theobromine has been researched along with Diabetic Angiopathies in 18 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Diabetic Angiopathies: VASCULAR DISEASES that are associated with DIABETES MELLITUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A study was carried out in 127 patients (94 males and 33 females) presenting with arteriosclerosis (88 patients) or diabetic vasculopathy (39 patients) in different stages of severity (Fontaine) to assess the effectiveness and tolerance of treatment with high doses of pentoxifylline." | 3.67 | Results of clinical, laboratory and haemorheological investigations of the use of pentoxifylline in high doses. ( Antignani, PL; Bartolo, M; Pacino, G; Saliceti, F; Todini, AR, 1987) |
| "Pentoxifylline was used in the treatment of 90 patients with atherosclerosis-induced chronic peripheral arterial occlusive disease and diabetic vascular disorders in the lower extremities (clinical Fontaine Stages III and IV) for whom surgical reconstructive treatment was not indicated and who had shown inadequate response to previous therapy." | 1.27 | Clinical investigation of the effects of pentoxifylline in patients with severe peripheral occlusive vascular disease. ( Seige, K; Sternitzky, R, 1985) |
| "A long-term trial with oral pentoxifylline ("Trental" 400) in a dosage of 1200 mg per day was carried out in 70 diabetic patients with and without vascular afflictions." | 1.27 | Diabetic retinal vascular complications and erythrocyte filtrability; results of a 2-year follow-up study with pentoxifylline. ( Ferrari, E; Solerte, SB, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Campbell, RK | 1 |
| Baker, DE | 1 |
| Moratti, F | 1 |
| Cortiana, M | 1 |
| Taglioretti, D | 1 |
| Petruzzi, E | 1 |
| Bucalossi, A | 1 |
| Corri, S | 1 |
| Marsilii, A | 1 |
| Di Noto, C | 1 |
| Valentini, M | 1 |
| Sciannameo, F | 1 |
| Francucci, M | 1 |
| Tockner, M | 1 |
| Sassano, L | 1 |
| Allegra, A | 1 |
| Spesivtseva, VG | 1 |
| Kasabian, IN | 1 |
| Mamaeva, GG | 1 |
| Kukes, VG | 1 |
| Pampulov, L | 2 |
| Todorova, S | 1 |
| Vogralik, VG | 1 |
| Vogralik, MV | 1 |
| Runov, GP | 1 |
| Runova, AA | 1 |
| Kostrov, AI | 1 |
| Kolarov, P | 1 |
| Veleva, N | 1 |
| Nobbe, F | 1 |
| Schubotz, R | 1 |
| Mühlfellner, O | 1 |
| Schwartz, RW | 1 |
| Logan, NM | 1 |
| Johnson, PJ | 1 |
| Strodel, WE | 1 |
| Fine, JG | 1 |
| Kazmers, A | 1 |
| Hyde, GL | 1 |
| Jarcusková, D | 1 |
| Uhrík, J | 1 |
| Nazarova, KhI | 1 |
| Gómez Reyes, D | 1 |
| Rojas Hidalgo, E | 1 |
| Ferrari, E | 2 |
| Fioravanti, M | 1 |
| Patti, AL | 1 |
| Viola, C | 1 |
| Solerte, SB | 2 |
| Antignani, PL | 1 |
| Todini, AR | 1 |
| Saliceti, F | 1 |
| Pacino, G | 1 |
| Bartolo, M | 1 |
| Sternitzky, R | 1 |
| Seige, K | 1 |
1 review available for theobromine and Diabetic Angiopathies
| Article | Year |
|---|---|
Clinical considerations and treatment of diabetic angiopathy.
Topics: Adult; Arterial Occlusive Diseases; Coronary Disease; Diabetic Angiopathies; Humans; Intermittent Cl | 1979 |
3 trials available for theobromine and Diabetic Angiopathies
| Article | Year |
|---|---|
[Erythrocyte filterability and treatment with pentoxifylline].
Topics: Diabetes Mellitus, Type 1; Diabetic Angiopathies; Erythrocytes; Humans; Middle Aged; Oxygen Consumpt | 1983 |
[Use of trental and complamine in the microcirculatory disorders of diabetes mellitus].
Topics: Adult; Aged; Blood; Clinical Trials as Topic; Diabetic Angiopathies; Diabetic Nephropathies; Female; | 1980 |
[Therapeutic effect of Trental in diabetic angiopathy].
Topics: Adult; Aged; Clinical Trials as Topic; Diabetic Angiopathies; Drug Evaluation; Electrocardiography; | 1978 |
14 other studies available for theobromine and Diabetic Angiopathies
| Article | Year |
|---|---|
Trental: a new medication for diabetic peripheral vascular disorders.
Topics: Diabetic Angiopathies; Humans; Pentoxifylline; Theobromine | 1984 |
[Use of erythrocyte filtration in the study of diabetic vasculopathy. Therapeutic efficacy of pentoxifylline].
Topics: Diabetic Angiopathies; Erythrocyte Aggregation; Erythrocytes; Female; Filtration; Humans; Male; Pent | 1983 |
[Use of pentoxifylline in diabetes with intermittent claudication].
Topics: Cholesterol; Diabetic Angiopathies; Erythrocytes; Fibrinogen; Glycated Hemoglobin; Humans; Intermitt | 1983 |
[Treatment of diabetic angiopathy with pentoxifylline].
Topics: Adult; Aged; Amputation, Surgical; Diabetic Angiopathies; Female; Humans; Leg; Male; Middle Aged; Pe | 1982 |
[Trental treatment of microcirculatory disorders in diabetes mellitus and arteriosclerosis].
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Blood Viscosity; Diabetic Angiopathies; Drug Evaluation; | 1982 |
The effect of pentoxifylline on erythrocyte deformability and on phosphatide fatty acid distribution in the erythrocyte membrane.
Topics: Aged; Diabetic Angiopathies; Erythrocyte Membrane; Erythrocytes; Fatty Acids; Female; Humans; Male; | 1977 |
Pentoxifylline increases extremity blood flow in diabetic atherosclerotic patients.
Topics: Arteries; Arteriosclerosis; Diabetes Mellitus; Diabetic Angiopathies; Exercise Test; Female; Humans; | 1989 |
[Evaluation of thermal conductivity and skin temperature in the treatment of leg ulcers].
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Diabetic Angiopathies; Female; Humans; Leg; Leg Ul | 1988 |
[Effect of the long-term prophylactic use of trental on cerebral blood flow in diabetics].
Topics: Adult; Cerebrovascular Disorders; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Diabet | 1988 |
[Therapeutic results with xanthine derivatives in the intermittent claudication syndrome in diabetic patients].
Topics: Adult; Aged; Diabetic Angiopathies; Drug Therapy, Combination; Female; Humans; Intermittent Claudica | 1988 |
Effects of long-term treatment (4 years) with pentoxifylline on haemorheological changes and vascular complications in diabetic patients.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephrop | 1987 |
Results of clinical, laboratory and haemorheological investigations of the use of pentoxifylline in high doses.
Topics: Aged; Arteriosclerosis; Blood Pressure; Diabetic Angiopathies; Erythrocyte Deformability; Female; Hu | 1987 |
Clinical investigation of the effects of pentoxifylline in patients with severe peripheral occlusive vascular disease.
Topics: Adult; Aged; Arterial Occlusive Diseases; Arteriosclerosis; Diabetes Mellitus, Type 1; Diabetes Mell | 1985 |
Diabetic retinal vascular complications and erythrocyte filtrability; results of a 2-year follow-up study with pentoxifylline.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopath | 1985 |