Page last updated: 2024-11-05

theobromine and Heroin Abuse

theobromine has been researched along with Heroin Abuse in 2 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Research Excerpts

ExcerptRelevanceReference
"Caffeine was rapidly and effectively absorbed after inhalation."2.71Population pharmacokinetics of caffeine and its metabolites theobromine, paraxanthine and theophylline after inhalation in combination with diacetylmorphine. ( Beijnen, JH; de Jonge, ME; den Hoed, R; Hendriks, VM; Huitema, AD; Sparidans, RW; van den Brink, W; van Ree, JM; Zandvliet, AS, 2005)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zandvliet, AS1
Huitema, AD1
de Jonge, ME1
den Hoed, R1
Sparidans, RW1
Hendriks, VM1
van den Brink, W1
van Ree, JM1
Beijnen, JH1
Yao, L1
McFarland, K1
Fan, P1
Jiang, Z1
Ueda, T1
Diamond, I1

Trials

1 trial available for theobromine and Heroin Abuse

ArticleYear
Population pharmacokinetics of caffeine and its metabolites theobromine, paraxanthine and theophylline after inhalation in combination with diacetylmorphine.
    Basic & clinical pharmacology & toxicology, 2005, Volume: 96, Issue:1

    Topics: Administration, Inhalation; Administration, Oral; Biological Availability; Caffeine; Central Nervous

2005

Other Studies

1 other study available for theobromine and Heroin Abuse

ArticleYear
Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, May-16, Volume: 103, Issue:20

    Topics: Adenosine A2 Receptor Antagonists; Analgesics, Opioid; Animals; Arachidonic Acids; Behavior, Animal;

2006