affecting susceptible persons in the second night after ascent to altitudes above 2500 m."1.31Are sildenafil and theophylline effective in the prevention of high-altitude pulmonary edema? ( Kleinsasser, A; Loeckinger, A, 2002)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (80.00)29.6817
2010's1 (10.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Subudhi, AW1
Evero, O1
Reitinger, J1
Davis, C1
Gronewold, J1
Nichols, AJ1
Van-Houten, SJ1
Roach, RC1
Ghosh, M1
Biswas, D1
Mukherjee, A1
Kleinsasser, A1
Loeckinger, A1
Fischer, R4
Vollmar, C1
Thiere, M2
Born, C1
Leitl, M2
Pfluger, T1
Huber, RM4
Lang, SM3
Steiner, U2
Bartsch, P1
Bailey, DM1
Berger, MM1
Knauth, M1
Baumgartner, RW1
Sanner, B1
Schäfer, T1
Toepfer, M1
Hautmann, H1
Pongratz, H1
Röggla, G1
Domej, W1
Röggla, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of High-altitude Sleep Disturbance: A Double-blind Comparison of Temazepam Versus Acetazolamide.[NCT01519544]34 participants (Actual)Interventional2012-03-31Completed
Observational Study of Skin Erythema by Spectrophotometer, and UV Exposure With Viospore Ultraviolet Monitors at Extreme Altitude (Mt. Everest, North Side)[NCT00685438]25 participants (Actual)Observational2007-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for theophylline and Altitude Sickness

ArticleYear
Acute mountain sickness: controversies and advances.
    High altitude medicine & biology, 2004,Summer, Volume: 5, Issue:2

    Topics: Acetazolamide; Altitude Sickness; Brain Edema; Carbonic Anhydrase Inhibitors; Dose-Response Relation

2004
[Central sleep apnea syndrome].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:14

    Topics: Acetazolamide; Altitude Sickness; Anticonvulsants; Bronchodilator Agents; Cardiovascular Diseases; C

2008

Trials

4 trials available for theophylline and Altitude Sickness

ArticleYear
No evidence of cerebral oedema in severe acute mountain sickness.
    Cephalalgia : an international journal of headache, 2004, Volume: 24, Issue:1

    Topics: Acetazolamide; Altitude Sickness; Brain; Brain Edema; Cross-Over Studies; Double-Blind Method; Human

2004
Theophylline and acetazolamide reduce sleep-disordered breathing at high altitude.
    The European respiratory journal, 2004, Volume: 23, Issue:1

    Topics: Acetazolamide; Administration, Oral; Altitude; Altitude Sickness; Apnea; Autacoids; Blood Gas Analys

2004
Theophylline improves acute mountain sickness.
    The European respiratory journal, 2000, Volume: 15, Issue:1

    Topics: Administration, Oral; Adult; Altitude Sickness; Cross-Over Studies; Decompression; Delayed-Action Pr

2000
Does theophylline really improve acute mountain sickness?
    The European respiratory journal, 2001, Volume: 17, Issue:3

    Topics: Acute Disease; Adenosine; Adult; Altitude Sickness; Cross-Over Studies; Double-Blind Method; Humans;

2001

Other Studies

4 other studies available for theophylline and Altitude Sickness

ArticleYear
Combined methazolamide and theophylline improves oxygen saturation but not exercise performance or altitude illness in acute hypobaric hypoxia.
    Experimental physiology, 2021, Volume: 106, Issue:1

    Topics: Acute Disease; Adult; Altitude; Altitude Sickness; Cross-Over Studies; Double-Blind Method; Exercise

2021
High-altitude medicines: a short-term genotoxicity study.
    Toxicology and industrial health, 2010, Volume: 26, Issue:7

    Topics: Acetazolamide; Adult; Altitude Sickness; Analysis of Variance; Cell Survival; Cells, Cultured; Comet

2010
Are sildenafil and theophylline effective in the prevention of high-altitude pulmonary edema?
    Medical hypotheses, 2002, Volume: 59, Issue:2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Altitude Sickness; Cyclic Nucleotide Phosphodiesterases, Type 5

2002
Does theophylline really improve acute mountain sickness?
    The European respiratory journal, 2001, Volume: 17, Issue:5

    Topics: Altitude Sickness; Carbon Dioxide; Cross-Over Studies; Double-Blind Method; Humans; Oxygen; Randomiz

2001