theobromine has been researched along with Lung Neoplasms in 9 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Lung Neoplasms: Tumors or cancer of the LUNG.
Excerpt | Relevance | Reference |
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"In the present study, we have examined the antimetastatic effect of flurbiprofen, a nonsteroidal antiinflammatory drug, on spontaneous metastases formation in mice bearing Lewis lung carcinoma and these results were compared with effects of other inhibitors of platelet function (mopidamole, dipyridamole, pentoxifylline)." | 3.67 | Antimetastatic effect of flurbiprofen and other platelet aggregation inhibitors. ( Grimová, J; Kacerovská, H; Mamytbeková, A; Rezábek, K; Svobodová, J, 1986) |
"Pentoxifylline (Trental), a phosphodiesterase inhibitor with platelet aggregation inhibitory effect, was shown to decrease spontaneous metastases in a Wilms' tumor model in Furth-Wistar rats and in neuroblastoma C1300 in A/J mice." | 3.66 | Studies on platelet aggregation inhibitors in vivo. VIII. Effect of pentoxifylline on spontaneous tumor metastasis. ( Ambrus, JL; Cohen, H; Gastpar, H; Gordon, S; Murphy, GP; Sciandra, J; Williams, P; Witul, M, 1979) |
"Theophylline- and caffeine-treated B16-F10 cells exhibited low adhesion to laminin/collagen type IV and reduced invasion through Matrigel in an in vitro assay." | 1.30 | Inhibition of melanoma pulmonary metastasis by methylxanthines due to decreased invasion and proliferation. ( Abbruzzese, A; Autuori-Pezzoli, V; Beninati, S; Cardinali, M; Kleinman, HK; Lentini, A; Mattioli, P; Nicolini, L; Pietrini, A, 1998) |
" In the present experiment pentoxifylline appears to be a highly effective platelet aggregation inhibitor: a dose-response curve is apparent in monkey between 6 and 24 mg/kg i." | 1.26 | Effect of phosphodiesterase inhibitors on platelet aggregation and tumor metastasis. ( Ambrus, CM; Ambrus, JL; Gastpar, H, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (44.44) | 18.7374 |
1990's | 4 (44.44) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (11.11) | 2.80 |
Authors | Studies |
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Elkaeed, EB | 1 |
Yousef, RG | 1 |
Elkady, H | 1 |
Alsfouk, AA | 1 |
Husein, DZ | 1 |
Ibrahim, IM | 1 |
Metwaly, AM | 1 |
Eissa, IH | 1 |
Ambrus, JL | 2 |
Ambrus, CM | 1 |
Gastpar, H | 2 |
Nomura, T | 1 |
Gil, M | 1 |
Skopińska-Rózewska, E | 2 |
Radomska, D | 1 |
Demkow, U | 2 |
Skurzak, H | 1 |
Rochowska, M | 1 |
Beuth, J | 1 |
Roszkowski, K | 1 |
Sommer, E | 1 |
Chorostowska-Wynimko, J | 1 |
Bałan, B | 1 |
Rózycka, B | 1 |
Barcz, E | 1 |
Filewska, M | 1 |
Mlekodaj, S | 1 |
Rudziński, P | 1 |
Seweryniak, W | 1 |
Caban, P | 1 |
Kupis, W | 1 |
Bogdan, J | 1 |
Usiekniewicz, P | 1 |
Gatarek, J | 1 |
Langfort, R | 1 |
Lentini, A | 1 |
Kleinman, HK | 1 |
Mattioli, P | 1 |
Autuori-Pezzoli, V | 1 |
Nicolini, L | 1 |
Pietrini, A | 1 |
Abbruzzese, A | 1 |
Cardinali, M | 1 |
Beninati, S | 1 |
Gordon, S | 1 |
Witul, M | 1 |
Cohen, H | 1 |
Sciandra, J | 1 |
Williams, P | 1 |
Murphy, GP | 1 |
Dezube, BJ | 1 |
Fridovich-Keil, JL | 1 |
Bouvard, I | 1 |
Lange, RF | 1 |
Pardee, AB | 1 |
Mamytbeková, A | 1 |
Rezábek, K | 1 |
Kacerovská, H | 1 |
Grimová, J | 1 |
Svobodová, J | 1 |
9 other studies available for theobromine and Lung Neoplasms
Article | Year |
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New Anticancer Theobromine Derivative Targeting EGFR
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; ErbB | 2022 |
Effect of phosphodiesterase inhibitors on platelet aggregation and tumor metastasis.
Topics: Adenocarcinoma; Adenosine Diphosphate; Animals; Carcinoma, Ehrlich Tumor; Female; Head and Neck Neop | 1981 |
Comparative inhibiting effects of methylxanthines on urethan-induced tumors, malformations, and presumed somatic mutations in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Caffeine; DNA Repair; Lung Neoplasms; M | 1983 |
Effect of purinergic receptor antagonists suramin and theobromine on tumor-induced angiogenesis in BALB/c mice.
Topics: Animals; Carcinoma; Injections, Subcutaneous; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neopl | 1993 |
Screening of angiogenesis inhibitors by modified tumor-induced angiogenesis (TIA) test in lung cancer.
Topics: Adenocarcinoma; Aged; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Drug Scr | 1997 |
Inhibition of melanoma pulmonary metastasis by methylxanthines due to decreased invasion and proliferation.
Topics: Animals; Caffeine; Cell Adhesion; Cell Division; Collagen; Laminin; Lung Neoplasms; Male; Melanins; | 1998 |
Studies on platelet aggregation inhibitors in vivo. VIII. Effect of pentoxifylline on spontaneous tumor metastasis.
Topics: Adenocarcinoma; Animals; Lung Neoplasms; Male; Mice; Mice, Inbred A; Mice, Inbred BALB C; Neoplasm M | 1979 |
Pentoxifylline and wellbeing in patients with cancer.
Topics: Adult; Breast Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Humans; Lung Neoplas | 1990 |
Antimetastatic effect of flurbiprofen and other platelet aggregation inhibitors.
Topics: Animals; Antineoplastic Agents; Dipyridamole; Flurbiprofen; Lung Neoplasms; Male; Mice; Mice, Inbred | 1986 |