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theobromine and Diabetic Angiopathies

theobromine has been researched along with Diabetic Angiopathies in 18 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Diabetic Angiopathies: VASCULAR DISEASES that are associated with DIABETES MELLITUS.

Research Excerpts

ExcerptRelevanceReference
"A study was carried out in 127 patients (94 males and 33 females) presenting with arteriosclerosis (88 patients) or diabetic vasculopathy (39 patients) in different stages of severity (Fontaine) to assess the effectiveness and tolerance of treatment with high doses of pentoxifylline."3.67Results of clinical, laboratory and haemorheological investigations of the use of pentoxifylline in high doses. ( Antignani, PL; Bartolo, M; Pacino, G; Saliceti, F; Todini, AR, 1987)
"Pentoxifylline was used in the treatment of 90 patients with atherosclerosis-induced chronic peripheral arterial occlusive disease and diabetic vascular disorders in the lower extremities (clinical Fontaine Stages III and IV) for whom surgical reconstructive treatment was not indicated and who had shown inadequate response to previous therapy."1.27Clinical investigation of the effects of pentoxifylline in patients with severe peripheral occlusive vascular disease. ( Seige, K; Sternitzky, R, 1985)
"A long-term trial with oral pentoxifylline ("Trental" 400) in a dosage of 1200 mg per day was carried out in 70 diabetic patients with and without vascular afflictions."1.27Diabetic retinal vascular complications and erythrocyte filtrability; results of a 2-year follow-up study with pentoxifylline. ( Ferrari, E; Solerte, SB, 1985)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199018 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campbell, RK1
Baker, DE1
Moratti, F1
Cortiana, M1
Taglioretti, D1
Petruzzi, E1
Bucalossi, A1
Corri, S1
Marsilii, A1
Di Noto, C1
Valentini, M1
Sciannameo, F1
Francucci, M1
Tockner, M1
Sassano, L1
Allegra, A1
Spesivtseva, VG1
Kasabian, IN1
Mamaeva, GG1
Kukes, VG1
Pampulov, L2
Todorova, S1
Vogralik, VG1
Vogralik, MV1
Runov, GP1
Runova, AA1
Kostrov, AI1
Kolarov, P1
Veleva, N1
Nobbe, F1
Schubotz, R1
Mühlfellner, O1
Schwartz, RW1
Logan, NM1
Johnson, PJ1
Strodel, WE1
Fine, JG1
Kazmers, A1
Hyde, GL1
Jarcusková, D1
Uhrík, J1
Nazarova, KhI1
Gómez Reyes, D1
Rojas Hidalgo, E1
Ferrari, E2
Fioravanti, M1
Patti, AL1
Viola, C1
Solerte, SB2
Antignani, PL1
Todini, AR1
Saliceti, F1
Pacino, G1
Bartolo, M1
Sternitzky, R1
Seige, K1

Reviews

1 review available for theobromine and Diabetic Angiopathies

ArticleYear
Clinical considerations and treatment of diabetic angiopathy.
    Journal of medicine, 1979, Volume: 10, Issue:5

    Topics: Adult; Arterial Occlusive Diseases; Coronary Disease; Diabetic Angiopathies; Humans; Intermittent Cl

1979

Trials

3 trials available for theobromine and Diabetic Angiopathies

ArticleYear
[Erythrocyte filterability and treatment with pentoxifylline].
    La Ricerca in clinica e in laboratorio, 1983, Volume: 13 Suppl 3

    Topics: Diabetes Mellitus, Type 1; Diabetic Angiopathies; Erythrocytes; Humans; Middle Aged; Oxygen Consumpt

1983
[Use of trental and complamine in the microcirculatory disorders of diabetes mellitus].
    Sovetskaia meditsina, 1980, Issue:2

    Topics: Adult; Aged; Blood; Clinical Trials as Topic; Diabetic Angiopathies; Diabetic Nephropathies; Female;

1980
[Therapeutic effect of Trental in diabetic angiopathy].
    Vutreshni bolesti, 1978, Volume: 17, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Diabetic Angiopathies; Drug Evaluation; Electrocardiography;

1978

Other Studies

14 other studies available for theobromine and Diabetic Angiopathies

ArticleYear
Trental: a new medication for diabetic peripheral vascular disorders.
    The Diabetes educator, 1984,Summer, Volume: 10, Issue:2

    Topics: Diabetic Angiopathies; Humans; Pentoxifylline; Theobromine

1984
[Use of erythrocyte filtration in the study of diabetic vasculopathy. Therapeutic efficacy of pentoxifylline].
    La Clinica terapeutica, 1983, Jul-15, Volume: 106, Issue:1

    Topics: Diabetic Angiopathies; Erythrocyte Aggregation; Erythrocytes; Female; Filtration; Humans; Male; Pent

1983
[Use of pentoxifylline in diabetes with intermittent claudication].
    La Ricerca in clinica e in laboratorio, 1983, Volume: 13 Suppl 3

    Topics: Cholesterol; Diabetic Angiopathies; Erythrocytes; Fibrinogen; Glycated Hemoglobin; Humans; Intermitt

1983
[Treatment of diabetic angiopathy with pentoxifylline].
    Vutreshni bolesti, 1982, Volume: 21, Issue:3

    Topics: Adult; Aged; Amputation, Surgical; Diabetic Angiopathies; Female; Humans; Leg; Male; Middle Aged; Pe

1982
[Trental treatment of microcirculatory disorders in diabetes mellitus and arteriosclerosis].
    Klinicheskaia meditsina, 1982, Volume: 60, Issue:10

    Topics: Adolescent; Adult; Aged; Arteriosclerosis; Blood Viscosity; Diabetic Angiopathies; Drug Evaluation;

1982
The effect of pentoxifylline on erythrocyte deformability and on phosphatide fatty acid distribution in the erythrocyte membrane.
    Current medical research and opinion, 1977, Volume: 4, Issue:9

    Topics: Aged; Diabetic Angiopathies; Erythrocyte Membrane; Erythrocytes; Fatty Acids; Female; Humans; Male;

1977
Pentoxifylline increases extremity blood flow in diabetic atherosclerotic patients.
    Archives of surgery (Chicago, Ill. : 1960), 1989, Volume: 124, Issue:4

    Topics: Arteries; Arteriosclerosis; Diabetes Mellitus; Diabetic Angiopathies; Exercise Test; Female; Humans;

1989
[Evaluation of thermal conductivity and skin temperature in the treatment of leg ulcers].
    Bratislavske lekarske listy, 1988, Volume: 89, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Diabetic Angiopathies; Female; Humans; Leg; Leg Ul

1988
[Effect of the long-term prophylactic use of trental on cerebral blood flow in diabetics].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:9

    Topics: Adult; Cerebrovascular Disorders; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Diabet

1988
[Therapeutic results with xanthine derivatives in the intermittent claudication syndrome in diabetic patients].
    Revista clinica espanola, 1988, Volume: 182, Issue:1

    Topics: Adult; Aged; Diabetic Angiopathies; Drug Therapy, Combination; Female; Humans; Intermittent Claudica

1988
Effects of long-term treatment (4 years) with pentoxifylline on haemorheological changes and vascular complications in diabetic patients.
    Pharmatherapeutica, 1987, Volume: 5, Issue:1

    Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephrop

1987
Results of clinical, laboratory and haemorheological investigations of the use of pentoxifylline in high doses.
    Pharmatherapeutica, 1987, Volume: 5, Issue:1

    Topics: Aged; Arteriosclerosis; Blood Pressure; Diabetic Angiopathies; Erythrocyte Deformability; Female; Hu

1987
Clinical investigation of the effects of pentoxifylline in patients with severe peripheral occlusive vascular disease.
    Current medical research and opinion, 1985, Volume: 9, Issue:9

    Topics: Adult; Aged; Arterial Occlusive Diseases; Arteriosclerosis; Diabetes Mellitus, Type 1; Diabetes Mell

1985
Diabetic retinal vascular complications and erythrocyte filtrability; results of a 2-year follow-up study with pentoxifylline.
    Pharmatherapeutica, 1985, Volume: 4, Issue:6

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopath

1985