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theobromine and Myocardial Ischemia

theobromine has been researched along with Myocardial Ischemia in 5 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"Adenosine (100 microM) was administered to these neurons via their local arterial blood supply during or immediately after transient coronary artery occlusion."1.32Adenosine A1 receptor activation reduces myocardial reperfusion effects on intrinsic cardiac nervous system. ( Armour, JA; Arora, RC, 2003)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arora, RC1
Armour, JA1
Raschke, P1
Becker, BF1
Felix, SB3
Stangl, V3
Frank, TM2
Harms, C2
Berndt, T1
Kästner, R1
Baumann, G3
Frank, T1
Stangl, K2
Muss, J1
Buttke, K1
Schrör, K1

Other Studies

5 other studies available for theobromine and Myocardial Ischemia

ArticleYear
Adenosine A1 receptor activation reduces myocardial reperfusion effects on intrinsic cardiac nervous system.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:5

    Topics: Adenosine; Animals; Female; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Recepto

2003
Adenosine and PAF dependent mechanisms lead to myocardial reperfusion injury by neutrophils after brief ischaemia.
    Cardiovascular research, 1995, Volume: 29, Issue:4

    Topics: Adenosine; Animals; Azepines; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion

1995
Release of a stable cardiodepressant mediator after myocardial ischaemia during reperfusion.
    Cardiovascular research, 1997, Volume: 35, Issue:1

    Topics: Adenosine Deaminase; Adrenergic beta-Antagonists; Animals; Autacoids; Catalase; Depression, Chemical

1997
Cardiodepressant mediators are released after myocardial ischaemia: modulation by catecholamines and adenosine.
    Acta physiologica Scandinavica, 1999, Volume: 165, Issue:4

    Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Catecholamines; Chromatography, High Pressure Liqui

1999
Interaction of adenosine and prostacyclin in coronary flow regulation after myocardial ischemia.
    European journal of pharmacology, 1999, Jul-14, Volume: 377, Issue:1

    Topics: Adenosine; Animals; Cyclooxygenase Inhibitors; Drug Interactions; Epoprostenol; Guinea Pigs; Heart;

1999