theobromine has been researched along with Hypoxia in 10 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We tested the hypotheses that 1) perinatal hypoglycemia impairs cerebrovascular responses to hypoxia and 2) a reduced vascular smooth muscle sensitivity to adenosine accounts for this impairment." | 7.69 | Hypoglycemia selectively abolishes hypoxic reactivity of pial arterioles in piglets: role of adenosine. ( Gidday, JM; Gonzales, ER; Park, TS; Shah, AR, 1995) |
| "The effects of pentoxifylline on pulmonary hemodynamics were studied in anesthetized dogs during acute alveolar hypoxia." | 7.67 | Effects of pentoxifylline on pulmonary hemodynamics during acute hypoxia in anesthetized dogs. ( Chick, TW; Doyle, MP; Icenogle, MV; Loeppky, JA; Riedel, CE; Scotto, P; Sikes, CW; Wood, SC, 1988) |
| " We tested the hypotheses that 1) perinatal hypoglycemia impairs cerebrovascular responses to hypoxia and 2) a reduced vascular smooth muscle sensitivity to adenosine accounts for this impairment." | 3.69 | Hypoglycemia selectively abolishes hypoxic reactivity of pial arterioles in piglets: role of adenosine. ( Gidday, JM; Gonzales, ER; Park, TS; Shah, AR, 1995) |
| "In the present study, we have investigated the possible role of adenosine in the hypoxia-mediated increase in adenosine 3',5'-cyclic monophosphate (cAMP) in the carotid body." | 3.69 | cAMP production in rabbit carotid body: role of adenosine. ( Chen, J; Dinger, B; Fidone, SJ, 1997) |
| "The effects of pentoxifylline on pulmonary hemodynamics were studied in anesthetized dogs during acute alveolar hypoxia." | 3.67 | Effects of pentoxifylline on pulmonary hemodynamics during acute hypoxia in anesthetized dogs. ( Chick, TW; Doyle, MP; Icenogle, MV; Loeppky, JA; Riedel, CE; Scotto, P; Sikes, CW; Wood, SC, 1988) |
| "Aminophylline was equally effective and selective in lowering PVR but not SVR during hypoxia." | 1.27 | Attenuation of pulmonary and systemic vasoconstriction with pentoxifylline and aminophylline. ( Hakim, TS; Petrella, J, 1988) |
| "Pentoxifylline (Pent) is a xanthine known to improve erythrocyte deformability and thought to have little effect on smooth muscle tone." | 1.27 | Reversal of pulmonary hypoxic vasoconstriction with pentoxifylline and aminophylline in isolated lungs. ( Hakim, TS, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| REICHERTZ, P | 1 |
| Palareti, G | 1 |
| Coccheri, S | 1 |
| Poggi, M | 1 |
| Tricarico, MG | 1 |
| Magelli, M | 1 |
| Cavazzuti, F | 1 |
| Steen, PA | 1 |
| Michenfelder, JD | 1 |
| Park, TS | 1 |
| Gonzales, ER | 1 |
| Shah, AR | 1 |
| Gidday, JM | 1 |
| Chen, J | 1 |
| Dinger, B | 1 |
| Fidone, SJ | 1 |
| Stefanovich, V | 1 |
| John, JP | 1 |
| Hershenson, MB | 1 |
| Schena, JA | 1 |
| Lozano, PA | 1 |
| Jacobson, MJ | 1 |
| Crone, RK | 1 |
| Hakim, TS | 2 |
| Petrella, J | 1 |
| Chick, TW | 1 |
| Scotto, P | 1 |
| Icenogle, MV | 1 |
| Sikes, CW | 1 |
| Doyle, MP | 1 |
| Riedel, CE | 1 |
| Wood, SC | 1 |
| Loeppky, JA | 1 |
10 other studies available for theobromine and Hypoxia
| Article | Year |
|---|---|
[THE EFFECT OF 7-(2-HYDROXY-3-(N-2-HYDROXYETHYL-N-METHYLAMINO)-PROPYL-THEOPHYLLINE NICOTINATE AND OTHER PURINE BODIES ON THE RESPIRATION AND ELECTROCARDIOGRAM OF GUINEA PIGS AND RATS IN HISTOTOXIC OXYGEN DEFICIENCY].
Topics: Cyanides; Electrocardiography; Guinea Pigs; Hypoxia; Niacin; Nicotinic Acids; Oxygen; Pharmacology; | 1963 |
Changes in the rheologic properties of blood after a high altitude expedition.
Topics: Adult; Altitude Sickness; Blood Circulation; Blood Platelets; Blood Viscosity; Erythrocytes; Humans; | 1984 |
Pentoxifylline does not protect mice against hypoxia.
Topics: Animals; Cerebrovascular Circulation; Disease Models, Animal; Energy Metabolism; Hypoxia; Mice; Mice | 1981 |
Hypoglycemia selectively abolishes hypoxic reactivity of pial arterioles in piglets: role of adenosine.
Topics: Adenosine; Animals; Animals, Newborn; Arterioles; Hemodynamics; Hypercapnia; Hypoglycemia; Hypoxia; | 1995 |
cAMP production in rabbit carotid body: role of adenosine.
Topics: Adenosine; Animals; Carotid Body; Cyclic AMP; Dipyridamole; Hypoxia; In Vitro Techniques; Phenethyla | 1997 |
Influence of pentifylline on brain metabolism of normal and anoxic rats.
Topics: Adenine Nucleotides; Animals; Brain; Carbohydrate Metabolism; Creatine; Female; Hypoxia; Rats; Theob | 1978 |
Effect of pentoxiphylline on oxygen transport during hypothermia.
Topics: Animals; Biological Availability; Biological Transport; Blood Viscosity; Dogs; Hypothermia; Hypoxia; | 1989 |
Attenuation of pulmonary and systemic vasoconstriction with pentoxifylline and aminophylline.
Topics: Aminophylline; Angiotensin II; Animals; Dogs; Hemodynamics; Hypoxia; Lung; Pentoxifylline; Swine; Th | 1988 |
Effects of pentoxifylline on pulmonary hemodynamics during acute hypoxia in anesthetized dogs.
Topics: Acute Disease; Animals; Blood Pressure; Blood Viscosity; Cardiac Output; Dogs; Erythrocyte Deformabi | 1988 |
Reversal of pulmonary hypoxic vasoconstriction with pentoxifylline and aminophylline in isolated lungs.
Topics: Aminophylline; Animals; Blood Gas Analysis; Blood Pressure; Female; Hypoxia; In Vitro Techniques; Lu | 1988 |