theobromine has been researched along with Shock, Septic in 6 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentoxifylline (POF) was found to possess high protecting potential in murine endotoxin shock." | 7.68 | Pentoxifylline increases survival in murine endotoxin shock and decreases formation of tumor necrosis factor. ( Schade, UF, 1990) |
| "Pentoxifylline (POF) was found to possess high protecting potential in murine endotoxin shock." | 3.68 | Pentoxifylline increases survival in murine endotoxin shock and decreases formation of tumor necrosis factor. ( Schade, UF, 1990) |
| "Pentoxifylline (Trental) is a well-known vasoactive drug with proven clinical efficacy in various circulatory disorders." | 2.38 | The effect of pentoxifylline in septic shock--new pharmacologic aspects of an established drug. ( Schade, UF; Schönharting, MM, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sugiura, Y | 1 |
| Kato, T | 1 |
| Goto, Y | 1 |
| Yamamoto, K | 1 |
| Aochi, O | 1 |
| Waxman, K | 1 |
| Schade, UF | 3 |
| von der Bosch, J | 1 |
| Schönharting, M | 1 |
| Schönharting, MM | 1 |
| Puranapanda, V | 1 |
| Hinshaw, LB | 1 |
| O'Rear, EA | 1 |
| Chang, AC | 1 |
| Whitsett, TL | 1 |
1 review available for theobromine and Shock, Septic
| Article | Year |
|---|---|
The effect of pentoxifylline in septic shock--new pharmacologic aspects of an established drug.
Topics: Animals; Disease Models, Animal; Mice; Pentoxifylline; Shock, Septic; Theobromine | 1989 |
5 other studies available for theobromine and Shock, Septic
| Article | Year |
|---|---|
[Experimental study on the effect of pentoxifylline on blood rheology and microcirculation--a study using an endotoxin shock model].
Topics: Animals; Blood Flow Velocity; Blood Viscosity; Disease Models, Animal; Microcirculation; Pentoxifyll | 1983 |
Pentoxifylline in septic shock.
Topics: Animals; Pentoxifylline; Shock, Septic; Swine; Theobromine | 1990 |
Pentoxifylline increases survival in murine endotoxin shock and decreases formation of tumor necrosis factor.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Galactosamine; Kinetics; Lipopolysacchari | 1990 |
Pentoxifylline increases survival of mice in endotoxic shock.
Topics: Animals; Epoprostenol; Female; Indomethacin; Leukopenia; Lipopolysaccharides; Mice; Pentoxifylline; | 1989 |
Erythrocyte deformability in canine septic shock and the efficacy of pentoxifylline and a leukotriene antagonist.
Topics: Acetophenones; Animals; Azoles; Dogs; Erythrocyte Deformability; Escherichia coli Infections; Female | 1987 |