theobromine has been researched along with Cough in 6 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cough is a common and protective reflex, but persistent coughing is debilitating and impairs quality of life." | 6.71 | Theobromine inhibits sensory nerve activation and cough. ( Barnes, PJ; Belvisi, MG; Birrell, MA; Crispino, N; Korbonits, D; Korbonits, M; Patel, HJ; Usmani, OS, 2005) |
| " The benefits of methylxanthine-based therapies in the apnea of prematurity and their translational potential in pediatric affections of the respiratory tract are here presented." | 4.93 | The potential of methylxanthine-based therapies in pediatric respiratory tract diseases. ( Franco, R; Martínez-Pinilla, E; Oñatibia-Astibia, A, 2016) |
| "In this study the effects of non-selective PDE inhibitors (theophylline and theobromine) and selective inhibitors of PDE 1, 3, 4 and 5 on cough, induced by citric acid, were evaluated." | 3.77 | The influence of the PDE inhibitors on cough reflex in guinea pigs. ( Mokry, J; Nosalova, G, 2011) |
| "Evaluate the potential inhibition of cough in a mouse model induced by sulfur dioxide gas of methanol and chloroform extracts of aerial parts of Chamaedorea tepejilote." | 3.74 | Evaluation of anti-tussive activity of Chamaedorea tepejilote. ( Pérez G, C; Pérez G, S; Ponce M, H; Ventura R, E; Zavala S, MA, 2008) |
| "Cough is a common and protective reflex, but persistent coughing is debilitating and impairs quality of life." | 2.71 | Theobromine inhibits sensory nerve activation and cough. ( Barnes, PJ; Belvisi, MG; Birrell, MA; Crispino, N; Korbonits, D; Korbonits, M; Patel, HJ; Usmani, OS, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oñatibia-Astibia, A | 1 |
| Martínez-Pinilla, E | 1 |
| Franco, R | 1 |
| Pérez G, C | 1 |
| Zavala S, MA | 1 |
| Ventura R, E | 1 |
| Pérez G, S | 1 |
| Ponce M, H | 1 |
| Mokry, J | 1 |
| Nosalova, G | 1 |
| Smith, B | 1 |
| Clancy, JA | 1 |
| Deuchars, SA | 1 |
| Deuchars, J | 1 |
| Usmani, OS | 1 |
| Belvisi, MG | 1 |
| Patel, HJ | 1 |
| Crispino, N | 1 |
| Birrell, MA | 1 |
| Korbonits, M | 1 |
| Korbonits, D | 1 |
| Barnes, PJ | 1 |
1 review available for theobromine and Cough
| Article | Year |
|---|---|
The potential of methylxanthine-based therapies in pediatric respiratory tract diseases.
Topics: Adolescent; Apnea; Asthma; Bronchodilator Agents; Caffeine; Child; Child, Preschool; Cough; Humans; | 2016 |
1 trial available for theobromine and Cough
| Article | Year |
|---|---|
Theobromine inhibits sensory nerve activation and cough.
Topics: Adult; Animals; Antitussive Agents; Capsaicin; Citric Acid; Codeine; Cough; Cross-Over Studies; Dise | 2005 |
4 other studies available for theobromine and Cough
| Article | Year |
|---|---|
Evaluation of anti-tussive activity of Chamaedorea tepejilote.
Topics: Administration, Oral; Animals; Antitussive Agents; Arecaceae; Cough; Disease Models, Animal; Dose-Re | 2008 |
The influence of the PDE inhibitors on cough reflex in guinea pigs.
Topics: Animals; Antitussive Agents; Bronchial Hyperreactivity; Citric Acid; Cough; Guinea Pigs; Male; Ovalb | 2011 |
Chocolate is no sweetener for concerns!
Topics: Cacao; Cough; Humans; Theobromine; United Kingdom | 2011 |
The wonders of the Wanderer.
Topics: Animals; Cacao; Cough; Depressive Disorder, Major; Epilepsy; Heart Failure; Hiccup; Humans; Theobrom | 2013 |