theobromine has been researched along with Nephrolithiasis in 3 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Nephrolithiasis: Formation of stones in the KIDNEY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the capacity of methylxanthines (caffeine, theophylline, theobromine and paraxanthine) to inhibit uric acid crystallization, and to evaluate their potential application in the treatment of uric acid nephrolithiasis." | 7.80 | Theobromine inhibits uric acid crystallization. A potential application in the treatment of uric acid nephrolithiasis. ( Costa-Bauza, A; Grases, F; Rodriguez, A, 2014) |
| "The combined consumption of citrate and theobromine may be a promising strategy for the prevention of UA kidney stones." | 5.34 | Comparison of Two Dietary Supplements for Treatment of Uric Acid Renal Lithiasis: Citrate vs. Citrate + Theobromine. ( Benejam, J; Calvó, P; Costa-Bauza, A; Grases, F; Hernandez, Y; Sanchis, P, 2020) |
| "To assess the capacity of methylxanthines (caffeine, theophylline, theobromine and paraxanthine) to inhibit uric acid crystallization, and to evaluate their potential application in the treatment of uric acid nephrolithiasis." | 3.80 | Theobromine inhibits uric acid crystallization. A potential application in the treatment of uric acid nephrolithiasis. ( Costa-Bauza, A; Grases, F; Rodriguez, A, 2014) |
| "Uric acid lithiasis accounts for about 10% of all types of renal lithiasis." | 1.91 | Efficacy of Theobromine and Its Metabolites in Reducing the Risk of Uric Acid Lithiasis. ( Calvó, P; Costa-Bauzá, A; Grases, F; Hernández, Y, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Costa-Bauzá, A | 3 |
| Calvó, P | 2 |
| Hernández, Y | 2 |
| Grases, F | 3 |
| Benejam, J | 1 |
| Sanchis, P | 1 |
| Rodriguez, A | 1 |
1 trial available for theobromine and Nephrolithiasis
| Article | Year |
|---|---|
Comparison of Two Dietary Supplements for Treatment of Uric Acid Renal Lithiasis: Citrate vs. Citrate + Theobromine.
Topics: Aged; Citric Acid; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Drug Combinations; | 2020 |
2 other studies available for theobromine and Nephrolithiasis
| Article | Year |
|---|---|
Efficacy of Theobromine and Its Metabolites in Reducing the Risk of Uric Acid Lithiasis.
Topics: Humans; Lithiasis; Nephrolithiasis; Pharmaceutical Preparations; Theobromine; Uric Acid | 2023 |
Theobromine inhibits uric acid crystallization. A potential application in the treatment of uric acid nephrolithiasis.
Topics: Caffeine; Crystallization; Humans; Microscopy, Electron, Scanning; Nephrolithiasis; Oxalates; Theobr | 2014 |