theobromine has been researched along with Infections, Plasmodium in 4 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of malaria infection due to Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of orally-administered caffeine (CA: 10 mg/kg) to its primary metabolites (theobromine (TB), paraxanthine (PX) and theophylline (TH)) were studied in 5-week-old male Wistar rats (n = 5 for each treatment)." | 7.68 | Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever. ( Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA, 1993) |
| " The effects of malaria infection due to Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of orally-administered caffeine (CA: 10 mg/kg) to its primary metabolites (theobromine (TB), paraxanthine (PX) and theophylline (TH)) were studied in 5-week-old male Wistar rats (n = 5 for each treatment)." | 3.68 | Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever. ( Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Addai, FK | 1 |
| Okolie, EE | 1 |
| Adewunmi, AI | 1 |
| Enwonwu, CO | 1 |
| Kokwaro, GO | 1 |
| Szwandt, IS | 1 |
| Glazier, AP | 1 |
| Ward, SA | 1 |
| Edwards, G | 1 |
| Ogwan'g, R | 1 |
| Mwangi, J | 1 |
| Gachihi, G | 1 |
| Nwachukwu, A | 1 |
| Roberts, CR | 1 |
| Martin, SK | 1 |
4 other studies available for theobromine and Infections, Plasmodium
| Article | Year |
|---|---|
Natural cocoa as diet-mediated antimalarial prophylaxis.
Topics: Antioxidants; Cacao; Cell Membrane; Chemoprevention; Flavonoids; Humans; Malaria; Nitric Oxide; Phen | 2010 |
Antimalarial activity of inhibitors of ADP-ribosyl transferase against Plasmodium yoelii infection in mice. 1. Preliminary data.
Topics: Animals; Antimalarials; Benzamides; Chloroquine; Drug Evaluation, Preclinical; Malaria; Male; Mice; | 1982 |
Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever.
Topics: Administration, Oral; Animals; Caffeine; Endotoxins; Fever; Injections, Intravenous; Malaria; Male; | 1993 |
Use of pharmacological agents to implicate a role for phosphoinositide hydrolysis products in malaria gamete formation.
Topics: 2,3-Diphosphoglycerate; Animals; Caffeine; Calcium; Diglycerides; Diphosphoglyceric Acids; Gentamici | 1993 |