theobromine has been researched along with Diabetic Retinopathy in 8 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A long-term trial with oral pentoxifylline ("Trental" 400) in a dosage of 1200 mg per day was carried out in 70 diabetic patients with and without vascular afflictions." | 1.27 | Diabetic retinal vascular complications and erythrocyte filtrability; results of a 2-year follow-up study with pentoxifylline. ( Ferrari, E; Solerte, SB, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gol'tseva, SV | 1 |
| Pozza, G | 1 |
| Cordaro, C | 1 |
| Carandente, O | 1 |
| Margonato, A | 1 |
| Skopiński, P | 1 |
| Zukowska, M | 1 |
| Małkowska-Zwierz, W | 1 |
| Radomska, D | 1 |
| Retelska, D | 1 |
| Kecik, D | 1 |
| Domosławski, M | 1 |
| Sobczyńska, A | 1 |
| Pawińska, M | 1 |
| Skopińska-Rózewska, E | 1 |
| Colombati, S | 1 |
| Monti, L | 1 |
| Baggiani, M | 1 |
| Filippini, F | 1 |
| Ferrari, E | 2 |
| Fioravanti, M | 1 |
| Patti, AL | 1 |
| Viola, C | 1 |
| Solerte, SB | 2 |
| Zielinski, HW | 1 |
| Stark, H | 1 |
1 trial available for theobromine and Diabetic Retinopathy
| Article | Year |
|---|---|
[The treatment of retinal circulatory disorders in practice. A contribution to the cooperation between the internist and the ophthalmologist].
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Blood Circulation; Clinical Trials as Topic; Diabetic Ret | 1965 |
7 other studies available for theobromine and Diabetic Retinopathy
| Article | Year |
|---|---|
[Comparative evaluation of the efficacy of various methods in the treatment of diabetic retinopathies].
Topics: Adult; Aged; Blood Viscosity; Diabetic Retinopathy; Female; Humans; Male; Middle Aged; Pentoxifyllin | 1983 |
Study on relationship between erythrocyte filtration and other risk factors in diabetic angiopathy.
Topics: Diabetes Mellitus, Type 1; Diabetic Retinopathy; Erythrocytes; Female; Fibrinogen; Humans; Male; Pen | 1981 |
The effect of TPP, theophylline and theobromine on the angiogenic activity of mononuclear leucocytes obtained from diabetic patients with proliferative retinopathy.
Topics: Adolescent; Adult; Amino Acids; Animals; Carbohydrates; Child; Diabetic Retinopathy; Drug Combinatio | 1993 |
[Effects of pentoxifylline on the ocular rheographic pulse in diabetic patients].
Topics: Adult; Blood Circulation; Diabetic Retinopathy; Female; Humans; Male; Microcirculation; Middle Aged; | 1989 |
Effects of long-term treatment (4 years) with pentoxifylline on haemorheological changes and vascular complications in diabetic patients.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephrop | 1987 |
Diabetic retinal vascular complications and erythrocyte filtrability; results of a 2-year follow-up study with pentoxifylline.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopath | 1985 |
[Experience with Cosaldon in the treatment of circulatory disorders in the ophthalmological practice].
Topics: Arteriosclerosis; Diabetic Retinopathy; Glaucoma; Humans; Ophthalmoplegia; Optic Nerve; Retinal Dege | 1969 |