theobromine has been researched along with Fibrocystic Breast Disease in 2 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Fibrocystic Breast Disease: A common and benign breast disease characterized by varying degree of fibrocystic changes in the breast tissue. There are three major patterns of morphological changes, including FIBROSIS, formation of CYSTS, and proliferation of glandular tissue (adenosis). The fibrocystic breast has a dense irregular, lumpy, bumpy consistency.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Before establishing dosage levels for a chronic toxicity study, the pharmacokinetics of the dose must be determined in the species that will be used in long-term studies." | 2.36 | The toxicology of cocoa and methylxanthines: a review of the literature. ( Tarka, SM, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tarka, SM | 1 |
| Rohan, TE | 1 |
| Cook, MG | 1 |
| McMichael, AJ | 1 |
2 reviews available for theobromine and Fibrocystic Breast Disease
| Article | Year |
|---|---|
The toxicology of cocoa and methylxanthines: a review of the literature.
Topics: Animals; Cacao; Caffeine; Diet; Female; Fetus; Fibrocystic Breast Disease; Humans; Mutagenicity Test | 1982 |
Methylxanthines and benign proliferative epithelial disorders of the breast in women.
Topics: Adolescent; Adult; Aged; Biopsy; Breast; Caffeine; Case-Control Studies; Female; Fibrocystic Breast | 1989 |