theobromine has been researched along with Malaria in 4 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of malaria infection due to Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of orally-administered caffeine (CA: 10 mg/kg) to its primary metabolites (theobromine (TB), paraxanthine (PX) and theophylline (TH)) were studied in 5-week-old male Wistar rats (n = 5 for each treatment)." | 7.68 | Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever. ( Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA, 1993) |
| " The effects of malaria infection due to Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of orally-administered caffeine (CA: 10 mg/kg) to its primary metabolites (theobromine (TB), paraxanthine (PX) and theophylline (TH)) were studied in 5-week-old male Wistar rats (n = 5 for each treatment)." | 3.68 | Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever. ( Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Addai, FK | 1 |
| Okolie, EE | 1 |
| Adewunmi, AI | 1 |
| Enwonwu, CO | 1 |
| Kokwaro, GO | 1 |
| Szwandt, IS | 1 |
| Glazier, AP | 1 |
| Ward, SA | 1 |
| Edwards, G | 1 |
| Ogwan'g, R | 1 |
| Mwangi, J | 1 |
| Gachihi, G | 1 |
| Nwachukwu, A | 1 |
| Roberts, CR | 1 |
| Martin, SK | 1 |
4 other studies available for theobromine and Malaria
| Article | Year |
|---|---|
Natural cocoa as diet-mediated antimalarial prophylaxis.
Topics: Antioxidants; Cacao; Cell Membrane; Chemoprevention; Flavonoids; Humans; Malaria; Nitric Oxide; Phen | 2010 |
Antimalarial activity of inhibitors of ADP-ribosyl transferase against Plasmodium yoelii infection in mice. 1. Preliminary data.
Topics: Animals; Antimalarials; Benzamides; Chloroquine; Drug Evaluation, Preclinical; Malaria; Male; Mice; | 1982 |
Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever.
Topics: Administration, Oral; Animals; Caffeine; Endotoxins; Fever; Injections, Intravenous; Malaria; Male; | 1993 |
Use of pharmacological agents to implicate a role for phosphoinositide hydrolysis products in malaria gamete formation.
Topics: 2,3-Diphosphoglycerate; Animals; Caffeine; Calcium; Diglycerides; Diphosphoglyceric Acids; Gentamici | 1993 |