theophylline has been researched along with Abnormalities, Drug-Induced in 22 studies
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Caffeine is a central nervous system stimulant that has come under increasing scrutiny due to its effects on the health and mental health of those who consume it." | 2.37 | Caffeine: implications of recent research for clinical practice. ( Wells, SJ, 1984) |
| " Addition of the intact MAS did not alter the developmental toxicity of 1-methyl- or 3-methylxanthine which were slightly more developmentally toxic on an equimolar basis than theophylline itself." | 1.29 | Evaluation of the developmental toxicity of theophylline, dimethyluric acid, and methylxanthine metabolites using Xenopus. ( Bantle, JA; Fort, DJ; Hull, MA; Propst, T; Stover, EL, 1996) |
| "30%) that did not produce overt maternal toxicity, but the adverse developmental effects in mice were observed at doses that caused reduced maternal water consumption and body weight gain." | 1.28 | The developmental toxicity of orally administered theophylline in rats and mice. ( George, JD; Kimmel, CA; Lindström, P; Marr, MC; Morrissey, RE; Price, CJ; Schwetz, BA, 1990) |
| "The Rai and Van Ryzin dose-response model proposed for teratology experiments has been characterized for its appropriateness and applicability in modeling the dichotomous response data from developmental toxicity studies." | 1.28 | Characterization of a developmental toxicity dose-response model. ( Faustman, EM; Kimmel, CA; Smith, WP; Wellington, DG, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (68.18) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stiefelhagen, P | 1 |
| KNOCHE, C | 1 |
| KOENIG, J | 1 |
| Gluck, JC | 1 |
| Gluck, PA | 1 |
| Osur, SL | 1 |
| Bruyere, HJ | 2 |
| Fallon, JF | 1 |
| Gilbert, EF | 3 |
| Wells, SJ | 1 |
| Nakatsuka, T | 1 |
| Hanada, S | 1 |
| Fujii, T | 2 |
| Tanaka, H | 1 |
| Nakazawa, K | 1 |
| Arima, M | 1 |
| Iwasaki, S | 1 |
| Nomura, T | 1 |
| Zenk, KE | 1 |
| Fort, DJ | 1 |
| Stover, EL | 1 |
| Propst, T | 1 |
| Hull, MA | 1 |
| Bantle, JA | 2 |
| Shibata, M | 1 |
| Wachi, M | 1 |
| Kawaguchi, M | 1 |
| Kojima, J | 1 |
| Onodera, K | 1 |
| Schatz, M | 1 |
| Ishikawa, S | 1 |
| Cheung, MO | 1 |
| Hodach, RJ | 1 |
| Lindström, P | 1 |
| Morrissey, RE | 1 |
| George, JD | 1 |
| Price, CJ | 1 |
| Marr, MC | 1 |
| Kimmel, CA | 2 |
| Schwetz, BA | 1 |
| Faustman, EM | 1 |
| Wellington, DG | 1 |
| Smith, WP | 1 |
| Dawson, DA | 1 |
| York, RG | 1 |
| Randall, JL | 1 |
| Scott, WJ | 1 |
| Matsuoka, R | 1 |
| Bruyers, H | 1 |
| Optiz, JM | 1 |
| Nelson, SR | 1 |
| Walaszek, EJ | 1 |
| Maren, TH | 1 |
| Ellison, AC | 1 |
| Nishimura, H | 1 |
6 reviews available for theophylline and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Asthma controller therapy during pregnancy.
Topics: Abnormalities, Drug-Induced; Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Ag | 2005 |
The management of asthma and rhinitis during pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Anti-Asthmati | 2005 |
Caffeine: implications of recent research for clinical practice.
Topics: Abnormalities, Drug-Induced; Affective Symptoms; Animals; Blood Pressure; Brain; Caffeine; Child; De | 1984 |
An overview of perinatal clinical pharmacology.
Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digo | 1981 |
The efficacy and safety of asthma medications during pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agent | 2001 |
Pharmacology of the central nervous system.
Topics: Abnormalities, Drug-Induced; Acetylcholine; Adrenocorticotropic Hormone; Amphetamine; Anger; Angiote | 1968 |
16 other studies available for theophylline and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[Pulmonary diseases in pregnancy. What drugs are permitted?].
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antitubercular Agents; | 2009 |
[ON THE PRENATAL TOXICITY OF DIPHENYLPYRALINE 8-CHLOROTHEOPHYLLINATE WITH REFERENCE TO EXPERIENCES WITH THALIDOMIDE AND CAFFEINE].
Topics: Abnormalities, Drug-Induced; Anti-Allergic Agents; Caffeine; Fetal Death; Histamine H1 Antagonists; | 1964 |
External malformations in chick embryos following concomitant administration of methylxanthines and beta-adrenomimetic agents: 1. Gross pathologic features.
Topics: Abnormalities, Drug-Induced; Adrenergic beta-Agonists; Animals; Caffeine; Chick Embryo; Dose-Respons | 1983 |
Potentiating effects of methylxanthines on teratogenicity of mitomycin C in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Caffeine; Drug Synergism; Female; | 1983 |
Caffeine and its dimethylxanthines and fetal cerebral development in rat.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Caffeine; Female; Fetus; Maternal-Fetal Exchange; Pregn | 1984 |
Comparative inhibiting effects of methylxanthines on urethan-induced tumors, malformations, and presumed somatic mutations in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Caffeine; DNA Repair; Lung Neoplasms; M | 1983 |
Evaluation of the developmental toxicity of theophylline, dimethyluric acid, and methylxanthine metabolites using Xenopus.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Nonmammalian; Embryonic and Fetal Development; Female; | 1996 |
Teratogenic and fetal toxicity following intravenous theophylline administration in pregnant rabbits is related to maternal drug plasma levels.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Bone and Bones; Dose-Response Relationship, Drug; | 2000 |
The effects of methylxanthines on catecholamine-stimulated and normal chick embryos.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Abnormalities, Drug-Induced; Animals; Aortic Aneurysm; Aortic A | 1977 |
The developmental toxicity of orally administered theophylline in rats and mice.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Cyclic AMP; Eating; Female; Fetal Resorp | 1990 |
Characterization of a developmental toxicity dose-response model.
Topics: Abnormalities, Drug-Induced; Animals; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Envi | 1989 |
Coadministration of methylxanthines and inhibitor compounds potentiates teratogenicity in Xenopus embryos.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cycloheximide; Cytarabine; Drug Synergism; Embryo, N | 1987 |
Teratogenicity of paraxanthine (1,7-dimethylxanthine) in C57BL/6J mice.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cleft Palate; Dose-Response Relationship, Drug; Fema | 1986 |
An aborted human fetus with truncus arteriosus communis--possible teratogenic effect of Tedral.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Drug Combinations; Embryo, Mammalian; Eph | 1985 |
The teratological effect of benzolamide, a new carbonic anhydrase inhibitor.
Topics: Abnormalities, Drug-Induced; Acid-Base Equilibrium; Animals; Carbonic Anhydrase Inhibitors; Female; | 1972 |
Teratogenic actions of some methylated xanthines in mice.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Fetus; Injections, Intraperitoneal; Male; Mi | 1969 |