theobromine has been researched along with Varicose Ulcer in 6 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Varicose Ulcer: Skin breakdown or ulceration in the drainage area of a VARICOSE VEIN, usually in the leg.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In an open field study, 70 patients with leg ulcers, some existing already for a long time, were treated with Pentoxifylline in addition to the hitherto applied local therapy." | 3.66 | [Trental forte in leg ulcer therapy. Result of a field study]. ( Schmidt-Modrow, G; Weitgasser, H, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weitgasser, H | 1 |
| Schmidt-Modrow, G | 1 |
| Colgan, MP | 1 |
| Dormandy, JA | 1 |
| Jones, PW | 1 |
| Schraibman, IG | 1 |
| Shanik, DG | 1 |
| Young, RA | 1 |
| Gajraj, H | 1 |
| Jopp-McKay, A | 1 |
| Stacey, MC | 1 |
| Angelides, NS | 1 |
| Weil von der Ahe, CA | 1 |
| Galbiati, G | 1 |
| Carnovali, M | 1 |
| Dvorkin, SB | 1 |
| Chernookiĭ, GP | 1 |
1 trial available for theobromine and Varicose Ulcer
| Article | Year |
|---|---|
Oxpentifylline treatment of venous ulcers of the leg.
Topics: Double-Blind Method; Female; Humans; Male; Pentoxifylline; Prognosis; Prospective Studies; Randomize | 1990 |
5 other studies available for theobromine and Varicose Ulcer
| Article | Year |
|---|---|
[Trental forte in leg ulcer therapy. Result of a field study].
Topics: Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Leg Ulcer; Male; Middle | 1982 |
Oxpentifylline treatment of venous leg ulcers.
Topics: Bandages; Humans; Pentoxifylline; Theobromine; Varicose Ulcer | 1990 |
Effect of oral pentoxifylline therapy on venous lower extremity ulcers due to deep venous incompetence.
Topics: Administration, Oral; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Pentoxifylline | 1989 |
[Usefulness of pentoxifylline in the therapy of venous and mixed dystrophic ulcers of the legs].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Drug Evaluation; Female; Humans; Male; Middle | 1987 |
[Conservative treatment of trophic leg ulcers with trental].
Topics: Adult; Aged; Chronic Disease; Drug Evaluation; Female; Humans; Male; Middle Aged; Pentoxifylline; Th | 1985 |