theobromine has been researched along with Parkinson Disease in 4 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (75.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Authors | Studies |
---|---|
Janitschke, D | 1 |
Lauer, AA | 1 |
Bachmann, CM | 1 |
Grimm, HS | 1 |
Hartmann, T | 1 |
Grimm, MOW | 1 |
EHLERS, G | 1 |
Godwin-Austen, RB | 1 |
Twomey, JA | 1 |
Hanks, G | 1 |
Higgins, J | 1 |
1 review available for theobromine and Parkinson Disease
Article | Year |
---|---|
Methylxanthines and Neurodegenerative Diseases: An Update.
Topics: Alzheimer Disease; Animals; Caffeine; Coffee; Humans; Multiple Sclerosis; Neurodegenerative Diseases | 2021 |
3 other studies available for theobromine and Parkinson Disease
Article | Year |
---|---|
[On the applicability of cosaldon in the treatment of cerebral sclerotic parkinsonism].
Topics: Drug Combinations; Niacin; Nicotinic Acids; Parkinson Disease; Parkinsonian Disorders; Theobromine; | 1959 |
Oxpentifylline in Parkinson's disease.
Topics: Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle | 1980 |
[Cosaldon opens blood-brain barrier].
Topics: Blood-Brain Barrier; Drug Synergism; Humans; Intracranial Arteriosclerosis; Nicotinic Acids; Parkins | 1971 |