Page last updated: 2024-11-05

theobromine and Parkinson Disease

theobromine has been researched along with Parkinson Disease in 4 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Janitschke, D1
Lauer, AA1
Bachmann, CM1
Grimm, HS1
Hartmann, T1
Grimm, MOW1
EHLERS, G1
Godwin-Austen, RB1
Twomey, JA1
Hanks, G1
Higgins, J1

Reviews

1 review available for theobromine and Parkinson Disease

ArticleYear
Methylxanthines and Neurodegenerative Diseases: An Update.
    Nutrients, 2021, Feb-28, Volume: 13, Issue:3

    Topics: Alzheimer Disease; Animals; Caffeine; Coffee; Humans; Multiple Sclerosis; Neurodegenerative Diseases

2021

Other Studies

3 other studies available for theobromine and Parkinson Disease

ArticleYear
[On the applicability of cosaldon in the treatment of cerebral sclerotic parkinsonism].
    Munchener medizinische Wochenschrift (1950), 1959, Aug-07, Volume: 101

    Topics: Drug Combinations; Niacin; Nicotinic Acids; Parkinson Disease; Parkinsonian Disorders; Theobromine;

1959
Oxpentifylline in Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 1980, Volume: 43, Issue:4

    Topics: Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle

1980
[Cosaldon opens blood-brain barrier].
    Zeitschrift fur Allgemeinmedizin, 1971, Sep-10, Volume: 47, Issue:25

    Topics: Blood-Brain Barrier; Drug Synergism; Humans; Intracranial Arteriosclerosis; Nicotinic Acids; Parkins

1971