Page last updated: 2024-11-05

theobromine and Neoplasms

theobromine has been researched along with Neoplasms in 7 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Acetaldehyde formation was determined by GC-FID analysis in the head space of incubation mixtures."5.31Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects. ( Castro, GD; Castro, JA; Costantini, MH; Delgado de Layño, AM, 2001)
"Unfortunately, many types of cancers are extremely aggressive and untreatable since, in many cases, they are resistant to chemotherapy."2.82Natural products targeting into cancer hallmarks: An update on caffeine, theobromine, and (+)-catechin. ( Cadoná, FC; Dantas, RF; de Mello, GH; Silva-Jr, FP, 2022)
"Acetaldehyde formation was determined by GC-FID analysis in the head space of incubation mixtures."1.31Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects. ( Castro, GD; Castro, JA; Costantini, MH; Delgado de Layño, AM, 2001)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Cadoná, FC1
Dantas, RF1
de Mello, GH1
Silva-Jr, FP1
Kim, J2
Shim, J1
Lee, CY1
Lee, KW1
Lee, HJ1
Franco, R1
Osowski, A1
Pietrzak, M1
Wieczorek, Z1
Wieczorek, J1
Castro, GD1
Delgado de Layño, AM1
Costantini, MH1
Castro, JA1

Reviews

4 reviews available for theobromine and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Natural products targeting into cancer hallmarks: An update on caffeine, theobromine, and (+)-catechin.
    Critical reviews in food science and nutrition, 2022, Volume: 62, Issue:26

    Topics: Antioxidants; Biological Products; Caffeine; Catechin; Humans; Neoplasms; Theobromine

2022
Cocoa phytochemicals: recent advances in molecular mechanisms on health.
    Critical reviews in food science and nutrition, 2014, Volume: 54, Issue:11

    Topics: Animals; Biological Availability; Cacao; Caffeine; Cardiovascular Diseases; Diabetes Mellitus; Flavo

2014
[Coffee and cancer].
    Medicina clinica, 2008, Nov-08, Volume: 131, Issue:16

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Anticarcinogenic Agents; Caffeine; Cell Trans

2008

Other Studies

3 other studies available for theobromine and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Natural compounds in the human diet and their ability to bind mutagens prevents DNA-mutagen intercalation.
    Journal of toxicology and environmental health. Part A, 2010, Volume: 73, Issue:17-18

    Topics: Acridine Orange; Antineoplastic Agents; Biophysical Phenomena; Caffeine; Carcinogens; Chlorophyll; C

2010
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.
    Teratogenesis, carcinogenesis, and mutagenesis, 2001, Volume: 21, Issue:2

    Topics: Acetaldehyde; Alcohol Drinking; Allopurinol; Animals; Antimetabolites; Caffeine; Carcinogens; Chroma

2001