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theobromine and Hypoxia

theobromine has been researched along with Hypoxia in 10 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
" We tested the hypotheses that 1) perinatal hypoglycemia impairs cerebrovascular responses to hypoxia and 2) a reduced vascular smooth muscle sensitivity to adenosine accounts for this impairment."7.69Hypoglycemia selectively abolishes hypoxic reactivity of pial arterioles in piglets: role of adenosine. ( Gidday, JM; Gonzales, ER; Park, TS; Shah, AR, 1995)
"The effects of pentoxifylline on pulmonary hemodynamics were studied in anesthetized dogs during acute alveolar hypoxia."7.67Effects of pentoxifylline on pulmonary hemodynamics during acute hypoxia in anesthetized dogs. ( Chick, TW; Doyle, MP; Icenogle, MV; Loeppky, JA; Riedel, CE; Scotto, P; Sikes, CW; Wood, SC, 1988)
" We tested the hypotheses that 1) perinatal hypoglycemia impairs cerebrovascular responses to hypoxia and 2) a reduced vascular smooth muscle sensitivity to adenosine accounts for this impairment."3.69Hypoglycemia selectively abolishes hypoxic reactivity of pial arterioles in piglets: role of adenosine. ( Gidday, JM; Gonzales, ER; Park, TS; Shah, AR, 1995)
"In the present study, we have investigated the possible role of adenosine in the hypoxia-mediated increase in adenosine 3',5'-cyclic monophosphate (cAMP) in the carotid body."3.69cAMP production in rabbit carotid body: role of adenosine. ( Chen, J; Dinger, B; Fidone, SJ, 1997)
"The effects of pentoxifylline on pulmonary hemodynamics were studied in anesthetized dogs during acute alveolar hypoxia."3.67Effects of pentoxifylline on pulmonary hemodynamics during acute hypoxia in anesthetized dogs. ( Chick, TW; Doyle, MP; Icenogle, MV; Loeppky, JA; Riedel, CE; Scotto, P; Sikes, CW; Wood, SC, 1988)
"Aminophylline was equally effective and selective in lowering PVR but not SVR during hypoxia."1.27Attenuation of pulmonary and systemic vasoconstriction with pentoxifylline and aminophylline. ( Hakim, TS; Petrella, J, 1988)
"Pentoxifylline (Pent) is a xanthine known to improve erythrocyte deformability and thought to have little effect on smooth muscle tone."1.27Reversal of pulmonary hypoxic vasoconstriction with pentoxifylline and aminophylline in isolated lungs. ( Hakim, TS, 1988)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's2 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
REICHERTZ, P1
Palareti, G1
Coccheri, S1
Poggi, M1
Tricarico, MG1
Magelli, M1
Cavazzuti, F1
Steen, PA1
Michenfelder, JD1
Park, TS1
Gonzales, ER1
Shah, AR1
Gidday, JM1
Chen, J1
Dinger, B1
Fidone, SJ1
Stefanovich, V1
John, JP1
Hershenson, MB1
Schena, JA1
Lozano, PA1
Jacobson, MJ1
Crone, RK1
Hakim, TS2
Petrella, J1
Chick, TW1
Scotto, P1
Icenogle, MV1
Sikes, CW1
Doyle, MP1
Riedel, CE1
Wood, SC1
Loeppky, JA1

Other Studies

10 other studies available for theobromine and Hypoxia

ArticleYear
[THE EFFECT OF 7-(2-HYDROXY-3-(N-2-HYDROXYETHYL-N-METHYLAMINO)-PROPYL-THEOPHYLLINE NICOTINATE AND OTHER PURINE BODIES ON THE RESPIRATION AND ELECTROCARDIOGRAM OF GUINEA PIGS AND RATS IN HISTOTOXIC OXYGEN DEFICIENCY].
    Arzneimittel-Forschung, 1963, Volume: 13

    Topics: Cyanides; Electrocardiography; Guinea Pigs; Hypoxia; Niacin; Nicotinic Acids; Oxygen; Pharmacology;

1963
Changes in the rheologic properties of blood after a high altitude expedition.
    Angiology, 1984, Volume: 35, Issue:7

    Topics: Adult; Altitude Sickness; Blood Circulation; Blood Platelets; Blood Viscosity; Erythrocytes; Humans;

1984
Pentoxifylline does not protect mice against hypoxia.
    Acta anaesthesiologica Scandinavica, 1981, Volume: 25, Issue:2

    Topics: Animals; Cerebrovascular Circulation; Disease Models, Animal; Energy Metabolism; Hypoxia; Mice; Mice

1981
Hypoglycemia selectively abolishes hypoxic reactivity of pial arterioles in piglets: role of adenosine.
    The American journal of physiology, 1995, Volume: 268, Issue:2 Pt 2

    Topics: Adenosine; Animals; Animals, Newborn; Arterioles; Hemodynamics; Hypercapnia; Hypoglycemia; Hypoxia;

1995
cAMP production in rabbit carotid body: role of adenosine.
    Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 82, Issue:6

    Topics: Adenosine; Animals; Carotid Body; Cyclic AMP; Dipyridamole; Hypoxia; In Vitro Techniques; Phenethyla

1997
Influence of pentifylline on brain metabolism of normal and anoxic rats.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:11

    Topics: Adenine Nucleotides; Animals; Brain; Carbohydrate Metabolism; Creatine; Female; Hypoxia; Rats; Theob

1978
Effect of pentoxiphylline on oxygen transport during hypothermia.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:1

    Topics: Animals; Biological Availability; Biological Transport; Blood Viscosity; Dogs; Hypothermia; Hypoxia;

1989
Attenuation of pulmonary and systemic vasoconstriction with pentoxifylline and aminophylline.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:4

    Topics: Aminophylline; Angiotensin II; Animals; Dogs; Hemodynamics; Hypoxia; Lung; Pentoxifylline; Swine; Th

1988
Effects of pentoxifylline on pulmonary hemodynamics during acute hypoxia in anesthetized dogs.
    The American review of respiratory disease, 1988, Volume: 137, Issue:5

    Topics: Acute Disease; Animals; Blood Pressure; Blood Viscosity; Cardiac Output; Dogs; Erythrocyte Deformabi

1988
Reversal of pulmonary hypoxic vasoconstriction with pentoxifylline and aminophylline in isolated lungs.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:2

    Topics: Aminophylline; Animals; Blood Gas Analysis; Blood Pressure; Female; Hypoxia; In Vitro Techniques; Lu

1988