theophylline has been researched along with Adverse Drug Event in 35 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We presume it necessary to pay heed to fever and neurologic predispositions in order to prevent sequelae or death that may occur subsequently to seizures that developed during theophylline administration." | 7.74 | [Clinical review of patients with seizures that developed during theophylline administration--(III) Safety of theophylline examined in patients who had sequelae or died]. ( Kato, T; Nakano, H; Odajima, Y; Okada, K, 2008) |
| ", doses of individual drugs) that induced seizure-like events, and identified diphenhydramine, enoxacin, strychnine and theophylline as "seizure-inducing" drugs, which have indeed been reported to induce seizures in clinical situations." | 4.98 | [Machine Learning-based Prediction of Seizure-inducing Action as an Adverse Drug Effect]. ( Gao, M; Ikegaya, Y; Sato, M, 2018) |
| "The period prevalence of patients at risk of a potentially highly significant medication-smoking cessation interaction was 23/48 (48%), 66/256 (26%) and 1/16 (6%) amongst smokers prescribed clozapine, olanzapine or theophylline, respectively." | 3.91 | Prevalence and recognition of highly significant medication-smoking cessation interactions in a smoke-free hospital. ( Chui, CY; George, J; Taylor, SE; Thomas, D, 2019) |
| "We presume it necessary to pay heed to fever and neurologic predispositions in order to prevent sequelae or death that may occur subsequently to seizures that developed during theophylline administration." | 3.74 | [Clinical review of patients with seizures that developed during theophylline administration--(III) Safety of theophylline examined in patients who had sequelae or died]. ( Kato, T; Nakano, H; Odajima, Y; Okada, K, 2008) |
| " In the meantime, health care providers and pregnant women must work with the information that is available to evaluate the risks and benefits of a particular medication and alternative choices for treatment of asthma or allergy during pregnancy, while considering the potential for adverse effects if the woman with severe or uncontrolled asthma is under-treated." | 2.43 | Safety of asthma and allergy medications in pregnancy. ( Chambers, C, 2006) |
| "Seizures are commonly encountered in patients who do not have epilepsy." | 2.40 | Medical causes of seizures. ( Delanty, N; French, JA; Vaughan, CJ, 1998) |
| "Aminophylline injection has been on an intermittent nation-wide shortage due to manufacturing delays leaving a need for an alternative reversal agent for regadenoson-associated side effects." | 1.91 | Safety and efficacy of IV theophylline for regadenoson-associated side effect reversal. ( Page, RL; Pham, VA; Quaife, RA; Raines, J; Shakowski, C, 2023) |
| " Interactions may occur between drugs used in combination to treat various diseases and may cause adverse events (AEs)." | 1.72 | Analysis of drug adverse events in elderly patients based on the Japanese Adverse Drug Event Report Database. ( Nagai, N; Okada, A; Sera, S; Taguchi, M; Yamada, H, 2022) |
| " In particular, a global optimization control strategy is implemented to obtain the optimal dosage regimen, and weighting functions are introduced to balance the drug efficacy and the risk of toxicity." | 1.34 | Weighted target interval stochastic control methods with global optimization and their applications in individualizing therapy. ( Ji, S; Lee, EJ; Wu, P; Zeng, Y, 2007) |
| "5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects." | 1.32 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004) |
| "gentamicin therapy were randomly selected and monitored for possible ADRs." | 1.27 | Sensitivity and specificity of three methods of detecting adverse drug reactions. ( Berry, LL; Fudge, KA; Segal, R; Sherrin, TP, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (28.57) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 7 (20.00) | 29.6817 |
| 2010's | 8 (22.86) | 24.3611 |
| 2020's | 5 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Matthews, EJ | 1 |
| Kruhlak, NL | 1 |
| Weaver, JL | 1 |
| Benz, RD | 1 |
| Contrera, JF | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Purpura, M | 1 |
| Jäger, R | 1 |
| Falk, M | 1 |
| Cole, JB | 1 |
| Meiners, RB | 1 |
| Bangh, SA | 1 |
| Okada, A | 1 |
| Sera, S | 1 |
| Taguchi, M | 1 |
| Yamada, H | 1 |
| Nagai, N | 1 |
| Shakowski, C | 1 |
| Pham, VA | 1 |
| Raines, J | 1 |
| Quaife, RA | 1 |
| Page, RL | 1 |
| Oxley-Oxland, JV | 3 |
| Freercks, R | 3 |
| Baker, D | 3 |
| Van der Merwe, E | 3 |
| Gao, M | 1 |
| Sato, M | 1 |
| Ikegaya, Y | 1 |
| Chui, CY | 1 |
| Taylor, SE | 1 |
| Thomas, D | 1 |
| George, J | 1 |
| Gosch, M | 1 |
| Dovjak, P | 1 |
| Odajima, Y | 1 |
| Nakano, H | 1 |
| Kato, T | 1 |
| Okada, K | 1 |
| Chu, CC | 1 |
| Pan, KL | 1 |
| Yao, HT | 1 |
| Hsu, JT | 1 |
| Kwok, CS | 1 |
| Pang, CL | 1 |
| Yeong, JK | 1 |
| Loke, YK | 1 |
| Hadaway, LC | 1 |
| Venkataraman, R | 1 |
| Chambers, C | 1 |
| Ji, S | 1 |
| Zeng, Y | 1 |
| Wu, P | 1 |
| Lee, EJ | 1 |
| Yang, ZN | 1 |
| Wu, Y | 1 |
| Pu, HP | 1 |
| Clark, BG | 1 |
| Vestal, RE | 1 |
| Mougeot, G | 1 |
| Hugues, FC | 1 |
| D'Arcy, PF | 1 |
| Ciummo, PE | 1 |
| Katz, NL | 1 |
| Delanty, N | 1 |
| Vaughan, CJ | 1 |
| French, JA | 1 |
| Hammond, KB | 1 |
| Grammer, LC | 1 |
| Schumacher, GE | 1 |
| Barr, JT | 1 |
| Tschepik, W | 1 |
| Segal, R | 2 |
| Sherrin, TP | 2 |
| Schneider, DN | 1 |
| Hammond, RL | 1 |
| Berry, LL | 1 |
| Fudge, KA | 1 |
| Junge, N | 1 |
| Jordan, D | 1 |
| Thurn, G | 1 |
| Alter, HG | 1 |
| Niebergall, PJ | 1 |
| Sugita, ET | 1 |
| Schnaare, RL | 1 |
8 reviews available for theophylline and Adverse Drug Event
| Article | Year |
|---|---|
[Machine Learning-based Prediction of Seizure-inducing Action as an Adverse Drug Effect].
Topics: Animals; Diphenhydramine; Drug Discovery; Drug Evaluation, Preclinical; Drug-Related Side Effects an | 2018 |
Measures used to treat contrast-induced nephropathy: overview of reviews.
Topics: Acetylcysteine; Drug-Related Side Effects and Adverse Reactions; Humans; Hydroxymethylglutaryl-CoA R | 2013 |
Prevention of acute renal failure.
Topics: Acetylcysteine; Acute Kidney Injury; Diuretics; Dopamine Agents; Drug-Related Side Effects and Adver | 2005 |
Safety of asthma and allergy medications in pregnancy.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Allergic Agents; Anti-Asthmatic Agents; Asth | 2006 |
Vaccine-drug interactions.
Topics: Aminopyrine; BCG Vaccine; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans | 1984 |
Medical causes of seizures.
Topics: Acute Kidney Injury; Anticonvulsants; Antitubercular Agents; Blood Pressure; Brain Diseases; Broncho | 1998 |
Drugs and children: methods for therapeutic monitoring.
Topics: Carbamazepine; Child; Child, Preschool; Chloramphenicol; Chromatography, Gas; Colorimetry; Drug Ther | 1977 |
Basic pharmacotherapy for asthma.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Asthma; Clinical Protocols; Cromolyn Sodium; Drug | 1992 |
1 trial available for theophylline and Adverse Drug Event
| Article | Year |
|---|---|
[Comparative study on the clinical efficacy and safety of inhaled corticosteroid combined with slow-release theophylline compared to seretide in the control of asthma in children].
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Asthma; Child; Child, Preschool; Drug Interacti | 2007 |
26 other studies available for theophylline and Adverse Drug Event
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru | 2004 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
An assessment of mutagenicity, genotoxicity, acute-, subacute and subchronic oral toxicity of paraxanthine (1,7-dimethylxanthine).
Topics: Administration, Oral; Animals; Drug-Related Side Effects and Adverse Reactions; Female; Male; Mutage | 2021 |
Fluvoxamine used to treat COVID-19 resulting in theophylline toxicity from CYP 1A2 drug-drug interaction.
Topics: COVID-19 Drug Treatment; Cytochrome P-450 CYP1A2; Drug Interactions; Drug-Related Side Effects and A | 2022 |
Analysis of drug adverse events in elderly patients based on the Japanese Adverse Drug Event Report Database.
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Anticoagulants; Cross-Sectional Studies; Drug-Related | 2022 |
Safety and efficacy of IV theophylline for regadenoson-associated side effect reversal.
Topics: Aminophylline; Drug-Related Side Effects and Adverse Reactions; Humans; Purines; Pyrazoles; Theophyl | 2023 |
The characteristics and costs of severe theophylline toxicity in a tertiary critical care unit in Eastern Cape Province, South Africa.
Topics: Adult; Creatinine; Critical Care; Drug-Related Side Effects and Adverse Reactions; Female; Humans; I | 2022 |
The characteristics and costs of severe theophylline toxicity in a tertiary critical care unit in Eastern Cape Province, South Africa.
Topics: Adult; Creatinine; Critical Care; Drug-Related Side Effects and Adverse Reactions; Female; Humans; I | 2022 |
The characteristics and costs of severe theophylline toxicity in a tertiary critical care unit in Eastern Cape Province, South Africa.
Topics: Adult; Creatinine; Critical Care; Drug-Related Side Effects and Adverse Reactions; Female; Humans; I | 2022 |
The characteristics and costs of severe theophylline toxicity in a tertiary critical care unit in Eastern Cape Province, South Africa.
Topics: Adult; Creatinine; Critical Care; Drug-Related Side Effects and Adverse Reactions; Female; Humans; I | 2022 |
The characteristics and costs of severe theophylline toxicity in a tertiary critical care unit in Eastern Cape Province, South Africa.
Topics: Adult; Creatinine; Critical Care; Drug-Related Side Effects and Adverse Reactions; Female; Humans; I | 2022 |
The characteristics and costs of severe theophylline toxicity in a tertiary critical care unit in Eastern Cape Province, South Africa.
Topics: Adult; Creatinine; Critical Care; Drug-Related Side Effects and Adverse Reactions; Female; Humans; I | 2022 |
The characteristics and costs of severe theophylline toxicity in a tertiary critical care unit in Eastern Cape Province, South Africa.
Topics: Adult; Creatinine; Critical Care; Drug-Related Side Effects and Adverse Reactions; Female; Humans; I | 2022 |
The characteristics and costs of severe theophylline toxicity in a tertiary critical care unit in Eastern Cape Province, South Africa.
Topics: Adult; Creatinine; Critical Care; Drug-Related Side Effects and Adverse Reactions; Female; Humans; I | 2022 |
The characteristics and costs of severe theophylline toxicity in a tertiary critical care unit in Eastern Cape Province, South Africa.
Topics: Adult; Creatinine; Critical Care; Drug-Related Side Effects and Adverse Reactions; Female; Humans; I | 2022 |
Prevalence and recognition of highly significant medication-smoking cessation interactions in a smoke-free hospital.
Topics: Adult; Aged; Australia; Clozapine; Cross-Sectional Studies; Delivery of Health Care; Drug-Related Si | 2019 |
[Digitalis and theophylline: old and superfluous?].
Topics: Aged; Aged, 80 and over; Comorbidity; Digitalis Glycosides; Drug-Related Side Effects and Adverse Re | 2013 |
[Clinical review of patients with seizures that developed during theophylline administration--(III) Safety of theophylline examined in patients who had sequelae or died].
Topics: Age Factors; Child; Child, Preschool; Communicable Diseases; Drug-Related Side Effects and Adverse R | 2008 |
Development of a whole-cell screening system for evaluation of the human CYP1A2-mediated metabolism.
Topics: Berberine; Cell Line; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Drug Evaluation, | 2011 |
Managing i.v. therapy: "high-alert" drugs keep nurse managers ever watchful.
Topics: Anticoagulants; Bronchodilator Agents; Cardiotonic Agents; Dopamine; Drug Incompatibility; Drug Moni | 2000 |
Weighted target interval stochastic control methods with global optimization and their applications in individualizing therapy.
Topics: Algorithms; Bayes Theorem; Computer Simulation; Drug Therapy; Drug-Related Side Effects and Adverse | 2007 |
Adverse drug reactions in the elderly: case studies.
Topics: Acetazolamide; Aged; Anemia, Hemolytic; Bromocriptine; Captopril; Chlorpropamide; Cimetidine; Clonid | 1984 |
[Drugs and the cardiovascular system].
Topics: Adrenergic beta-Antagonists; Anesthetics; Angina Pectoris; Animals; Anti-Arrhythmia Agents; Antineop | 1982 |
Interactions and drug-metabolizing enzymes.
Topics: Adolescent; Adult; Anti-Allergic Agents; Antidepressive Agents, Second-Generation; Antifungal Agents | 1995 |
Drugs in the elderly.
Topics: Aged; Analgesics; Anti-Bacterial Agents; Anticoagulants; Antihypertensive Agents; Digoxin; Diuretics | 1979 |
Using population-based serum drug concentration cutoff values to predict toxicity: test performance and limitations compared with Bayesian interpretation.
Topics: Aminoglycosides; Bayes Theorem; Digoxin; Drug-Related Side Effects and Adverse Reactions; False Nega | 1990 |
Therapeutic risk-assessment model for identifying patients with adverse drug reactions.
Topics: Digoxin; Drug-Related Side Effects and Adverse Reactions; Hospital Bed Capacity, 500 and over; Human | 1990 |
Sensitivity and specificity of three methods of detecting adverse drug reactions.
Topics: Algorithms; Computers; Data Collection; Digoxin; Drug-Related Side Effects and Adverse Reactions; Ge | 1988 |
[Patient documentation as the basis for the detection of drug side--effects--report of experiences of a combined analysis].
Topics: Aged; Analgesics; Antihypertensive Agents; Cardiac Glycosides; Drug-Related Side Effects and Adverse | 1987 |
[Side effects of various drugs acting on the eye].
Topics: Cardiac Glycosides; Chloroquine; Contraceptives, Oral; Cyproheptadine; Drug-Related Side Effects and | 1972 |
[Which drugs can cause glaucoma?].
Topics: Caffeine; Central Nervous System Stimulants; Drug-Related Side Effects and Adverse Reactions; Epinep | 1970 |
Potential dangers of common drug dosing regimens.
Topics: Circadian Rhythm; Computers; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse | 1974 |