Page last updated: 2024-10-22

theophylline and Adenoma, beta-Cell

theophylline has been researched along with Adenoma, beta-Cell in 8 studies

Research Excerpts

ExcerptRelevanceReference
"Glucagon-producing cell lines were established by fusing pancreatic islet cells of adult hamster and 6-thioguanine-resistant hamster insulinoma cells."3.67Establishment of glucagon-producing cells by cell hybridization. ( Kawaoi, A; Koyama, H; Kumae, S; Nakamura, M; Ono, J; Takaki, R; Yokogawa, Y, 1984)
"The cell line In-R1-G9 is one of the clones from the hamster insulinoma cell line, In-111-R1, and it produces glucagon."3.67Effect of phorbol esters on glucagon secretion from a glucagon-secreting clonal cell line. Synergistic effects of A23187 and theophylline. ( Kumae, S; Ono, J; Sato, Y; Takaki, R, 1986)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takaki, R2
Ono, J2
Yokogawa, Y1
Kumae, S2
Nakamura, M1
Koyama, H1
Kawaoi, A1
Sopwith, AM1
Hutton, JC1
Naber, SP1
Chick, WL1
Hales, CN1
Sjöholm, A1
Arkhammar, P2
Welsh, N1
Bokvist, K1
Rorsman, P2
Hallberg, A1
Nilsson, T1
Welsh, M1
Berggren, PO2
Ishihara, K1
Taniguchi, H1
Ejiri, K1
Baba, S1
Flatt, PR2
Swanston-Flatt, SK2
Powell, CJ1
Marks, V1
Abrahamsson, H1
Sato, Y1
Giroix, MH1
Blachier, F1
Sener, A1
Malaisse, WJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
TArgeting Type 1 Diabetes Using POLyamines (TADPOL): A Randomized, Double-Masked, Placebo-Controlled Phase 2 Study to Evaluate the Efficacy and Safety of Difluoromethylornithine (DFMO) to Preserve Insulin Production in Type 1 Diabetes[NCT05594563]Phase 270 participants (Anticipated)Interventional2023-03-14Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

8 other studies available for theophylline and Adenoma, beta-Cell

ArticleYear
Establishment of glucagon-producing cells by cell hybridization.
    Diabetes, 1984, Volume: 33, Issue:9

    Topics: Adenoma, Islet Cell; Animals; Cell Fusion; Cell Line; Cricetinae; Glucagon; Glucose; Histocytochemis

1984
Insulin secretion by a transplantable rat islet cell tumour.
    Diabetologia, 1981, Volume: 21, Issue:3

    Topics: Adenoma, Islet Cell; Animals; Colchicine; Epinephrine; Glucagon; Glucose; Insulin; Insulin Secretion

1981
Enhanced stimulus-secretion coupling in polyamine-depleted rat insulinoma cells. An effect involving increased cytoplasmic Ca2+, inositol phosphate generation, and phorbol ester sensitivity.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:4

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Carbachol; Cytoplasm; Diazoxide; DNA, Ne

1993
Effect of the cooling rate on insulin release from frozen-thawed In-111 cells.
    Diabetes research and clinical practice, 1991, Volume: 11, Issue:2

    Topics: Animals; Cell Line; Cold Temperature; Cricetinae; Freezing; Glucose; Insulin; Insulin Secretion; Ins

1991
Defective regulation of insulin release and transmembrane Ca2+ fluxes by human islet cell tumours.
    British journal of cancer, 1987, Volume: 56, Issue:4

    Topics: Adenoma, Islet Cell; Adolescent; Calcium; Female; Humans; Insulin; Insulin Secretion; Insulinoma; Io

1987
Measurements of membrane potential, transmembrane 45Ca fluxes, cytoplasmic free Ca2+ concentration and insulin release by transplantable rat insulinoma cells maintained in tissue culture.
    British journal of cancer, 1988, Volume: 58, Issue:1

    Topics: Adenoma, Islet Cell; Animals; Bucladesine; Calcium; Calcium Channel Blockers; Cytoplasm; Glucose; In

1988
Effect of phorbol esters on glucagon secretion from a glucagon-secreting clonal cell line. Synergistic effects of A23187 and theophylline.
    Diabetes research and clinical practice, 1986, Volume: 2, Issue:1

    Topics: Adenoma, Islet Cell; Animals; Calcimycin; Cell Line; Clone Cells; Cricetinae; Drug Synergism; Glucag

1986
Metabolic and secretory response of tumoral-insulin producing cells to D-fructose and D-galactose.
    Molecular and cellular biochemistry, 1987, Volume: 74, Issue:2

    Topics: Adenine Nucleotides; Adenoma, Islet Cell; Animals; Energy Metabolism; Fructose; Galactose; Glutamine

1987