theobromine has been researched along with Dementia in 8 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
Excerpt | Relevance | Reference |
---|---|---|
"Twenty outpatients (8 women and 12 men; age range 52-66 years) with mild to moderate degree of cerebrovascular disorders and arteriosclerotic dementia, were randomly assigned to either control or pentoxifylline group (400 mg X 3/day/4 weeks p." | 5.05 | Cerebral blood flow in patients with cerebrovascular disorders: study with pentoxifylline. ( Hartmann, A, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (87.50) | 18.7374 |
1990's | 1 (12.50) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
COOPER, AJ | 1 |
Hartmann, A | 2 |
Dormehl, IC | 1 |
Jordaan, B | 1 |
Oliver, DW | 1 |
Croft, S | 1 |
Ghose, K | 1 |
Parnetti, L | 2 |
Ciuffetti, G | 2 |
Mercuri, M | 2 |
Lupattelli, G | 1 |
Senin, U | 2 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Brain Changes in Pediatric Obstructive Sleep Apnea[NCT05368077] | 70 participants (Anticipated) | Interventional | 2022-05-14 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
6 trials available for theobromine and Dementia
Article | Year |
---|---|
Cerebral blood flow in patients with cerebrovascular disorders: study with pentoxifylline.
Topics: Aged; Cerebrovascular Circulation; Dementia; Female; Humans; Intracranial Arteriosclerosis; Male; Mi | 1981 |
SPECT monitoring of improved cerebral blood flow during long-term treatment of elderly patients with nootropic drugs.
Topics: Administration, Oral; Aged; Aging; Brain; Cerebellum; Cerebrovascular Circulation; Cognition; Cross- | 1999 |
Oxpentifylline in dementia: a controlled study.
Topics: Aged; Dementia; Double-Blind Method; Female; Humans; Male; Mental Processes; Mental Status Schedule; | 1987 |
The role of haemorheological factors in the ageing brain: long-term therapy with pentoxifylline ('Trental' 400) in elderly patients with initial mental deterioration.
Topics: Aged; Aging; Blood Viscosity; Cerebrovascular Circulation; Dementia; Erythrocyte Deformability; Fema | 1986 |
Haemorheological pattern in initial mental deterioration: results of a long-term study using piracetam and pentoxifylline.
Topics: Aged; Clinical Trials as Topic; Dementia; Drug Therapy, Combination; Female; Humans; Male; Mental Re | 1985 |
Comparative randomized study of cerebral blood flow after long-term administration of pentoxifylline and co-dergocrine mesylate in patients with chronic cerebrovascular disease.
Topics: Aged; Blood Flow Velocity; Cerebrovascular Circulation; Dementia; Dihydroergotoxine; Female; Humans; | 1985 |
2 other studies available for theobromine and Dementia
Article | Year |
---|---|
A CONTROLLED TRIAL OF COSALDON IN ARTERIOSCLEROTIC DEMENTIA.
Topics: Arteriosclerosis; Biomedical Research; Cerebrovascular Disorders; Dementia; Dementia, Vascular; Drug | 1964 |
Drugs for dementia.
Topics: Aged; Cyclandelate; Dementia; Dihydroergotoxine; Female; Humans; Isoxsuprine; Male; Meclofenoxate; M | 1975 |