Page last updated: 2024-11-05

theobromine and Intraocular Pressure

theobromine has been researched along with Intraocular Pressure in 3 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"The effects of single or multiple topical doses of the relatively selective A1 adenosine receptor agonists (R)-phenylisopropyladenosine (R-PIA) and N6-cyclohexyladenosine (CHA) on intraocular pressure (IOP), aqueous humor flow (AHF) and outflow facility were investigated in ocular normotensive cynomolgus monkeys."7.69Effects of adenosine agonists on intraocular pressure and aqueous humor dynamics in cynomolgus monkeys. ( Crosson, CE; Gabelt, BT; Kaufman, PL; Tian, B, 1997)
"The effects of single or multiple topical doses of the relatively selective A1 adenosine receptor agonists (R)-phenylisopropyladenosine (R-PIA) and N6-cyclohexyladenosine (CHA) on intraocular pressure (IOP), aqueous humor flow (AHF) and outflow facility were investigated in ocular normotensive cynomolgus monkeys."3.69Effects of adenosine agonists on intraocular pressure and aqueous humor dynamics in cynomolgus monkeys. ( Crosson, CE; Gabelt, BT; Kaufman, PL; Tian, B, 1997)
"Adenosine is an autacoid released by all cells."1.30Contributions of adenosine receptor activation to the ocular actions of epinephrine. ( Crosson, CE; Petrovich, M, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Illgner, P1
Marx-Heep, I1
Tian, B1
Gabelt, BT1
Crosson, CE2
Kaufman, PL1
Petrovich, M1

Trials

1 trial available for theobromine and Intraocular Pressure

ArticleYear
[Therapeutic experiences in circulatory disorders of the eye. Results of a multicentric study].
    Die Medizinische Welt, 1983, Jan-07, Volume: 34, Issue:1

    Topics: Adult; Aged; Clinical Trials as Topic; Drug Combinations; Female; Humans; Intraocular Pressure; Male

1983

Other Studies

2 other studies available for theobromine and Intraocular Pressure

ArticleYear
Effects of adenosine agonists on intraocular pressure and aqueous humor dynamics in cynomolgus monkeys.
    Experimental eye research, 1997, Volume: 64, Issue:6

    Topics: Adenosine; Administration, Topical; Animals; Aqueous Humor; Drug Administration Schedule; Intraocula

1997
Contributions of adenosine receptor activation to the ocular actions of epinephrine.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:9

    Topics: Adenosine; Adrenergic Agonists; Animals; Aqueous Humor; Epinephrine; Inosine; Intraocular Pressure;

1999