Page last updated: 2024-11-05

theobromine and Ischemic Attack, Transient

theobromine has been researched along with Ischemic Attack, Transient in 14 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Research Excerpts

ExcerptRelevanceReference
"Transient global cerebral ischemia (tGCI) is a cerebrovascular disorder characterized by a brief decline in blood flow, neurological deficits, and is often predictive of stroke."5.62Neuroprotective effects of theobromine in transient global cerebral ischemia-reperfusion rat model. ( Bhat, JA; Gupta, S; Kumar, M, 2021)
"Pentoxifylline is a drug known to increase red cell deformability, thus allowing the 7- to 8-micrometers diameter red cell to flow through the narrowest capillaries of 3-5 micrometers diameter."2.36Pentoxifylline and cerebrovascular diseases. ( George, C; Marcel, GA, 1983)
"Transient global cerebral ischemia (tGCI) is a cerebrovascular disorder characterized by a brief decline in blood flow, neurological deficits, and is often predictive of stroke."1.62Neuroprotective effects of theobromine in transient global cerebral ischemia-reperfusion rat model. ( Bhat, JA; Gupta, S; Kumar, M, 2021)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199013 (92.86)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Bhat, JA1
Gupta, S1
Kumar, M1
Herskovits, E4
Vazquez, A3
Famulari, A4
Smud, R2
Tamaroff, L4
Fraiman, H4
Gonzalez, AM3
Vila, J4
Matera, V3
Warlow, C1
Peto, R1
Gawel, MJ1
Steiner, TJ1
Rose, FC1
Marcel, GA1
George, C1
Gonzáles, AM1
Shtok, VN1
Fedorova, NV1
Gadanova, IV1
Chen, HB1
Gerzić, Z1
Dukić, V1
Milicević, M1
Sen, S1
Chakravarty, A1
Vzquez, A1
Dominguez, R2
Benjamin, V1
Bluhm, RE1
Molnar, J1
Cohen, MM1
Hartmann, A1
Tsuda, Y1

Reviews

1 review available for theobromine and Ischemic Attack, Transient

ArticleYear
Pentoxifylline and cerebrovascular diseases.
    European neurology, 1983, Volume: 22 Suppl 1

    Topics: Animals; Blood Viscosity; Brain Edema; Cerebrovascular Circulation; Cerebrovascular Disorders; Dogs;

1983

Trials

6 trials available for theobromine and Ischemic Attack, Transient

ArticleYear
Randomised trial of pentoxifylline versus acetylsalicylic acid plus dipyridamole in preventing transient ischaemic attacks.
    Lancet (London, England), 1981, May-02, Volume: 1, Issue:8227

    Topics: Aspirin; Clinical Trials as Topic; Dipyridamole; Drug Therapy, Combination; Female; Follow-Up Studie

1981
A randomized clinical trial of pentoxifylline and antiaggregants in recent transient ischemic attacks (TIA). A one year follow-up.
    La Ricerca in clinica e in laboratorio, 1981, Volume: 11 Suppl 1

    Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Dipyridamole; Female; Follow-Up Studies; Humans; Isc

1981
Clinical experience with pentoxifylline in occlusive cerebrovascular disorders.
    Angiology, 1977, Volume: 28, Issue:5

    Topics: Adult; Cerebrovascular Disorders; Female; Hemiplegia; Humans; Ischemic Attack, Transient; Male; Moto

1977
Comparative study of pentoxifylline vs antiaggregants in patients with transient ischaemic attacks.
    Acta neurologica Scandinavica. Supplementum, 1989, Volume: 127

    Topics: Aged; Aspirin; Dipyridamole; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Pentoxif

1989
A controlled study on the effect of pentoxifylline and an ergot alkaloid derivative on regional cerebral blood flow in patients with chronic cerebrovascular disease.
    Angiology, 1988, Volume: 39, Issue:5

    Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Clinical Trials as Topic; E

1988
Preventive treatment of cerebral transient ischemia: comparative randomized trial of pentoxifylline versus conventional antiaggregants.
    European neurology, 1985, Volume: 24, Issue:1

    Topics: Aged; Aspirin; Clinical Trials as Topic; Dipyridamole; Drug Combinations; Female; Humans; Ischemic A

1985

Other Studies

7 other studies available for theobromine and Ischemic Attack, Transient

ArticleYear
Neuroprotective effects of theobromine in transient global cerebral ischemia-reperfusion rat model.
    Biochemical and biophysical research communications, 2021, 09-24, Volume: 571

    Topics: Administration, Oral; Animals; Brain Ischemia; Disease Models, Animal; Female; Glutathione; Ischemic

2021
Pentoxifylline for transient ischaemic attacks.
    Lancet (London, England), 1981, May-16, Volume: 1, Issue:8229

    Topics: Humans; Ischemic Attack, Transient; Pentoxifylline; Theobromine

1981
Pentoxifylline for prevention of transient ischaemic attacks.
    Lancet (London, England), 1981, Jun-06, Volume: 1, Issue:8232

    Topics: Humans; Ischemic Attack, Transient; Pentoxifylline; Theobromine

1981
[Clinical study of the cerebrovascular action of pentoxifylline].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:1

    Topics: Acute Disease; Adult; Arteriosclerosis; Brain Ischemia; Cerebrovascular Disorders; Chronic Disease;

1982
[A preliminary report of treatment of transient cerebral ischemic attacks with BL 191 (author's transl)].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1980, Volume: 13, Issue:2

    Topics: Aged; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Pentoxifylline; Theobromine; Va

1980
[Drug therapy of chronic tissue ischemia with improvement of microcirculation].
    Acta chirurgica Iugoslavica, 1978, Volume: 25, Issue:1

    Topics: Adult; Blood Vessel Prosthesis; Chronic Disease; Extremities; Humans; Ischemia; Ischemic Attack, Tra

1978
The effect of pentoxifylline on the energy metabolism of ischemic gerbil brain.
    Clinical neuropharmacology, 1985, Volume: 8, Issue:3

    Topics: Adenosine Triphosphate; Animals; Brain; Electron Transport Complex IV; Energy Metabolism; Gerbillina

1985