theobromine has been researched along with Muscle Contraction in 21 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Recent studies have shown beneficial effects of an adenosine A(2A) receptor agonist in dt(sz) mutant hamsters, an animal model of paroxysmal dystonia, in which stress and consumption of coffee can precipitate dystonic attacks." | 7.71 | Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia. ( Hamann, M; Richter, A, 2001) |
| "Evaluate the potential inhibition of cough in a mouse model induced by sulfur dioxide gas of methanol and chloroform extracts of aerial parts of Chamaedorea tepejilote." | 3.74 | Evaluation of anti-tussive activity of Chamaedorea tepejilote. ( Pérez G, C; Pérez G, S; Ponce M, H; Ventura R, E; Zavala S, MA, 2008) |
| " Recent studies have shown beneficial effects of an adenosine A(2A) receptor agonist in dt(sz) mutant hamsters, an animal model of paroxysmal dystonia, in which stress and consumption of coffee can precipitate dystonic attacks." | 3.71 | Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia. ( Hamann, M; Richter, A, 2001) |
| "The role of adenosine in regulating glycogen breakdown during electrically induced muscle contractions was investigated in isolated rat hindquarters perfused with a standard medium either lacking or containing 100 microU/ml insulin and/or 1." | 3.69 | Adenosine exerts a glycogen-sparing action in contracting rat skeletal muscle. ( Hespel, P; Richter, EA; Vergauwen, L, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (42.86) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pérez G, C | 1 |
| Zavala S, MA | 1 |
| Ventura R, E | 1 |
| Pérez G, S | 1 |
| Ponce M, H | 1 |
| Diniz, C | 1 |
| Leal, S | 1 |
| Gonçalves, J | 1 |
| DAVID, I | 1 |
| Zizzo, MG | 1 |
| Mulè, F | 1 |
| Serio, R | 1 |
| Fredholm, BB | 1 |
| Huddart, H | 1 |
| Bayton, E | 1 |
| Shanklin, J | 1 |
| Matzky, R | 1 |
| Darius, H | 1 |
| Schrör, K | 1 |
| Coleman, AW | 1 |
| Coleman, JR | 1 |
| Chiang, PH | 1 |
| Wu, SN | 1 |
| Tsai, EM | 1 |
| Wu, CC | 1 |
| Shen, MR | 1 |
| Huang, CH | 1 |
| Chiang, CP | 1 |
| Orón, JD | 1 |
| Cortijo, J | 1 |
| Perpiñá, M | 1 |
| Morcillo, EJ | 1 |
| Hadjkaddour, K | 1 |
| Michel, A | 1 |
| Laurent, F | 1 |
| Boucard, M | 1 |
| Vergauwen, L | 1 |
| Richter, EA | 1 |
| Hespel, P | 1 |
| Lagente, V | 1 |
| Barlinski, J | 1 |
| Cano, E | 1 |
| Frossard, N | 1 |
| Coupar, IM | 1 |
| Tran, BL | 1 |
| Richter, A | 1 |
| Hamann, M | 1 |
| Fahim, M | 1 |
| Mustafa, SJ | 1 |
| Hudlická, O | 1 |
| Price, S | 1 |
| Alvarez, FJ | 1 |
| Carvajal, A | 1 |
| Velasco, A | 1 |
| Fleisch, JH | 1 |
| Titus, E | 1 |
| Blinks, JR | 1 |
| Olson, CB | 1 |
| Jewell, BR | 1 |
| Bravený, P | 1 |
| Cohen, Y | 1 |
| Lesne, M | 1 |
| Valette, G | 1 |
| Wepierre, J | 1 |
1 review available for theobromine and Muscle Contraction
| Article | Year |
|---|---|
Effects of methylxanthines on skeletal muscle and on respiration.
Topics: Animals; Caffeine; Histamine Release; Muscle Contraction; Muscles; Respiration; Theobromine; Theophy | 1984 |
1 trial available for theobromine and Muscle Contraction
| Article | Year |
|---|---|
Adenosine modulation of neurotransmission in penile erection.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Aged; Alprostadil; Animals; Antihypertensive Ag | 1994 |
19 other studies available for theobromine and Muscle Contraction
| Article | Year |
|---|---|
Evaluation of anti-tussive activity of Chamaedorea tepejilote.
Topics: Administration, Oral; Animals; Antitussive Agents; Arecaceae; Cough; Disease Models, Animal; Dose-Re | 2008 |
Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Epididymis; Immunohis | 2003 |
[Contractile action of methylxanthines].
Topics: Caffeine; Humans; Muscle Contraction; Theobromine; Theophylline; Xanthines | 1957 |
Inhibitory responses to exogenous adenosine in murine proximal and distal colon.
Topics: Adenosine; Animals; Colon; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; Mice, In | 2006 |
Influence of some common methylxanthines on contractile responses and calcium mobilization of ileal, vas deferens and bladder smooth muscle.
Topics: Animals; Caffeine; Calcium; Ileum; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Stra | 1983 |
The release of prostacyclin (PGI2) by pentoxifylline from human vascular tissue.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Epoprostenol; Humans; In Vitro Techniques; Mus | 1982 |
Characterization of the methylxanthine-induced propagated wave phenomenon in striated muscle.
Topics: Animals; Caffeine; Chick Embryo; Halothane; Histocytochemistry; Muscle Contraction; Muscles; Quinine | 1980 |
Effects of alkylxanthines on contractility of diaphragm fibres isolated from normal and sensitized guinea-pigs.
Topics: Adenosine; Animals; Bronchodilator Agents; Caffeine; Calcium; Culture Media; Dantrolene; Diaphragm; | 1993 |
Smooth muscle relaxant activity of A1- and A2-selective adenosine receptor agonists in guinea pig trachea: involvement of potassium channels.
Topics: Adenosine; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Glyburide; Guinea Pi | 1996 |
Adenosine exerts a glycogen-sparing action in contracting rat skeletal muscle.
Topics: Adenosine; Animals; Caffeine; Cyclic AMP; Drug Combinations; Glycogen; Glycogen Synthase; Male; Musc | 1997 |
Adenosine reduces airway excitatory non-cholinergic (e-NC) contraction through both A1 and A2 adenosine receptor activation in the guinea pig.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bronchi; Cholinergic Fibers; Dipyridamole; Do | 1997 |
Withdrawal and bidirectional cross-withdrawal responses in rats treated with adenosine agonists and morphine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Female; Injections, Subcuta | 2001 |
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; | 2001 |
Evidence for the presence of A(1) adenosine receptors in the aorta of spontaneously hypertensive rats.
Topics: Adenine; Adenosine; Animals; Aorta; Culture Techniques; Dose-Response Relationship, Drug; Endotheliu | 2001 |
Effects of torbafylline, pentoxifylline and buflomedil on vascularisation and fibre type of rat skeletal muscles subjected to limited blood supply.
Topics: Animals; Blood Pressure; Body Weight; Capillaries; In Vitro Techniques; Male; Muscle Contraction; Mu | 1990 |
Effect of aluminum chloride on ascending colon of the rat.
Topics: Acetylcholine; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Colon; Dose-Resp | 1985 |
The prevention of isoproterenol desensitization and isoproterenol reversal.
Topics: Aminophylline; Angiotensin II; Animals; Aorta; Bromine; Desensitization, Immunologic; Drug Interacti | 1972 |
Influence of caffeine and other methylxanthines on mechanical properties of isolated mammalian heart muscle. Evidence for a dual mechanism of action.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atropine; Caffeine; Calcium; Calcium Isotop | 1972 |
[Interaction between xanthines and noradrenaline- 3 H in the isolated rat heart].
Topics: Animals; Caffeine; Cardiac Output; Electrocardiography; Heart; Heart Rate; In Vitro Techniques; Male | 1970 |