theobromine has been researched along with Dental Caries in 5 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Dental Caries: Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Theobromine (TB) has been reported to promote tooth remineralization, strengthen tooth substance, and relieve dentin hypersensitivity." | 1.91 | Bacterial adhesion and antibacterial property of coating materials containing theobromine and S-PRG filler. ( Burrow, MF; Hotta, M; Ichimura, Y; Ikeda, M; Kitada, N; Kusakabe, S; Nikaido, T; Shimizu, S; Takagaki, T; Toyama, M; Yamamoto, K, 2023) |
| "Early carious lesions were created in 272 bovine enamel specimens and assigned to sixteen groups (n=17) based on Knoop surface microhardness (SMH)." | 1.56 | The effect of theobromine on the in vitro de- and remineralization of enamel carious lesions. ( Eckert, GJ; Levon, JA; Lin, WS; Lippert, F; Morton, D; Thorn, AK, 2020) |
| "F+theobromine was similar to F." | 1.46 | The effects of fluoride, strontium, theobromine and their combinations on caries lesion rehardening and fluoridation. ( Lippert, F, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shimizu, S | 2 |
| Kusakabe, S | 2 |
| Toyama, M | 2 |
| Takagaki, T | 2 |
| Kitada, N | 2 |
| Yamamoto, K | 2 |
| Ikeda, M | 2 |
| Ichimura, Y | 2 |
| Burrow, MF | 2 |
| Hotta, M | 2 |
| Nikaido, T | 2 |
| Nassar, HM | 1 |
| Lippert, F | 3 |
| Thorn, AK | 1 |
| Lin, WS | 1 |
| Levon, JA | 1 |
| Morton, D | 1 |
| Eckert, GJ | 1 |
| Amaechi, BT | 1 |
| Porteous, N | 1 |
| Ramalingam, K | 1 |
| Mensinkai, PK | 1 |
| Ccahuana Vasquez, RA | 1 |
| Sadeghpour, A | 1 |
| Nakamoto, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effectiveness Evaluation of the Theobromine Containing Toothpastes in Controlling Dental Plaque in Children Aged 6-9years(Randomized Controlled Clinical Trial)[NCT05187507] | 80 participants (Actual) | Interventional | 2021-09-25 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for theobromine and Dental Caries
| Article | Year |
|---|---|
Remineralization of artificial enamel lesions by theobromine.
Topics: Calcium; Cariostatic Agents; Dental Caries; Dental Enamel; Electron Probe Microanalysis; Hardness; H | 2013 |
4 other studies available for theobromine and Dental Caries
| Article | Year |
|---|---|
Bacterial adhesion and antibacterial property of coating materials containing theobromine and S-PRG filler.
Topics: Anti-Bacterial Agents; Bacterial Adhesion; Dental Caries; Glass Ionomer Cements; Humans; Theobromine | 2023 |
Bacterial adhesion and antibacterial property of coating materials containing theobromine and S-PRG filler.
Topics: Anti-Bacterial Agents; Bacterial Adhesion; Dental Caries; Glass Ionomer Cements; Humans; Theobromine | 2023 |
Bacterial adhesion and antibacterial property of coating materials containing theobromine and S-PRG filler.
Topics: Anti-Bacterial Agents; Bacterial Adhesion; Dental Caries; Glass Ionomer Cements; Humans; Theobromine | 2023 |
Bacterial adhesion and antibacterial property of coating materials containing theobromine and S-PRG filler.
Topics: Anti-Bacterial Agents; Bacterial Adhesion; Dental Caries; Glass Ionomer Cements; Humans; Theobromine | 2023 |
Artificial Caries Lesion Characteristics after Secondary Demineralization with Theobromine-Containing Protocol.
Topics: Animals; Bronchodilator Agents; Cattle; Dental Caries; Dental Enamel; Fluorides; Theobromine; Tooth; | 2021 |
The effect of theobromine on the in vitro de- and remineralization of enamel carious lesions.
Topics: Animals; Cariostatic Agents; Cattle; Dental Caries; Dental Enamel; Fluorides; Hardness; Humans; Hydr | 2020 |
The effects of fluoride, strontium, theobromine and their combinations on caries lesion rehardening and fluoridation.
Topics: Dental Caries; Drug Synergism; Fluoridation; Fluorides; Hardness Tests; Humans; Hydrogen-Ion Concent | 2017 |