theobromine has been researched along with Experimental Neoplasms in 4 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Short-term administration of pentoxifylline concurrent with intraportal or intravenous instillation of W163 adenocarcinoma was ineffective in preventing tumor cell implantation in adult male rats." | 3.66 | The role of pentoxifylline in the prevention of tumor cell implantation. ( Ambrus, JL; Ikossi-O'Connor, MG, 1983) |
| "Pentoxifylline (Trental), a phosphodiesterase inhibitor with platelet aggregation inhibitory effect, was shown to decrease spontaneous metastases in a Wilms' tumor model in Furth-Wistar rats and in neuroblastoma C1300 in A/J mice." | 3.66 | Studies on platelet aggregation inhibitors in vivo. VIII. Effect of pentoxifylline on spontaneous tumor metastasis. ( Ambrus, JL; Cohen, H; Gastpar, H; Gordon, S; Murphy, GP; Sciandra, J; Williams, P; Witul, M, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| GELLHORN, A | 1 |
| KELLS, A | 1 |
| HIRSCHBERG, E | 1 |
| Ikossi-O'Connor, MG | 1 |
| Ambrus, JL | 2 |
| Gil, M | 1 |
| Skopińska-Rózewska, E | 1 |
| Radomska, D | 1 |
| Demkow, U | 1 |
| Skurzak, H | 1 |
| Rochowska, M | 1 |
| Beuth, J | 1 |
| Roszkowski, K | 1 |
| Gordon, S | 1 |
| Witul, M | 1 |
| Cohen, H | 1 |
| Sciandra, J | 1 |
| Williams, P | 1 |
| Gastpar, H | 1 |
| Murphy, GP | 1 |
4 other studies available for theobromine and Experimental Neoplasms
| Article | Year |
|---|---|
Tests of compounds against various experimental tumors.
Topics: Animals; Humans; Imidazoles; Leukemia, Experimental; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms, Exp | 1953 |
The role of pentoxifylline in the prevention of tumor cell implantation.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Neoplasm Transplantation; Neoplasms, Experimental; N | 1983 |
Effect of purinergic receptor antagonists suramin and theobromine on tumor-induced angiogenesis in BALB/c mice.
Topics: Animals; Carcinoma; Injections, Subcutaneous; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neopl | 1993 |
Studies on platelet aggregation inhibitors in vivo. VIII. Effect of pentoxifylline on spontaneous tumor metastasis.
Topics: Adenocarcinoma; Animals; Lung Neoplasms; Male; Mice; Mice, Inbred A; Mice, Inbred BALB C; Neoplasm M | 1979 |