theobromine has been researched along with Innate Inflammatory Response in 10 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Theobromine reduces adipogenesis and proinflammatory cytokines; these data suggest its potential therapeutic effect for treating obesity by control of macrophages infiltration in adipose tissue and inflammation." | 7.91 | Inflammatory Microenvironment and Adipogenic Differentiation in Obesity: The Inhibitory Effect of Theobromine in a Model of Human Obesity In Vitro. ( Bonmassar, E; Fuggetta, MP; Ravagnan, G; Villivà, C; Zonfrillo, M, 2019) |
| " Adenosine levels in sites of inflammation were shown to increase and exhibit immunoregulatory effects." | 7.73 | Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation. ( Chaimovitz, C; Douvdevani, A; Mazar, J; Nakav, S; Rogachev, B; Ziv, NY; Zlotnik, M, 2006) |
| "Theobromine reduces adipogenesis and proinflammatory cytokines; these data suggest its potential therapeutic effect for treating obesity by control of macrophages infiltration in adipose tissue and inflammation." | 3.91 | Inflammatory Microenvironment and Adipogenic Differentiation in Obesity: The Inhibitory Effect of Theobromine in a Model of Human Obesity In Vitro. ( Bonmassar, E; Fuggetta, MP; Ravagnan, G; Villivà, C; Zonfrillo, M, 2019) |
| " Adenosine levels in sites of inflammation were shown to increase and exhibit immunoregulatory effects." | 3.73 | Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation. ( Chaimovitz, C; Douvdevani, A; Mazar, J; Nakav, S; Rogachev, B; Ziv, NY; Zlotnik, M, 2006) |
| "The effect of spinal adenosine receptor ligation on peripheral leukocyte accumulation was studied in two rat models of inflammation." | 3.69 | Spinal cord adenosine receptor stimulation in rats inhibits peripheral neutrophil accumulation. The role of N-methyl-D-aspartate receptors. ( Bong, GW; Firestein, GS; Rosengren, S, 1996) |
| "Ziprasidone (ZIP) is an effective antipsychotic with low side effects than other second-generation antipsychotics." | 1.51 | The Influence of a Xanthine-Catechin Chemical Matrix on in vitro Macrophage-Activation Triggered by Antipsychotic Ziprasidone. ( Azzolin, VF; Barbisan, F; da Cruz Jung, IE; da Cruz, IBM; da Cunha, BSN; do Prado-Lima, PA; Duarte, MMMF; Duarte, T; Ribeiro, EE; Turra, BO, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duarte, T | 1 |
| Barbisan, F | 1 |
| da Cunha, BSN | 1 |
| Azzolin, VF | 1 |
| Turra, BO | 1 |
| Duarte, MMMF | 1 |
| da Cruz Jung, IE | 1 |
| Ribeiro, EE | 1 |
| do Prado-Lima, PA | 1 |
| da Cruz, IBM | 2 |
| Fuggetta, MP | 1 |
| Zonfrillo, M | 1 |
| Villivà, C | 1 |
| Bonmassar, E | 1 |
| Ravagnan, G | 1 |
| Ruchel, JB | 1 |
| Bernardes, VM | 1 |
| Braun, JBS | 1 |
| Manzoni, AG | 1 |
| Passos, DF | 1 |
| Castilhos, LG | 1 |
| Abdalla, FH | 1 |
| de Oliveira, JS | 1 |
| de Andrade, CM | 1 |
| Casali, EA | 1 |
| Leal, DBR | 1 |
| Rogachev, B | 1 |
| Ziv, NY | 1 |
| Mazar, J | 1 |
| Nakav, S | 1 |
| Chaimovitz, C | 1 |
| Zlotnik, M | 1 |
| Douvdevani, A | 1 |
| Goecke, IA | 1 |
| Alvarez, C | 1 |
| Henríquez, J | 1 |
| Salas, K | 1 |
| Molina, ML | 1 |
| Ferreira, A | 1 |
| Gatica, H | 1 |
| Cronstein, BN | 4 |
| Naime, D | 2 |
| Ostad, E | 2 |
| Bong, GW | 1 |
| Rosengren, S | 1 |
| Firestein, GS | 1 |
| Montesinos, MC | 2 |
| Weissmann, G | 2 |
10 other studies available for theobromine and Innate Inflammatory Response
| Article | Year |
|---|---|
The Influence of a Xanthine-Catechin Chemical Matrix on in vitro Macrophage-Activation Triggered by Antipsychotic Ziprasidone.
Topics: Animals; Antipsychotic Agents; Caffeine; Catechin; Cell Proliferation; Complex Mixtures; Inflammatio | 2019 |
Inflammatory Microenvironment and Adipogenic Differentiation in Obesity: The Inhibitory Effect of Theobromine in a Model of Human Obesity In Vitro.
Topics: Adipocytes; Adipogenesis; Cell Cycle; Cell Differentiation; Cell Line; Cell Line, Tumor; Cytokines; | 2019 |
Lipotoxicity-associated inflammation is prevented by guarana (
Topics: Adenosine; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Caffeine; Disease Models, Anim | 2021 |
Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Ant | 2006 |
Methotrexate regulates the expression of glucocorticoid receptor alpha and beta isoforms in normal human peripheral mononuclear cells and human lymphocyte cell lines in vitro.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Asthma; Autoimmune Diseases; Drug Synergism; Gene Expr | 2007 |
The antiinflammatory effects of methotrexate are mediated by adenosine.
Topics: Acyltransferases; Adenosine; Adenosine Deaminase; Aminoimidazole Carboxamide; Animals; Anti-Inflamma | 1994 |
The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.
Topics: Adenosine; Adenosine Deaminase; Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents, Non-S | 1993 |
Spinal cord adenosine receptor stimulation in rats inhibits peripheral neutrophil accumulation. The role of N-methyl-D-aspartate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anti-In | 1996 |
Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NFkappaB.
Topics: Adenosine Deaminase; Animals; Aspirin; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Female; Gluc | 1999 |
Sites of action for future therapy: an adenosine-dependent mechanism by which aspirin retains its antiinflammatory activity in cyclooxygenase-2 and NFkappaB knockout mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Inflammation; | 1999 |